Differential immune profiles distinguish the mutational subtypes of gastrointestinal stromal tumor von Vitiello, Gerardo A, Bowler, Timothy G, Liu, Mengyuan, Medina, Benjamin D, Zhang, Jennifer Q, Param, Nesteene J, Loo, Jennifer K, Goldfeder, Rachel L, Chibon, Frederic, Rossi, Ferdinand, Zeng, Shan, DeMatteo, Ronald P

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Mitochondrial Inhibition Augments the Efficacy of Imatinib by Resetting the Metabolic Phenotype of Gastrointestinal Stromal Tumor von Vitiello, Gerardo A, Medina, Benjamin D, Zeng, Shan, Bowler, Timothy G, Zhang, Jennifer Q, Loo, Jennifer K, Param, Nesteene J, Liu, Mengyuan, Moral, Alec J, Zhao, Julia N, Rossi, Ferdinand, Antonescu, Cristina R, Balachandran, Vinod P, Cross, Justin R, DeMatteo, Ronald P

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Myosin Light-Chain Kinase Inhibition Potentiates the Antitumor Effects of Avapritinib in PDGFRA D842V-Mutant Gastrointestinal Stromal Tumor von Rossi, Ferdinand, Liu, Mengyuan, Tieniber, Andrew, Etherington, Mark S, Hanna, Andrew, Vitiello, Gerardo A, Param, Nesteene J, Do, Kevin, Wang, Laura, Antonescu, Cristina R, Zeng, Shan, Zhang, Jennifer Q, DeMatteo, Ronald P

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Oncogenic kinase inhibition limits Batf3-dependent dendritic cell development and antitumor immunity von Medina, Benjamin D, Liu, Mengyuan, Vitiello, Gerardo A, Seifert, Adrian M, Zeng, Shan, Bowler, Timothy, Zhang, Jennifer Q, Cavnar, Michael J, Loo, Jennifer K, Param, Nesteene J, Maltbaek, Joanna H, Rossi, Ferdinand, Balachandran, Vinod, DeMatteo, Ronald P

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The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor von Zhang, Jennifer Q., Bosbach, Benedikt, Loo, Jennifer K., Vitiello, Gerardo A., Zeng, Shan, Seifert, Adrian M., Medina, Benjamin D., Param, Nesteene J., Maltbaek, Joanna H., Rossi, Ferdinand, Antonescu, Cristina R., Besmer, Peter, DeMatteo, Ronald P.

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Adeno-associated virus-mediated trastuzumab delivery to the central nervous system for human epidermal growth factor receptor 2+ brain metastasis von Werner, Marcela S., Aras, Shweta, Morgan, Ashleigh R., Roamer, Jillian, Param, Nesteene J., Olagbegi, Kanyin, Lamontagne, R. Jason, Greig, Jenny A., Wilson, James M.

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Macrophages and CD8 + T Cells Mediate the Antitumor Efficacy of Combined CD40 Ligation and Imatinib Therapy in Gastrointestinal Stromal Tumors von Zhang, Jennifer Q, Zeng, Shan, Vitiello, Gerardo A, Seifert, Adrian M, Medina, Benjamin D, Beckman, Michael J, Loo, Jennifer K, Santamaria-Barria, Juan, Maltbaek, Joanna H, Param, Nesteene J, Moral, John A, Zhao, Julia N, Balachandran, Vinod, Rossi, Ferdinand, Antonescu, Cristina R, DeMatteo, Ronald P

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Oncogenic KIT Modulates Type I IFN-Mediated Antitumor Immunity in GIST von Liu, Mengyuan, Etherington, Mark S., Hanna, Andrew, Medina, Benjamin D., Vitiello, Gerardo A., Bowler, Timothy G., Param, Nesteene J., Levin, Lillian, Rossi, Ferdinand, DeMatteo, Ronald P.

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ETV4 collaborates with Wnt/β-catenin signaling to alter cell cycle activity and promote tumor aggressiveness in gastrointestinal stromal tumor von Zeng, Shan, Seifert, Adrian M, Zhang, Jennifer Q, Kim, Teresa S, Bowler, Timothy G, Cavnar, Michael J, Medina, Benjamin D, Vitiello, Gerardo A, Rossi, Ferdinand, Loo, Jennifer K, Param, Nesteene J, DeMatteo, Ronald P

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Novel microenvironment-based classification of intrahepatic cholangiocarcinoma with therapeutic implications von Martin-Serrano, Miguel A, Kepecs, Benjamin, Torres-Martin, Miguel, Bramel, Emily R, Haber, Philipp K, Merritt, Elliot, Rialdi, Alexander, Param, Nesteene Joy, Maeda, Miho, Lindblad, Katherine E, Carter, James K, Barcena-Varela, Marina, Mazzaferro, Vincenzo, Schwartz, Myron, Affo, Silvia, Schwabe, Robert F, Villanueva, Augusto, Guccione, Ernesto, Friedman, Scott L, Lujambio, Amaia, Tocheva, Anna, Llovet, Josep M, Thung, Swan N, Tsankov, Alexander M, Sia, Daniela

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Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in PDGFRA D842V-mutant gastrointestinal stromal tumor von Rossi, Ferdinand, Liu, Mengyuan, Tieniber, Andrew, Etherington, Mark S., Hanna, Andrew, Vitiello, Gerardo A., Param, Nesteene J., Do, Kevin, Wang, Laura, Antonescu, Cristina R., Zeng, Shan, Zhang, Jennifer Q., DeMatteo, Ronald P.

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Multiple intratumoral sources of kit ligand promote gastrointestinal stromal tumor von Tieniber, Andrew D., Rossi, Ferdinando, Hanna, Andrew N., Liu, Marion, Etherington, Mark S., Loo, Jennifer K., Param, Nesteene, Zeng, Shan, Do, Kevin, Wang, Laura, DeMatteo, Ronald P.

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Abstract LB201: Optimizing adeno-associated viral vector-mediated delivery of trastuzumab to the central nervous system for the treatment of Her2 positive brain metastasis von Werner, Marcela Salazar, Aras, Shweta, Morgan, Ashleigh, Param, Nesteene J., Greig, Jenny, Wilson, James M.

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Oncogenic KIT modulates type I interferon–mediated antitumor immunity in GIST von Liu, Mengyuan, Etherington, Mark S., Hanna, Andrew, Medina, Benjamin D., Vitiello, Gerardo A., Bowler, Timothy G., Param, Nesteene J., Levin, Lillian, Rossi, Ferdinand, DeMatteo, Ronald P.

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Abstract B27: Kit inhibition decreases tumoral MHC class I expression in gastrointestinal stromal tumors through reduction of type I interferon signaling von Liu, Mengyuan, Medina, Benjamin D, Vitiello, Geraldo A, Etherington, Mark S, Param, Nesteene J., DiLolle, Mia E, Bowler, Timothy G., Rossi, Ferdinando, DeMatteo, Ronald P.

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