Disease Models & Mechanisms announces a new Editor-in-Chief von Vyas, Paresh

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The Graft-Versus-Leukemia Effect in AML von Sweeney, Connor, Vyas, Paresh

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Assessment of Minimal Residual Disease in Standard-Risk AML von Ivey, Adam, Hills, Robert K, Simpson, Michael A, Jovanovic, Jelena V, Gilkes, Amanda, Grech, Angela, Patel, Yashma, Bhudia, Neesa, Farah, Hassan, Mason, Joanne, Wall, Kerry, Akiki, Susanna, Griffiths, Michael, Solomon, Ellen, McCaughan, Frank, Linch, David C, Gale, Rosemary E, Vyas, Paresh, Freeman, Sylvie D, Russell, Nigel, Burnett, Alan K, Grimwade, David

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Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party von Schuurhuis, Gerrit J., Heuser, Michael, Freeman, Sylvie, Béné, Marie-Christine, Buccisano, Francesco, Cloos, Jacqueline, Grimwade, David, Haferlach, Torsten, Hills, Robert K., Hourigan, Christopher S., Jorgensen, Jeffrey L., Kern, Wolfgang, Lacombe, Francis, Maurillo, Luca, Preudhomme, Claude, van der Reijden, Bert A., Thiede, Christian, Venditti, Adriano, Vyas, Paresh, Wood, Brent L., Walter, Roland B., Döhner, Konstanze, Roboz, Gail J., Ossenkoppele, Gert J.

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Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response von Amatangelo, Michael D., Quek, Lynn, Shih, Alan, Stein, Eytan M., Roshal, Mikhail, David, Muriel D., Marteyn, Benoit, Farnoud, Noushin Rahnamay, de Botton, Stephane, Bernard, Olivier A., Wu, Bin, Yen, Katharine E., Tallman, Martin S., Papaemmanuil, Elli, Penard-Lacronique, Virginie, Thakurta, Anjan, Vyas, Paresh, Levine, Ross L.

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Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia von Stein, Eytan M., DiNardo, Courtney D., Pollyea, Daniel A., Fathi, Amir T., Roboz, Gail J., Altman, Jessica K., Stone, Richard M., DeAngelo, Daniel J., Levine, Ross L., Flinn, Ian W., Kantarjian, Hagop M., Collins, Robert, Patel, Manish R., Frankel, Arthur E., Stein, Anthony, Sekeres, Mikkael A., Swords, Ronan T., Medeiros, Bruno C., Willekens, Christophe, Vyas, Paresh, Tosolini, Alessandra, Xu, Qiang, Knight, Robert D., Yen, Katharine E., Agresta, Sam, de Botton, Stephane, Tallman, Martin S.

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New directions for emerging therapies in acute myeloid leukemia: the next chapter von Daver, Naval, Wei, Andrew H., Pollyea, Daniel A., Fathi, Amir T., Vyas, Paresh, DiNardo, Courtney D.

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Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells von Karamitros, Dimitris, Stoilova, Bilyana, Aboukhalil, Zahra, Hamey, Fiona, Reinisch, Andreas, Samitsch, Marina, Quek, Lynn, Otto, Georg, Repapi, Emmanouela, Doondeea, Jessica, Usukhbayar, Batchimeg, Calvo, Julien, Taylor, Stephen, Goardon, Nicolas, Six, Emmanuelle, Pflumio, Francoise, Porcher, Catherine, Majeti, Ravindra, Göttgens, Berthold, Vyas, Paresh

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Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia von Giustacchini, Alice, Thongjuea, Supat, Barkas, Nikolaos, Woll, Petter S, Povinelli, Benjamin J, Booth, Christopher A G, Sopp, Paul, Norfo, Ruggiero, Rodriguez-Meira, Alba, Ashley, Neil, Jamieson, Lauren, Vyas, Paresh, Anderson, Kristina, Segerstolpe, Åsa, Qian, Hong, Olsson-Strömberg, Ulla, Mustjoki, Satu, Sandberg, Rickard, Jacobsen, Sten Eirik W, Mead, Adam J

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Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment von Mussai, Francis, De Santo, Carmela, Abu-Dayyeh, Issa, Booth, Sarah, Quek, Lynn, McEwen-Smith, Rosanna M., Qureshi, Amrana, Dazzi, Francesco, Vyas, Paresh, Cerundolo, Vincenzo

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The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis von Muskens, Ivo S., Li, Shaobo, Jackson, Thomas, Elliot, Natalina, Hansen, Helen M., Myint, Swe Swe, Pandey, Priyatama, Schraw, Jeremy M., Roy, Ritu, Anguiano, Joaquin, Goudevenou, Katerina, Siegmund, Kimberly D., Lupo, Philip J., de Bruijn, Marella F. T. R., Walsh, Kyle M., Vyas, Paresh, Ma, Xiaomei, Roy, Anindita, Roberts, Irene, Wiemels, Joseph L., de Smith, Adam J.

