Mechanism of β2AR regulation by an intracellular positive allosteric modulator von Liu, Xiangyu, Masoudi, Ali, Kahsai, Alem W, Li-Yin, Huang, Pani Biswaranjan, Staus, Dean P, Shim, Paul J, Hirata Kunio, Simhal, Rishabh K, Schwalb, Allison M, Rambarat, Paula K, Ahn Seungkirl, Lefkowitz, Robert J, Kobilka, Brian

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Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation von Staus, Dean P., Strachan, Ryan T., Manglik, Aashish, Pani, Biswaranjan, Kahsai, Alem W., Kim, Tae Hun, Wingler, Laura M., Ahn, Seungkirl, Chatterjee, Arnab, Masoudi, Ali, Kruse, Andrew C., Pardon, Els, Steyaert, Jan, Weis, William I., Prosser, R. Scott, Kobilka, Brian K., Costa, Tommaso, Lefkowitz, Robert J.

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Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9 von Luttrell, Louis M, Wang, Jialu, Plouffe, Bianca, Smith, Jeffrey S, Yamani, Lama, Kaur, Suneet, Jean-Charles, Pierre-Yves, Gauthier, Christophe, Lee, Mi-Hye, Pani, Biswaranjan, Kim, Jihee, Ahn, Seungkirl, Rajagopal, Sudarshan, Reiter, Eric, Bouvier, Michel, Shenoy, Sudha K, Laporte, Stéphane A, Rockman, Howard A, Lefkowitz, Robert J

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G protein–coupled receptor kinases (GRKs) orchestrate biased agonism at the β2-adrenergic receptor von Choi, Minjung, Staus, Dean P, Wingler, Laura M, Ahn Seungkirl, Pani Biswaranjan, Capel, William D, Lefkowitz, Robert J

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Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library von Ahn, Seungkirl, Kahsai, Alem W., Pani, Biswaranjan, Wang, Qin-Ting, Zhao, Shuai, Wall, Alissa L., Strachan, Ryan T., Staus, Dean P., Wingler, Laura M., Sun, Lillian D., Sinnaeve, Justine, Choi, Minjung, Cho, Ted, Xu, Thomas T., Hansen, Gwenn M., Burnett, Michael B., Lamerdin, Jane E., Bassoni, Daniel L., Gavino, Bryant J., Husemoen, Gitte, Olsen, Eva K., Franch, Thomas, Costanzi, Stefano, Chen, Xin, Lefkowitz, Robert J.

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How carvedilol does not activate β2-adrenoceptors von Lefkowitz, Robert J., Rockman, Howard A., Shim, Paul J., Liu, Samuel, Ahn, Seungkirl, Pani, Biswaranjan, Rajagopal, Sudarshan, Shenoy, Sudha K., Bouvier, Michel, Benovic, Jeffrey L., Liggett, Stephen B., Ruffolo, Robert R., Bristow, Michael R., Packer, Milton

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Lipid Rafts Determine Clustering of STIM1 in Endoplasmic Reticulum-Plasma Membrane Junctions and Regulation of Store-operated Ca2+ Entry (SOCE) von Pani, Biswaranjan, Ong, Hwei Ling, Liu, Xibao, Rauser, Kristina, Ambudkar, Indu S., Singh, Brij B.

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The TR (i)P to Ca²⁺ signaling just got STIMy: an update on STIM1 activated TRPC channels von Pani, Biswaranjan, Bollimuntha, Sunitha, Singh, Brij B

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Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1 von Pani, Biswaranjan, Ong, Hwei Ling, Brazer, So-ching W, Liu, Xibao, Rauser, Kristina, Singh, Brij B, Ambudkar, Indu S

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Attenuation of store-operated Ca²⁺ current impairs salivary gland fluid secretion in TRPC1(-/-) mice von Liu, Xibao, Cheng, Kwong Tai, Bandyopadhyay, Bidhan C, Pani, Biswaranjan, Dietrich, Alexander, Paria, Biman C, Swaim, William D, Beech, David, Yildrim, Eda, Singh, Brij B, Birnbaumer, Lutz, Ambudkar, Indu S

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Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1 von Pani, Biswaranjan, Liu, Xibao, Bollimuntha, Sunitha, Cheng, Kwong Tai, Niesman, Ingrid R, Zheng, Changyu, Achen, Virginia R, Patel, Hemal H, Ambudkar, Indu S, Singh, Brij B

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Helminth induced suppression of macrophage activation is correlated with inhibition of calcium channel activity von Chauhan, Arun, Sun, Yuyang, Pani, Biswaranjan, Quenumzangbe, Fredice, Sharma, Jyotika, Singh, Brij B, Mishra, Bibhuti B

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Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure von Liu, Xiangyu, Ahn, Seungkirl, Kahsai, Alem W., Meng, Kai-Cheng, Latorraca, Naomi R., Pani, Biswaranjan, Venkatakrishnan, A. J., Masoudi, Ali, Weis, William I., Dror, Ron O., Chen, Xin, Lefkowitz, Robert J., Kobilka, Brian K.

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Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor von Kahsai, Alem W, Wisler, James W, Lee, Jungmin, Ahn, Seungkirl, Cahill III, Thomas J, Dennison, S Moses, Staus, Dean P, Thomsen, Alex R B, Anasti, Kara M, Pani, Biswaranjan, Wingler, Laura M, Desai, Hemant, Bompiani, Kristin M, Strachan, Ryan T, Qin, Xiaoxia, Alam, S Munir, Sullenger, Bruce A, Lefkowitz, Robert J

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Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for T... von Pani, Biswaranjan, Cornatzer, Eric, Cornatzer, William, Shin, Dong-Min, Pittelkow, Mark R, Hovnanian, Alain, Ambudkar, Indu S, Singh, Brij B

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Allosteric activation of proto-oncogene kinase Src by GPCR–beta-arrestin complexes von Pakharukova, Natalia, Masoudi, Ali, Pani, Biswaranjan, Staus, Dean P., Lefkowitz, Robert J.

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Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE von Liu, Xibao, Ong, Hwei Ling, Pani, Biswaranjan, Johnson, Katherine, Swaim, William B, Singh, Brij, Ambudkar, Indu

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Lipid rafts/caveolae as microdomains of calcium signaling von Pani, Biswaranjan, Singh, Brij B

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GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling von Thomsen, Alex R.B., Plouffe, Bianca, Cahill, Thomas J., Shukla, Arun K., Tarrasch, Jeffrey T., Dosey, Annie M., Kahsai, Alem W., Strachan, Ryan T., Pani, Biswaranjan, Mahoney, Jacob P., Huang, Liyin, Breton, Billy, Heydenreich, Franziska M., Sunahara, Roger K., Skiniotis, Georgios, Bouvier, Michel, Lefkowitz, Robert J.

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Mechanism of intracellular allosteric β 2 AR antagonist revealed by X-ray crystal structure von Liu, Xiangyu, Ahn, Seungkirl, Kahsai, Alem W, Meng, Kai-Cheng, Latorraca, Naomi R, Pani, Biswaranjan, Venkatakrishnan, A J, Masoudi, Ali, Weis, William I, Dror, Ron O, Chen, Xin, Lefkowitz, Robert J, Kobilka, Brian K

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