The effect of patient-to-patient variability in drug response on combination cancer therapies, from 1961 to today von Palmer, Adam Christopher, Chabner, Bruce Allan, Sorger, Peter

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Guidance for Data Collection and Computational Modelling of Regulatory Networks von Palmer, Adam Christopher, Shearwin, Keith Edward

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Gene-Drug Interactions and the Evolution of Antibiotic Resistance von Palmer, Adam Christopher

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A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity von Palmer, Adam C, Chidley, Christopher, Sorger, Peter K

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Association analyses based on false discovery rate implicate new loci for coronary artery disease von Nelson, Christopher P, Goel, Anuj, Butterworth, Adam S, Kanoni, Stavroula, Webb, Tom R, Marouli, Eirini, Zeng, Lingyao, Ntalla, Ioanna, Lai, Florence Y, Hopewell, Jemma C, Giannakopoulou, Olga, Jiang, Tao, Hamby, Stephen E, Di Angelantonio, Emanuele, Assimes, Themistocles L, Bottinger, Erwin P, Chambers, John C, Clarke, Robert, Palmer, Colin N A, Cubbon, Richard M, Ellinor, Patrick, Ermel, Raili, Evangelou, Evangelos, Franks, Paul W, Grace, Christopher, Gu, Dongfeng, Hingorani, Aroon D, Howson, Joanna M M, Ingelsson, Erik, Kastrati, Adnan, Kessler, Thorsten, Kyriakou, Theodosios, Lehtimäki, Terho, Lu, Xiangfeng, Lu, Yingchang, März, Winfried, McPherson, Ruth, Metspalu, Andres, Pujades-Rodriguez, Mar, Ruusalepp, Arno, Schadt, Eric E, Schmidt, Amand F, Sweeting, Michael J, Zalloua, Pierre A, AlGhalayini, Kamal, Keavney, Bernard D, Kooner, Jaspal S, Loos, Ruth J F, Patel, Riyaz S, Rutter, Martin K, Tomaszewski, Maciej, Tzoulaki, Ioanna, Zeggini, Eleftheria, Erdmann, Jeanette, Dedoussis, George, Björkegren, Johan L M, Schunkert, Heribert, Farrall, Martin, Danesh, John, Samani, Nilesh J, Watkins, Hugh, Deloukas, Panos

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Phase 1 Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma Patients With Brain Metastases von Williams, Noelle L., Wuthrick, Evan J., Kim, Hyun, Palmer, Joshua D., Garg, Shivank, Eldredge-Hindy, Harriet, Daskalakis, Constantine, Feeney, Kendra J., Mastrangelo, Michael J., Kim, Lyndon J., Sato, Takami, Kendra, Kari L., Olencki, Thomas, Liebner, David A., Farrell, Christopher J., Evans, James J., Judy, Kevin D., Andrews, David W., Dicker, Adam P., Werner-Wasik, Maria, Shi, Wenyin

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A reference map of potential determinants for the human serum metabolome von Bar, Noam, Korem, Tal, Weissbrod, Omer, Zeevi, David, Rothschild, Daphna, Leviatan, Sigal, Kosower, Noa, Lotan-Pompan, Maya, Weinberger, Adina, Le Roy, Caroline I., Menni, Cristina, Visconti, Alessia, Falchi, Mario, Spector, Tim D., Adamski, Jerzy, Franks, Paul W., Pedersen, Oluf, Segal, Eran

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Aflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema von Wells, John A, Glassman, Adam R, Ayala, Allison R, Jampol, Lee M, Aiello, Lloyd Paul, Antoszyk, Andrew N, Arnold-Bush, Bambi, Baker, Carl W, Bressler, Neil M, Browning, David J, Elman, Michael J, Ferris, Frederick L, Friedman, Scott M, Melia, Michele, Pieramici, Dante J, Sun, Jennifer K, Beck, Roy W

