Design evaluation of the fractured main landing gear of a BAE Jetstream SX-SKY aircraft von Chondrou, I. T, Mavrantonakis, G, Tsagarakis, N, Vergis, E, Pangalos, D, Chondros, T. G

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Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework von Cook, David, Brown, Dearg, Alexander, Robert, March, Ruth, Morgan, Paul, Satterthwaite, Gemma, Pangalos, Menelas N.

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Impact of a five-dimensional framework on R&D productivity at AstraZeneca von Morgan, Paul, Brown, Dean G., Lennard, Simon, Anderton, Mark J., Barrett, J. Carl, Eriksson, Ulf, Fidock, Mark, Hamrén, Bengt, Johnson, Anthony, March, Ruth E., Matcham, James, Mettetal, Jerome, Nicholls, David J., Platz, Stefan, Rees, Steve, Snowden, Michael A., Pangalos, Menelas N.

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Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine von Falsey, Ann R, Sobieszczyk, Magdalena E, Hirsch, Ian, Sproule, Stephanie, Robb, Merlin L, Corey, Lawrence, Neuzil, Kathleen M, Hahn, William, Hunt, Julie, Mulligan, Mark J, McEvoy, Charlene, DeJesus, Edwin, Hassman, Michael, Little, Susan J, Pahud, Barbara A, Durbin, Anna, Pickrell, Paul, Daar, Eric S, Bush, Larry, Solis, Joel, Carr, Quito Osuna, Oyedele, Temitope, Buchbinder, Susan, Cowden, Jessica, Vargas, Sergio L, Guerreros Benavides, Alfredo, Call, Robert, Keefer, Michael C, Kirkpatrick, Beth D, Pullman, John, Tong, Tina, Brewinski Isaacs, Margaret, Benkeser, David, Janes, Holly E, Nason, Martha C, Green, Justin A, Kelly, Elizabeth J, Maaske, Jill, Mueller, Nancy, Shoemaker, Kathryn, Takas, Therese, Marshall, Richard P, Pangalos, Menelas N, Villafana, Tonya, Gonzalez-Lopez, Antonio

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Rapamycin alleviates toxicity of different aggregate-prone proteins von Berger, Zdenek, Ravikumar, Brinda, Menzies, Fiona M., Oroz, Lourdes Garcia, Underwood, Benjamin R., Pangalos, Menelas N., Schmitt, Ina, Wullner, Ullrich, Evert, Bernd O., O'Kane, Cahir J., Rubinsztein, David C.

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Monoacylglycerol Lipase Activity Is a Critical Modulator of the Tone and Integrity of the Endocannabinoid System von Chanda, Pranab K., Gao, Ying, Mark, Lilly, Btesh, Joan, Strassle, Brian W., Lu, Peimin, Piesla, Michael J., Zhang, Mei-Yi, Bingham, Brendan, Uveges, Albert, Kowal, Dianne, Garbe, David, Kouranova, Evguenia V., Ring, Robert H., Bates, Brian, Pangalos, Menelas N., Kennedy, Jeffrey D., Whiteside, Garth T., Samad, Tarek A.

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Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for Prevention of Covid-19 von Levin, Myron J., Ustianowski, Andrew, De Wit, Stéphane, Launay, Odile, Avila, Miles, Templeton, Alison, Yuan, Yuan, Seegobin, Seth, Ellery, Adam, Levinson, Dennis J., Ambery, Philip, Arends, Rosalinda H., Beavon, Rohini, Dey, Kanika, Garbes, Pedro, Kelly, Elizabeth J., Koh, Gavin C.K.W., Near, Karen A., Padilla, Kelly W., Psachoulia, Konstantina, Sharbaugh, Audrey, Streicher, Katie, Pangalos, Menelas N., Esser, Mark T.

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Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease von Brown, Jon T, Chin, Jeannie, Leiser, Steven C, Pangalos, Menelas N, Randall, Andrew D

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Activation of estrogen receptor-β regulates hippocampal synaptic plasticity and improves memory von Liu, Feng, Day, Mark, Muñiz, Luis C, Bitran, Daniel, Arias, Robert, Revilla-Sanchez, Raquel, Grauer, Steve, Zhang, Guoming, Kelley, Cody, Pulito, Virginia, Sung, Amy, Mervis, Ronald F, Navarra, Rachel, Hirst, Warren D, Reinhart, Peter H, Marquis, Karen L, Moss, Stephen J, Pangalos, Menelas N, Brandon, Nicholas J

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Pioneering government-sponsored drug repositioning collaborations: progress and learning von Frail, Donald E., Brady, Madeleine, Escott, K. Jane, Holt, Alison, Sanganee, Hitesh J., Pangalos, Menelas N., Watkins, Chris, Wegner, Craig D.

