KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia von Malinowska-Ozdowy, K, Frech, C, Schönegger, A, Eckert, C, Cazzaniga, G, Stanulla, M, zur Stadt, U, Mecklenbräuker, A, Schuster, M, Kneidinger, D, von Stackelberg, A, Locatelli, F, Schrappe, M, Horstmann, M A, Attarbaschi, A, Bock, C, Mann, G, Haas, O A, Panzer-Grümayer, R

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CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia von Inthal, A, Zeitlhofer, P, Zeginigg, M, Morak, M, Grausenburger, R, Fronkova, E, Fahrner, B, Mann, G, Haas, O A, Panzer-Grümayer, R

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Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multi... von Flohr, T, Schrauder, A, Cazzaniga, G, Panzer-Grümayer, R, van der Velden, V, Fischer, S, Stanulla, M, Basso, G, Niggli, F K, Schäfer, B W, Sutton, R, Koehler, R, Zimmermann, M, Valsecchi, M G, Gadner, H, Masera, G, Schrappe, M, van Dongen, J J M, Biondi, A, Bartram, C R

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Blocking ETV6/RUNX1-induced MDM2 overexpression by Nutlin-3 reactivates p53 signaling in childhood leukemia von Kaindl, U, Morak, M, Portsmouth, C, Mecklenbräuker, A, Kauer, M, Zeginigg, M, Attarbaschi, A, Haas, O A, Panzer-Grümayer, R

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Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia von Ellinghaus, E, Stanulla, M, Richter, G, Ellinghaus, D, te Kronnie, G, Cario, G, Cazzaniga, G, Horstmann, M, Panzer Grümayer, R, Cavé, H, Trka, J, Cinek, O, Teigler-Schlegel, A, ElSharawy, A, Häsler, R, Nebel, A, Meissner, B, Bartram, T, Lescai, F, Franceschi, C, Giordan, M, Nürnberg, P, Heinzow, B, Zimmermann, M, Schreiber, S, Schrappe, M, Franke, A

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Monitoring minimal residual disease in children with high-risk relapses of acute lymphoblastic leukemia: prognostic relevance of early and late assessment von Eckert, C, Hagedorn, N, Sramkova, L, Mann, G, Panzer-Grümayer, R, Peters, C, Bourquin, J-P, Klingebiel, T, Borkhardt, A, Cario, G, Alten, J, Escherich, G, Astrahantseff, K, Seeger, K, Henze, G, von Stackelberg, A

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Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting von VAN DER VELDEN, V. H. J, PANZER-GRÜMAYER, E. R, BARTRAM, C. R, MASERA, G, BIONDI, A, VAN DONGEN, J. J. M, CAZZANIGA, G, FLOHR, T, SUTTON, R, SCHRAUDER, A, BASSO, G, SCHRAPPE, M, WIJKHUIJS, J. M, KONRAD, M

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Glucocorticoid-regulated microRNAs and mirtrons in acute lymphoblastic leukemia von Rainer, J, Ploner, C, Jesacher, S, Ploner, A, Eduardoff, M, Mansha, M, Wasim, M, Panzer-Grümayer, R, Trajanoski, Z, Niederegger, H, Kofler, R

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Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement von JANSEN, M. W. J. C, CORRAL, L, VALSECCHI, M. G, BASSO, G, BIONDI, A, PIETERS, R, VAN DONGEN, J. J. M, VAN DER VELDEN, V. H. J, PANZER-GRÜMAYER, R, SCHRAPPE, M, SCHRAUDER, A, MARSCHALEK, R, MEYER, C, DEN BOER, M. L, HOP, W. J. C

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ETV6 RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1 von Krapf, G, Kaindl, U, Kilbey, A, Fuka, G, Inthal, A, Joas, R, Mann, G, Neil, J C, Haas, O A, Panzer-Grümayer, E R

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Prognostic significance of minimal residual disease in infants with acute lymphoblastic leukemia treated within the Interfant-99 protocol von Van der Velden, V H J, Corral, L, Valsecchi, M G, Jansen, M W J C, De Lorenzo, P, Cazzaniga, G, Panzer-Grümayer, E R, Schrappe, M, Schrauder, A, Meyer, C, Marschalek, R, Nigro, L L, Metzler, M, Basso, G, Mann, G, Den Boer, M L, Biondi, A, Pieters, R, Van Dongen, J J M

