Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation von Sprüssel, A, Schulte, J H, Weber, S, Necke, M, Händschke, K, Thor, T, Pajtler, K W, Schramm, A, König, K, Diehl, L, Mestdagh, P, Vandesompele, J, Speleman, F, Jastrow, H, Heukamp, L C, Schüle, R, Dührsen, U, Buettner, R, Eggert, A, Göthert, J R

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Current recommendations for clinical surveillance and genetic testing in rhabdoid tumor predisposition: a report from the SIOPE Host Genome Working Group von Frühwald, M. C., Nemes, K., Boztug, H., Cornips, M. C. A., Evans, D. G., Farah, R., Glentis, S., Jorgensen, M., Katsibardi, K., Hirsch, S., Jahnukainen, K., Kventsel, I., Kerl, K., Kratz, C. P., Pajtler, K. W., Kordes, U., Ridola, V., Stutz, E., Bourdeaut, F.

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How we treat medulloblastoma in adults von Franceschi, E., Seidel, C., Sahm, F., Pajtler, K.W., Hau, P.

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Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas von Künkele, Annette, De Preter, Katleen, Heukamp, Lukas, Thor, Theresa, Pajtler, Kristian W, Hartmann, Wolfgang, Mittelbronn, Michel, Grotzer, Michael A, Deubzer, Hedwig E, Speleman, Frank, Schramm, Alexander, Eggert, Angelika, Schulte, Johannes H

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Liquid biopsies“ als neue Diagnostikplattform in der pädiatrischen Onkologie von Deubzer, H. E, Eggert, A, Pajtler, K. W

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Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort von Waszak, Sebastian M, Northcott, Paul A, Buchhalter, Ivo, Robinson, Giles W, Sutter, Christian, Groebner, Susanne, Grund, Kerstin B, Brugières, Laurence, Jones, David T W, Pajtler, Kristian W, Morrissy, A Sorana, Kool, Marcel, Sturm, Dominik, Chavez, Lukas, Ernst, Aurelie, Brabetz, Sebastian, Hain, Michael, Zichner, Thomas, Segura-Wang, Maia, Weischenfeldt, Joachim, Rausch, Tobias, Mardin, Balca R, Zhou, Xin, Baciu, Cristina, Lawerenz, Christian, Chan, Jennifer A, Varlet, Pascale, Guerrini-Rousseau, Lea, Fults, Daniel W, Grajkowska, Wiesława, Hauser, Peter, Jabado, Nada, Ra, Young-Shin, Zitterbart, Karel, Shringarpure, Suyash S, De La Vega, Francisco M, Bustamante, Carlos D, Ng, Ho-Keung, Perry, Arie, MacDonald, Tobey J, Hernáiz Driever, Pablo, Bendel, Anne E, Bowers, Daniel C, McCowage, Geoffrey, Chintagumpala, Murali M, Cohn, Richard, Hassall, Timothy, Fleischhack, Gudrun, Eggen, Tone, Wesenberg, Finn, Feychting, Maria, Lannering, Birgitta, Schüz, Joachim, Johansen, Christoffer, Andersen, Tina V, Röösli, Martin, Kuehni, Claudia E, Grotzer, Michael, Kjaerheim, Kristina, Monoranu, Camelia M, Archer, Tenley C, Duke, Elizabeth, Pomeroy, Scott L, Shelagh, Redmond, Frank, Stephan, Sumerauer, David, Scheurlen, Wolfram, Ryzhova, Marina V, Milde, Till, Kratz, Christian P, Samuel, David, Zhang, Jinghui, Solomon, David A, Marra, Marco, Eils, Roland, Bartram, Claus R, von Hoff, Katja, Rutkowski, Stefan, Ramaswamy, Vijay, Gilbertson, Richard J, Korshunov, Andrey, Taylor, Michael D, Lichter, Peter, Malkin, David, Gajjar, Amar, Korbel, Jan O, Pfister, Stefan M

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Germline Elongator mutations in Sonic Hedgehog medulloblastoma von Waszak, Sebastian M., Robinson, Giles W, Gudenas, Brian L., Smith, Kyle S., Forget, Antoine, Kojic, Marija, Garcia-Lopez, Jesus, Hadley, Jennifer, Hamilton, Kayla V., Indersie, Emilie, Buchhalter, Ivo, Kerssemakers, Jules, Jäger, Natalie, Sharma, Tanvi, Rausch, Tobias, Kool, Marcel, Sturm, Dominik, Jones, David T. W., Vasilyeva, Aksana, Tatevossian, Ruth G., Neale, Geoffrey, Lombard, Bérangère, Loew, Damarys, Nakitandwe, Joy, Rusch, Michael, Bowers, Daniel C., Bendel, Anne, Partap, Sonia, Chintagumpala, Murali, Crawford, John, Gottardo, Nicholas G., Smith, Amy, Dufour, Christelle, Rutkowski, Stefan, Eggen, Tone, Wesenberg, Finn, Kjaerheim, Kristina, Feychting, Maria, Lannering, Birgitta, Schüz, Joachim, Johansen, Christoffer, Andersen, Tina V., Röösli, Martin, Kuehni, Claudia E., Grotzer, Michael, Remke, Marc, Puget, Stéphanie, Pajtler, Kristian W., Milde, Till, Witt, Olaf, Ryzhova, Marina, Korshunov, Andrey, Orr, Brent A., Ellison, David W., Brugieres, Laurence, Lichter, Peter, Nichols, Kim E., Gajjar, Amar, Wainwright, Brandon J., Ayrault, Olivier, Korbel, Jan O., Northcott, Paul A., Pfister, Stefan M.

