Accurate and comprehensive sequencing of personal genomes von Ajay, Subramanian S, Parker, Stephen C J, Abaan, Hatice Ozel, Fajardo, Karin V Fuentes, Margulies, Elliott H

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Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures von Rai, Vivek, Quang, Daniel X., Erdos, Michael R., Cusanovich, Darren A., Daza, Riza M., Narisu, Narisu, Zou, Luli S., Didion, John P., Guan, Yuanfang, Shendure, Jay, Parker, Stephen C.J., Collins, Francis S.

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Super-enhancers delineate disease-associated regulatory nodes in T cells von Vahedi, Golnaz, Kanno, Yuka, Furumoto, Yasuko, Jiang, Kan, Parker, Stephen C. J., Erdos, Michael R., Davis, Sean R., Roychoudhuri, Rahul, Restifo, Nicholas P., Gadina, Massimo, Tang, Zhonghui, Ruan, Yijun, Collins, Francis S., Sartorelli, Vittorio, O’Shea, John J.

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A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus von Roman, Tamara S, Cannon, Maren E, Vadlamudi, Swarooparani, Buchkovich, Martin L, Wolford, Brooke N, Welch, Ryan P, Morken, Mario A, Kwon, Grace J, Varshney, Arushi, Kursawe, Romy, Wu, Ying, Jackson, Anne U, Erdos, Michael R, Kuusisto, Johanna, Laakso, Markku, Scott, Laura J, Boehnke, Michael, Collins, Francis S, Parker, Stephen C J, Stitzel, Michael L, Mohlke, Karen L

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Untangling the genetics of beta cell dysfunction and death in type 1 diabetes von Robertson, Catherine C., Elgamal, Ruth M., Henry-Kanarek, Belle A., Arvan, Peter, Chen, Shuibing, Dhawan, Sangeeta, Eizirik, Decio L., Kaddis, John S., Vahedi, Golnaz, Parker, Stephen C.J., Gaulton, Kyle J., Soleimanpour, Scott A.

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Combinatorial transcription factor profiles predict mature and functional human islet α and β cells von Shrestha, Shristi, Saunders, Diane C, Walker, John T, Camunas-Soler, Joan, Dai, Xiao-Qing, Haliyur, Rachana, Aramandla, Radhika, Poffenberger, Greg, Prasad, Nripesh, Bottino, Rita, Stein, Roland, Cartailler, Jean-Philippe, Parker, Stephen Cj, MacDonald, Patrick E, Levy, Shawn E, Powers, Alvin C, Brissova, Marcela

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CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression von Yao, Hui, Hannum, Douglas F., Zhai, Yiwen, Hill, Sophie F., Albanus, Ricardo D.’Oliveira, Lou, Wenjia, Skidmore, Jennifer M., Sanchez, Gilson, Saiakhova, Alina, Bielas, Stephanie L., Scacheri, Peter, Ljungman, Mats, Parker, Stephen C. J., Martin, Donna M.

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143 EVALUATING THE CLINICAL UTILITY OF PERIPHERAL BLOOD SAMPLES FOR MOLECULAR EVALUATION OF MDS BY SNP-A von Andersen, E.F, Salama, M.E, Sederberg, M.C, Toydemir, R.M, Kovacsovics, T.J, Parker, C.J, Rodgers, G.M, Shami, P.J, Deininger, M.W, South, S.T

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Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection von Shibata, Yoichiro, Sheffield, Nathan C, Fedrigo, Olivier, Babbitt, Courtney C, Wortham, Matthew, Tewari, Alok K, London, Darin, Song, Lingyun, Lee, Bum-Kyu, Iyer, Vishwanath R, Parker, Stephen C J, Margulies, Elliott H, Wray, Gregory A, Furey, Terrence S, Crawford, Gregory E

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Somatic Mutations in MAP3K5 Attenuate Its Proapoptotic Function in Melanoma through Increased Binding to Thioredoxin von Prickett, Todd D., Zerlanko, Brad, Gartner, Jared J., Parker, Stephen C.J., Dutton-Regester, Ken, Lin, Jimmy C., Teer, Jamie K., Wei, Xiaomu, Jiang, Jiji, NISC Comparative Sequencing Program, Chen, Guo, Davies, Michael A., Gershenwald, Jeffrey E., Robinson, William, Robinson, Steven, Hayward, Nicholas K., Rosenberg, Steven A., Margulies, Elliott H., Samuels, Yardena

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Global dynamics of stage-specific transcription factor binding during thymocyte development von Hosoya, Tomonori, D’Oliveira Albanus, Ricardo, Hensley, John, Myers, Greggory, Kyono, Yasuhiro, Kitzman, Jacob, Parker, Stephen C. J., Engel, James Douglas

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Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect von Sommer, Wolfgang H, Lidström, Jessica, Sun, Hui, Passer, Derek, Eskay, Robert, Parker, Stephen C.J, Witt, Stephanie H, Zimmermann, Ulrich S, Nieratschker, Vanessa, Rietschel, Marcella, Margulies, Elliott H, Palkovits, Miklós, Laucht, Manfred, Heilig, Markus

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Voltage security enhancement via coordinated control von Qiang Wu, Popovic, D.H., Hill, D.J., Parker, C.J.

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Machine Learning to Predict Anti–Tumor Necrosis Factor Drug Responses of Rheumatoid Arthritis Patients by Integrating Clinical and Genetic Markers von Guan, Yuanfang, Zhang, Hongjiu, Quang, Daniel, Wang, Ziyan, Parker, Stephen C. J., Pappas, Dimitrios A., Kremer, Joel M., Zhu, Fan

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GBshape: a genome browser database for DNA shape annotations von Chiu, Tsu-Pei, Yang, Lin, Zhou, Tianyin, Main, Bradley J., Parker, Stephen C.J., Nuzhdin, Sergey V., Tullius, Thomas D., Rohs, Remo

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Usability of Geographic Information: Current challenges and future directions von Brown, M., Sharples, S., Harding, J., Parker, C.J., Bearman, N., Maguire, M., Forrest, D., Haklay, M., Jackson, M.

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Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits von Orchard, Peter, Manickam, Nandini, Ventresca, Christa, Vadlamudi, Swarooparani, Varshney, Arushi, Rai, Vivek, Kaplan, Jeremy, Lalancette, Claudia, Mohlke, Karen L, Gallagher, Katherine, Burant, Charles F, Parker, Stephen C J

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Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants von Parker, Stephen C. J., Stitzel, Michael L., Taylor, D. Leland, Orozco, Jose Miguel, Erdos, Michael R., Akiyama, Jennifer A., van Bueren, Kelly Lammerts, Chines, Peter S., Narisu, Narisu, Black, Brian L., Visel, Axel, Pennacchio, Len A., Collins, Francis S.

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Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle von Taylor, D. Leland, Jackson, Anne U., Narisu, Narisu, Hemani, Gibran, Erdos, Michael R., Chines, Peter S., Swift, Amy, Idol, Jackie, Didion, John P., Welch, Ryan P., Kinnunen, Leena, Saramies, Jouko, Lakka, Timo A., Laakso, Markku, Tuomilehto, Jaakko, Parker, Stephen C. J., Koistinen, Heikki A., Smith, George Davey, Boehnke, Michael, Scott, Laura J., Birney, Ewan, Collins, Francis S.

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The methodological and ethical concerns of genetic studies of same-sex sexual behavior von Ventresca, Christa, Martschenko, Daphne O., Wedow, Robbee, Civelek, Mete, Tabery, James, Carlson, Jedidiah, Parker, Stephen C.J., Ramos, Paula S.

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