ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity von Alcalá, Sonia, Sancho, Patricia, Martinelli, Paola, Navarro, Diego, Pedrero, Coral, Martín-Hijano, Laura, Valle, Sandra, Earl, Julie, Rodríguez-Serrano, Macarena, Ruiz-Cañas, Laura, Rojas, Katerin, Carrato, Alfredo, García-Bermejo, Laura, Fernández-Moreno, Miguel Ángel, Hermann, Patrick C., Sainz, Bruno

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Emerging roles of mitochondrial proteases in neurodegeneration von Martinelli, Paola, Rugarli, Elena I.

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CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins von Gao, Jie, Schatton, Désirée, Martinelli, Paola, Hansen, Henriette, Pla-Martin, David, Barth, Esther, Becker, Christian, Altmueller, Janine, Frommolt, Peter, Sardiello, Marco, Rugarli, Elena I

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Loss of prohibitin membrane scaffolds impairs mitochondrial architecture and leads to tau hyperphosphorylation and neurodegeneration von Merkwirth, Carsten, Martinelli, Paola, Korwitz, Anne, Morbin, Michela, Brönneke, Hella S, Jordan, Sabine D, Rugarli, Elena I, Langer, Thomas

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The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression von Whissell, Gavin, Montagni, Elisa, Martinelli, Paola, Hernando-Momblona, Xavier, Sevillano, Marta, Jung, Peter, Cortina, Carme, Calon, Alexandre, Abuli, Anna, Castells, Antoni, Castellvi-Bel, Sergi, Nacht, Ana Silvina, Sancho, Elena, Stephan-Otto Attolini, Camille, Vicent, Guillermo P., Real, Francisco X., Batlle, Eduard

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Nicotine Promotes Initiation and Progression of KRAS-Induced Pancreatic Cancer via Gata6- Dependent Dedifferentiation of Acinar Cells in Mice von Hermann, Patrick C, Sancho, Patricia, Cañamero, Marta, Martinelli, Paola, Madriles, Francesc, Michl, Patrick, Gress, Thomas, de Pascual, Ricardo, Gandia, Luis, Guerra, Carmen, Barbacid, Mariano, Wagner, Martin, Vieira, Catarina R, Aicher, Alexandra, Real, Francisco X, Sainz, Bruno, Heeschen, Christopher

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NOTCH pathway inactivation promotes bladder cancer progression von Maraver, Antonio, Fernandez-Marcos, Pablo J, Cash, Timothy P, Mendez-Pertuz, Marinela, Dueñas, Marta, Maietta, Paolo, Martinelli, Paola, Muñoz-Martin, Maribel, Martínez-Fernández, Mónica, Cañamero, Marta, Roncador, Giovanna, Martinez-Torrecuadrada, Jorge L, Grivas, Dimitrios, de la Pompa, Jose Luis, Valencia, Alfonso, Paramio, Jesús M, Real, Francisco X, Serrano, Manuel

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Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells von Aksoy, Irène, Giudice, Vincent, Delahaye, Edwige, Wianny, Florence, Aubry, Maxime, Mure, Magali, Chen, Jiaxuan, Jauch, Ralf, Bogu, Gireesh K., Nolden, Tobias, Himmelbauer, Heinz, Xavier Doss, Michael, Sachinidis, Agapios, Schulz, Herbert, Hummel, Oliver, Martinelli, Paola, Hübner, Norbert, Stanton, Lawrence W., Real, Francisco X., Bourillot, Pierre-Yves, Savatier, Pierre

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The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver von Hruschka, Natascha, Kalisz, Mark, Subijana, Maria, Graña-Castro, Osvaldo, Del Cano-Ochoa, Francisco, Brunet, Laia Paré, Chernukhin, Igor, Sagrera, Ana, De Reynies, Aurelien, Kloesch, Bernhard, Chin, Suet-Feung, Burgués, Octavio, Andreu, David, Bermejo, Begoña, Cejalvo, Juan Miguel, Sutton, Joe, Caldas, Carlos, Ramón-Maiques, Santiago, Carroll, Jason S., Prat, Aleix, Real, Francisco X., Martinelli, Paola