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P10.14.B PROGRESSION OF IDH-MUTANT ASTROCYTOMAS TO GRADE 4 UNDER TREATMENT-RELATED SELECTION PRESSURE von Rautajoki, K J, Jaatinen, S, Hartewig, A, Tiihonen, A M, Annala, M, Salonen, I, Valkonen, M, Simola, V, Vuorinen, E M, Kivinen, A, Rauhala, M J, Nurminen, R, Maass, K K, Lahtela, S, Jukkola, A, Yli-Harja, O, Helén, P, Pajtler, K W, Ruusuvuori, P, Haapasalo, J, Zhang, W, Haapasalo, H, Nykter, M

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Expression of NTRK1/TrkA affects immunogenicity of neuroblastoma cells von Pajtler, Kristian W., Rebmann, Vera, Lindemann, Monika, Schulte, Johannes H., Schulte, Stefanie, Stauder, Michael, Leuschner, Ivo, Schmid, Kurt‐Werner, Köhl, Ulrike, Schramm, Alexander, Eggert, Angelika

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Erratum to ‘How we treat medulloblastoma in adults’: [ESMO Open Volume 6, Issue 4, August 2021, 100173] von Franceschi, E., Seidel, C., Sahm, F., Pajtler, K.W., Hau, P.

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Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry... von Heipertz, AE, Pajtler, KW, Pfaff, E, Schramm, K, Blattner-Johnson, M, Milde, T, Jones, BC, Zuliani, C, Hutter, C, Lohi, O, Kattamis, A, Dachowska-Kalwak, I, Nilsson, A, Gerber, NU, Langenberg, KPS, Goemans, B, Zwaan, CM, Molenaar, JJ, Jager, N, Dirksen, U, Witt, R, Pfister, SM, Jones, DTW, Kopp-Schneider, A, Witt, O, van Tilburg, CM

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EP-03 MOLECULAR CLASSIFICATION OF EPENDYMAL TUMORS ACROSS ALL CNS COMPARTMENTS, HISTOPATHOLOGICAL GRADES AND AGE GROUPS von Pajtler, K. W., Witt, H., Sill, M., Jones, D., Hovestadt, V., Johann, P., Reimand, J., Lichter, P., Taylor, M. D., Gilbertson, R., Ellison, D. W., Aldape, K., Korshunov, A., Pfister, S. M., Kool, M.

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TOWARDS CLINICAL IMPLEMENTATION OF LIQUID BIOPSY ANALYSIS FOR PAEDIATRIC BRAIN TUMOUR PATIENTS - A PAN-EUROPEAN EFFORT FOR STANDARDIZATION von Simon, N, Maass, KK, Pokorna, P, Stepien, N, Rettenmeier, J, Saijonmaa, O, Fischer, TT, Senfter, D, Madlener, S, Giraud, G, Tham, E, Scarpini, CG, Murray, MJ, Hulleman, E, Clifford, SC, Pfister, SM, Pajtler, KW, Gojo, J

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Prophylactic surgery among germline TP53 mutation carriers in Germany – a multicentric observational study von Rippinger, N, Haun, MW, Fischer, C, Rhiem, K, Hübbel, A, Grill, S, Kiechle, M, Cremer, FW, Kast, K, Nguyen, HP, Ditsch, N, Kratz, P, Pfister, S, Pajtler, KW, Speiser, D, Seitz, S, Glimm, H, Maatouk, I, Hahne, A, Sutter, C, Schmutzler, RK, Dikow, N, Sohn, C, Schott, S

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Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines von Kocher, D, Cao, L, Guiho, R, Langhammer, M, Lai, YL, Becker, P, Hamdi, H, Friedel, D, Selt, F, Vonhören, D, Zaman, J, Valinciute, G, Herter, S, Picard, D, Rettenmeier, J, Maass, KK, Pajtler, KW, Remke, M, von Deimling, A, Pusch, S, Pfister, SM, Oehme, I, Jones, DTW, Halbach, S, Brummer, T, Martinez-Barbera, JP, Witt, O, Milde, T, Sigaud, R

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SIOP Ependymoma I: Final results, long term follow-up and molecular analysis of the trial cohort: A BIOMECA Consortium Study von Ritzmann, TA, Chapman, RJ, Kilday, J-P, Thorp, N, Modena, P, Dineen, RA, Macarthur, D, Mallucci, C, Jaspan, T, Pajtler, KW, Giagnacovo, M, Jacques, TS, Paine, SML, Ellison, DW, Bouffet, E, Grundy, RG, BIOMECA consortium

