Chronic treatment with a glucagon receptor antagonist lowers glucose and moderately raises circulating glucagon and glucagon-like peptide 1 without severe alpha cell hypertrophy in... von Mu, J., Jiang, G., Brady, E., Dallas-Yang, Q., Liu, F., Woods, J., Zycband, E., Wright, M., Li, Z., Lu, K., Zhu, L., Shen, X., SinhaRoy, R., Candelore, M. L., Qureshi, S. A., Shen, D-M., Zhang, F., Parmee, E. R., Zhang, B. B.

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New catalysts for the asymmetric aldol reaction: chiral boranes prepared from .alpha.,.alpha.-disubstituted glycine arenesulfonamides von Parmee, Emma R, Tempkin, Orin, Masamune, Satoru, Abiko, Atsushi

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Crystal Structure of Human Phosphodiesterase 3B:  Atomic Basis for Substrate and Inhibitor Specificity von Scapin, Giovanna, Patel, Sangita B, Chung, Christine, Varnerin, Jeffrey P, Edmondson, Scott D, Mastracchio, Anthony, Parmee, Emma R, Singh, Suresh B, Becker, Joseph W, Van der Ploeg, Lex H. T, Tota, Michael R

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Palladium-Catalyzed Coupling of Vinylogous Amides with Aryl Halides:  Applications to the Synthesis of Heterocycles von Edmondson, Scott D, Mastracchio, Anthony, Parmee, Emma R

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Substituted piperazines as novel dipeptidyl peptidase IV inhibitors von Brockunier, Linda L., He, Jiafang, Colwell, Lawrence F., Habulihaz, Bahanu, He, Huaibing, Leiting, Barbara, Lyons, Kathryn A., Marsilio, Frank, Patel, Reshma A., Teffera, Yohannes, Wu, Joseph K., Thornberry, Nancy A., Weber, Ann E., Parmee, Emma R.

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Human β 3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides von Brockunier, Linda L, Parmee, Emma R, Ok, Hyun O, Candelore, Mari R, Cascieri, Margaret A, Colwell, Lawrence F, Deng, Liping, Feeney, William P, Forrest, Michael J, Hom, Gary J, MacIntyre, D.Euan, Tota, Laurie, Wyvratt, Matthew J, Fisher, Michael H, Weber, Ann E

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Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors von CALDWELL, Charles G, PING CHEN, HUAIBING HE, LYONS, Kathryn A, THORNBERRY, Nancy A, WEBER, Ann E, JIAFANG HE, PARMEE, Emma R, LEITING, Barbara, MARSILIO, Frank, PATEL, Reshma A, WU, Joseph K, EIERMANN, George J, PETROV, Aleksandr

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A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys von Fisher, M H, Amend, A M, Bach, T J, Barker, J M, Brady, E J, Candelore, M R, Carroll, D, Cascieri, M A, Chiu, S H, Deng, L, Forrest, M J, Hegarty-Friscino, B, Guan, X M, Hom, G J, Hutchins, J E, Kelly, L J, Mathvink, R J, Metzger, J M, Miller, R R, Ok, H O, Parmee, E R, Saperstein, R, Strader, C D, Stearns, R A, MacIntyre, D E

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Potent and selective proline derived dipeptidyl peptidase IV inhibitors von Edmondson, Scott D., Mastracchio, Anthony, Beconi, Maria, Colwell, Lawrence F., Habulihaz, Bahanu, He, Huaibing, Kumar, Sanjeev, Leiting, Barbara, Lyons, Kathryn A., Mao, Ann, Marsilio, Frank, Patel, Reshma A., Wu, Joseph K., Zhu, Lan, Thornberry, Nancy A., Weber, Ann E., Parmee, Emma R.

