Supramolecular Iron Cylinder with Unprecedented DNA Binding Is a Potent Cytostatic and Apoptotic Agent without Exhibiting Genotoxicity von Hotze, Anna C.G., Hodges, Nikolas J., Hayden, Rachel E., Sanchez-Cano, Carlos, Paines, Christopher, Male, Natalia, Tse, Man-Kit, Bunce, Chris M., Chipman, J. Kevin, Hannon, Michael J.

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Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function von Woodruff, Prescott G, Barr, R. Graham, Bleecker, Eugene, Christenson, Stephanie A, Couper, David, Curtis, Jeffrey L, Gouskova, Natalia A, Hansel, Nadia N, Hoffman, Eric A, Kanner, Richard E, Kleerup, Eric, Lazarus, Stephen C, Martinez, Fernando J, Paine, Robert, Rennard, Stephen, Tashkin, Donald P, Han, MeiLan K

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Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS) von Couper, David, LaVange, Lisa M, Han, MeiLan, Barr, R Graham, Bleecker, Eugene, Hoffman, Eric A, Kanner, Richard, Kleerup, Eric, Martinez, Fernando J, Woodruff, Prescott G, Rennard, Stephen

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Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort von Hastie, Annette T, Martinez, Fernando J, Curtis, Jeffrey L, Doerschuk, Claire M, Hansel, Nadia N, Christenson, Stephanie, Putcha, Nirupama, Ortega, Victor E, Li, Xingnan, Barr, R Graham, Carretta, Elizabeth E, Couper, David J, Cooper, Christopher B, Hoffman, Eric A, Kanner, Richard E, Kleerup, Eric, O'Neal, Wanda K, Paine, Richard, Peters, Stephen P, Alexis, Neil E, Woodruff, Prescott G, Han, MeiLan K, Meyers, Deborah A, Bleecker, Eugene R, Alexis, Neil E, Anderson, Wayne H, Barr, R Graham, Bleecker, Eugene R, Boucher, Richard C, Bowler, Russell P, Carretta, Elizabeth E, Christenson, Stephanie A, Comellas, Alejandro P, Cooper, Christopher B, Couper, David J, Criner, Gerard J, Crystal, Ronald G, Curtis, Jeffrey L, Doerschuk, Claire M, Dransfield, Mark T, Freeman, Christine M, Han, MeiLan K, Hansel, Nadia N, Hastie, Annette T, Hoffman, Eric A, Kaner, Robert J, Kanner, Richard E, Kleerup, Eric C, Krishnan, Jerry A, LaVange, Lisa M, Lazarus, Stephen C, Martinez, Fernando J, Meyers, Deborah A, Newell, John D, Oelsner, Elizabeth C, O'Neal, Wanda K, Paine, Robert, Putcha, Nirupama, Rennard, Stephen I., Tashkin, Donald P, Scholand, Mary Beth, Wells, J Michael, Wise, Robert A, Woodruff, Prescott G

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Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort von Han, MeiLan K, Quibrera, Pedro M, Carretta, Elizabeth E, Barr, R Graham, Bleecker, Eugene R, Bowler, Russell P, Cooper, Christopher B, Comellas, Alejandro, Couper, David J, Curtis, Jeffrey L, Criner, Gerard, Dransfield, Mark T, Hansel, Nadia N, Hoffman, Eric A, Kanner, Richard E, Krishnan, Jerry A, Martinez, Carlos H, Pirozzi, Cheryl B, O'Neal, Wanda K, Rennard, Stephen, Tashkin, Donald P, Wedzicha, Jadwiga A, Woodruff, Prescott, Paine, Robert, Martinez, Fernando J, Alexis, Neil E, Anderson, Wayne H, Barr, R Graham, Bleecker, Eugene R, Boucher, Richard C, Bowler, Russell P, Carretta, Elizabeth E, Christenson, Stephanie A, Comellas, Alejandro P, Cooper, Christopher B, Couper, David J, Criner, Gerard J, Crystal, Ronald G, Curtis, Jeffrey L, Doerschuk, Claire M, Dransfield, Mark T, Freeman, Christine M, Han, MeiLan K, Hansel, Nadia N, Hastie, Annette T, Hoffman, Eric A, Kaner, Robert J, Kanner, Richard E, Kleerup, Eric C, Krishnan, Jerry A, LaVange, Lisa M, Lazarus, Stephen C, Martinez, Fernando J, Meyers, Deborah A, Newell, John D, Oelsner, Elizabeth C, O'Neal, Wanda K, Paine, Robert, Putcha, Nirupama, Rennard, Stephen I., Tashkin, Donald P, Scholand, Mary Beth, Wells, J Michael, Wise, Robert A, Woodruff, Prescott G

