A calcineurin- and NFAT-dependent pathway is involved in  -synuclein-induced degeneration of midbrain dopaminergic neurons von Luo, J., Sun, L., Lin, X., Liu, G., Yu, J., Parisiadou, L., Xie, C., Ding, J., Cai, H.

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3.141 NURR1 DETERMINES THE PREFERENTIAL DEGENERATION OF MIDBRAIN DOPAMINERGIC NEURONS IN A PARKINSON'S DISEASE MOUSE MODEL von Lin, X, Parisiadou, L, Liu, G, Yu, J, Cai, H

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Conditional Expression of Parkinson's Disease-Related Mutant  -Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription... von Lin, X., Parisiadou, L., Sgobio, C., Liu, G., Yu, J., Sun, L., Shim, H., Gu, X.-L., Luo, J., Long, C.-X., Ding, J., Mateo, Y., Sullivan, P. H., Wu, L.-G., Goldstein, D. S., Lovinger, D., Cai, H.

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Regulation of MnSOD enzymatic activity by Sirt3 connects the mitochondrial acetylome signaling networks to aging and carcinogenesis von Tao, Randa, Vassilopoulos, Athanassios, Parisiadou, Loukia, Yan, Yufan, Gius, David

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Closing the structure-to-function gap for LRRK2 von Tokars, Valerie, Chen, Chuyu, Parisiadou, Loukia

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Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations von Chen, Chuyu, Soto, Giulia, Dumrongprechachan, Vasin, Bannon, Nicholas, Kang, Shuo, Kozorovitskiy, Yevgenia, Parisiadou, Loukia

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MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein von Cho, Hyun Jin, Liu, Guoxiang, Jin, Seok Min, Parisiadou, Loukia, Xie, Chengsong, Yu, Jia, Sun, Lixin, Ma, Bo, Ding, Jinhui, Vancraenenbroeck, Renée, Lobbestael, Evy, Baekelandt, Veerle, Taymans, Jean-Marc, He, Ping, Troncoso, Juan C, Shen, Yong, Cai, Huaibin

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Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis von Parisiadou, Loukia, Xie, Chengsong, Cho, Hyun Jin, Lin, Xian, Gu, Xing-Long, Long, Cai-Xia, Lobbestael, Evy, Baekelandt, Veerle, Taymans, Jean-Marc, Sun, Lixin, Cai, Huaibin

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Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy von Liu, Guoxiang, Park, Seong-Hoon, Imbesi, Marta, Nathan, William Joseph, Zou, Xianghui, Zhu, Yueming, Jiang, Haiyan, Parisiadou, Loukia, Gius, David

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The Chaperone Activity of Heat Shock Protein 90 Is Critical for Maintaining the Stability of Leucine-Rich Repeat Kinase 2 von Wang, Lizhen, Xie, Chengsong, Greggio, Elisa, Parisiadou, Loukia, Shim, Hoon, Sun, Lixin, Chandran, Jayanth, Lin, Xian, Lai, Chen, Yang, Wan-Jou, Moore, Darren J, Dawson, Ted M, Dawson, Valina L, Chiosis, Gabriela, Cookson, Mark R, Cai, Huaibin

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LRRK2 at Striatal Synapses: Cell-Type Specificity and Mechanistic Insights von Skelton, Patrick D, Tokars, Valerie, Parisiadou, Loukia

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LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity von Parisiadou, Loukia, Yu, Jia, Sgobio, Carmelo, Xie, Chengsong, Liu, Guoxiang, Sun, Lixin, Gu, Xing-Long, Lin, Xian, Crowley, Nicole A, Lovinger, David M, Cai, Huaibin

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Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11α von Parisiadou, Loukia, Efthimiopoulos, Spiros

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Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein von Lin, Xian, Parisiadou, Loukia, Gu, Xing-Long, Wang, Lizhen, Shim, Hoon, Sun, Lixin, Xie, Chengsong, Long, Cai-Xia, Yang, Wan-Jou, Ding, Jinhui, Chen, Zsu Zsu, Gallant, Paul E., Tao-Cheng, Jung-Hwa, Rudow, Gay, Troncoso, Juan C., Liu, Zhihua, Li, Zheng, Cai, Huaibin

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Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export von Cho, Hyun Jin, Yu, Jia, Xie, Chengsong, Rudrabhatla, Parvathi, Chen, Xi, Wu, Junbing, Parisiadou, Loukia, Liu, Guoxiang, Sun, Lixin, Ma, Bo, Ding, Jinhui, Liu, Zhihua, Cai, Huaibin

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Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription... von Lin, Xian, Parisiadou, Loukia, Sgobio, Carmelo, Liu, Guoxiang, Yu, Jia, Sun, Lixin, Shim, Hoon, Gu, Xing-Long, Luo, Jing, Long, Cai-Xia, Ding, Jinhui, Mateo, Yolanda, Sullivan, Patricia H, Wu, Ling-Gang, Goldstein, David S, Lovinger, David, Cai, Huaibin

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R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations von Xenias, Harry S., Chen, Chuyu, Kang, Shuo, Cherian, Suraj, Situ, Xiaolei, Shanmugasundaram, Bharanidharan, Liu, Guoxiang, Scesa, Giuseppe, Chan, C. Savio, Parisiadou, Loukia

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Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic... von Liu, Guoxiang, Sgobio, Carmelo, Gu, Xinglong, Sun, Lixin, Lin, Xian, Yu, Jia, Parisiadou, Loukia, Xie, Chengsong, Sastry, Namratha, Ding, Jinhui, Lohr, Kelly M, Miller, Gary W, Mateo, Yolanda, Lovinger, David M, Cai, Huaibin

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Homer2 and Homer3 interact with amyloid precursor protein and inhibit Aβ production von Parisiadou, Loukia, Bethani, Ioanna, Michaki, Vasiliki, Krousti, Kaliopi, Rapti, Georgia, Efthimiopoulos, Spiros

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LRRK2 function on actin and microtubule dynamics in Parkinson's disease von Parisiadou, Loukia, Cai, Huaibin

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