Carbamylation reduces the capacity of IgG for hexamerization and complement activation von Lubbers, R., Oostindie, S. C., Dijkstra, D. J., Parren, P. W. H. I., Verheul, M. K., Abendstein, L., Sharp, T. H., Ru, A., Janssen, G. M. C., Veelen, P. A., den Bremer, E. T. J., Bleijlevens, B., Kreuk, B.‐J., Beurskens, F. J., Trouw, L. A.

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Fusion proteins between ligands for NKG2D and CD20-directed single-chain variable fragments sensitize lymphoma cells for natural killer cell-mediated lysis and enhance antibody-dep... von Kellner, C, Hallack, D, Glorius, P, Staudinger, M, Mohseni Nodehi, S, de Weers, M, van de Winkel, J G J, Parren, P W H I, Stauch, M, Valerius, T, Repp, R, Humpe, A, Gramatzki, M, Peipp, M

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A novel label-free cell-based assay technology using biolayer interferometry von Verzijl, D., Riedl, T., Parren, P.W.H.I., Gerritsen, A.F.

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The therapeutic human CD38 antibody daratumumab improves the anti-myeloma effect of newly emerging multi-drug therapies von van der Veer, M S, de Weers, M, van Kessel, B, Bakker, J M, Wittebol, S, Parren, P W H I, Lokhorst, H M, Mutis, T

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Human kappa light chain targeted Pseudomonas exotoxin A — identifying human antibodies and Fab fragments with favorable characteristics for antibody–drug conjugate development von Kellner, C., Bleeker, W.K., Lammerts van Bueren, J.J., Staudinger, M., Klausz, K., Derer, S., Glorius, P., Muskulus, A., de Goeij, B.E.C.G., van de Winkel, J.G.J., Parren, P.W.H.I., Valerius, T., Gramatzki, M., Peipp, M.

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CD20‐Specific Immunoligands Engaging NKG2D Enhance γδ T Cell‐Mediated Lysis of Lymphoma Cells von Peipp, M., Wesch, D., Oberg, H.‐H., Lutz, S., Muskulus, A., Winkel, J. G. J., Parren, P. W. H. I., Burger, R., Humpe, A., Kabelitz, D., Gramatzki, M., Kellner, C.

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The novel tribody [(CD20)2xCD16] efficiently triggers effector cell-mediated lysis of malignant B cells von Glorius, P, Baerenwaldt, A, Kellner, C, Staudinger, M, Dechant, M, Stauch, M, Beurskens, F J, Parren, P W H I, Winkel, J G J van de, Valerius, T, Humpe, A, Repp, R, Gramatzki, M, Nimmerjahn, F, Peipp, M

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In situ depletion of CD4+ T cells in human skin by Zanolimumab von VILLADSEN, L. S, SKOV, L, DAM, T. N, DAGNAES-HANSEN, F, RYGAARD, J, SCHUURMAN, J, PARREN, P. W. H. I, VAN DE WINKEL, J. G. J, BAADSGAARD, O

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The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity von Parren, P W, Moore, J P, Burton, D R, Sattentau, Q J

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Human anti-nicotinic acetylcholine receptor recombinant Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant speci... von Graus, YF, de Baets, MH, Parren, PW, Berrih-Aknin, S, Wokke, J, van Breda Vriesman, PJ, Burton, DR

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Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy von Da Roit, Fabio, Engelberts, Patrick J, Taylor, Ronald P, Breij, Esther C W, Gritti, Giuseppe, Rambaldi, Alessandro, Introna, Martino, Parren, Paul W H I, Beurskens, Frank J, Golay, Josée

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Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma von Drent, Esther, Groen, Richard W J, Noort, Willy A, Themeli, Maria, Lammerts van Bueren, Jeroen J, Parren, Paul W H I, Kuball, Jürgen, Sebestyen, Zsolt, Yuan, Huipin, de Bruijn, Joost, van de Donk, Niels W C J, Martens, Anton C M, Lokhorst, Henk M, Mutis, Tuna

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Towards effective immunotherapy of myeloma: enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab von VAN DER VEER, Michael S, DE WEERS, Michel, VAN KESSEL, Berris, BAKKER, Joost M, WITTEBOL, Shulamiet, PARREN, Paul W. H. I, LOKHORST, Henk M, MUTIS, Tuna

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Efficient Neutralization of Primary Isolates of HIV-1 by a Recombinant Human Monoclonal Antibody von Burton, Dennis R., Pyati, Jayashree, Koduri, Raju, Sharp, Stephen J., Thornton, George B., Paul W. H. I. Parren, Lynette S. W. Sawyer, Hendry, R. Michael, Dunlop, Nancy, Nara, Peter L., Lamacchia, Michael, Garratty, Eileen, Stiehm, E. Richard, Bryson, Yvonne J., Cao, Yunzhen, Moore, John P., Ho, David D., Barbas, Carlos F.

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Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide von Nijhof, Inger S, Lammerts van Bueren, Jeroen J, van Kessel, Berris, Andre, Pascale, Morel, Yannis, Lokhorst, Henk M, van de Donk, Niels W C J, Parren, Paul W H I, Mutis, Tuna

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Absence of specific mucosal antibody responses in HIV-exposed uninfected sex workers from the Gambia von DORRELL, L, HESSELL, A. J, MENG WANG, WHITTLE, H, SABALLY, S, ROWLAND-JONES, S, BURTON, D. R, PARREN, P. W. H. I

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Crystal Structure of a Neutralizing Human IgG against HIV-1: A Template for Vaccine Design von Saphire, Erica Ollmann, Paul W. H. I. Parren, Pantophlet, Ralph, Zwick, Michael B., Morris, Garrett M., Rudd, Pauline M., Dwek, Raymond A., Stanfield, Robyn L., Burton, Dennis R., Wilson, Ian A.

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Antibody Protects Macaques against Vaginal Challenge with a Pathogenic R5 Simian/Human Immunodeficiency Virus at Serum Levels Giving Complete Neutralization In Vitro von Parren, P W, Marx, P A, Hessell, A J, Luckay, A, Harouse, J, Cheng-Mayer, C, Moore, J P, Burton, D R

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Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41 von Zwick, M B, Labrijn, A F, Wang, M, Spenlehauer, C, Saphire, E O, Binley, J M, Moore, J P, Stiegler, G, Katinger, H, Burton, D R, Parren, P W

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The in vivo mechanism of action of CD20 monoclonal antibodies depends on local tumor burden von BOROSS, Peter, MARCO JANSEN, J. H, LEUSEN, Jeanette H. W, DE HAIJ, Simone, BEURSKENS, Frank J, VAN DER POEL, Cees E, BEVAART, Lisette, NEDEREND, Maaike, GOLAY, Josée, VAN DE WINKEL, Jan G. J, PARREN, Paul W. H. I

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