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Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors von Sievers, P, Henneken, SC, Blume, C, Sill, M, Schrimpf, D, Stichel, D, Okonechnikov, K, Reuss, DE, Benzel, J, Maass, KK, Kool, M, Sturm, D, Zheng, T, Ghasemi, DR, Kohlhof-Meinecke, P, Cruz, O, Sunol, M, Lavarino, C, Ruf, V, Boldt, HB, Pages, M, Pouget, C, Schweizer, L, Kranendonk, MEG, Akhtar, N, Bunkowski, S, Stadelmann, C, Schueller, U, Mueller, WC, Dohmen, H, Acker, T, Harter, PN, Mawrin, C, Beschorner, R, Brandner, S, Snuderl, M, Abdullaev, Z, Aldape, K, Gilbert, MR, Armstrong, TS, Ellison, DW, Capper, D, Ichimura, K, Reifenberger, G, Grundy, RG, Jabado, N, Krskova, L, Zapotocky, M, Vicha, A, Varlet, P, Wesseling, P, Rutkowski, S, Korshunov, A, Wick, W, Pfister, SM, Jones, DTW, von Deimling, A, Pajtler, KW, Sahm, F

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Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas von Zheng, T, Ghasemi, DR, Okonechnikov, K, Korshunov, A, Sill, M, Maass, KK, Benites Goncalves da Silva, P, Ryzhova, M, Gojo, J, Stichel, D, Arabzade, A, Kupp, R, Benzel, J, Taya, S, Adachi, T, Shiraishi, R, Gerber, NU, Sturm, D, Ecker, J, Sievers, P, Selt, F, Chapman, R, Haberler, C, Figarella-Branger, D, Reifenberger, G, Fleischhack, G, Rutkowski, S, Donson, AM, Ramaswamy, V, Capper, D, Ellison, DW, Herold-Mende, CC, Schuller, U, Brandner, S, Hernaiz Driever, P, Kros, JM, Snuderl, M, Milde, T, Grundy, RG, Hoshino, M, Mack, SC, Gilbertson, RJ, Jones, DTW, Kool, M, von Deimling, A, Pfister, SM, Sahm, F, Kawauchi, D, Pajtler, KW

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Sarcoma classification by DNA methylation profiling von Koelsche, C, Schrimpf, D, Stichel, D, Sill, M, Sahm, F, Reuss, DE, Blattner, M, Worst, B, Heilig, CE, Beck, K, Horak, P, Kreutzfeldt, S, Stark, S, Johann, P, Selt, F, Ecker, J, Pajtler, KW, Reinhardt, A, Sievers, P, Ebrahimi, A, Suwala, A, Fernández-Klett, F, Casalini, B, Hovestadt, V, Kommoss, FKF, Kriegsmann, M, Schick, M, Bewerunge-Hudler, M, Milde, T, Witt, O, Kool, M, Romero-Pérez, L, Grünewald, TGP, Kirchner, T, Wick, W, Platten, M, Uhl, M, Abdollahi, A, Debus, J, Lehner, B, Thomas, C, Hasselblatt, M, Hartmann, C, Staszewski, O, Prinz, M, Hench, J, Frank, S, Versleijen-Jonkers, YMH, Weidema, ME, Mentzel, T, Griewank, K, de Álava, E, Gastearena, MAI, Chang, KT-E, Low, SYY, Cuevas-Bourdier, A, Mittelbronn, M, Mynarek, M, Rutkowski, S, Schüller, U, Mautner, VF, Schittenhelm, J, Serrano, J, Snuderl, M, Büttner, R, Klingebiel, T, Buslei, R, Gessler, M, Wesseling, P, Dinjens, WNM, Jaunmuktane, Z, Lyskjær, I, Brors, B, Glimm, H, Heining, C, Tirado, OM, Sáinz-Jaspeado, M, Mora, J, Alonso, J, Del Muro, XG, Moran, S, Esteller, M, Benhamida, JK, Ladanyi, M, Wardelmann, E, Antonescu, C, Flanagan, A, Dirksen, U, Hohenberger, P, Baumhoer, D, Hartmann, W, Vokuhl, C, Flucke, U, Petersen, I, Mechtersheimer, G, Capper, D, Jones, DTW, Fröhling, S, Pfister, SM, von Deimling, A

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MYCN amplification drives an aggressive form of spinal ependymoma von Ghasemi, DR, Sill, M, Okonechnikov, K, Korshunov, A, Yip, S, Schutz, PW, Scheie, D, Kruse, A, Harter, PN, Kastelan, M, Wagner, M, Hartmann, C, Benzel, J, Maass, KK, Khasraw, M, Sträter, R, Thomas, C, Paulus, W, Kratz, CP, Witt, H, Kawauchi, D, Herold-Mende, C, Sahm, F, Brandner, S, Kool, M, Jones, DTW, von Deimling, A, Pfister, SM, Reuss, DE, Pajtler, KW

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