The age-dependent association of risk factors with pancreatic cancer von Yuan, C., Kim, J., Wang, Q.L., Lee, A.A., Babic, A., Amundadottir, L.T., Ardanaz, E., Arslan, A.A., Beane-Freeman, L.E., Bracci, P.M., Bueno-de-Mesquita, B., Du, M., Gallinger, S., Giles, G.G., Goodman, P.J., Katzke, V.A., Klein, A.P., Kooperberg, C., Kraft, P., Li, D., Malats, N., Marchand, L.L., McCullough, M.L., Milne, R.L., Neoptolemos, J.P., Perdomo, S., Petersen, G.M., Risch, H.A., Shu, X.O., Stolzenberg-Solomon, R.Z., Van Den Eeden, S.K., Visvanathan, K., White, E., Wolpin, B.M., Zheng, W., Amundadottir, L.T., Klein, A.P., Li, D., McCullough, M.L., Petersen, G.M., Risch, H.A., Stolzenberg-Solomon, R.Z., Perez, K., Ng, K., Giovannucci, E.L., Stampfer, M.J., Kraft, P., Wolpin, B.M.

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Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer von Walsh, Naomi, Zhang, Han, Hyland, Paula L, Yang, Qi, Mocci, Evelina, Zhang, Mingfeng, Childs, Erica J, Collins, Irene, Wang, Zhaoming, Arslan, Alan A, Beane-Freeman, Laura, Bracci, Paige M, Brennan, Paul, Canzian, Federico, Duell, Eric J, Gallinger, Steven, Giles, Graham G, Goggins, Michael, Goodman, Gary E, Goodman, Phyllis J, Hung, Rayjean J, Kooperberg, Charles, Kurtz, Robert C, Malats, Núria, LeMarchand, Loic, Neale, Rachel E, Olson, Sara H, Scelo, Ghislaine, Shu, Xiao O, Van Den Eeden, Stephen K, Visvanathan, Kala, White, Emily, Zheng, Wei, Albanes, Demetrius, Andreotti, Gabriella, Babic, Ana, Bamlet, William R, Berndt, Sonja I, Borgida, Ayelet, Boutron-Ruault, Marie-Christine, Brais, Lauren, Bueno-de-Mesquita, Bas, Buring, Julie, Chaffee, Kari G, Chanock, Stephen, Cleary, Sean, Cotterchio, Michelle, Foretova, Lenka, Fuchs, Charles, M Gaziano, J Michael, Giovannucci, Edward, Hackert, Thilo, Haiman, Christopher, Hartge, Patricia, Hasan, Manal, Helzlsouer, Kathy J, Herman, Joseph, Holcatova, Ivana, Holly, Elizabeth A, Hoover, Robert, Janout, Vladimir, Klein, Eric A, Laheru, Daniel, Lee, I-Min, Lu, Lingeng, Mannisto, Satu, Milne, Roger L, Oberg, Ann L, Orlow, Irene, Patel, Alpa V, Peters, Ulrike, Porta, Miquel, Real, Francisco X, Rothman, Nathaniel, Sesso, Howard D, Severi, Gianluca, Silverman, Debra, Strobel, Oliver, Sund, Malin, Thornquist, Mark D, Tobias, Geoffrey S, Wactawski-Wende, Jean, Wareham, Nick, Weiderpass, Elisabete, Wentzensen, Nicolas, Wheeler, William, Yu, Herbert, Zeleniuch-Jacquotte, Anne, Kraft, Peter, Li, Donghui, Jacobs, Eric J, Petersen, Gloria M, Wolpin, Brian M, Risch, Harvey A, Amundadottir, Laufey T, Yu, Kai, Klein, Alison P, Stolzenberg-Solomon, Rachael Z