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The genetic architecture of type 2 diabetes von Gaulton, Kyle J., McCarthy, Davis J., Sim, Xueling, Rayner, N. William, Cingolani, Pablo, Hartl, Christopher, Pearson, Richard D., Grarup, Niels, Chen, Yuhui, Chen, Peng, Go, Min Jin, Parker, Stephen C. J., Varga, Tibor V., Hu, Cheng, Kim, Bong-Jo, Kim, Yongkang, Kim, Young Jin, Maxwell, Taylor J., Nagai, Yoshihiko, Zhang, Weihua, Barzilai, Nir, Han, Bok-Ghee, Stančáková, Alena, Abboud, Hanna E., Boeing, Heiner, Prabhakaran, Dorairaj, Butterworth, Adam S., Lee, Heung Man, Kwak, Soo-Heon, Zhao, Wei, So, Wing Yee, Cheng, Ching-Yu, Curran, Joanne E., Freedman, Barry I., Kumar, Satish, van der Schouw, Yvonne T., Loh, Marie, Musani, Solomon K., Tan, Sian-Tsung, Taylor Jr, Herman A., Levy, Jonathan C., Mangino, Massimo, Bonnycastle, Lori L., Fadista, João, Surdulescu, Gabriela L., Herder, Christian, Groves, Christopher J., Brandslund, Ivan, Lyssenko, Valeriya, Hollensted, Mette, Jørgensen, Marit E., Ladenvall, Claes, Justesen, Johanne Marie, Linneberg, Allan, Qi, Qibin, Roden, Michael, Wood, Andrew R., Mihailov, Evelin, Maguire, Jared, Poplin, Ryan, Shakir, Khalid, Hrabé de Angelis, Martin, Jun, Goo, Murphy, Jacquelyn, Onofrio, Robert, Thorand, Barbara, Meisinger, Christa, Hu, Frank B., Peters, Annette, Rauramaa, Rainer, Salomaa, Veikko, Watanabe, Richard M., Bergman, Richard N., Bharadwaj, Dwaipayan, Chia, Kee Seng, Langenberg, Claudia, Elliott, Paul, Jablonski, Kathleen A., Ma, Ronald C. W., Tandon, Nikhil, Barroso, Inês, Zeggini, Eleftheria, Ried, Janina S., DeFronzo, Ralph A., Grallert, Harald, Banks, Eric, Trakalo, Joseph, Lind, Lars, Farjoun, Yossi, Owen, Katharine R., Gloyn, Anna L., Kooner, Jaspal Singh, Bowden, Donald W., Collins, Francis S., Atzmon, Gil, Hanis, Craig L., Seielstad, Mark, Frayling, Timothy M., Scott, Laura J., Altshuler, David

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Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease von Stitziel, Nathan O, Stirrups, Kathleen E, Masca, Nicholas G D, Erdmann, Jeanette, Ferrario, Paola G, König, Inke R, Weeke, Peter E, Webb, Thomas R, Auer, Paul L, Schick, Ursula M, Lu, Yingchang, Zhang, He, Dube, Marie-Pierre, Goel, Anuj, Farrall, Martin, Peloso, Gina M, Won, Hong-Hee, Do, Ron, van Iperen, Erik, Kanoni, Stavroula, Kruppa, Jochen, Mahajan, Anubha, Scott, Robert A, Willenberg, Christina, Braund, Peter S, van Capelleveen, Julian C, Doney, Alex S F, Donnelly, Louise A, Asselta, Rosanna, Merlini, Piera A, Duga, Stefano, Marziliano, Nicola, Denny, Josh C, Shaffer, Christian M, El-Mokhtari, Nour Eddine, Franke, Andre, Gottesman, Omri, Heilmann, Stefanie, Hengstenberg, Christian, Hoffman, Per, Holmen, Oddgeir L, Hveem, Kristian, Jansson, Jan-Håkan, Jöckel, Karl-Heinz, Kessler, Thorsten, Kriebel, Jennifer, Laugwitz, Karl L, Marouli, Eirini, Martinelli, Nicola, McCarthy, Mark I, Van Zuydam, Natalie R, Meisinger, Christa, Esko, Tõnu, Mihailov, Evelin, Escher, Stefan A, Alver, Maris, Moebus, Susanne, Morris, Andrew D, Müller-Nurasyid, Martina, Nikpay, Majid, Olivieri, Oliviero, Lemieux Perreault, Louis-Philippe, AlQarawi, Alaa, Robertson, Neil R, Akinsanya, Karen O, Reilly, Dermot F, Vogt, Thomas F, Yin, Wu, Asselbergs, Folkert W, Kooperberg, Charles, Jackson, Rebecca D, Stahl, Eli, Strauch, Konstantin, Varga, Tibor V, Waldenberger, Melanie, Zeng, Lingyao, Kraja, Aldi T, Liu, Chunyu, Ehret, George B, Newton-Cheh, Christopher, Chasman, Daniel I, Chowdhury, Rajiv, Ferrario, Marco, Ford, Ian, Jukema, J Wouter, Kee, Frank, Kuulasmaa, Kari, Nordestgaard, Børge G, Perola, Markus, Saleheen, Danish, Sattar, Naveed, Surendran, Praveen, Tregouet, David, Young, Robin, Howson, Joanna M M, Butterworth, Adam S, Danesh, John, Ardissino, Diego, Bottinger, Erwin P, Erbel, Raimund

