IL-6 Trans-Signaling via STAT3 Directs T Cell Infiltration in Acute Inflammation von McLoughlin, Rachel M., Jenkins, Brendan J., Grail, Dianne, Williams, Anwen S., Fielding, Ceri A., Parker, Clare R., Ernst, Matthias, Topley, Nicholas, Jones, Simon A., Marrack, Philippa

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Loss of CD4+ T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6 Trans Signaling in the Local Maintenance of Th17 Cells von Jones, Gareth W, McLoughlin, Rachel M, Hammond, Victoria J, Parker, Clare R, Williams, John D, Malhotra, Raj, Scheller, Jurgen, Williams, Anwen S, Rose-John, Stefan, Topley, Nicholas, Jones, Simon A

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Loss of T-cell IL-6R expression during inflammation: IL-6 trans-signaling regulates T-cell trafficking and effector characteristics von Jones, Gareth W., McLoughlin, Rachel M., Hammond, Victoria J., Parker, Clare R., Williams, John D., Malhotra, Raj, Scheller, Jürgen, Rose-John, Stefan, Topley, Nicholas, Jones, Simon A.

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121 Differential control of T-cell responses by classical IL-6 receptor signaling and IL-6 trans-signaling von Jones, Gareth W., McLoughlin, Rachel M., Hammond, Victoria J., Parker, Clare R., Williams, John D., Malhotra, Raj, Scheller, Jürgen, Rose-John, Stefan, Topley, Nicholas, Jones, Simon A.

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Abiraterone in “High-” and “Low-risk” Metastatic Hormone-sensitive Prostate Cancer von Hoyle, Alex P., Ali, Adnan, James, Nicholas D., Cook, Adrian, Parker, Christopher C., de Bono, Johann S., Attard, Gerhardt, Chowdhury, Simon, Cross, William R., Dearnaley, David P., Brawley, Christopher D., Gilson, Clare, Ingleby, Fiona, Gillessen, Silke, Aebersold, Daniel M., Jones, Rob J., Matheson, David, Millman, Robin, Mason, Malcolm D., Ritchie, Alastair W.S., Russell, Martin, Douis, Hassan, Parmar, Mahesh K.B., Sydes, Matthew R., Clarke, Noel W.

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Prenatal exome sequencing analysis in fetal structural anomalies detected by ultrasonography (PAGE): a cohort study von Lord, Jenny, McMullan, Dominic J, Eberhardt, Ruth Y, Rinck, Gabriele, Hamilton, Susan J, Quinlan-Jones, Elizabeth, Prigmore, Elena, Carey, Georgina K, Mellis, Rhiannon, Robart, Sarah, Berry, Ian R, Chandler, Kate E, Cilliers, Deirdre, Cresswell, Lara, Edwards, Sandra L, Gardiner, Carol, Henderson, Alex, Holden, Simon T, Homfray, Tessa, Lester, Tracy, Newbury-Ecob, Ruth, Prescott, Katrina, Quarrell, Oliver W, Ramsden, Simon C, Roberts, Eileen, Tapon, Dagmar, Tooley, Madeleine J, Vasudevan, Pradeep C, Weber, Astrid P, Wellesley, Diana G, Westwood, Paul, White, Helen, Parker, Michael, Williams, Denise, Jenkins, Lucy, Scott, Richard H, Kilby, Mark D, Chitty, Lyn S, Hurles, Matthew E, Maher, Eamonn R, Bateman, Mark, Best, Sunayna K, Campbell, Carolyn, Carey, Georgina, Chitty, Lyn S, Cilliers, Deirdre, Cohen, Kelly, Collingwood, Emma, Constantinou, Panayiotis, Cresswell, Lara, Delmege, Catherine, Edwards, Sandra L, Ellis, Richard, Evans, Jerry, Everett, Thomas, Pinto, Clare F, Forrester, Natalie, Fowler, Emma, Gardiner, Carol, Hamilton, Susan, Healey, Karen, Henderson, Alex, Holden, Simon T, Homfray, Tessa, Hudson, Rebecca, Hurles, Matthew E, Jenkins, Lucy, Keelagher, Rebecca, Kilby, Mark D, Lester, Tracey, Lewis, Rebecca, Lord, Jenny, Maher, Eamonn R, Marton, Tamas, McMullan, Dominic J, Mehta, Sarju, Mellis, Rhiannon, Newbury-Ecob, Ruth, Park, Soo-Mi, Parker, Michael, Prescott, Katrina, Prigmore, Elena, Quarrell, Oliver W, Quinlan-Jones, Elizabeth, Ramsden, Simon C, Rinck, Gabriele, Robart, Sarah, Roberts, Eileen, Rowland, Jayne, Steer, James, Tapon, Dagmar, Taylor, Emma J, Tooley, Madeleine J, Vasudevan, Pradeep C, Weber, Astrid P, Wellesley, Diana G, Westwood, Paul, White, Helen, Williams, Denise, Wilson, Elizabeth