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A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer von Jermusyk, Ashley, Zhong, Jun, Connelly, Katelyn E., Gordon, Naomi, Perera, Sumeth, Abdolalizadeh, Ehssan, Zhang, Tongwu, O’Brien, Aidan, Hoskins, Jason W., Collins, Irene, Eiser, Daina, Yuan, Chen, Albanes, Demetrius, Arslan, Alan A., Gurrea, Aurelio Barricarte, Beane-Freeman, Laura, Bracci, Paige M., Bueno-de-Mesquita, Bas, Buring, Julie, Canzian, Federico, Gallinger, Stephen, Gaziano, J. Michael, Giles, Graham G., Goodman, Phyllis J., Johansson, Mattias, Kooperberg, Charles, LeMarchand, Loic, Malats, Nuria, Neale, Rachel E., Panico, Salvatore, Peters, Ulrike, Real, Francisco X., Shu, Xiao-Ou, Sund, Malin, Thornquist, Marc, Tjønneland, Anne, Travis, Ruth C., Van Den Eeden, Stephen K., Visvanathan, Kala, Zheng, Wei, Kraft, Peter, Risch, Harvey A., Jacobs, Eric J., Li, Donghui, Du, Mengmeng, Stolzenberg-Solomon, Rachael Z., Klein, Alison P., Smith, Jill P., Wolpin, Brian M., Chanock, Stephen J., Shi, Jianxin, Petersen, Gloria M., Westlake, Christopher J., Amundadottir, Laufey T.

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Abstract 1213: Genome-wide interaction scan identifies gene by smoking interaction at 2q21.3 for pancreatic cancer risk von Kundu, Prosenjit, Mocci, Evelina, Wheeler, William, Amundadottir, Laufey T., Li, Donghui, Jacobs, Eric J., Petersen, Gloria M., Wolpin, Brian M., Risch, Harvey A., Kraft, Peter, Chatterjee, Nilanjan, Klein, Alison P., Stolzenberg-Solomon, Rachael Z.

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Genetic effects and modifiers of radiotherapy and chemotherapy on survival in pancreatic cancer von Zeng, Hongmei, Yu, Herbert, Lu, Lingeng, Jain, Dhanpat, Kidd, Mark S, Saif, M Wasif, Chanock, Stephen J, Hartge, Patricia, Risch, Harvey A

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Quantifying the Genetic Correlation between Multiple Cancer Types von Lindström, Sara, Finucane, Hilary, Bulik-Sullivan, Brendan, Schumacher, Fredrick R, Amos, Christopher I, Hung, Rayjean J, Rand, Kristin, Gruber, Stephen B, Conti, David, Permuth, Jennifer B, Lin, Hui-Yi, Goode, Ellen L, Sellers, Thomas A, Amundadottir, Laufey T, Stolzenberg-Solomon, Rachael, Klein, Alison, Petersen, Gloria, Risch, Harvey, Wolpin, Brian, Hsu, Li, Huyghe, Jeroen R, Chang-Claude, Jenny, Chan, Andrew, Berndt, Sonja, Eeles, Rosalind, Easton, Douglas, Haiman, Christopher A, Hunter, David J, Neale, Benjamin, Price, Alkes L, Kraft, Peter

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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 von Fang, Jun, Jia, Jinping, Makowski, Matthew, Xu, Mai, Wang, Zhaoming, Zhang, Tongwu, Hoskins, Jason W., Choi, Jiyeon, Han, Younghun, Zhang, Mingfeng, Thomas, Janelle, Kovacs, Michael, Collins, Irene, Dzyadyk, Marta, Thompson, Abbey, O'Neill, Maura, Das, Sudipto, Lan, Qi, Koster, Roelof, Stolzenberg-Solomon, Rachael S., Kraft, Peter, Wolpin, Brian M., Jansen, Pascal W. T. C., Olson, Sara, McGlynn, Katherine A., Kanetsky, Peter A., Chatterjee, Nilanjan, Barrett, Jennifer H., Dunning, Alison M., Taylor, John C., Newton-Bishop, Julia A., Bishop, D. Timothy, Andresson, Thorkell, Petersen, Gloria M., Amos, Christopher I., Iles, Mark M., Nathanson, Katherine L., Landi, Maria Teresa, Vermeulen, Michiel, Brown, Kevin M., Amundadottir, Laufey T.

