Azole fungicides – understanding resistance mechanisms in agricultural fungal pathogens von Price, Claire L, Parker, Josie E, Warrilow, Andrew GS, Kelly, Diane E, Kelly, Steven L

Volltext

ERG6 and ERG2 Are Major Targets Conferring Reduced Susceptibility to Amphotericin B in Clinical Candida glabrata Isolates in Kuwait von Ahmad, Suhail, Joseph, Leena, Parker, Josie E, Asadzadeh, Mohammad, Kelly, Steven L, Meis, Jacques F, Khan, Ziauddin

Volltext

The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus von Furukawa, Takanori, van Rhijn, Norman, Fraczek, Marcin, Gsaller, Fabio, Davies, Emma, Carr, Paul, Gago, Sara, Fortune-Grant, Rachael, Rahman, Sayema, Gilsenan, Jane Mabey, Houlder, Emma, Kowalski, Caitlin H., Raj, Shriya, Paul, Sanjoy, Cook, Peter, Parker, Josie E., Kelly, Steve, Cramer, Robert A., Latgé, Jean-Paul, Moye-Rowley, Scott, Bignell, Elaine, Bowyer, Paul, Bromley, Michael J.

Volltext

Azole Affinity of Sterol 14α-Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens von WARRILOW, Andrew G, PARKER, Josie E, KELLY, Diane E, KELLY, Steven L

Volltext

Cytochrome P450 168A1 from Pseudomonas aeruginosa is involved in the hydroxylation of biologically relevant fatty acids von Price, Claire L, Warrilow, Andrew G S, Rolley, Nicola J, Parker, Josie E, Thoss, Vera, Kelly, Diane E, Corcionivoschi, Nicolae, Kelly, Steven L

Volltext

Mutations in hmg1 , Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus von Rybak, Jeffrey M, Ge, Wenbo, Wiederhold, Nathan P, Parker, Josie E, Kelly, Steven L, Rogers, P David, Fortwendel, Jarrod R

Volltext

Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function von Fan, Jieru, Urban, Martin, Parker, Josie E., Brewer, Helen C., Kelly, Steven L., Hammond‐Kosack, Kim E., Fraaije, Bart A., Liu, Xili, Cools, Hans J.

Volltext

The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species von Xie, Jinhong, Rybak, Jeffrey M., Martin-Vicente, Adela, Guruceaga, Xabier, Thorn, Harrison I., Nywening, Ashley V., Ge, Wenbo, Parker, Josie E., Kelly, Steven L., Rogers, P. David, Fortwendel, Jarrod R.

Volltext

In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection von Colley, Thomas, Alanio, Alexandre, Kelly, Steven L, Sehra, Gurpreet, Kizawa, Yasuo, Warrilow, Andrew G S, Parker, Josie E, Kelly, Diane E, Kimura, Genki, Anderson-Dring, Lauren, Nakaoki, Takahiro, Sunose, Mihiro, Onions, Stuart, Crepin, Damien, Lagasse, Franz, Crittall, Matthew, Shannon, Jonathan, Cooke, Michael, Bretagne, Stéphane, King-Underwood, John, Murray, John, Ito, Kazuhiro, Strong, Pete, Rapeport, Garth

Volltext

In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris von Rybak, Jeffrey M., Barker, Katherine S., Muñoz, José F., Parker, Josie E., Ahmad, Suhail, Mokaddas, Eiman, Abdullah, Aneesa, Elhagracy, Rehab S., Kelly, Steve L., Cuomo, Christina A., Rogers, P. David

Volltext

Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris von Rybak, Jeffrey M., Munoz, Jose F., Barker, Katherine S., Parker, Josie E., Esquivel, Brooke D., Berkow, Elizabeth L., Lockhart, Shawn R., Gade, Lalitha, Palmer, Glen E., White, Theodore C., Kelly, Steve L., Cuomo, Christina A., Rogers, P. David

Volltext

Azole Affinity of Sterol 14?-Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens von Warrilow, Andrew G, Parker, Josie E, Kelly, Diane E, Kelly, Steven L

Volltext

Molecular Mechanisms of Drug Resistance in Clinical Candida Species Isolated from Tunisian Hospitals von EDDOUZI, Jamel, PARKER, Josie E, VALE-SILVA, Luis A, COSTE, Alix, ISCHER, Françoise, KELLY, Steve, MANAI, Mohamed, SANGLARD, Dominique

Volltext

Species-Specific Differences in C-5 Sterol Desaturase Function Influence the Outcome of Azole Antifungal Exposure von Luna-Tapia, Arturo, Parker, Josie E., Kelly, Steven L., Palmer, Glen E.

Volltext

Multidrug Transporters and Alterations in Sterol Biosynthesis Contribute to Azole Antifungal Resistance in Candida parapsilosis von Berkow, Elizabeth L, Manigaba, Kayihura, Parker, Josie E, Barker, Katherine S, Kelly, Stephen L, Rogers, P David

Volltext

A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1 von Rybak, Jeffrey M., Xie, Jinhong, Martin-Vicente, Adela, Guruceaga, Xabier, Thorn, Harrison I., Nywening, Ashley V., Ge, Wenbo, Souza, Ana C. O., Shetty, Amol C., McCracken, Carrie, Bruno, Vincent M., Parker, Josie E., Kelly, Steven L., Snell, Hannah M., Cuomo, Christina A., Rogers, P. David, Fortwendel, Jarrod R.

Volltext

Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Ampho... von HULL, Claire M, PARKER, Josie E, BADER, Oliver, WEIG, Michael, GROSS, Uwe, WARRILOW, Andrew G. S, KELLY, Diane E, KELLY, Steven L

Volltext

Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis von Morgan, Siân R., Pilia, Nicole, Hewitt, Melissa, Moses, Rachael L., Moseley, Ryan, Lewis, Philip N., Morrison, Peter W.J., Kelly, Steven L., Parker, Josie E., Whitaker, David, Quantock, Andrew J., Heard, Charles M.

Volltext

Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola von Mullins, Jonathan G L, Parker, Josie E, Cools, Hans J, Togawa, Roberto C, Lucas, John A, Fraaije, Bart A, Kelly, Diane E, Kelly, Steven L

Volltext

Comparative Genomics for the Elucidation of Multidrug Resistance in Candida lusitaniae von Kannan, Abhilash, Asner, Sandra A, Trachsel, Emilie, Kelly, Steve, Parker, Josie, Sanglard, Dominique

Volltext