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Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia von Vesely, C, Frech, C, Eckert, C, Cario, G, Mecklenbräuker, A, zur Stadt, U, Nebral, K, Kraler, F, Fischer, S, Attarbaschi, A, Schuster, M, Bock, C, Cavé, H, von Stackelberg, A, Schrappe, M, Horstmann, M A, Mann, G, Haas, O A, Panzer-Grümayer, R

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Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood von van Dongen, Jacques JM, Seriu, Taku, Panzer-Grümayer, E Renate, Biondi, Andrea, Pongers-Willemse, Marja J, Corral, Lilly, Stolz, Frank, Schrappe, Martin, Masera, Giuseppe, Kamps, Willem A, Gadner, Helmuth, van Wering, Elisabeth R, Ludwig, Wolf-Dieter, Basso, Giuseppe, de Bruijn, Marianne AC, Cazzaniga, Giovanni, Hettinger, Klaudia, van der Does-van den Berg, Anna, Hop, Wim CJ, Riehm, Hansjörg, Bartram, Claus R

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Acute lymphoblastic leukemia with t(4;11) in children 1 year and older: The 'big sister' of the infant disease? von MANN, G, CAZZANIJA, G, GADNER, H, VAN DONGEN, J. J. M, PANZER-GRÜMAYER, E. R, VAN DER VELDEN, V. H. J, FLOHR, T, CSINADY, E, PAGANIN, M, SCHRAUDER, A, DOHNAL, A. M, SCHRAPPE, M, BIONDI, A

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Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts von Fuka, G, Kantner, H-P, Grausenburger, R, Inthal, A, Bauer, E, Krapf, G, Kaindl, U, Kauer, M, Dworzak, M N, Stoiber, D, Haas, O A, Panzer-Grümayer, R

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Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin and T cell receptor gene rearrangements and TAL1 d... von PONGERS-WILLEMSE, M. J, SERIU, T, MIGUEL, J. F. S, VAN DONGEN, J. J. M, STOLZ, F, D'ANIELLO, E, GAMEIRO, P, PISA, P, GONZALEZ, M, BARTRAM, C. R, PANZER-GRÜMAYER, E. R, BIONDI, A

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A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin von Russell, L J, De Castro, D G, Griffiths, M, Telford, N, Bernard, O, Panzer-Grümayer, R, Heidenreich, O, Moorman, A V, Harrison, C J

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Chromosome 14 copy number-dependent IGH gene rearrangement patterns in high hyperdiploid childhood B-cell precursor ALL: implications for leukemia biology and minimal residual dise... von Csinady, E, van der Velden, V H J, Joas, R, Fischer, S, de Vries, J F, Beverloo, H B, König, M, Pötschger, U, van Dongen, J J M, Mann, G, Haas, O A, Panzer-Grümayer, E R

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Analysis of minimal residual disease by Ig TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data von VAN DER VELDEN, V. H. J, CAZZANIGA, G, CAYUELA, J. M, TRKA, J, ECKERT, C, FORONI, L, ZUR STADT, U, BELDJORD, K, RAFF, T, VAN DER SCHOOT, C. E, VAN DONGEN, J. J. M, SCHRAUDER, A, HANCOCK, J, BADER, P, PANZER-GRUMAYER, E. R, FLOHR, T, SUTTON, R, CAVE, H, MADSEN, H. O

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Molecular detection of minimal residual disease is a strong predictive factor of relapse in childhood B-lineage acute lymphoblastic leukemia with medium risk features. A case contr... von BIONDI, A, VALSECCHI, M. G, BARTRAM, C. R, VAN DONGEN, J. J. M, PANZER-GRÜMAYER, E. R, SERIU, T, D'ANIELLO, E, WILLEMSE, M. J, FASCHING, K, PANNUNZIO, A, GADNER, H, SCHRAPPE, M, KAMPS, W. A

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