Rhodium-Catalyzed Conversion of Furans to Highly Functionalized Pyrroles von Parr, Brendan T, Green, Samantha A, Davies, Huw M. L

Volltext

A concise synthesis of (+)-batzelladine B from simple pyrrole-based starting materials von Parr, Brendan T., Economou, Christos, Herzon, Seth B.

Volltext

Highly Stereoselective C–C Bond Formation by Rhodium-Catalyzed Tandem Ylide Formation/[2,3]-Sigmatropic Rearrangement between Donor/Acceptor Carbenoids and Chiral Allylic Alcohols... von Li, Zhanjie, Parr, Brendan T., Davies, Huw M. L.

Volltext

Rhodium-Catalyzed Tandem Cyclopropanation/Cope Rearrangement of 4-Alkenyl-1-sulfonyl-1,2,3-triazoles with Dienes von Parr, Brendan T., Davies, Huw M. L.

Volltext

Highly stereoselective synthesis of cyclopentanes bearing four stereocentres by a rhodium carbene-initiated domino sequence von Parr, Brendan T, Davies, Huw M.L.

Volltext

Enyne Amides to Fused Pyridones: Scope and Limitations von Labadie, Sharada S., Thai, Karine, Grandner, Jessica M., Liu, Yanzhou, Parr, Brendan T.

Volltext

Rhodium(II)-Catalyzed Cross-Coupling of Diazo Compounds von Hansen, Jørn H, Parr, Brendan T, Pelphrey, Philip, Jin, Quihui, Autschbach, Jochen, Davies, Huw M.L

Volltext

A convergent approach to batzelladine alkaloids. Total syntheses of (+)-batzelladine E, (−)-dehydrobatzelladine C, and (+)-batzelladine K von Economou, Christos, Romaire, Justin P., Scott, Tony Z., Parr, Brendan T., Herzon, Seth B.

Volltext

Unearthing the Subtleties of Rhodium(II)-Catalyzed Carbenoid Cycloadditions to Furans with an N‑Sulfonyl-1,2,3-triazole Probe von Bettencourt, Christian J., Krainz, Tanja, Chow, Sharon, Parr, Brendan T., Tracy, William F., Bernhardt, Paul V., Davies, Huw M. L., Williams, Craig M.

Volltext

Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5‑Fluoro-4-(3H)‑quinazolinone Aryl Urea pan-RAF Kinase Inhibitor von Huestis, Malcolm P, Dela Cruz, Darlene, DiPasquale, Antonio G, Durk, Matthew R, Eigenbrot, Charles, Gibbons, Paul, Gobbi, Alberto, Hunsaker, Thomas L, La, Hank, Leung, Dennis H, Liu, Wendy, Malek, Shiva, Merchant, Mark, Moffat, John G, Muli, Christine S, Orr, Christine J, Parr, Brendan T, Shanahan, Frances, Sneeringer, Christopher J, Wang, Weiru, Yen, Ivana, Yin, Jianping, Siu, Michael, Rudolph, Joachim

Volltext

Stereoselective Synthesis of Highly Substituted Cyclohexanes by a Rhodium-Carbene Initiated Domino Sequence von Parr, Brendan T, Davies, Huw M. L

Volltext

Asymmetric Synthesis of Highly Functionalized Cyclopentanes by a Rhodium- and Scandium-Catalyzed Five-Step Domino Sequence von Parr, Brendan T, Li, Zhanjie, Davies, Huw M L

Volltext

Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors von Parr, Brendan T, Pastor, Richard, Sellers, Benjamin D, Pei, Zhonghua, Jaipuri, Firoz A, Castanedo, Georgette M, Gazzard, Lewis, Kumar, Sanjeev, Li, Xiaokai, Liu, Wen, Mendonca, Rohan, Pavana, Roheeth K, Potturi, Hima, Shao, Cheng, Velvadapu, Venkata, Waldo, Jesse P, Wu, Guosheng, Yuen, Po-wai, Zhang, Zuhui, Zhang, Yamin, Harris, Seth F, Oh, Angela J, DiPasquale, Antonio, Dement, Kevin, La, Hank, Goon, Leanne, Gustafson, Amy, VanderPorten, Erica C, Mautino, Mario R, Liu, Yichin