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Overdiagnosis of Clostridium difficile Infection in the Molecular Test Era von Polage, Christopher R, Gyorke, Clare E, Kennedy, Michael A, Leslie, Jhansi L, Chin, David L, Wang, Susan, Nguyen, Hien H, Huang, Bin, Tang, Yi-Wei, Lee, Lenora W, Kim, Kyoungmi, Taylor, Sandra, Romano, Patrick S, Panacek, Edward A, Goodell, Parker B, Solnick, Jay V, Cohen, Stuart H

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The Universal Form of Treatment Options (UFTO) as an alternative to Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) orders: a mixed methods evaluation of the effects on clini... von Fritz, Zoë, Malyon, Alexandra, Frankau, Jude M, Parker, Richard A, Cohn, Simon, Laroche, Clare M, Palmer, Chris R, Fuld, Jonathan P

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Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial von Parker, Christopher C, James, Nicholas D, Brawley, Christopher D, Clarke, Noel W, Hoyle, Alex P, Ali, Adnan, Ritchie, Alastair W S, Attard, Gerhardt, Chowdhury, Simon, Cross, William, Dearnaley, David P, Gillessen, Silke, Gilson, Clare, Jones, Robert J, Langley, Ruth E, Malik, Zafar I, Mason, Malcolm D, Matheson, David, Millman, Robin, Russell, J Martin, Thalmann, George N, Amos, Claire L, Alonzi, Roberto, Bahl, Amit, Birtle, Alison, Din, Omar, Douis, Hassan, Eswar, Chinnamani, Gale, Joanna, Gannon, Melissa R, Jonnada, Sai, Khaksar, Sara, Lester, Jason F, O'Sullivan, Joe M, Parikh, Omi A, Pedley, Ian D, Pudney, Delia M, Sheehan, Denise J, Srihari, Narayanan Nair, Tran, Anna T H, Parmar, Mahesh K B, Sydes, Matthew R

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National implementation of multi‐parametric magnetic resonance imaging for prostate cancer detection – recommendations from a UK consensus meeting von Brizmohun Appayya, Mrishta, Adshead, Jim, Ahmed, Hashim U., Allen, Clare, Bainbridge, Alan, Barrett, Tristan, Giganti, Francesco, Graham, John, Haslam, Phil, Johnston, Edward W., Kastner, Christof, Kirkham, Alexander P.S., Lipton, Alexandra, McNeill, Alan, Moniz, Larissa, Moore, Caroline M., Nabi, Ghulam, Padhani, Anwar R., Parker, Chris, Patel, Amit, Pursey, Jacqueline, Richenberg, Jonathan, Staffurth, John, der Meulen, Jan, Walls, Darren, Punwani, Shonit

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Coronary CT Angiography and 5-Year Risk of Myocardial Infarction von Newby, David E, Adamson, Philip D, Berry, Colin, Boon, Nicholas A, Dweck, Marc R, Flather, Marcus, Forbes, John, Hunter, Amanda, Lewis, Stephanie, MacLean, Scott, Mills, Nicholas L, Norrie, John, Roditi, Giles, Shah, Anoop S V, Timmis, Adam D, van Beek, Edwin J R, Williams, Michelle C