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Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank von Szustakowski, Joseph D., Balasubramanian, Suganthi, Kvikstad, Erika, Khalid, Shareef, Bronson, Paola G., Sasson, Ariella, Wong, Emily, Liu, Daren, Wade Davis, J., Haefliger, Carolina, Katrina Loomis, A., Mikkilineni, Rajesh, Noh, Hyun Ji, Wadhawan, Samir, Bai, Xiaodong, Hawes, Alicia, Krasheninina, Olga, Ulloa, Ricardo, Lopez, Alex E., Smith, Erin N., Waring, Jeffrey F., Whelan, Christopher D., Tsai, Ellen A., Overton, John D., Salerno, William J., Jacob, Howard, Szalma, Sandor, Runz, Heiko, Hinkle, Gregory, Nioi, Paul, Petrovski, Slavé, Miller, Melissa R., Baras, Aris, Mitnaul, Lyndon J., Reid, Jeffrey G.

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Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease von Corbett, Brian F, Leiser, Steven C, Ling, Huai-Ping, Nagy, Reka, Breysse, Nathalie, Zhang, Xiaohong, Hazra, Anupam, Brown, Jon T, Randall, Andrew D, Wood, Andrew, Pangalos, Menelas N, Reinhart, Peter H, Chin, Jeannie

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A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner von Goncalves, Maria Beatriz, Suetterlin, Philipp, Yip, Ping, Molina-Holgado, Francisco, Walker, Deborah J., Oudin, Madeleine J., Zentar, Marc P., Pollard, Steven, Yáñez-Muñoz, Rafael J., Williams, Gareth, Walsh, Frank S., Pangalos, Menelas N., Doherty, Patrick

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The use of TaqMan RT-PCR assays for semiquantitative analysis of gene expression in CNS tissues and disease models von Medhurst, Andrew D, Harrison, David C, Read, Simon J, Campbell, Colin A, Robbins, Melanie J, Pangalos, Menelas N

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mRNA distribution analysis of human TRPC family in CNS and peripheral tissues von Riccio, Antonio, Medhurst, Andrew D, Mattei, Cesar, Kelsell, Rosemary E, Calver, Andrew R, Randall, Andrew D, Benham, Christopher D, Pangalos, Menelas N

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Molecular Cloning and Characterization of Two Novel Retinoic Acid-Inducible Orphan G-Protein-Coupled Receptors (GPRC5B and GPRC5C) von Robbins, M.J., Michalovich, D., Hill, J., Calver, A.R., Medhurst, A.D., Gloger, I., Sims, M., Middlemiss, D.N., Pangalos, M.N.

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Cloning and Functional Expression of Human Short TRP7, a Candidate Protein for Store-operated Ca2+ Influx von Riccio, Antonio, Mattei, Cesar, Kelsell, Rosemary E., Medhurst, Andrew D., Calver, Andrew R., Randall, Andrew D., Davis, John B., Benham, Christopher D., Pangalos, Menelas N.

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Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations von FISHER, Marc, FEUERSTEIN, Giora, HOWELLS, David W, HUM, Patricia D, KENT, Thomas A, SAVITZ, Sean I, LO, Eng H

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The LXR agonist TO901317 selectively lowers hippocampal A beta 42 and improves memory in the Tg2576 mouse model of Alzheimer's disease von Riddell, DR, Zhou, H, Comery, T A, Kouranova, E, Lo, C F, Warwick, H K, Ring, R H, Kirksey, Y, Aschmies, S, Xu, J, Kubek, K, Hirst, W D, Gonzales, C, Chen, Y, Murphy, E, Leonard, S, Vasylyev, D, Oganesian, A, Martone, R L, Pangalos, M N, Reinhart, PH, Jacobsen, J S

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Rare variant associations with plasma protein levels in the UK Biobank von Dhindsa, Ryan S., Burren, Oliver S., Sun, Benjamin B., Prins, Bram P., Matelska, Dorota, Wheeler, Eleanor, Mitchell, Jonathan, Oerton, Erin, Hristova, Ventzislava A., Smith, Katherine R., Carss, Keren, Wasilewski, Sebastian, Harper, Andrew R., Paul, Dirk S., Fabre, Margarete A., Runz, Heiko, Viollet, Coralie, Challis, Benjamin, Platt, Adam, Vitsios, Dimitrios, Ashley, Euan A., Whelan, Christopher D., Pangalos, Menelas N., Wang, Quanli, Petrovski, Slavé

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