[18F](R)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4-(2-fluoroethoxy)-2,5-dimethyl phenylamino)pyrazin-2(1H)-one: Introduction of N3-phenylpyrazinones as potential CRF-R1 PET im... von Deskus, Jeffrey A., Dischino, Douglas D., Mattson, Ronald J., Ditta, Jonathan L., Parker, Michael F., Denhart, Derek J., Zuev, Dmitry, Huang, Hong, Hartz, Richard A., Ahuja, Vijay T., Wong, Henry, Mattson, Gail K., Molski, Thaddeus F., Grace, James E., Zueva, Larisa, Nielsen, Julia M., Dulac, Heidi, Li, Yu-Wen, Guaraldi, Mary, Azure, Michael, Onthank, David, Hayes, Megan, Wexler, Eric, McDonald, Jennifer, Lodge, Nicholas J., Bronson, Joanne J., Macor, John E.

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Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor von Gillman, Kevin W, Starrett, John E, Parker, Michael F, Xie, Kai, Bronson, Joanne J, Marcin, Lawrence R, McElhone, Kate E, Bergstrom, Carl P, Mate, Robert A, Williams, Richard, Meredith, Jere E, Burton, Catherine R, Barten, Donna M, Toyn, Jeremy H, Roberts, Susan B, Lentz, Kimberley A, Houston, John G, Zaczek, Robert, Albright, Charles F, Decicco, Carl P, Macor, John E, Olson, Richard E

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Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1 von Marcin, Lawrence R., Higgins, Mendi A., Zusi, F. Christopher, Zhang, Yunhui, Dee, Michael F., Parker, Michael F., Muckelbauer, Jodi K., Camac, Daniel M., Morin, Paul E., Ramamurthy, Vidhyashankar, Tebben, Andrew J., Lentz, Kimberley A., Grace, James E., Marcinkeviciene, Jovita A., Kopcho, Lisa M., Burton, Catherine R., Barten, Donna M., Toyn, Jeremy H., Meredith, Jere E., Albright, Charles F., Bronson, Joanne J., Macor, John E., Thompson, Lorin A.

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NK1 receptor antagonism lowers occupancy requirement for antidepressant-like effects of SSRIs in the Gerbil forced swim test von Lelas, Snjezana, Li, Yu-Wen, Wallace-Boone, Tanya L., Taber, Matthew T., Newton, Amy E., Pieschl, Rick L., Davis, Carl D., Molski, Thaddeus F., Newberry, Kimberly S., Parker, Michael F., Gillman, Kevin W., Bronson, Joanne J., Macor, John E., Lodge, Nicholas J.

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Chronobiotic activity of N-[2-(2,7-dimethoxyfluoren-9-yl)ethyl]-propanamide. Synthesis and melatonergic pharmacology of fluoren-9-ylethyl amides von Epperson, James R., Bruce, Marc A., Catt, John D., Deskus, Jeffrey A., Hodges, Donald B., Karageorge, George N., Keavy, Daniel J., Mahle, Cathy D., Mattson, Ronald J., Ortiz, Astrid A., Parker, Michael F., Takaki, Katherine S., Watson, Brett T., Joseph P.Yevich

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Design, optimization, and in vivo evaluation of a series of pyridine derivatives with dual NK1 antagonism and SERT inhibition for the treatment of depression von Gillman, Kevin W., Parker, Michael F., Silva, Mark, Degnan, Andrew P., Tora, George O., Lodge, Nicholas J., Li, Yu-Wen, Lelas, Snjezana, Taber, Matthew, Krause, Rudolf G., Bertekap, Robert L., Newton, Amy E., Pieschl, Rick L., Lengyel, Kelly D., Johnson, Kim A., Taylor, Sarah J., Bronson, Joanne J., Macor, John E.

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2-(N-Benzyl-N-phenylsulfonamido)alkyl amide derivatives as γ-secretase inhibitors von Parker, Michael F., Barten, Donna M., Bergstrom, Carl P., Bronson, Joanne J., Corsa, Jason A., Dee, Michael F., Gai, Yonghua, Guss, Valerie L., Higgins, Mendi A., Keavy, Daniel J., Loo, Alice, Mate, Robert A., Marcin, Larry R., McElhone, Katharine E., Polson, Craig T., Roberts, Susan B., Macor, John E.

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Amino-caprolactam derivatives as γ-secretase inhibitors von Parker, Michael F., Bronson, Joanne J., Barten, Donna M., Corsa, Jason A., Du, Wengsheng, Felsenstein, Kevin M., Guss, Valerie L., Izzarelli, Darcy, Loo, Alice, McElhone, Kate E., Marcin, Larry R., Padmanabha, Ramesh, Pak, Roger, Polson, Craig T., Toyn, Jeremy H., Varma, Sam, Wang, Jian, Wong, Victoria, Zheng, Ming, Roberts, Susan B.