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CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice von Mancuso, Renzo, Fryatt, Gemma, Cleal, Madeleine, Obst, Juliane, Pipi, Elena, Monzón-Sandoval, Jimena, Ribe, Elena, Winchester, Laura, Webber, Caleb, Nevado, Alejo, Jacobs, Tom, Austin, Nigel, Theunis, Clara, Grauwen, Karolien, Daniela Ruiz, Eva, Mudher, Amrit, Vicente-Rodriguez, Marta, Parker, Christine A, Simmons, Camilla, Cash, Diana, Richardson, Jill, Jones, Declan N C, Lovestone, Simon, Gómez-Nicola, Diego, Perry, V Hugh

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Inflammatory biomarkers in Alzheimer's disease plasma von Morgan, Angharad R., Touchard, Samuel, Barkhof, Frederik, Bertram, Lars, Bos, Isabelle, Dobricic, Valerija, Frisoni, Giovanni, Frölich, Lutz, Gabel, Silvey, Kettunen, Petronella, Lleó, Alberto, Martinez-Lage, Pablo, Mecocci, Patrizia, Meersmans, Karen, Molinuevo, José Luis, Peyratout, Gwendoline, Popp, Julius, Richardson, Jill, Scheltens, Philip, Soininen, Hikka, Tsolaki, Magda, Vos, Stephanie, Wahlund, Lars-Olof, Wallin, Anders, Westwood, Sarah, Lovestone, Simon, Bullmore, Edward T., Bhatti, Junaid, Chamberlain, Samuel J., Crofts, Anna L., Foster, Andrew C., Kitzbichler, Manfred G., Lynall, Mary-Ellen, Maurice, Christina, St George Hyslop, Peter, Turner, Lorinda, Vertes, Petra, Widmer, Barry, Williams, Guy B., Morgan, B. Paul, Leckey, Claire A., Morgan, Angharad R., O'Hagan, Caroline, Cavanagh, Jonathan, Deith, Catherine, McColl, Alison, Scouller, Paul, Sutherland, Murray, Khan, Shahid, Murphy, Phil, Patel, Jai, de Boer, Peter, Drevets, Wayne C., Isaac, John, Bhattacharya, Anindya, Carruthers, Nick, Kolb, Hartmuth, Pariante, Carmine M., Cash, Diana, Mondelli, Valeria, Nikkheslat, Naghmeh, Sheridan, Hannah, Simmons, Camilla, Singh, Nisha, Van Loo, Victoria, Vicente-Rodriguez, Marta, Worrell, Courtney, Plath, Niels, Egebjerg, Jan, Gastambide, Francois, Pederson, Jan Torleif, Campbell, Brian, Möller, Thomas, Nelson, Bob, Zorn, Stevin, O'Connor, Jason, Attenburrow, Mary Jane, Baird, Alison, Benjamin, Jithen, Clare, Stuart, Cowen, Philip, Huang, I-Shu (Dante), Jones, Helen, Lovestone, Simon, Mada, Francisca, Oladejo, Akintayo, Ribe, Elena, Smith, Katy, Vyas, Anviti, Sporn, Jonathan, Fryatt, Gemma, Gomez-Nicola, Diego, Mancuso, Renzo, Reynolds, Richard, Cercignani, Mara, Clarke, Charlotte L., Hoskins, Elizabeth, Murray, Rosemary, Wlazly, Dominika, Mount, Howard

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Interferon-ε is a tumour suppressor and restricts ovarian cancer von Marks, Zoe R. C., Campbell, Nicole K., Mangan, Niamh E., Vandenberg, Cassandra J., Gearing, Linden J., Matthews, Antony Y., Gould, Jodee A., Tate, Michelle D., Wray-McCann, Georgie, Ying, Le, Rosli, Sarah, Brockwell, Natasha, Parker, Belinda S., Lim, San S., Bilandzic, Maree, Christie, Elizabeth L., Stephens, Andrew N., de Geus, Eveline, Wakefield, Matthew J., Ho, Gwo-Yaw, McNally, Orla, McNeish, Iain A., Bowtell, David D. L., de Weerd, Nicole A., Scott, Clare L., Bourke, Nollaig M., Hertzog, Paul J.

