Model Description Language (MDL): A Standard for Modeling and Simulation von Smith, Mike K., Moodie, Stuart L., Bizzotto, Roberto, Blaudez, Eric, Borella, Elisa, Carrara, Letizia, Chan, Phylinda, Chenel, Marylore, Comets, Emmanuelle, Gieschke, Ronald, Harling, Kajsa, Harnisch, Lutz, Hartung, Niklas, Hooker, Andrew C., Karlsson, Mats O., Kaye, Richard, Kloft, Charlotte, Kokash, Natallia, Lavielle, Marc, Lestini, Giulia, Magni, Paolo, Mari, Andrea, Mentré, France, Muselle, Chris, Nordgren, Rikard, Nyberg, Henrik B., Parra‐Guillén, Zinnia P., Pasotti, Lorenzo, Rode‐Kristensen, Niels, Sardu, Maria L., Smith, Gareth R., Swat, Maciej J., Terranova, Nadia, Yngman, Gunnar, Yvon, Florent, Holford, Nick

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The circadian rhythm of corticosteroid‐binding globulin has little impact on cortisol exposure after hydrocortisone dosing von Melin, Johanna, Hartung, Niklas, Parra‐Guillen, Zinnia P., Whitaker, Martin J., Ross, Richard J., Kloft, Charlotte

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Mechanistic modelling of enzyme‐restoration effects of new recombinant liver‐targeted proteins in acute intermittent porphyria von Vera‐Yunca, Diego, Córdoba, Karol M., Parra‐Guillen, Zinnia P., Jericó, Daniel, Fontanellas, Antonio, Trocóniz, Iñaki F.

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Disease pharmacokinetic–pharmacodynamic modelling in acute intermittent porphyria to support the development of mRNA‐based therapies von Parra‐Guillen, Zinnia P., Fontanellas, Antonio, Jiang, Lei, Jericó, Daniel, Martini, Paolo, Vera‐Yunca, Diego, Hard, Marjie, Guey, Lin T., Troconiz, Iñaki F.

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Response to ‘Hydrocortisone suspension formulations are not necessarily the same in the treatment of children with congenital adrenal hyperplasia’ von Michelet, Robin, Melin, Johanna, Parra‐Guillen, Zinnia P, Neumann, Uta, Whitaker, Martin J, Stachanow, Viktoria, Huisinga, Wilhelm, Porter, John, Blankenstein, Oliver, Ross, Richard J, Kloft, Charlotte

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Disentangling Anti‐Tumor Response of Immunotherapy Combinations: A Physiologically Based Framework for V937 Oncolytic Virus and Pembrolizumab von Sancho‐Araiz, Aymara, Parra‐Guillen, Zinnia P., Troconiz, Iñaki F., Freshwater, Tomoko

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Gene Therapy: A Pharmacokinetic/Pharmacodynamic Modelling Overview von Parra-Guillén, Zinnia P, González-Aseguinolaza, Gloria, Berraondo, Pedro, Trocóniz, Iñaki F

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Relevance of primary lesion location, tumour heterogeneity and genetic mutation demonstrated through tumour growth inhibition and overall survival modelling in metastatic colorecta... von Vera‐Yunca, Diego, Parra‐Guillen, Zinnia P., Girard, Pascal, Trocóniz, Iñaki F., Terranova, Nadia

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The fusion protein of IFN-α and apolipoprotein A-I crosses the blood-brain barrier by a saturable transport mechanism von Fioravanti, Jessica, Medina-Echeverz, José, Ardaiz, Nuria, Gomar, Celia, Parra-Guillén, Zinnia P, Prieto, Jesús, Berraondo, Pedro

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Assessment of Clinical Response to V937 Oncolytic Virus After Intravenous or Intratumoral Administration Using Physiologically‐Based Modeling von Parra‐Guillen, Zinnia P., Sancho‐Araiz, Aymara, Mayawala, Kapil, Zalba, Sara, Garrido, Maria J., Alwis, Dinesh, Troconiz, Iñaki F., Freshwater, Tomoko

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Model‐Informed Dose Selection for Xentuzumab, a Dual Insulin‐Like Growth Factor‐I/II—Neutralizing Antibody von Parra‐Guillen, Zinnia P., Schmid, Ulrike, Janda, Alvaro, Freiwald, Matthias, Troconiz, Iñaki F.

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Editorial: Innovative pharmacometric approaches to inform drug development and clinical use von Garcia-Cremades, Maria, Parra-Guillen, Zinnia P., Mangas-Sanjuan, Victor, Geerts, Hugo

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Mechanistic characterization of oscillatory patterns in unperturbed tumor growth dynamics: The interplay between cancer cells and components of tumor microenvironment von Sancho-Araiz, Aymara, Parra-Guillen, Zinnia P, Bragard, Jean, Ardanza, Sergio, Mangas-Sanjuan, Victor, Trocóniz, Iñaki F

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Population pharmacokinetics of sublingually administered tacrolimus in infants and young children with liver transplantation von Riva, Natalia, Ibarra, Manuel, Parra‐Guillen, Zinnia P., Galván, Maria Eugenia, Pérez, Erika, Trezeguet Renatti, Guido, Cáceres Guido, Paulo, Lopez, Clarisa, Licciardone, Nieves, Halac, Esteban, Dip, Marcelo, Cruz, Alejandro, Imventarza, Oscar, Buamscha, Daniel, Troconiz, Iñaki F., Schaiquevich, Paula

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A physiologically based pharmacokinetic model for V937 oncolytic virus in mice von Peribañez-Dominguez, Sara, Parra-Guillen, Zinnia P., Freshwater, Tomoko, Troconiz, Iñaki F.

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Mechanistic Modeling of a Novel Oncolytic Virus, V937, to Describe Viral Kinetic and Dynamic Processes Following Intratumoral and Intravenous Administration von Parra-Guillen, Zinnia P., Freshwater, Tomoko, Cao, Youfang, Mayawala, Kapil, Zalba, Sara, Garrido, Maria J., de Alwis, Dinesh, Troconiz, Iñaki F.

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Computational disease model of phenobarbital-induced acute attacks in an acute intermittent porphyria mouse model von Vera-Yunca, Diego, Serrano-Mendioroz, Irantzu, Sampedro, Ana, Jericó, Daniel, Trocóniz, Iñaki F., Fontanellas, Antonio, Parra-Guillén, Zinnia P.

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Role of Cytochrome P450 3A4 and 1A2 Phenotyping in Patients with Advanced Non‐small‐Cell Lung Cancer Receiving Erlotinib Treatment von Parra‐Guillen, Zinnia P., Berger, Peter B., Haschke, Manuel, Donzelli, Massimiliano, Winogradova, Daria, Pfister, Bogumila, Früh, Martin, Gillessen, Silke, Krähenbühl, Stephan, Kloft, Charlotte, Joerger, Markus

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Pharmacokinetic/Pharmacodynamic Evaluation of Hydrocortisone Therapy in Pediatric Patients with Congenital Adrenal Hyperplasia von Melin, Johanna, Parra-Guillen, Zinnia P, Michelet, Robin, Truong, Thi, Huisinga, Wilhelm, Hartung, Niklas, Hindmarsh, Peter, Kloft, Charlotte

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A quantitative systems pharmacology model for acute viral hepatitis B von Asín-Prieto, Eduardo, Parra-Guillen, Zinnia P., Gómez Mantilla, José David, Vandenbossche, Joris, Stuyckens, Kim, de Trixhe, Xavier Woot, Perez-Ruixo, Juan José, Troconiz, Iñaki F.

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