Group sequential designs for pragmatic clinical trials with early outcomes: methods and guidance for planning and implementation von Parsons, Nick R, Basu, Joydeep, Stallard, Nigel

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Group sequential designs in pragmatic trials: feasibility and assessment of utility using data from a number of recent surgical RCTs von Parsons, Nick R, Stallard, Nigel, Parsons, Helen, Haque, Aminul, Underwood, Martin, Mason, James, Khan, Iftekhar, Costa, Matthew L, Griffin, Damian R, Griffin, James, Beard, David J, Cook, Jonathan A, Davies, Loretta, Hudson, Jemma, Metcalfe, Andrew

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UK DRAFFT: a randomised controlled trial of percutaneous fixation with Kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displa... von Costa, Matthew L, Achten, Juul, Plant, Caroline, Parsons, Nick R, Rangan, Amar, Tubeuf, Sandy, Yu, Ge, Lamb, Sarah E

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Intramedullary nail fixation versus locking plate fixation for adults with a fracture of the distal tibia: the UK FixDT RCT von Costa, Matthew L, Achten, Juul, Hennings, Susie, Boota, Nafisa, Griffin, James, Petrou, Stavros, Maredza, Mandy, Dritsaki, Melina, Wood, Thomas, Masters, James, Pallister, Ian, Lamb, Sarah E, Parsons, Nick R

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Plaster cast versus functional bracing for Achilles tendon rupture: the UKSTAR RCT von Costa, Matthew L., Achten, Juul, Wagland, Susan, Marian, Ioana R., Maredza, Mandy, Schlussel, Michael Maia, Liew, Anna S., Parsons, Nick R., Dutton, Susan J., Kearney, Rebecca S., Lamb, Sarah E., Ollivere, Benjamin, Petrou, Stavros

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Unit of analysis issues in laboratory-based research von Parsons, Nick R, Teare, M Dawn, Sitch, Alice J

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An evaluation of the quality of statistical design and analysis of published medical research: results from a systematic survey of general orthopaedic journals von Parsons, Nick R, Price, Charlotte L, Hiskens, Richard, Achten, Juul, Costa, Matthew L

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Effect of Locking Plate Fixation vs Intramedullary Nail Fixation on 6-Month Disability Among Adults With Displaced Fracture of the Distal Tibia: The UK FixDT Randomized Clinical Tr... von Costa, Matthew L, Achten, Juul, Griffin, James, Petrou, Stavros, Pallister, Ian, Lamb, Sarah E, Parsons, Nick R

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Percutaneous fixation with Kirschner wires versus volar locking plate fixation in adults with dorsally displaced fracture of distal radius: randomised controlled trial von Costa, Matthew L, Achten, Juul, Parsons, Nick R, Rangan, Amar, Griffin, Damian, Tubeuf, Sandy, Lamb, Sarah E

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Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinica... von Costa, Matthew L, Achten, Juul, Bruce, Julie, Tutton, Elizabeth, Petrou, Stavros, Lamb, Sarah E, Parsons, Nick R

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Interventions for treating fractures of the distal femur in adults von Griffin, Xavier L, Claireaux, Henry A, Searle, Henry KC, Parsons, Nick R, Griffin, Xavier L

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Differences in Microbial Activity and Microbial Populations of Peat Associated with Suppression of Damping-Off Disease Caused by Pythium sylvaticum von Hunter, Paul J, Petch, Geoff M, Calvo-Bado, Leo A, Pettitt, Tim R, Parsons, Nick R, Morgan, J. Alun W, Whipps, John M

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Proportional-odds models for repeated composite and long ordinal outcome scales von Parsons, Nick R.

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A randomised controlled trial of total hip arthroplasty versus resurfacing arthroplasty in the treatment of young patients with arthritis of the hip joint von Achten, Juul, Parsons, Nick R, Edlin, Richard P, Griffin, Damian R, Costa, Matthew L

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The comprehensive cohort model in a pilot trial in orthopaedic trauma von Kearney, Rebecca S, Achten, Juul, Parsons, Nick R, Costa, Matthew L

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UK DRAFFT - a randomised controlled trial of percutaneous fixation with kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displ... von Costa, Matthew L, Achten, Juul, Parsons, Nick R, Rangan, Amar, Edlin, Richard P, Brown, Jaclyn, Lamb, Sarah E

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Interpreting and reporting fracture classification and operation type in hip fracture: implications for research studies and routine national audits von Masters, James, Metcalfe, David, Parsons, Nick R, Achten, Juul, Griffin, Xavier L, Costa, Matt L

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Protocol for a randomised controlled trial of standard wound management versus negative pressure wound therapy in the treatment of adult patients with an open fracture of the lower... von Achten, Juul, Parsons, Nick R, Bruce, Julie, Petrou, Stavros, Tutton, Elizabeth, Willett, Keith, Lamb, Sarah E, Costa, Matthew L

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Repeated measures proportional odds logistic regression analysis of ordinal score data in the statistical software package R von Parsons, Nick R., Costa, Matthew L., Achten, Juul, Stallard, Nigel

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A Comparison of Harris and Oxford Hip Scores for Assessing Outcome after Resurfacing Arthroplasty of the Hip: Can the Patient Tell us Everything we Need to Know? von Parsons, Nick R., De Souza, Ruth-Mary, Oni, Tofunmi, Achten, Juul, Krikler, Stephen J., Costa, Mattew L.

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