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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7 von Curran, Martin D., Roy, Sunando, Shaaban, Sharif, de Cesare, Mariateresa, Stark, Richard, Palmer, Steve, Jeffries, Aaron R., da Silva Filipe, Ana, Davis, Thomas, Collins, Jennifer, Williams, Thomas, Haldenby, Sam T., Cook, Kate, Davies, Robert, Kay, Sally, Poplawski, Radoslaw, Reynolds, Nicola, Moll, Robin J., Thornton, Alicia, Gatica-Wilcox, Bree, Louka, Stavroula F., Kraemer, Moritz U.G., Freeman, Timothy M., Abudahab, Khalil, Menegazzo, Mirko, Mason, Jenifer, Holmes, Alison, Curran, Tanya, Mookerjee, Siddharth, Munn, Robert, Davies, Alisha, Smith, Nikki, Cormie, Claire, Lo, Stephanie, Auckland, Cressida, Mollett, Guy, Harper, Katherine L., Bonner, Stephen, Padgett, Debra, Burton-Fanning, Shirelle, Bedford, Luke, Coupland, Lindsay, Wright, Victoria, Ball, Jonathan, Boswell, Tim, Duckworth, Nichola, Williams, Rebecca, Cogger, Benjamin J., Farr, Ben W., Thurston, Scott A.J., Bronner, Iraad F., Aigrain, Louise, Gallagher, Michael D., Miah, Shahjahan, Ramsay, Mary, Schaefer, Ulf, Manesis, Nikos, Allara, Elias, Nichols, Jenna, Vamos, Edith E., Hughes, Margaret, Wilson, Harry D., Wilson, Rebekah E., Thompson, Thomas, O’Brien, Sarah, Rudder, Steven, McCluggage, Kathryn, Bonfield, James, Liddle, Jennifier, Rowe, Will, Bevan, Paul, Clark, Richard, Cutts, Tim, Densem, Aiden, Dodd, David, Griffiths, Coline, Kay, Keely, Lensing, Stefanie, Lewis-Wade, Amanah, Mamun, Irfan, Martin, Matt, McClintock, Jo, Nathwani, Claire, Nicholson, Jon, Patel, Gaurang, Petersen, Arabella, Reynolds, Joe, Rudd, Luke, Sadri, Ramin, Sizer, Dale, Soria, Carmen Diaz, Sousa, Catarina, Squares, Janet, Stickland, Tim, Still, Ian, Symons, Edward, Uphill, James, Van, Philip Jansen, Voak, Paul, Corti, Davide

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Computerized Analysis of Retinal Vessel Width and Tortuosity in Premature Infants von Wilson, Clare M, Cocker, Kenneth D, Moseley, Merrick J, Paterson, Carl, Clay, Simon T, Schulenburg, William E, Mills, Monte D, Ells, Anna L, Parker, Kim H, Quinn, Graham E, Fielder, Alistair R, Ng, Jeffrey

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Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43 von Moujalled, Diane, James, Janine L, Yang, Shu, Zhang, Katharine, Duncan, Clare, Moujalled, Donia M, Parker, Sarah J, Caragounis, Aphrodite, Lidgerwood, Grace, Turner, Bradley J, Atkin, Julie D, Grubman, Alexandra, Liddell, Jeffrey R, Proepper, Christian, Boeckers, Tobias M, Kanninen, Katja M, Blair, Ian, Crouch, Peter J, White, Anthony R