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Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension von Surendran, Praveen, Drenos, Fotios, Witkowska, Kate, Tragante, Vinicius, Freitag, Daniel F, Tinker, Andrew, Harakalova, Magdalena, Rasheed, Asif, Bonnycastle, Lori L, Jackson, Anne U, Narisu, Narisu, Swift, Amy J, Ohlsson, Therese, Matchan, Angela, Stirrups, Kathleen E, Bork-Jensen, Jette, Gjesing, Anette P, Havulinna, Aki S, Zhang, He, Donnelly, Louise A, Neville, Matt J, Robertson, Neil R, Yiorkas, Andrianos M, Herzig, Karl-Heinz, Zhang, Weihua, Trabetti, Elisabetta, Evangelou, Evangelos, Moayyeri, Alireza, Nelson, Christopher P, de Craen, Anton J M, Trompet, Stella, Scott, Robert A, Marioni, Riccardo, Farmaki, Aliki-Eleni, Hallmans, Göran, Hassinen, Maija, Burgess, Stephen, Uria-Nickelsen, Maria, Reilly, Dermot F, Vogt, Thomas F, Traylor, Matthew, Justice, Anne E, Marouli, Eirini, Uusitupa, Matti, Polasek, Ozren, Rudan, Igor, Rolandsson, Olov, Dedoussis, George, Starr, John M, Brown, Morris J, Sattar, Naveed, Packard, Chris J, Mägi, Reedik, Metspalu, Andres, de Boer, Rudolf A, van der Meer, Peter, van der Harst, Pim, Lind, Lars, de Bakker, Paul I W, Korpi-Hyövälti, Eeva, Oksa, Heikki, Linneberg, Allan, Thuesen, Betina, Doney, Alex S F, Morris, Andrew D, Palmer, Colin N A, Holmen, Oddgeir Lingaas, Willer, Cristen J, Palotie, Aarno, Ripatti, Samuli, Majumder, Abdulla al Shafi, Chowdhury, Rajiv, Poulter, Neil, Sever, Peter, Amouyel, Philippe, Arveiler, Dominique, Blankenberg, Stefan, Ferrières, Jean, Müller-Nurasyid, Martina, Veronesi, Giovanni, Virtamo, Jarmo, Deloukas, Panos, Elliott, Paul, Melander, Olle, Kuusisto, Johanna, Laakso, Markku, Padmanabhan, Sandosh, Porteous, David J, Mohlke, Karen L, Pedersen, Oluf, Stringham, Heather M, Newton-Cheh, Christopher, Caulfield, Mark J, Morris, Andrew P, Tomaszewski, Maciej, Saleheen, Danish, Asselbergs, Folkert W, Wain, Louise V, Butterworth, Adam S, Howson, Joanna M M