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Mucin Concentrations and Peripheral Airway Obstruction in Chronic Obstructive Pulmonary Disease von Kesimer, Mehmet, Smith, Benjamin M, Ceppe, Agathe, Ford, Amina A, Anderson, Wayne H, Barr, R Graham, O'Neal, Wanda K, Boucher, Richard C

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Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in COPD von Esther, Charles R., O’Neal, Wanda K., Anderson, Wayne H., Kesimer, Mehmet, Ceppe, Agathe, Doerschuk, Claire M., Alexis, Neil E., Hastie, Annette T., Barr, R. Graham, Bowler, Russell P., Wells, J. Michael, Oelsner, Elizabeth C., Comellas, Alejandro P., Tesfaigzi, Yohannes, Kim, Victor, Paulin, Laura M., Cooper, Christopher B., Han, MeiLan K., Huang, Yvonne J., Labaki, Wassim W., Curtis, Jeffrey L., Boucher, Richard C., Alexis, Neil E., Anderson, Wayne H., Arjomandi, Mehrdad, Barjaktarevic, Igor, Barr, R. Graham, Bateman, Lori A., Bhatt, Surya P., Bleecker, Eugene R., Boucher, Richard C., Bowler, Russell P., Christenson, Stephanie A., Comellas, Alejandro P., Cooper, Christopher B., Couper, David J., Criner, Gerard J., Crystal, Ronald G., Curtis, Jeffrey L., Doerschuk, Claire M., Dransfield, Mark T., Drummond, Brad, Freeman, Christine M., Galban, Craig, Han, MeiLan K., Hansel, Nadia N., Hastie, Annette T., Hoffman, Eric A., Huang, Yvonne, Kaner, Robert J., Kanner, Richard E., Kleerup, Eric C., Krishnan, Jerry A., LaVange, Lisa M., Lazarus, Stephen C., Martinez, Fernando J., Meyers, Deborah A., Moore, Wendy C., Newell, John D., Paine, Robert, Paulin, Laura, Peters, Stephen P., Pirozzi, Cheryl, Putcha, Nirupama, Oelsner, Elizabeth C., O’Neal, Wanda K., Ortega, Victor E., Raman, Sanjeev, Rennard, Stephen I., Tashkin, Donald P., Wells, J. Michael, Wise, Robert A., Woodruff, Prescott G.

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Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD: An Analysis of the SPIROMICS Cohort von Burkes, Robert M, Ceppe, Agathe S, Doerschuk, Claire M, Couper, David, Hoffman, Eric A, Comellas, Alejandro P, Barr, R Graham, Krishnan, Jerry A, Cooper, Christopher, Labaki, Wassim W, Ortega, Victor E, Wells, J Michael, Criner, Gerard J, Woodruff, Prescott G, Bowler, Russell P, Pirozzi, Cheryl S, Hansel, Nadia N, Wise, Robert A, Brown, Todd T, Drummond, M Bradley

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Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease von Motahari, Amin, Barr, R Graham, Han, MeiLan K, Anderson, Wayne H, Barjaktarevic, Igor, Bleecker, Eugene R, Comellas, Alejandro P, Cooper, Christopher B, Couper, David J, Hansel, Nadia N, Kanner, Richard E, Kazerooni, Ella A, Lynch, David A, Martinez, Fernando J, Newell, Jr, John D, Schroeder, Joyce D, Smith, Benjamin M, Woodruff, Prescott G, Hoffman, Eric A

