Concise Review: Bullseye: Targeting Cancer Stem Cells to Improve the Treatment of Gliomas by Repurposing Disulfiram von Triscott, Joanna, Rose Pambid, Mary, Dunn, Sandra E.

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Abstract P3-10-10: PMD-026, a first-in-class oral p90 ribosomal S6 kinase (RSK) inhibitor for triple negative breast cancer (TNBC) von Dunn, Sandra E., Jayanthan, Aarthi, Huynh, My-my, Flahive, Erik, Pambid, Mary Rose, Dorr, Andrew, Los, Gerrit

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Abstract PS11-33: A first-in-human Phase 1/1b multicenter, open-label dose escalation study to assess safety and tolerability of PMD-026, a first-in-class oral RSK inhibitor, in me... von Beeram, Murali, Wang, Judy S., Chalasani, Pavani, Mina, Lida, Patnaik, Amita, Pambid, Mary Rose, Jayanthan, Aarthi, Huynh, My-my, Los, Gerrit, Dunn, Sandra E., Dorr, F. Andrew

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YB‐1 Transforms Human Mammary Epithelial Cells Through Chromatin Remodeling Leading to the Development of Basal‐Like Breast Cancer von Davies, Alastair H., Reipas, Kristen M., Pambid, Mary Rose, Berns, Rachel, Stratford, Anna L., Fotovati, Abbas, Firmino, Natalie, Astanehe, Arezoo, Hu, Kaiji, Maxwell, Christopher, Mills, Gordon B., Dunn, Sandra E.

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Abstract 1038: PMD-026, a first in class oral RSK inhibitor, demonstrates synergy when combined with standard of care in breast cancer tumor models von Jayanthan, Aarthi, Huynh, My-my, Lee, Jangsoon, Los, Gerrit, Yue, Lambert, Pambid, Mary Rose, Ueno, Naoto T., Dunn, Sandra E.

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First-in-human phase I/Ib multicenter, open-label dose escalation study to assess safety and tolerability of PMD-026 in patients with metastatic breast cancer with expansion in met... von Beeram, Muralidhar, Wang, Judy Sing-Zan, Mina, Lida A., Patnaik, Amita, Pambid, Mary Rose, Jayanthan, Aarthi, Huynh, My-my, Dunn, Sandra Elaine, Los, Gerrit, Dorr, Andrew

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First-in-human phase 1/1b expansion of PMD-026, an oral RSK inhibitor, in patients with metastatic triple-negative breast cancer von Beeram, Muralidhar, Chalasani, Pavani, Wang, Judy S., Mina, Lida A., Shatsky, Rebecca Arielle, Trivedi, Meghna S., Wesolowski, Robert, Hurvitz, Sara A., Han, Hyo S., Patnaik, Amita, Pambid, Mary Rose, Jayanthan, Aarthi, Huynh, My-my, Los, Gerrit, Dunn, Sandra Elaine, Dorr, Andrew

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YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification von Davies, A H, Barrett, I, Pambid, M R, Hu, K, Stratford, A L, Freeman, S, Berquin, I M, Pelech, S, Hieter, P, Maxwell, C, Dunn, S E

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Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children von TRISCOTT, Joanna, LEE, Cathy, HAWKINS, Cynthia, RAMASWAMY, Vijay, BOUFFET, Eric, TAYLOR, Michael D, SINGHAL, Ash, HUKIN, Juliette, RASSEKH, Rod, YIP, Stephen, NORTHCOTT, Paul, SINGH, Sheila K, FOSTER, Colleen, DUNHAM, Christopher, DUNN, Sandra E, MANORANJAN, Branavan, PAMBID, Mary Rose, BERNS, Rachel, FOTOVATI, Abbas, VENUGOPAL, Chitra, O'HALLORAN, Katrina, NARENDRAN, Aru

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Abstract P5-17-12: First-in-human expansion study of oral PMD-026 in metastatic triple negative breast cancer patients von Beeram, Muralidhar, Wang, Judy S., Mina, Lida A., Chalasani, Pavani, Shatsky, Rebecca A., Wesolowski, Robert, Hurvitz, Sara A., Trivedi, Meghna S., Han, Hyo S., Patnaik, Amita, Huynh, My-my, Jayanthan, Aarthi, Pambid, Mary Rose, Yue, Lambert, Los, Gerrit, Dunn, Sandra E., Dorr, Andrew

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Overcoming resistance to sonic hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma von Pambid, Mary Rose, Berns, Rachel, Adomat, Hans H., Hu, Kaiji, Triscott, Joanna, Maurer, Norbert, Zisman, Natalia, Ramaswamy, Vijay, Hawkins, Cynthia E., Taylor, Michael D., Dunham, Christopher, Guns, Emma, Dunn, Sandra E.

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