Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program von Khacho, Mireille, Clark, Alysen, Svoboda, Devon S., Azzi, Joelle, MacLaurin, Jason G., Meghaizel, Cynthia, Sesaki, Hiromi, Lagace, Diane C., Germain, Marc, Harper, Mary-Ellen, Park, David S., Slack, Ruth S.

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Pathological Axonal Death through a MAPK Cascade that Triggers a Local Energy Deficit von Yang, Jing, Wu, Zhuhao, Renier, Nicolas, Simon, David J., Uryu, Kunihiro, Park, David S., Greer, Peter A., Tournier, Cathy, Davis, Roger J., Tessier-Lavigne, Marc

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OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand von Patten, David A, Wong, Jacob, Khacho, Mireille, Soubannier, Vincent, Mailloux, Ryan J, Pilon-Larose, Karine, MacLaurin, Jason G, Park, David S, McBride, Heidi M, Trinkle-Mulcahy, Laura, Harper, Mary-Ellen, Germain, Marc, Slack, Ruth S

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Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment von Greene, Andrew W, Grenier, Karl, Aguileta, Miguel A, Muise, Stephanie, Farazifard, Rasoul, Haque, M Emdadul, McBride, Heidi M, Park, David S, Fon, Edward A

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Myocardial infarction accelerates breast cancer via innate immune reprogramming von Koelwyn, Graeme J., Newman, Alexandra A. C., Afonso, Milessa S., van Solingen, Coen, Corr, Emma M., Brown, Emily J., Albers, Kathleen B., Yamaguchi, Naoko, Narke, Deven, Schlegel, Martin, Sharma, Monika, Shanley, Lianne C., Barrett, Tessa J., Rahman, Karishma, Mezzano, Valeria, Fisher, Edward A., Park, David S., Newman, Jonathan D., Quail, Daniela F., Nelson, Erik R., Caan, Bette J., Jones, Lee W., Moore, Kathryn J.

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Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA von Galehdar, Zohreh, Swan, Patrick, Fuerth, Benjamin, Callaghan, Steven M, Park, David S, Cregan, Sean P

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PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress von Huang, En, Qu, Dianbo, Huang, Tianwen, Rizzi, Nicoletta, Boonying, Wassamon, Krolak, Dorothy, Ciana, Paolo, Woulfe, John, Klein, Christine, Slack, Ruth S., Figeys, Daniel, Park, David S.

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Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s disease von Kim, Kwang Soo, Marcogliese, Paul C., Yang, Jungwoo, Callaghan, Steve M., Resende, Virginia, Abdel-Messih, Elizabeth, Marras, Connie, Visanji, Naomi P., Huang, Jana, Schlossmacher, Michael G., Trinkle-Mulcahy, Laura, Slack, Ruth S., Lang, Anthony E., Park, David S.

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Cardiac Pressure Overload Decreases ETV1 Expression in the Left Atrium, Contributing to Atrial Electrical and Structural Remodeling von Yamaguchi, Naoko, Xiao, Junhua, Narke, Deven, Shaheen, Devin, Lin, Xianming, Offerman, Erik, Khodadadi-Jamayran, Alireza, Shekhar, Akshay, Choy, Alex, Wass, Sojin Y., Van Wagoner, David R., Chung, Mina K., Park, David S.

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DJ-1/PARK7 Is an Important Mediator of Hypoxia-Induced Cellular Responses von Vasseur, Sophie, Afzal, Samia, Tardivel-Lacombe, Joël, Park, David S., Iovanna, Juan Lucio, Wah Mak, Tak

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Comparative analysis of Parkinson's disease–associated genes in mice reveals altered survival and bioenergetics of Parkin-deficient dopamine neurons von Giguère, Nicolas, Pacelli, Consiglia, Saumure, Caroline, Bourque, Marie-Josée, Matheoud, Diana, Levesque, Daniel, Slack, Ruth S., Park, David S., Trudeau, Louis-Éric

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Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias von Park, David S, Cerrone, Marina, Morley, Gregory, Vasquez, Carolina, Fowler, Steven, Liu, Nian, Bernstein, Scott A, Liu, Fang-Yu, Zhang, Jie, Rogers, Christopher S, Priori, Silvia G, Chinitz, Larry A, Fishman, Glenn I

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Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures von Hakimi, Mansoureh, Selvanantham, Thirumahal, Swinton, Erika, Padmore, Ruth F., Tong, Youren, Kabbach, Ghassan, Venderova, Katerina, Girardin, Stephen E., Bulman, Dennis E., Scherzer, Clemens R., LaVoie, Matthew J., Gris, Denis, Park, David S., Angel, Jonathan B., Shen, Jie, Philpott, Dana J., Schlossmacher, Michael G.

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Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP von Haque, M. Emdadul, Thomas, Kelly J, D'Souza, Cheryl, Callaghan, Steve, Kitada, Tohru, Slack, Ruth S, Fraser, Paul, Cookson, Mark R, Tandon, Anurag, Park, David S

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Opposing Regulation of Sox2 by Cell-Cycle Effectors E2f3a and E2f3b in Neural Stem Cells von Julian, Lisa M., Vandenbosch, Renaud, Pakenham, Catherine A., Andrusiak, Matthew G., Nguyen, Angela P., McClellan, Kelly A., Svoboda, Devon S., Lagace, Diane C., Park, David S., Leone, Gustavo, Blais, Alexandre, Slack, Ruth S.

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PFTK1 kinase regulates axogenesis during development via RhoA activation von González, Yasmilde Rodríguez, Kamkar, Fatemeh, Jafar-nejad, Paymaan, Wang, Suzi, Qu, Dianbo, Alvarez, Leticia Sanchez, Hawari, Dina, Sonnenfeld, Margaret, Slack, Ruth S, Albert, Paul R, Park, David S, Joselin, Alvin

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Hypersensitivity of DJ-1-Deficient Mice to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyrindine (MPTP) and Oxidative Stress von Kim, Raymond H., Smith, Patrice D., Aleyasin, Hossein, Hayley, Shawn, Mount, Matthew P., Pownall, Scott, Wakeham, Andrew, You-Ten, Annick J., Kalia, Suneil K., Horne, Patrick, Westaway, David, Lozano, Andres M., Anisman, Hymie, Park, David S., Mak, Tak W.

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BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival von Qu, Dianbo, Hage, Ali, Don-Carolis, Katie, Huang, En, Joselin, Alvin, Safarpour, Farzaneh, Marcogliese, Paul C., Rousseaux, Maxime W.C., Hewitt, Sarah J., Huang, Tianwen, Im, Doo-Soon, Callaghan, Steve, Dewar-Darch, Danielle, Figeys, Daniel, Slack, Ruth S., Park, David S.

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Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure von Park, David S., Shekhar, Akshay, Marra, Christopher, Lin, Xianming, Vasquez, Carolina, Solinas, Sergio, Kelley, Kevin, Morley, Gregory, Goldfarb, Mitchell, Fishman, Glenn I.

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The Mitochondrial Inner Membrane GTPase, Optic Atrophy 1 (Opa1), Restores Mitochondrial Morphology and Promotes Neuronal Survival following Excitotoxicity von Jahani-Asl, Arezu, Pilon-Larose, Karine, Xu, William, MacLaurin, Jason G., Park, David S., McBride, Heidi M., Slack, Ruth S.

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