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ICAR: endoscopic skull‐base surgery von Wang, Eric W., Zanation, Adam M., Gardner, Paul A., Schwartz, Theodore H., Eloy, Jean Anderson, Adappa, Nithin D., Bettag, Martin, Bleier, Benjamin S., Cappabianca, Paolo, Carrau, Ricardo L., Casiano, Roy R., Cavallo, Luigi M., Ebert, Charles S., El‐Sayed, Ivan H., Evans, James J., Fernandez‐Miranda, Juan C., Folbe, Adam J., Froelich, Sebastien, Gentili, Fred, Harvey, Richard J., Hwang, Peter H., Jane, John A., Kelly, Daniel F., Kennedy, David, Knosp, Engelbert, Lal, Devyani, Lee, John Y.K., Liu, James K., Lund, Valerie J., Palmer, James N., Prevedello, Daniel M., Schlosser, Rodney J., Sindwani, Raj, Solares, C. Arturo, Tabaee, Abtin, Teo, Charles, Thirumala, Parthasarathy D., Thorp, Brian D., Arnaldo Silva Vellutini, Eduardo, Witterick, Ian, Woodworth, Bradford A., Wormald, Peter‐John, Snyderman, Carl H.

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Biopolymer-supramolecular polymer hybrids for photocatalytic hydrogen production von Kupferberg, Jacob E, Syrgiannis, Zois, or evi, Luka, Bruckner, Eric P, Jaynes, Tyler J, Ha, Hakim H, Qi, Evan, Wek, Kristen S, Dannenhoffer, Adam J, Sather, Nicholas A, Fry, H. Christopher, Palmer, Liam C, Stupp, Samuel I

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Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England von Volz, Erik, Mishra, Swapnil, Chand, Meera, Barrett, Jeffrey C., Johnson, Robert, Geidelberg, Lily, Hinsley, Wes R., Laydon, Daniel J., Dabrera, Gavin, O’Toole, Áine, Amato, Robert, Ragonnet-Cronin, Manon, Harrison, Ian, Jackson, Ben, Ariani, Cristina V., Boyd, Olivia, Loman, Nicholas J., McCrone, John T., Gonçalves, Sónia, Jorgensen, David, Myers, Richard, Hill, Verity, Jackson, David K., Gaythorpe, Katy, Groves, Natalie, Sillitoe, John, Kwiatkowski, Dominic P., Flaxman, Seth, Ratmann, Oliver, Bhatt, Samir, Hopkins, Susan, Gandy, Axel, Rambaut, Andrew, Ferguson, Neil M.

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Risks of and risk factors for COVID-19 disease in people with diabetes: a cohort study of the total population of Scotland von McGurnaghan, Stuart J, Weir, Amanda, Bishop, Jen, Kennedy, Sharon, Blackbourn, Luke A K, McAllister, David A, Hutchinson, Sharon, Caparrotta, Thomas M, Mellor, Joseph, Jeyam, Anita, O'Reilly, Joseph E, Wild, Sarah H, Hatam, Sara, Höhn, Andreas, Colombo, Marco, Robertson, Chris, Lone, Nazir, Murray, Janet, Butterly, Elaine, Petrie, John, Kennon, Brian, McCrimmon, Rory, Lindsay, Robert, Pearson, Ewan, Sattar, Naveed, McKnight, John, Philip, Sam, Collier, Andrew, McMenamin, Jim, Smith-Palmer, Alison, Goldberg, David, McKeigue, Paul M, Colhoun, Helen M, Whettlock, Alice, McLeod, Allan, Gasiorowski, Andrew, Merrick, Andrew, McAuley, Andy, Went, April, Purdie, Calum, Fischbacher, Colin, Ramsey, Colin, Bailey, David, Henderson, David, McDonald, Eisin, Drennan, Genna, Gowans, Graeme, Reid, Graeme, Murdoch, Heather, Carruthers, Jade, Murray, Josie, Heatlie, Karen, Donaldson, Lorraine, Paton, Martin, Reid, Martin, Llano, Melissa, Murphy-Hall, Michelle, Hall, Ross, Cameron, Ross, Brownlie, Susan, Gaffney, Adam, Milne, Aynsley, Sullivan, Christopher, McArdle, Edward, Glass, Elaine, Young, Johanna, Malcolm, William, McCoubrey, Jodie