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Sex differences in lower urinary tract biology and physiology von Abelson, Benjamin, Sun, Daniel, Que, Lauren, Nebel, Rebecca A, Baker, Dylan, Popiel, Patrick, Amundsen, Cindy L, Chai, Toby, Close, Clare, DiSanto, Michael, Fraser, Matthew O, Kielb, Stephanie J, Kuchel, George, Mueller, Elizabeth R, Palmer, Mary H, Parker-Autry, Candace, Wolfe, Alan J, Damaser, Margot S

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Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support–Free Days in Patients Hospitalized With COVID-19: A Randomized Clinic... von Lawler, Patrick R, Derde, Lennie P. G, van de Veerdonk, Frank L, McVerry, Bryan J, Huang, David T, Berry, Lindsay R, Lorenzi, Elizabeth, van Kimmenade, Roland, Gommans, Frank, Vaduganathan, Muthiah, Leaf, David E, Baron, Rebecca M, Kim, Edy Y, Frankfurter, Claudia, Epelman¸, Slava, Kwan, Yvonne, Grieve, Richard, O'Neill, Stephen, Sadique, Zia, Puskarich, Michael, Marshall, John C, Higgins, Alisa M, Mouncey, Paul R, Rowan, Kathryn M, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Au, Carly, Beane, Abi, van Bentum-Puijk, Wilma, Bonten, Marc J. M, Bradbury, Charlotte A, Brunkhorst, Frank M, Burrell, Aidan, Buzgau, Adrian, Buxton, Meredith, Cecconi, Maurizio, Cheng, Allen C, Cove, Matthew, Detry, Michelle A, Estcourt, Lise J, Ezekowitz, Justin, Fitzgerald, Mark, Gattas, David, Godoy, Lucas C, Goossens, Herman, Haniffa, Rashan, Harrison, David A, Hills, Thomas, Horvat, Christopher M, Ichihara, Nao, Lamontagne, Francois, Linstrum, Kelsey M, McAuley, Daniel F, McGlothlin, Anna, McGuinness, Shay P, McQuilten, Zoe, Murthy, Srinivas, Nichol, Alistair D, Owen, David R. J, Parke, Rachael L, Parker, Jane C, Pollock, Katrina M, Reyes, Luis Felipe, Saito, Hiroki, Santos, Marlene S, Saunders, Christina T, Seymour, Christopher W, Shankar-Hari, Manu, Singh, Vanessa, Turgeon, Alexis F, Turner, Anne M, Zarychanski, Ryan, Green, Cameron, Lewis, Roger J, Angus, Derek C, Berry, Scott, Gordon, Anthony C, McArthur, Colin J, Webb, Steve A

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Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multista... von Pal, Suvankar, Chataway, Jeremy, Swingler, Robert, Macleod, Malcolm R, Carragher, Neil O, Hardingham, Giles, Selvaraj, Bhuvaneish Thangaraj, Smith, Colin, Wong, Charis, Newton, Judith, Lyle, Dawn, Stenson, Amy, Dakin, Rachel S, Ihenacho, Amarachi, Colville, Shuna, Mehta, Arpan R, Stallard, Nigel, Carpenter, James R, Parker, Richard A, Keerie, Catriona, Weir, Christopher J, Virgo, Bruce, Morris, Stevie, Waters, Nicola, Gray, Beverley, MacDonald, Donald, MacDonald, Euan, Parmar, Mahesh K B, Chandran, Siddharthan, Gorrie, George, Morrison, Ian, Duncan, Callum, Carod Artal, Javier, Williams, Timothy, Srinivasan, Venkataramanan, Radunovic, Aleksandar, Pinto, Ashwin, Hamdalla, Hisham, Roberts, Rhys, Garcia- Reitboeck, Pablo, Harrower, Timothy, Mamutse, Godwin, Crawley, Francesca, Galton, Clare, Dawson, Kenneth, Forbes, Raeburn, Hillier, Charles, McDermott, Christopher, Forbes, Deborah, Bozkurt, Hatice, Stavrou, Maria, Kearns, Patrick, Breen, David, Kurucu King, Hatice, Elliot, Elizabeth, Beswick, Emily, Williamson, Jill, Cucurachi, Paolo, McLennan, Lucy

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