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Discovery of potent and selective β-homophenylalanine based dipeptidyl peptidase IV inhibitors von Xu, Jinyou, Ok, Hyun O., Gonzalez, Edward J., Colwell, Lawrence F., Habulihaz, Bahanu, He, Huaibing, Leiting, Barbara, Lyons, Kathryn A., Marsilio, Frank, Patel, Reshma A., Wu, Joseph K., Thornberry, Nancy A., Weber, Ann E., Parmee, Emma R.

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Total synthesis of milbemycins: a synthesis of (6R)-6-hydroxy-3,4-dihydromilbemycin E von Helliwell, Madeleine, Karim, Sufia, Parmee, Emma R, Thomas, Eric J

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Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonists von Shen, Dong-Ming, Zhang, Fengqi, Brady, Edward J., Candelore, Mari Rios, Dallas-Yang, Qing, Ding, Victor D.-H., Dragovic, Jasminka, Feeney, William P., Jiang, Guoquiang, McCann, Peggy E., Mock, Steve, Qureshi, Sajjad A., Saperstein, Richard, Shen, Xiaolan, Tamvakopoulos, Constantin, Tong, Xinchun, Tota, Laurie M., Wright, Michael J., Yang, Xiaodong, Zheng, Song, Chapman, Kevin T., Zhang, Bei B., Tata, James R., Parmee, Emma R.

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4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors von Parmee, Emma R., He, Jiafang, Mastracchio, Anthony, Edmondson, Scott D., Colwell, Larry, Eiermann, George, Feeney, William P., Habulihaz, Bahanu, He, Huaibing, Kilburn, Ruth, Leiting, Barbara, Lyons, Kathryn, Marsilio, Frank, Patel, Reshma A., Petrov, Aleksandr, Di Salvo, Jerry, Wu, Joseph K., Thornberry, Nancy A., Weber, Ann E.

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Milbemycin synthesis: synthesis of 6β-hydroxy-3,4-dihydromilbemycin E von Karim, Sufia, Parmee, Emma R., Thomas, Eric J.

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Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors von Edmondson, Scott D., Mastracchio, Anthony, He, Jiafang, Chung, Christine C., Forrest, Michael J., Hofsess, Scott, MacIntyre, Euan, Metzger, Joseph, O'Connor, Naphtali, Patel, Kajal, Tong, Xinchun, Tota, Michael R., Van der Ploeg, Lex H.T., Varnerin, Jeff P., Fisher, Michael H., Wyvratt, Matthew J., Weber, Ann E., Parmee, Emma R.

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Direct observation (NMR) of the efficacy of glucagon receptor antagonists in murine liver expressing the human glucagon receptor von Cohen, Sheila M., Duffy, Joseph L., Miller, Corin, Kirk, Brian A., Candelore, Mari Rios, Ding, Victor D.H., Kaczorowski, Gregory, Tota, Laurie M., Werrmann, Jeffrey G., Wright, Michael, Parmee, Emma R., Tata, James R., Zhang, Bei B.

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Discovery of L-755,507: A subnanomolar human β3 adrenergic receptor agonist von Parmee, Emma R., Ok, Hyun O., Candelore, Mari R., Tota, Laurie, Deng, Liping, Strader, Catherine D., Wyvratt, Matthew J., Fisher, Michael H., Weber, Ann E.

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A total synthesis of milbemycin E von PARMEE, E. R, STEEL, P. G, THOMAS, E. J

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Human β3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides von NAYLOR, E. M, PARMEE, E. R, FORREST, M. J, HOM, G. J, MACINTYRE, D. E, STRADER, C. D, TOTA, L, WANG, P.-R, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, COLANDREA, V. J, PERKINS, L, BROCKUNIER, L, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F, LIPING DENG, FEENEY, W. P

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Crystallization and preliminary X-ray diffraction analysis of the catalytic domain of recombinant human phosphodiesterase 3B von Patel, Sangita B., Varnerin, Jeffrey P., Tota, Michael R., Edmondson, Scott D., Parmee, Emma R., Becker, Joseph W., Scapin, Giovanna

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