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Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus von Mahajan, Anubha, Sim, Xueling, Ng, Hui Jin, Manning, Alisa, Rivas, Manuel A, Highland, Heather M, Locke, Adam E, Grarup, Niels, Im, Hae Kyung, Cingolani, Pablo, Flannick, Jason, Fontanillas, Pierre, Fuchsberger, Christian, Gaulton, Kyle J, Teslovich, Tanya M, Rayner, N William, Robertson, Neil R, Beer, Nicola L, Rundle, Jana K, Bork-Jensen, Jette, Ladenvall, Claes, Blancher, Christine, Buck, David, Buck, Gemma, Burtt, Noël P, Gabriel, Stacey, Gjesing, Anette P, Groves, Christopher J, Hollensted, Mette, Huyghe, Jeroen R, Jackson, Anne U, Jun, Goo, Justesen, Johanne Marie, Mangino, Massimo, Murphy, Jacquelyn, Neville, Matt, Onofrio, Robert, Small, Kerrin S, Stringham, Heather M, Syvänen, Ann-Christine, Trakalo, Joseph, Abecasis, Goncalo, Bell, Graeme I, Blangero, John, Cox, Nancy J, Duggirala, Ravindranath, Hanis, Craig L, Seielstad, Mark, Wilson, James G, Christensen, Cramer, Brandslund, Ivan, Rauramaa, Rainer, Surdulescu, Gabriela L, Doney, Alex S F, Lannfelt, Lars, Linneberg, Allan, Isomaa, Bo, Tuomi, Tiinamaija, Jørgensen, Marit E, Jørgensen, Torben, Kuusisto, Johanna, Uusitupa, Matti, Salomaa, Veikko, Spector, Timothy D, Morris, Andrew D, Palmer, Colin N A, Collins, Francis S, Mohlke, Karen L, Bergman, Richard N, Ingelsson, Erik, Lind, Lars, Tuomilehto, Jaakko, Hansen, Torben, Watanabe, Richard M, Prokopenko, Inga, Dupuis, Josee, Karpe, Fredrik, Groop, Leif, Laakso, Markku, Pedersen, Oluf, Florez, Jose C, Morris, Andrew P, Altshuler, David, Meigs, James B, Boehnke, Michael, McCarthy, Mark I, Lindgren, Cecilia M, Gloyn, Anna L

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Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals von Ntalla, Ioanna, Karthikeyan, Savita, Mifsud, Borbala, Kraja, Aldi T., Cartwright, James H., Hellwege, Jacklyn N., Giri, Ayush, Tragante, Vinicius, Prins, Bram P., Cabrera, Claudia P., Eales, James M., Akbarov, Artur, Bielak, Lawrence F., Brody, Jennifer A., Drenos, Fotios, Nielsen, Sune Fallgaard, Faul, Jessica D., Franceschini, Nora, Gao, He, Giulianini, Franco, Hwang, Shih-Jen, Kanoni, Stavroula, Lindström, Jaana, Luan, Jian’an, Mahajan, Anubha, Malerba, Giovanni, Perola, Markus, Richard, Melissa, Richardson, Tom G., Sepúlveda, Nuno, Thériault, Sébastien, Trompet, Stella, Varga, Tibor V., Velez Edwards, Digna R., Veronesi, Giovanni, Weiss, Stefan, Willems, Sara M., Young, Robin, Zhang, Weihua, Zhao, Wei, Evangelou, Evangelos, Aeschbacher, Stefanie, Asllanaj, Eralda, Mutsert, Renée de, Dörr, Marcus, Gaziano, J. Michael, Have, Christian T., Kajantie, Eero, Kamat, Mihir, Karpe, Fredrik, Koistinen, Heikki A., Moitry, Marie, Peters, James, Rossouw, Jacques, Sever, Peter S., Sigurdsson, Emil L., Skaaby, Tea, Sun, Yan V., Trabetti, Elisabetta, Vaartjes, Ilonca, Buring, Julie E., Chowdhury, Rajiv, Correa, Adolfo, Deary, Ian J., Deloukas, Panos, Ferrières, Jean, Fornage, Myriam, Gaunt, Tom R., Harris, Tamara B., Järvelin, Marjo-Riitta, Kooperberg, Charles, Launer, Lenore J., Majumder, Abdulla al Shafi, Laakso, Markku, Melander, Olle, Mohlke, Karen L., Orho-Melander, Marju, Palmas, Walter, Polasek, Ozren, Province, Michael A., Rolandsson, Olov, Rosendaal, Frits R., Rotter, Jerome I., Samani, Nilesh J., Soranzo, Nicole, Spector, Timothy D., Starr, John M., van der Harst, Pim, van der Meer, Peter, Verweij, Niek, Virtamo, Jarmo, Wareham, Nicholas J., Langenberg, Claudia, Liu, Chunyu, Manning, Alisa K., Morrison, Alanna C., O’Donnell, Christopher J., Saleheen, Danish, Boerwinkle, Eric, Chasman, Daniel I.