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Nitrogen-appended N-alkylsulfonamides as inhibitors of γ-secretase von Bergstrom, Carl P., Sloan, Charles P., Wang, Henry H., Parker, Michael F., Smith, David W., Zheng, Ming, Hansel, Steven B., Polson, Craig T., Barber, Lauren E., Bursuker, Isia, Guss, Valerie L., Corsa, Jason A., Barten, Donna M., Felsenstein, Kevin M., Roberts, Susan B.

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N-(5-Chloro-2-(hydroxymethyl)-N-alkyl-arylsulfonamides as γ-secretase inhibitors von Parker, Michael F., Barten, Donna M., Bergstrom, Carl P., Bronson, Joanne J., Corsa, Jason A., Deshpande, Milind S., Felsenstein, Kevin M., Guss, Valerie L., Hansel, Steven B., Johnson, Graham, Keavy, Daniel J., Lau, Wai Y., Mock, Jeremy, Prasad, C.V.C., Polson, Craig T., Sloan, Charles P., Smith, David W., Wallace, Owen B., Wang, Henry H., Williams, Andrew, Zheng, Ming

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Hydroxytriamides as potent γ-secretase inhibitors von Prasad, C.V.C, Noonan, Jeffrey W, Sloan, Charles P, Lau, Wai, Vig, Shikha, Parker, Michael F, Smith, David W, Hansel, Steven B, Polson, Craig T, Barten, Donna M, Felsenstein, Kevin M, Roberts, Susan B

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Synthesis of radio-iodinated melatonergic agents von Dischino, Douglas D., Mattson, Ronald J., Ogan, Marc D., Parker, Michael F., Yevich, Joseph P.

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KRAS INHIBITORS von PARKER, Michael F, CIVIELLO, Rita Lee, CONDAKES, Matthew Leo, BRONSON, Joanne Jewett

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PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES AS KRAS INHIBITORS von PARKER, Michael F, CIVIELLO, Rita Lee, CONDAKES, Matthew Leo, BRONSON, Joanne Jewett

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N -5 -Chloro -2-(hydroxymethyl)-N -alkyl -arylsulfonamides as γ-secretase inhibitors von PARKER, Michael F, BARTEN, Donna M, KEAVY, Daniel J, LAU, Wai Y, MOCK, Jeremy, PRASAD, C. V. C, POISON, Craig T, SLOAN, Charles P, SMITH, David W, WALLACE, Owen B, WANG, Henry H, WILLIAMS, Andrew, BERGSTROM, Carl P, MING ZHENG, BRONSON, Joanne J, CORSA, Jason A, DESHPANDE, Milind S, FELSENSTEIN, Kevin M, GUSS, Valerie L, HANSEL, Steven B, JOHNSON, Graham

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Direct design of a potent non-peptide fibrinogen receptor antagonist based on the structure and conformation of a highly constrained cyclic RGD peptide von Ku, Thomas W, Ali, Fadia E, Barton, Linda S, Bean, John W, Bondinell, William E, Burgess, Joelle L, Callahan, James F, Calvo, Raul R, Chen, Lichong

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BICYCLIC INHIBITORS OF PAD4 von KERRY, Philip, COOPER, Sophie, LOKE, Pui, GADOULEAU, Elise, KUMARAVEL, Gnanasambandam, KRULLE, Thomas, TYE, Heather, MONCK, Nat, NORTH, Carl, DEVRAJ, Rajesh, PARKER, Michael F, KOTEY, Adrian, RIDGILL, Mark, BEAUMONT, Edward, MENICONI, Mirco, BOWLES, Lee, PARROTT, Shelley, PALFREY, Jordan, BROMBRIDGE, Steve, GLEAVE, Laura, LECCI, Cristina

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3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS von SELVAKUMAR, Kumaravel, DEVASTHALE, Pratik, HAN, Xiaojun, PARKER, Michael F, BALASUBRAMANIAN, Palanikumar, GUERNON, Leatte R, YE, Xiang-Yang, CIVIELLO, Rita, DHANUSU, Suresh, JACUTIN-PORTE, Swanee E, ZHAO, Guohua

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Corrigendum to “Hydroxytriamides as potent γ-secretase inhibitors”: [Bioorg. Med. Chem. Lett. 14 (2004) 1917] von Prasad, C.V.C., Wallace, Owen B., Noonan, Jeffrey W., Sloan, Charles P., Lau, Wai, Vig, Shikha, Parker, Michael F., Smith, David W., Hansel, Steven B., Polson, Craig T., Barten, Donna M., Felsenstein, Kevin M., Roberts, Susan B.

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3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS von Zhao, Guohua, Selvakumar, Kumaravel, Ye, Xiang-yang, Parker, Michael F, Dhanusu, Suresh, Balasubramanian, Palanikumar, Han, Xiaojun, Jacutin-porte, Swanee E, Devasthale, Pratik, Guernon, Leatte R, Civiello, Rita

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