Volltext

Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2) von Zeng, Mingshuo, Grandner, Jessica M., Bryan, Marian C., Verma, Vishal, Larouche-Gauthier, Robin, Leclerc, Jean-Philippe, Zhao, Liang, Haghshenas, Pouyan, Aubert-Nicol, Samuel, Yadav, Arun, Ashley, Melissa, Chen, Jacob Z., Durk, Matthew, Samy, Karen E., Nespi, Marika, Levy, Elizabeth, Merrick, Karl, Moffat, John G., Murray, Jeremy, Oh, Angela, Orr, Christine, Segal, Ehud, Sims, Jessica, Sneeringer, Christopher, Prangley, Madeleine, Vartanian, Steffan, Magnuson, Steven, Parr, Brendan T.

Volltext

Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor von Huestis, Malcolm P, Durk, Matthew R, Eigenbrot, Charles, Gibbons, Paul, Hunsaker, Thomas L, La, Hank, Leung, Dennis H, Liu, Wendy, Malek, Shiva, Merchant, Mark, Moffat, John G, Muli, Christine S, Orr, Christine J, Parr, Brendan T, Shanahan, Frances, Sneeringer, Christopher J, Wang, Weiru, Yen, Ivana, Yin, Jianping, Rudolph, Joachim, Siu, Michael

Volltext

Michael−Aldol Ring Closures with Dihapto-Coordinated Pyrrole Complexes and the Synthesis of Tetrahydroindole Cores von Welch, Kevin D, Harrison, Daniel P, Sabat, Michal, Hejazi, Emily Z, Parr, Brendan T, Fanelli, Matthew G, Gianfrancesco, Nicole A, Nagra, Dalsher S, Myers, William H, Harman, W. Dean

Volltext

Evaluating methods to create protein functionalized catanionic vesicles von Zayka, Paul, Parr, Brendan, Robichaud, Hannah, Hickey, Skyler, Topping, Amber, Holt, Elizabeth, Watts, David B. E, Soto, Nicholas, Stein, Daniel C, DeShong, Philip, Hurley, Matthew

Volltext

Rhodium‐Catalyzed Tandem Cyclopropanation/Cope Rearrangement of 4‐Alkenyl‐1‐sulfonyl‐1,2,3‐triazoles with Dienes von Parr, Brendan T., Davies, Huw M. L.

Volltext

TPL2 kinase action and control of inflammation von Xu, Daqi, Kwon, Youngsu, Senger, Kate, Pham, Victoria, Varfolomeev, Eugene, Francis, George, Hackney, Jason, Parr, Brendan, Rathore, Nisha, Setiadi, Francesca, Boenig, Gladys, Harris, Seth, Lupardus, Patrick, Matsumoto, Marissa, Wang, Yuanyuan, Hanson, Jesse, Maher, Jonathan, Wu, Kai, Shaw, Andrey, Scherl, Alexis, Wu, Jiansheng, Lu, Cheng, Huang, Zhiyu, Zhang, Juan, Park, Summer, Sujatha-Bhaskar, Swathi, Almazan, Alice, Xu, Min, Caplazi, Patrick, Brightbill, Hans, Ghilardi, Nico, Townsend, Michael, Lee, Wyne, Johnson, Adam, McKenzie, Brent, Zarrin, Ali A, Wilson, Mark

Volltext

Asymmetric synthesis of highly functionalized cyclopentanes by a rhodium- and scandium-catalyzed five-step domino sequenceElectronic supplementary information (ESI) available: Full... von Parr, Brendan T, Li, Zhanjie, Davies, Huw M. L

Volltext