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Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD von Fortis, Spyridon, Quibrera, Pedro M., Comellas, Alejandro P., Bhatt, Surya P., Tashkin, Donald P., Hoffman, Eric A., Criner, Gerard J., Han, MeiLan K., Barr, R. Graham, Arjomandi, Mehrdad, Dransfield, Mark B., Peters, Stephen P., Dolezal, Brett A., Kim, Victor, Putcha, Nirupama, Rennard, Stephen I., Paine, Robert, Kanner, Richard E., Curtis, Jeffrey L., Bowler, Russell P., Martinez, Fernando J., Hansel, Nadia N., Krishnan, Jerry A., Woodruff, Prescott G., Barjaktarevic, Igor Z., Couper, David, Anderson, Wayne H., Cooper, Christopher B., Alexis, Neil E., Anderson, Wayne H., Arjomandi, Mehrdad, Barjaktarevic, Igor, Barr, R. Graham, Basta, Patricia, Bateman, Lori A., Bhatt, Surya P., Bleecker, Eugene R., Boucher, Richard C., Bowler, Russell P., Christenson, Stephanie A., Comellas, Alejandro P., Cooper, Christopher B., Couper, David J., Criner, Gerard J., Crystal, Ronald G., Curtis, Jeffrey L., Doerschuk, Claire M., Dransfield, Mark T., Drummond, Brad, Freeman, Christine M., Galban, Craig, Han, MeiLan K., Hansel, Nadia N., Hastie, Annette T., Hoffman, Eric A., Huang, Yvonne, Kaner, Robert J., Kanner, Richard E., Kleerup, Eric C., Krishnan, Jerry A., LaVange, Lisa M., Lazarus, Stephen C., Martinez, Fernando J., Meyers, Deborah A., Moore, Wendy C., Newell, John D., Paine, Robert, Paulin, Laura, Peters, Stephen P., Pirozzi, Cheryl, Putcha, Nirupama, Oelsner, Elizabeth C., O’Neal, Wanda K., Ortega, Victor E., Raman, Sanjeev, Rennard, Stephen I., Tashkin, Donald P., Wells, J. Michael, Wise, Robert A., Woodruff, Prescott G.

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Aspirin Use and Respiratory Morbidity in COPD: A Propensity Score-Matched Analysis in Subpopulations and Intermediate Outcome Measures in COPD Study von Fawzy, Ashraf, Putcha, Nirupama, Aaron, Carrie P, Bowler, Russell P, Comellas, Alejandro P, Cooper, Christopher B, Dransfield, Mark T, Han, MeiLan K, Hoffman, Eric A, Kanner, Richard E, Krishnan, Jerry A, Labaki, Wassim W, Paine, 3rd, Robert, Paulin, Laura M, Peters, Stephen P, Wise, Robert, Barr, R Graham, Hansel, Nadia N

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Heterogeneous burden of lung disease in smokers with borderline airflow obstruction von Pirozzi, Cheryl S, Gu, Tian, Quibrera, Pedro M, Carretta, Elizabeth E, Han, MeiLan K, Murray, Susan, Cooper, Christopher B, Tashkin, Donald P, Kleerup, Eric C, Barjaktarevic, Igor, Hoffman, Eric A, Martinez, Carlos H, Christenson, Stephanie A, Hansel, Nadia N, Graham Barr, R, Bleecker, Eugene R, Ortega, Victor E, Martinez, Fernando J, Kanner, Richard E, Paine, 3rd, Robert

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Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS von Putcha, Nirupama, Fawzy, Ashraf, Paul, Gabriel G, Lambert, Allison A, Psoter, Kevin J, Sidhaye, Venkataramana K, Woo, John, Wells, J Michael, Labaki, Wassim W, Doerschuk, Claire M, Kanner, Richard E, Han, MeiLan K, Martinez, Carlos, Paulin, Laura M, Martinez, Fernando J, Wise, Robert A, O'Neal, Wanda K, Barr, R Graham, Hansel, Nadia N

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Alignment of Inhaled Chronic Obstructive Pulmonary Disease Therapies with Published Strategies. Analysis of the Global Initiative for Chronic Obstructive Lung Disease Recommendatio... von Ghosh, Sohini, Anderson, Wayne H, Putcha, Nirupama, Han, Meilan K, Curtis, Jeffrey L, Criner, Gerard J, Dransfield, Mark T, Barr, R Graham, Krishnan, Jerry A, Lazarus, Stephen C, Cooper, Christopher B, Paine, 3rd, Robert, Peters, Stephen P, Hansel, Nadia N, Martinez, Fernando J, Drummond, M Bradley