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Relationship between ABO Blood Group Alleles and Pancreatic Cancer Is Modulated by Secretor (FUT2) Genotype, but Not Lewis Antigen (FUT3) Genotype von Kim, Jihye, Yuan, Chen, Amundadottir, Laufey T, Wolpin, Brian M, Klein, Alison P, Risch, Harvey A, Kraft, Peter

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Novel pancreatic cancer susceptibility loci discovered through genome-wide association studies von Canzian, Federico, Campa, Daniele, Obazee, Ofure, Rizzato, Cosmeri, Gazouli, Maria, Cavestro, Giulia Martina, Scarpa, Aldo, Moz, Stefania, Pezzilli, Raffaele, Mambrini, Andrea, Boggi, Ugo, Capurso, Gabriele, Archibugi, Livia, Bambi, Franco, Andriulli, Angelo, Soucek, Pavel, Vodicka, Pavel, Mohelnikova-Duchonova, Beatrice, Lovecek, Martin, Hackert, Thilo, Neoptolemos, John P., Strobel, Oliver, Vashist, Yogesh K., Izbicki, Jakob R., Kaaks, Rudolf, Brenner, Hermann, Hegyi, Peter, Busch, Olivier, Bueno-de-Mesquita, H. Bas, Peeters, Petra H.M., Malecka-Panas, Ewa, Jamroziak, Krzysztof, Kupcinskas, Juozas, Costello, Eithne, Khaw, Kay-Tee, Key, Timothy J., Stolzenberg-Solomon, Rachael, Wolpin, Brian, Klein, Alison P., Amundadottir, Laufey T.

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Abstract 5891: The age-dependent association of risk factors with pancreatic cancer von Yuan, Chen, Kim, Jihye, Wang, Qiao-Li, Lee, Alice A., Babic, Ana, Amundadottir, Laufey T., Klein, Alison P., Li, Donghui, McCullough, Marjorie L., Petersen, Gloria M., Risch, Harvey A., Stolzenberg-Solomon, Rachael Z., Perez, Kimberly, Ng, Kimmie, Giovannucci, Edward L., Stampfer, Meir J., Kraft, Peter, Wolpin, Brian M.

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Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies von Elliott, Katherine S, Zeggini, Eleftheria, McCarthy, Mark I, Gudmundsson, Julius, Sulem, Patrick, Stacey, Simon N, Thorlacius, Steinunn, Amundadottir, Laufey, Grönberg, Henrik, Xu, Jianfeng, Gaborieau, Valerie, Eeles, Rosalind A, Neal, David E, Donovan, Jenny L, Hamdy, Freddie C, Muir, Kenneth, Hwang, Shih-Jen, Spitz, Margaret R, Zanke, Brent, Carvajal-Carmona, Luis, Brown, Kevin M, Hayward, Nicholas K, Macgregor, Stuart, Tomlinson, Ian P M, Lemire, Mathieu, Amos, Christopher I, Murabito, Joanne M, Isaacs, William B, Easton, Douglas F, Brennan, Paul, Barkardottir, Rosa B, Gudbjartsson, Daniel F, Rafnar, Thorunn, Hunter, David J, Chanock, Stephen J, Stefansson, Kari, Ioannidis, John P A