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REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: protocol f... von Kendrick, Tony, Geraghty, Adam W A, Bowers, Hannah, Stuart, Beth, Leydon, Geraldine, May, Carl, Yao, Guiqing, O'Brien, Wendy, Glowacka, Marta, Holley, Simone, Williams, Samantha, Zhu, Shihua, Dewar-Haggart, Rachel, Palmer, Bryan, Bell, Margaret, Collinson, Sue, Fry, Imogen, Lewis, Glyn, Griffiths, Gareth, Gilbody, Simon, Moncrieff, Joanna, Moore, Michael, Macleod, Una, Little, Paul, Dowrick, Christopher

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Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies von Furness, Andrew J.S., Joshi, Kroopa, Rosenthal, Rachel, Ghorani, Ehsan, Spain, Lavinia, Ben Aissa, Assma, Smith, Myles, Strauss, Dirk, Hayes, Andrew, Nicol, David, Mårtensson, Linda, Harrington, Kevin, Wotherspoon, Andrew, Fernando, Archana, Chandra, Ashish, Rudman, Sarah, Varia, Mary, Polson, Alexander, Stamp, Gordon, Hill, Peter, Olsburgh, Jonathan, Lester, Jason, Attanoos, Richard, Adams, Haydn, Shaw, Jacqui, Le Quesne, John, Marshall, Hilary, Nelson, Louise, Bennett, Jonathan, Martinson, Luke, Kerr, Keith, Miller, Joy, Naidu, Babu, Langman, Gerald, Bellamy, Mary, Summers, Yvonne, Shah, Rajesh, Rammohan, Kendadai, Booton, Richard, Moss, Stuart, Idries, Faiza, Joseph, Leena, Chaturvedi, Anshuman, Marie Quinn, Anne, Doran, Helen, Waddington, Rachael, Blackhall, Fiona, Rogan, Jane, Smith, Elaine, Dive, Caroline, Brady, Ged, Chemie, Francesca, Tugwood, Jonathan, Lawrence, David, Panagiotopoulos, Nikolaos, Falzon, Mary, Borg, Elaine, Jamal-Hanjani, Mariam, Juul Birkbak, Nicolai, McGranahan, Nicholas, Goldman, Jacki, Veeriah, Raju, Johnson, Diana, Oukrif, Dahmane, Janes, Sam, Hartley, John, Kevin Stone, Richard, Denner, Tamara, Costa, Marta, Phillimore, Ben, Nye, Emma, Elgar, Greg, Al-Bakir, Maise, Navani, Neal, Gorman, Pat, MacKenzie, Mairead, Bell, Harriet, Hackshaw, Allan, Smith, Sean, Shaw, Emily, Lim, Eric, Nicholson, Andrew, Rice, Alexandra, Carlo Ronquillo, John, Mensah, Natalie, Finch, Jonathan, Lau, Kelvin, Schmid, Peter, Conibear, John, Danson, Sarah, Bury, Jonathan, Hill, Jennifer, Shackcloth, Michael, Feeney, Sarah, Asante-Siaw, Julius, Blyth, Kevin, Kirk, Alan, Pule, Martin, Turajlic, Samra, Peggs, Karl S.

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Performance and selectivity of cationic nanoparticle pseudo‐stationary phases in electrokinetic chromatography von McGettrick, Julie R., Williamson, Nathan H., Sutton, Adam T., Palmer, Christopher P.

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