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Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium von Kasela, Silva, Ortega, Victor E, Martorella, Molly, Garudadri, Suresh, Nguyen, Jenna, Ampleford, Elizabeth, Pasanen, Anu, Nerella, Srilaxmi, Buschur, Kristina L, Barjaktarevic, Igor Z, Barr, R Graham, Bleecker, Eugene R, Bowler, Russell P, Comellas, Alejandro P, Cooper, Christopher B, Couper, David J, Criner, Gerard J, Curtis, Jeffrey L, Han, MeiLan K, Hansel, Nadia N, Hoffman, Eric A, Kaner, Robert J, Krishnan, Jerry A, Martinez, Fernando J, McDonald, Merry-Lynn N, Meyers, Deborah A, Paine, 3rd, Robert, Peters, Stephen P, Castro, Mario, Denlinger, Loren C, Erzurum, Serpil C, Fahy, John V, Israel, Elliot, Jarjour, Nizar N, Levy, Bruce D, Li, Xingnan, Moore, Wendy C, Wenzel, Sally E, Zein, Joe, Langelier, Charles, Woodruff, Prescott G, Lappalainen, Tuuli, Christenson, Stephanie A

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Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort von Burkes, Robert M, Gassett, Amanda J, Ceppe, Agathe S, Anderson, Wayne, O'Neal, Wanda K, Woodruff, Prescott G, Krishnan, Jerry A, Barr, R Graham, Han, MeiLan K, Martinez, Fernando J, Comellas, Alejandro P, Lambert, Allison A, Kaufman, Joel D, Dransfield, Mark T, Wells, J Michael, Kanner, Richard E, Paine, 3rd, Robert, Bleecker, Eugene R, Paulin, Laura M, Hansel, Nadia N, Drummond, M Bradley

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Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort von Bhatt, Surya P, Nath, Hrudaya P, Kim, Young-Il, Ramachandran, Rekha, Watts, Jubal R, Terry, Nina L J, Sonavane, Sushil, Deshmane, Swati P, Woodruff, Prescott G, Oelsner, Elizabeth C, Bodduluri, Sandeep, Han, MeiLan K, Labaki, Wassim W, Michael Wells, J, Martinez, Fernando J, Barr, R Graham, Dransfield, Mark T

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Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts von Keene, Jason D, Jacobson, Sean, Kechris, Katerina, Kinney, Gregory L, Foreman, Marilyn G, Doerschuk, Claire M, Make, Barry J, Curtis, Jeffrey L, Rennard, Stephen I, Barr, R Graham, Bleecker, Eugene R, Kanner, Richard E, Kleerup, Eric C, Hansel, Nadia N, Woodruff, Prescott G, Han, MeiLan K, Paine, 3rd, Robert, Martinez, Fernando J, Bowler, Russell P, O'Neal, Wanda K

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Genome-wide association study of lung function and clinical implication in heavy smokers von Li, Xingnan, Ortega, Victor E, Ampleford, Elizabeth J, Graham Barr, R, Christenson, Stephanie A, Cooper, Christopher B, Couper, David, Dransfield, Mark T, Han, Mei Lan K, Hansel, Nadia N, Hoffman, Eric A, Kanner, Richard E, Kleerup, Eric C, Martinez, Fernando J, Paine, 3rd, Robert, Woodruff, Prescott G, Hawkins, Gregory A, Bleecker, Eugene R, Meyers, Deborah A

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The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS von Wells, J Michael, Xing, Dongqi, Viera, Liliana, Burkes, Robert M, Wu, Yixin, Bhatt, Surya P, Dransfield, Mark T, Couper, David J, O'Neal, Wanda, Hoffman, Eric A, Gaggar, Amit, Barjaktarevic, Igor, Curtis, Jeffrey L, Labaki, Wassim W, Han, Mei Lan K, Freeman, Christine M, Putcha, Nirupama, Schlange, Thomas, Blalock, J Edwin

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