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Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers von Zhang, Yan Dora, Hurson, Amber N., Zhang, Haoyu, Choudhury, Parichoy Pal, Easton, Douglas F., Milne, Roger L., Simard, Jacques, Hall, Per, Michailidou, Kyriaki, Dennis, Joe, Schmidt, Marjanka K., Chang-Claude, Jenny, Gharahkhani, Puya, Whiteman, David, Campbell, Peter T., Hoffmeister, Michael, Jenkins, Mark, Peters, Ulrike, Hsu, Li, Gruber, Stephen B., Casey, Graham, Schmit, Stephanie L., O’Mara, Tracy A., Spurdle, Amanda B., Thompson, Deborah J., Tomlinson, Ian, De Vivo, Immaculata, Landi, Maria Teresa, Law, Matthew H., Iles, Mark M., Demenais, Florence, Kumar, Rajiv, MacGregor, Stuart, Bishop, D. Timothy, Ward, Sarah V., Bondy, Melissa L., Houlston, Richard, Wiencke, John K., Melin, Beatrice, Barnholtz-Sloan, Jill, Kinnersley, Ben, Wrensch, Margaret R., Amos, Christopher I., Hung, Rayjean J., Brennan, Paul, McKay, James, Caporaso, Neil E., Berndt, Sonja I., Birmann, Brenda M., Camp, Nicola J., Kraft, Peter, Rothman, Nathaniel, Slager, Susan L., Berchuck, Andrew, Pharoah, Paul D. P., Sellers, Thomas A., Gayther, Simon A., Pearce, Celeste L., Goode, Ellen L., Schildkraut, Joellen M., Moysich, Kirsten B., Amundadottir, Laufey T., Jacobs, Eric J., Klein, Alison P., Petersen, Gloria M., Risch, Harvey A., Stolzenberg-Solomon, Rachel Z., Wolpin, Brian M., Li, Donghui, Eeles, Rosalind A., Haiman, Christopher A., Kote-Jarai, Zsofia, Schumacher, Fredrick R., Al Olama, Ali Amin, Purdue, Mark P., Scelo, Ghislaine, Dalgaard, Marlene D., Greene, Mark H., Grotmol, Tom, Kanetsky, Peter A., McGlynn, Katherine A., Nathanson, Katherine L., Turnbull, Clare, Wiklund, Fredrik, Chanock, Stephen J., Chatterjee, Nilanjan, Garcia-Closas, Montserrat

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Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data von Shi, Jianxin, Park, Ju-Hyun, Duan, Jubao, Berndt, Sonja T, Moy, Winton, Yu, Kai, Song, Lei, Wheeler, William, Hua, Xing, Silverman, Debra, Garcia-Closas, Montserrat, Hsiung, Chao Agnes, Figueroa, Jonine D, Cortessis, Victoria K, Malats, Núria, Karagas, Margaret R, Vineis, Paolo, Chang, I-Shou, Lin, Dongxin, Zhou, Baosen, Seow, Adeline, Matsuo, Keitaro, Hong, Yun-Chul, Caporaso, Neil E, Wolpin, Brian, Jacobs, Eric, Petersen, Gloria M, Klein, Alison P, Li, Donghui, Risch, Harvey, Sanders, Alan R, Hsu, Li, Schoen, Robert E, Brenner, Hermann, Stolzenberg-Solomon, Rachael, Gejman, Pablo, Lan, Qing, Rothman, Nathaniel, Amundadottir, Laufey T, Landi, Maria Teresa, Levinson, Douglas F, Chanock, Stephen J, Chatterjee, Nilanjan

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Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions von Lindström, Sara, Wang, Lu, Feng, Helian, Majumdar, Arunabha, Huo, Sijia, Macdonald, James, Harrison, Tabitha, Turman, Constance, Chen, Hongjie, Mancuso, Nicholas, Bammler, Theo, Gallinger, Steve, Gruber, Stephen B, Gunter, Marc J, Le Marchand, Loic, Moreno, Victor, Offit, Kenneth, De Vivo, Immaculata, O’Mara, Tracy A, Spurdle, Amanda B, Tomlinson, Ian, Fitzgerald, Rebecca, Gharahkhani, Puya, Gockel, Ines, Jankowski, Janusz, Macgregor, Stuart, Schumacher, Johannes, Barnholtz-Sloan, Jill, Bondy, Melissa L, Houlston, Richard S, Jenkins, Robert B, Melin, Beatrice, Wrensch, Margaret, Brennan, Paul, Christiani, David C, Johansson, Mattias, Mckay, James, Aldrich, Melinda C, Amos, Christopher I, Landi, Maria Teresa, Tardon, Adonina, Bishop, D Timothy, Demenais, Florence, Goldstein, Alisa M, Iles, Mark M, Kanetsky, Peter A, Law, Matthew H, Amundadottir, Laufey T, Stolzenberg-Solomon, Rachael, Wolpin, Brian M, Klein, Alison, Petersen, Gloria, Risch, Harvey, Chanock, Stephen J, Purdue, Mark P, Scelo, Ghislaine, Pharoah, Paul, Kar, Siddhartha, Hung, Rayjean J, Pasaniuc, Bogdan, Kraft, Peter

