Preclinical Development of a Hematopoietic Stem and Progenitor Cell Bioengineered Factor VIII Lentiviral Vector Gene Therapy for Hemophilia A von Doering, Christopher B, Denning, Gabriela, Shields, Jordan E, Fine, Eli J, Parker, Ernest T, Srivastava, Alok, Lollar, Pete, Spencer, H Trent

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Frequency and epitope specificity of anti–factor VIII C1 domain antibodies in acquired and congenital hemophilia A von Kahle, Joerg, Orlowski, Aleksander, Stichel, Diana, Healey, John F., Parker, Ernest T., Jacquemin, Marc, Krause, Manuela, Tiede, Andreas, Schwabe, Dirk, Lollar, Pete, Königs, Christoph

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The diversity of the immune response to the A2 domain of human factor VIII von Markovitz, Rebecca C., Healey, John F., Parker, Ernest T., Meeks, Shannon L., Lollar, Pete

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Conformation of the von Willebrand factor/factor VIII complex in quasi-static flow von Parker, Ernest T., Lollar, Pete

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Neutralizing Antibodies Against Factor VIII Can Occur Through a Non-Germinal Center Pathway von Patel, Seema R, Lundgren, Taran S, Baldwin, Wallace Hunter, Cox, Courtney, Parker, Ernest T, Healey, John F, Jajosky, Ryan P, Zerra, Patricia E, Josephson, Cassandra D, Doering, Christopher B, Stowell, Sean R, Meeks, Shannon L

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Antihuman factor VIII C2 domain antibodies in hemophilia A mice recognize a functionally complex continuous spectrum of epitopes dominated by inhibitors of factor VIII activation von Meeks, Shannon L., Healey, John F., Parker, Ernest T., Barrow, Rachel T., Lollar, Pete

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Target-Cell-Directed Bioengineering Approaches for Gene Therapy of Hemophilia A von Brown, Harrison C, Zakas, Philip M, George, Stephan N, Parker, Ernest T, Spencer, H Trent, Doering, Christopher B

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Engineering a Therapeutic Protein to Enhance the Study of Anti-Drug Immunity von Zerra, Patricia E., Parker, Ernest T., Baldwin, Wallace Hunter, Healey, John F., Patel, Seema R., McCoy, James W., Cox, Courtney, Stowell, Sean R., Meeks, Shannon L.

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High-level expression of porcine factor VIII from genetically modified bone marrow–derived stem cells von Gangadharan, Bagirath, Parker, Ernest T., Ide, Lucienne M., Spencer, H. Trent, Doering, Christopher B.

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Factor VIII A3 domain substitution N1922S results in hemophilia A due to domain-specific misfolding and hyposecretion of functional protein von Summers, Ryan J., Meeks, Shannon L., Healey, John F., Brown, Harrison C., Parker, Ernest T., Kempton, Christine L., Doering, Christopher B., Lollar, Pete

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The comparative immunogenicity of human and porcine factor VIII in haemophilia A mice von Healey, John F., Parker, Ernest T., Barrow, Rachel T., Langley, Travis J., Church, William R., Lollar, Pete

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Type 2B von Willebrand disease mutations differentially perturb autoinhibition of the A1 domain von Legan, Emily R., Liu, Yi, Arce, Nicholas A., Parker, Ernest T., Lollar, Pete, Zhang, X. Frank, Li, Renhao

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Nanobody activator improves sensitivity of the von Willebrand factor activity assay to multimer size von Liang, Qian, Parker, Ernest T., Dean, Gabrielle, Karpen, Matthew S., Wu, Yujia, Wang, Xuefeng, Di Paola, Jorge, Maier, Cheryl L., Meeks, Shannon L., Lollar, Pete, Sidonio, Robert F., Li, Renhao

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Removal of single‐site N‐linked glycans on factor VIII alters binding of domain‐specific monoclonal antibodies von Ito, Jasmine, Baldwin, Wallace Hunter, Cox, Courtney, Healey, John F., Parker, Ernest T., Legan, Emily R., Li, Renhao, Gill, Surinder, Batsuli, Glaivy

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Identification of Porcine Coagulation Factor VIII Domains Responsible for High Level Expression via Enhanced Secretion von Doering, Christopher B., Healey, John F., Parker, Ernest T., Barrow, Rachel T., Lollar, Pete

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High Level Expression of Recombinant Porcine Coagulation Factor VIII von Doering, Christopher B., Healey, John F., Parker, Ernest T., Barrow, Rachel T., Lollar, Pete

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Measurement of the Translational Diffusion Coefficient and Hydrodynamic Radius of Proteins by Dynamic Light Scattering von Parker, Ernest T, Lollar, Pete

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A1 Subunit-mediated Regulation of Thrombin-activated Factor VIII A2 Subunit Dissociation von Parker, Ernest T., Doering, Christopher B., Lollar, Pete

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pH-dependent conformation of multimeric von Willebrand factor von Smith, Ian W., Parker, Ernest T., Lollar, Pete

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Subunit Flexibility of Multimeric von Willebrand Factor/Factor VIII Complexes von Parker, Ernest T., Haberichter, Sandra L., Lollar, Pete

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