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Results of the Phase I Trial of RG7112, a Small-Molecule MDM2 Antagonist in Leukemia von Andreeff, Michael, Kelly, Kevin R, Yee, Karen, Assouline, Sarit, Strair, Roger, Popplewell, Leslie, Bowen, David, Martinelli, Giovanni, Drummond, Mark W, Vyas, Paresh, Kirschbaum, Mark, Iyer, Swaminathan Padmanabhan, Ruvolo, Vivian, González, Graciela M Nogueras, Huang, Xuelin, Chen, Gong, Graves, Bradford, Blotner, Steven, Bridge, Peter, Jukofsky, Lori, Middleton, Steve, Reckner, Monica, Rueger, Ruediger, Zhi, Jianguo, Nichols, Gwen, Kojima, Kensuke

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DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation von Godfrey, Laura, Crump, Nicholas T., Thorne, Ross, Lau, I-Jun, Repapi, Emmanouela, Dimou, Dimitra, Smith, Alastair L., Harman, Joe R., Telenius, Jelena M., Oudelaar, A. Marieke, Downes, Damien J., Vyas, Paresh, Hughes, Jim R., Milne, Thomas A.

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SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications von Singh, Shalini, Ahmed, Doaa, Dolatshad, Hamid, Tatwavedi, Dharamveer, Schulze, Ulrike, Sanchi, Andrea, Ryley, Sarah, Dhir, Ashish, Carpenter, Lee, Watt, Suzanne M., Roberts, David J., Abdel-Aal, Amal M., Sayed, Sohair K., Mohamed, Somaia A., Schuh, Anna, Vyas, Paresh, Killick, Sally, Kotini, Andriana G., Papapetrou, Eirini P., Wiseman, Daniel H., Pellagatti, Andrea, Boultwood, Jacqueline

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Changing treatment changing prognosis of mutations von Vyas, Paresh

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Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature von Craddock, Charles F, Houlton, Aimee E, Quek, Lynn Swun, Ferguson, Paul, Gbandi, Emma, Roberts, Corran, Metzner, Marlen, Garcia-Martin, Natalia, Kennedy, Alison, Hamblin, Angela, Raghavan, Manoj, Nagra, Sandeep, Dudley, Louise, Wheatley, Keith, McMullin, Mary Frances, Pillai, Srinivas P, Kelly, Richard J, Siddique, Shamyla, Dennis, Michael, Cavenagh, Jamie D, Vyas, Paresh

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Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia von Goardon, Nicolas, Marchi, Emanuele, Atzberger, Ann, Quek, Lynn, Schuh, Anna, Soneji, Shamit, Woll, Petter, Mead, Adam, Alford, Kate A., Rout, Raj, Chaudhury, Salma, Gilkes, Amanda, Knapper, Steve, Beldjord, Kheira, Begum, Suriya, Rose, Susan, Geddes, Nicola, Griffiths, Mike, Standen, Graham, Sternberg, Alexander, Cavenagh, Jamie, Hunter, Hannah, Bowen, David, Killick, Sally, Robinson, Lisa, Price, Andrew, Macintyre, Elizabeth, Virgo, Paul, Burnett, Alan, Craddock, Charles, Enver, Tariq, Jacobsen, Sten Eirik W., Porcher, Catherine, Vyas, Paresh

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EGA for a Convective Regime Over a Vertical Cylinder Stretching Linearly von Vyas, Paresh, Yadav, Kusum

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H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells von Godfrey, Laura, Crump, Nicholas T., O’Byrne, Sorcha, Lau, I-Jun, Rice, Siobhan, Harman, Joe R., Jackson, Thomas, Elliott, Natalina, Buck, Gemma, Connor, Christopher, Thorne, Ross, Knapp, David J. H. F., Heidenreich, Olaf, Vyas, Paresh, Menendez, Pablo, Inglott, Sarah, Ancliff, Philip, Geng, Huimin, Roberts, Irene, Roy, Anindita, Milne, Thomas A.

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Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs von O'Byrne, Sorcha, Elliott, Natalina, Rice, Siobhan, Buck, Gemma, Fordham, Nicholas, Garnett, Catherine, Godfrey, Laura, Crump, Nicholas T., Wright, Gary, Inglott, Sarah, Hua, Peng, Psaila, Bethan, Povinelli, Benjamin, Knapp, David J.H.F., Agraz-Doblas, Antonio, Bueno, Clara, Varela, Ignacio, Bennett, Phillip, Koohy, Hashem, Watt, Suzanne M., Karadimitris, Anastasios, Mead, Adam J., Ancliff, Phillip, Vyas, Paresh, Menendez, Pablo, Milne, Thomas A., Roberts, Irene, Roy, Anindita

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