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The association between genetically elevated polyunsaturated fatty acids and risk of cancer von Haycock, Philip C., Burrows, Kimberley, Lemaitre, Rozenn N., Burgess, Stephen, Khankari, Nikhil K., Tsilidis, Konstantinos K., Gaunt, Tom R., Hemani, Gibran, Zheng, Jie, Truong, Therese, Birmann, Brenda M., OMara, Tracy, Spurdle, Amanda B., Iles, Mark M., Law, Matthew H., Slager, Susan L., Saberi Hosnijeh, Fatemeh, Mariosa, Daniela, Cotterchio, Michelle, Cerhan, James R., Peters, Ulrike, Enroth, Stefan, Gharahkhani, Puya, Williams, Ann C., Block, Robert C., Amos, Christopher I., Hung, Rayjean J., Zheng, Wei, Gunter, Marc J., Smith, George Davey, Relton, Caroline, Martin, Richard M., Tintle, Nathan, Cheng, Iona, Jenkins, Mark, Cornish, Alex J., Sud, Amit, Vijayakrishnan, Jayaram, Wrensch, Margaret, Johansson, Mattias, Norman, Aaron D., Klein, Alison, Clay-Gilmour, Alyssa, Franke, Andre, Ardisson Korat, Andres V., Wheeler, Bill, Nilsson, Björn, Smith, Caren, Heng, Chew-Kiat, Song, Ci, Riadi, David, Claus, Elizabeth B., Ellinghaus, Eva, Ostroumova, Evgenia, Hosnijeh, de Vathaire, Florent, Cugliari, Giovanni, Matullo, Giuseppe, Oi-Lin Ng, Irene, Passow, Jeanette E., Foo, Jia Nee, Han, Jiali, Liu, Jianjun, Barnholtz-Sloan, Jill, Schildkraut, Joellen M., Wiemels, Joseph L., Hemminki, Kari, Yang, Keming, Kiemeney, Lambertus A., Wu, Lang, Amundadottir, Laufey, Stern, Marc-Henri, Boutron, Marie-Christine, Iles, Mark Martin, Purdue, Mark P., Stanulla, Martin, Bondy, Melissa, Gaudet, Mia, Mobuchon, Lenha, Camp, Nicola J., Sham, Pak Chung, Guénel, Pascal, Brennan, Paul, Taylor, Philip R., Ostrom, Quinn, Stolzenberg-Solomon, Rachael, Dorajoo, Rajkumar, Houlston, Richard, Jenkins, Robert B., Diskin, Sharon, Berndt, Sonja I., Channock, Stephen J., Harrison, Tabitha, Galesloot, Tessel, Gyllensten, Ulf, Joseph, Vijai, Shi, Y., Yang, Wenjian, Lin, Yi, Van Den Eeden, Stephen K.