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The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying von Wang, Shuaiyu, Jacquemyn, Julie, Murru, Sara, Martinelli, Paola, Barth, Esther, Langer, Thomas, Niessen, Carien M, Rugarli, Elena I

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GATA6 activates Wnt signaling in pancreatic cancer by negatively regulating the Wnt antagonist Dickkopf-1 von Zhong, Yi, Wang, Zheng, Fu, Baojin, Pan, Fan, Yachida, Shinichi, Dhara, Mousumi, Albesiano, Emilia, Li, Li, Naito, Yoshiki, Vilardell, Felip, Cummings, Christopher, Martinelli, Paola, Li, Ang, Yonescu, Raluca, Ma, Qingyong, Griffin, Constance A, Real, Francisco X, Iacobuzio-Donahue, Christine A

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Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant von COLOMBO, Emanuela, MARTINELLI, Paola, GIUSEPPE PELICCI, Pier, ZAMPONI, Raffaella, SHING, Danielle C, BONETTI, Paola, LUZI, Lucilla, VOLORIO, Sara, BERNARD, Loris, PRUNERI, Giancarlo, ALCALAY, Myriam

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The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures von Heeschen, Christopher, Hermann, Patrick C., Martinelli, Paola, Alcalá, Sonia, Sainz, Bruno

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NMR applications to find and progress TREX1 binders von Geist, Leonhard, Martinelli, Paola, Mohideen-Ali, Shereena, Werni, Patrick, Fischer, Gerhard, Fuchs, Julian E., Rumpel, Klaus, Mayer, Moriz

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Genetic interaction between the m-AAA protease isoenzymes reveals novel roles in cerebellar degeneration von Martinelli, Paola, La Mattina, Veronica, Bernacchia, Andrea, Magnoni, Raffaella, Cerri, Federica, Cox, Gregory, Quattrini, Angelo, Casari, Giorgio, Rugarli, Elena I.

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The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway von Martinelli, Paola, Bonetti, Paola, Sironi, Cristina, Pruneri, Giancarlo, Fumagalli, Caterina, Raviele, Paola Rafaniello, Volorio, Sara, Pileri, Stefano, Chiarle, Roberto, McDuff, Fiona Kate Elizabeth, Tusi, Betsabeh Khoramian, Turner, Suzanne D., Inghirami, Giorgio, Pelicci, Pier Giuseppe, Colombo, Emanuela

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The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver von Hruschka, Natascha, Andreu Martínez, David, Real, Francisco X, Martinelli, Paola

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GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer von Martinelli, Paola, Carrillo-de Santa Pau, Enrique, Cox, Trevor, Sainz, Bruno, Dusetti, Nelson, Greenhalf, William, Rinaldi, Lorenzo, Costello, Eithne, Ghaneh, Paula, Malats, Núria, Büchler, Markus, Pajic, Marina, Biankin, Andrew V, Iovanna, Juan, Neoptolemos, John, Real, Francisco X

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A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer von Kloesch, Bernhard, Ionasz, Vivien, Paliwal, Sumit, Hruschka, Natascha, Martinez de Villarreal, Jaime, Öllinger, Rupert, Mueller, Sebastian, Dienes, Hans Peter, Schindl, Martin, Gruber, Elisabeth S, Stift, Judith, Herndler-Brandstetter, Dietmar, Lomberk, Gwen A, Seidler, Barbara, Saur, Dieter, Rad, Roland, Urrutia, Raul A, Real, Francisco X, Martinelli, Paola

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One-Pot Synthesis of Cereblon Proteolysis Targeting Chimeras via Photoinduced C(sp2)–C(sp3) Cross Coupling and Amide Formation for Proteolysis Targeting Chimera Library Synthesis von Arndt, Christine M., Bitai, Jacqueline, Brunner, Jessica, Opatz, Till, Martinelli, Paola, Gollner, Andreas, Sokol, Kevin R., Krumb, Matthias

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