Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs von Parcon, Paul A., Balasubramaniam, Meenakshisundaram, Ayyadevara, Srinivas, Jones, Richard A., Liu, Ling, Shmookler Reis, Robert J., Barger, Steven W., Mrak, Robert E., Griffin, W. Sue T.

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Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site von Balasubramaniam, Meenakshisundaram, Parcon, Paul A, Bose, Chhanda, Liu, Ling, Jones, Richard A, Farlow, Martin R, Mrak, Robert E, Barger, Steven W, Griffin, W Sue T

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Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls von Ayyadevara, Srinivas, Balasubramaniam, Meenakshisundaram, Parcon, Paul A., Barger, Steven W., Griffin, W. Sue T., Alla, Ramani, Tackett, Alan J., Mackintosh, Samuel G., Petricoin, Emanuel, Zhou, Weidong, Shmookler Reis, Robert J.

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Aging, Alzheimer's, and APOE genotype influence the expression and neuronal distribution patterns of microtubule motor protein dynactin-P50 von Aboud, Orwa, Parcon, Paul A, DeWall, K Mark, Liu, Ling, Mrak, Robert E, Griffin, W Sue T

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261. Ketamine Increases [11C](R)-Rolipram Binding to Phosphodiesterase-4 (PDE4) in Rat and Monkey Brain, an Indirect Biomarker of Increased Camp Signaling von Bardhoshi, Amanda, Parcon, Paul, Liow, Jeih-San, Olsen-Dufour, Amanda, Wu, Shawn, Morse, Cheryl, Pike, Victor, Innis, Robert

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40. Novel Pet Ligand [18F]PF974 can Measure Inflammatory Activation of Phosphodiesterase-4B (PDE4B) in Rat Brain von Knoer, Carson, Parcon, Paul, Wu, Shawn, Cureton, Raven, Lee, Adrian, Liow, Jeih-San, Morse, Cheryl, Pike, Victor, Innis, Robert, Zarate, Carlos

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47. PET Imaging in Healthy Human Brain Can Quantify Cyclooxygenase-1, a Putative Microglial Biomarker of Inflammation von Scrabis, Mia, Ghazanfari, Nafiseh, Parcon, Paul, Liow, Jeih-San, Cureton, Raven, Knoer, Carson, Jenkins, Madeline, Mannes, Andrew, Hong, Jinsoo, Ahmadi, Fatemeh, Santamaria, Jose Montero, Shetty, Umesha, Galassi, Anthony, Wighton, Paul, Greve, Douglas, Zoghbi, Sami, Pike, Victor, Innis, Robert, Zanotti-Fregonara, Paolo

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19. Radioligand Binding to Phosphodiesterase-4B, a Regulator of cAMP, Increases After Acute Alcohol Exposure and Decreases After Chronic Alcohol Exposure in Rats von Olsen-Dufour, Amanda, Tang, Shiyu, Kim, Sung Won, Pearson, Torben, Freaney, Michael, Burkard, Nate, Jenkins, Madeline, Lee, Adrian, Liow, Jeih-San, Parcon, Paul, Wu, Shawn, Vendruscolo, Leandro, Vendruscolo, Janaina, Morse, Cheryl, Ahmadi, Pooyeh, Zoghbi, Sami, Pike, Victor, Fregonara, Paolo Zanotti, Koob, George, Volkow, Nora, Innis, Robert

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PET imaging in rat brain shows opposite effects of acute and chronic alcohol exposure on phosphodiesterase-4B, an indirect biomarker of cAMP activity von Tang, Shiyu, Kim, Sung Won, Olsen-Dufour, Amanda, Pearson, Torben, Freaney, Michael, Singley, Erick, Jenkins, Madeline, Burkard, Nathaniel J, Wozniak, Aaron, Parcon, Paul, Wu, Shawn, Morse, Cheryl L, Jana, Susovan, Liow, Jeih-San, Zoghbi, Sami S, Vendruscolo, Janaina C M, Vendruscolo, Leandro F, Pike, Victor W, Koob, George F, Volkow, Nora D, Innis, Robert B

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Interleukin-1[beta] drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site von Balasubramaniam, Meenakshisundaram, Parcon, Paul A, Bose, Chhanda, Liu, Ling, Jones, Richard A, Farlow, Ma, Mrak, Robert E, Barger, Steven W, Griffin, W. Sue T

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IL-1β INFLUENCES AUTOPHAGY BY MEDIATING UPREGULATION OF PARKIN AND PARKIN NEDDYLATION IN CELL CULTURE AND ANIMAL MODELS, AND MIMICS THE PATTERN SEEN IN AD BRAIN von Griffin, Sue T., Parcon, Paul Andrew, Balasubramaniam, Meenakshisundaram, Bose, Chhanda, Ayyadevara, Srinivas, Jones, Richard A., Farlow, Martin R., Mrak, Robert E.

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P2‐181: IL‐1β INFLUENCES AUTOPHAGY BY MEDIATING UPREGULATION OF PARKIN AND PARKIN NEDDYLATION IN CELL CULTURE AND ANIMAL MODELS, AND MIMICS THE PATTERN SEEN IN AD BRAIN von Griffin, Sue T., Parcon, Paul Andrew, Balasubramaniam, Meenakshisundaram, Bose, Chhanda, Ayyadevara, Srinivas, Jones, Richard A., Farlow, Martin R., Mrak, Robert E.

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Alzheimer’s is associated with neuropathological changes in olfactory bulb that are related to APOE genotype (728.1) von Parcon, Paul, Aboud, Orwa, Biedermann, JoAnn, Mrak, Robert, Griffin, W. Sue

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MOESM2 of Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site von Balasubramaniam, Meenakshisundaram, Parcon, Paul, Bose, Chhanda, Liu, Ling, Jones, Richard, Farlow, Martin, Mrak, Robert, Barger, Steven, Griffin, W.

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MOESM3 of Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site von Balasubramaniam, Meenakshisundaram, Parcon, Paul, Bose, Chhanda, Liu, Ling, Jones, Richard, Farlow, Martin, Mrak, Robert, Barger, Steven, Griffin, W.

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