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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 von Fang, Jun, Jia, Jinping, Makowski, Matthew, Xu, Mai, Wang, Zhaoming, Zhang, Tongwu, Hoskins, Jason W, Carrera Álvarez, Cristina, PanScan Consortium, TRICL Consortium, GenoMEL Consortium

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Two-Sample Mendelian Randomization Analysis of Associations Between Periodontal Disease and Risk of Cancer von Corlin, Laura, Ruan, Mengyuan, Tsilidis, Konstantinos K, Bouras, Emmanouil, Yu, Yau-Hua, Stolzenberg-Solomon, Rachael, Klein, Alison P, Risch, Harvey A, Amos, Christopher I, Sakoda, Lori C, Vodička, Pavel, Rish, Pai K, Beck, James, Platz, Elizabeth A, Michaud, Dominique S

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The association between genetically elevated polyunsaturated fatty acids and risk of cancer von Haycock, Philip C, Borges, Maria Carolina, Burrows, Kimberley, Lemaitre, Rozenn N, Burgess, Stephen, Khankari, Nikhil K, Tsilidis, Konstantinos K, Gaunt, Tom R, Hemani, Gibran, Zheng, Jie, Truong, Therese, Birmann, Brenda M, OMara, Tracy, Spurdle, Amanda B, Iles, Mark M, Law, Matthew H, Slager, Susan L, Saberi Hosnijeh, Fatemeh, Mariosa, Daniela, Cotterchio, Michelle, Cerhan, James R, Peters, Ulrike, Enroth, Stefan, Gharahkhani, Puya, Le Marchand, Loic, Williams, Ann C, Block, Robert C, ACCC, CCFR-CORECT-GECCO, EPITHYR, InterLymph, MMAC, ECAC, ILCCO, PRACTICAL Consortium, PanScan, PanC4, Amos, Christopher I, Hung, Rayjean J, Zheng, Wei, Gunter, Marc J, Smith, George Davey, Relton, Caroline, Martin, Richard M, Fatty Acids in Cancer Mendelian Randomization Collaboration

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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 von Fang, Jun, Jia, Jinping, Makowski, Matthew, Xu, Mai, Wang, Zhaoming, Zhang, Tongwu, Hoskins, Jason W, Choi, Jiyeon, Han, Younghun, Zhang, Mingfeng, Thomas, Janelle, Kovacs, Michael, Collins, Irene, Dzyadyk, Marta, Thompson, Abbey, O'Neill, Maura, Das, Sudipto, Lan, Qi, Koster, Roelof, Stolzenberg-Solomon, Rachael S, Kraft, Peter, Wolpin, Brian M, Jansen, Pascal W T C, Olson, Sara H, McGlynn, Katherine A, Kanetsky, Peter A, Chatterjee, Nilanjan, Barrett, Jennifer H, Dunning, Alison M, Taylor, John C, Newton-Bishop, Julia A, Bishop, D. Timothy, Andresson, Thorkell, Petersen, Gloria M, Amos, Christopher I, Iles, Mark M, Nathanson, Katherine L, Landi, Maria Teresa, Vermeulen, Michiel, Brown, Kevin M, Amundadottir, Laufey T, PanScan Consortium, Peeters, P

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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 von Fang, Jun, Jia, Jinping, Makowski, Matthew, Xu, Mai, Wang, Zhaoming, Zhang, Tongwu, Hoskins, Jason W, Choi, Jiyeon, Han, Younghun, Zhang, Mingfeng, Thomas, Janelle, Kovacs, Michael, Collins, Irene, Dzyadyk, Marta, Thompson, Abbey, O'Neill, Maura, Das, Sudipto, Lan, Qi, Koster, Roelof, Stolzenberg-Solomon, Rachael S, Kraft, Peter, Wolpin, Brian M, Jansen, Pascal W T C, Olson, Sara H, McGlynn, Katherine A, Kanetsky, Peter A, Chatterjee, Nilanjan, Barrett, Jennifer H, Dunning, Alison M, Taylor, John C, Newton-Bishop, Julia A, Bishop, D. Timothy, Andresson, Thorkell, Petersen, Gloria M, Amos, Christopher I, Iles, Mark M, Nathanson, Katherine L, Landi, Maria Teresa, Vermeulen, Michiel, Brown, Kevin M, Amundadottir, Laufey T, PanScan Consortium, Peeters, P

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