The function of ORAOV1/LTO1, a gene that is overexpressed frequently in cancer: essential roles in the function and biogenesis of the ribosome von Zhai, C, li, Y, Mascarenhas, C, Lin, Q, Li, K, Vyrides, I, Grant, C M, Panaretou, B

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Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex von Pearl, Laurence H, Ali, Maruf M. U, Roe, S. Mark, Vaughan, Cara K, Meyer, Phillipe, Panaretou, Barry, Piper, Peter W, Prodromou, Chrisostomos

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Structural and Functional Analysis of the Middle Segment of Hsp90: Implications for ATP Hydrolysis and Client Protein and Cochaperone Interactions von Meyer, Philippe, Prodromou, Chrisostomos, Hu, Bin, Vaughan, Cara, Roe, S. Mark, Panaretou, Barry, Piper, Peter W., Pearl, Laurence H.

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Co-chaperone Regulation of Conformational Switching in the Hsp90 ATPase Cycle von Siligardi, Giuliano, Hu, Bin, Panaretou, Barry, Piper, Peter W, Pearl, Laurence H, Prodromou, Chrisostomos

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Activation of the ATPase Activity of Hsp90 by the Stress-Regulated Cochaperone Aha1 von Panaretou, Barry, Siligardi, Giuliano, Meyer, Philippe, Maloney, Alison, Sullivan, Janis K., Singh, Shradha, Millson, Stefan H., Clarke, Paul A., Naaby-Hansen, Soren, Stein, Rob, Cramer, Rainer, Mollapour, Mehdi, Workman, Paul, Piper, Peter W., Pearl, Laurence H., Prodromou, Chrisostomos

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The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37) von Roe, S Mark, Ali, Maruf M U, Meyer, Philippe, Vaughan, Cara K, Panaretou, Barry, Piper, Peter W, Prodromou, Chrisostomos, Pearl, Laurence H

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Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery von Meyer, Philippe, Prodromou, Chrisostomos, Liao, Chunyan, Hu, Bin, Mark Roe, S, Vaughan, Cara K, Vlasic, Ignacija, Panaretou, Barry, Piper, Peter W, Pearl, Laurence H

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Regulation of Hsp90 ATPase Activity by the Co-chaperone Cdc37p/p50 von Siligardi, Giuliano, Panaretou, Barry, Meyer, Philippe, Singh, Shradha, Woolfson, Derek N., Piper, Peter W., Pearl, Laurence H., Prodromou, Chrisostomos

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Increasing Saccharomyces cerevisiae stress resistance, through the overactivation of the heat shock response resulting from defects in the Hsp90 chaperone, does not extend replicat... von Harris, N, MacLean, M, Hatzianthis, K, Panaretou, B, Piper, P W

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Induction of major heat-shock proteins of Saccharomyces cerevisiae, including plasma membrane Hsp30, by ethanol levels above a critical threshold von Piper, P.W, Talreja, K, Panaretou, B, Moradas-Ferreira, P, Byrne, K, Praekelt, U.M, Meacock, P, Recnacq, M, Boucherie, H

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The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains von Prodromou, Chrisostomos, Panaretou, Barry, Chohan, Shahzad, Siligardi, Giuliano, O'Brien, Ronan, Ladbury, John E., Roe, S.Mark, Piper, Peter W., Pearl, Laurence H.

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ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo von Panaretou, B, Prodromou, C, Roe, S.M, O'Brien, R, Ladbury, J.E, Piper, P.W, Pearl, L.H

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Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery von Meyer, Philippe

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Bolaamphiphile analogues of 12-bis-THA Cl2 are potent antimicrobial therapeutics with distinct mechanisms of action against bacterial, mycobacterial, and fungal pathogens von Di Blasio, S, Clarke, M, Hind, CK, Asai, M, Laurence, L, Benvenuti, A, Hassan, M, Semenya, D, Man, DK-W, Horrocks, V, Manzo, G, Van Der Lith, S, Lam, C, Gentile, E, Annette, C, Bosse, J, Li, Y, Panaretou, B, Langford, PR, Robertson, BD, Lam, JKW, Sutton, JM, McArthur, M, Mason, AJ

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Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones von Prodromou, Chrisostomos, Siligardi, Giuliano, O'Brien, Ronan, Woolfson, Derek N., Regan, Lynne, Panaretou, Barry, Ladbury, John E., Piper, Peter W., Pearl, Laurence H.

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Isolation of Yeast Plasma Membranes von Panaretou, Barry, Piper, Peter

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Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex von Hu, Bin, Liao, Chunyan, Millson, Stefan H., Mollapour, Mehdi, Prodromou, Chrisostomos, Pearl, Laurence H., Piper, Peter W., Panaretou, Barry

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ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone invivo von Panaretou, B.

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Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90β, a property that can be exploited in screens... von Piper, Peter W., Panaretou, Barry, Millson, Stefan H., Trumana, Andrew, Mollapour, Mehdi, Pearl, Laurence H., Prodromou, Chrisostomos

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Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach von Millson, Stefan H., Truman, Andrew W., Wolfram, Francis, King, Victoria, Panaretou, Barry, Prodromou, Chrisostomos, Pearl, Laurence H., Piper, Peter W.

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