Natural product fragment combination to performance-diverse pseudo-natural products von Grigalunas, Michael, Burhop, Annina, Zinken, Sarah, Pahl, Axel, Gally, José-Manuel, Wild, Niklas, Mantel, Yannik, Sievers, Sonja, Foley, Daniel J., Scheel, Rebecca, Strohmann, Carsten, Antonchick, Andrey P., Waldmann, Herbert

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Design, Synthesis, and Phenotypic Profiling of Pyrano‐Furo‐Pyridone Pseudo Natural Products von Christoforow, Andreas, Wilke, Julian, Binici, Aylin, Pahl, Axel, Ostermann, Claude, Sievers, Sonja, Waldmann, Herbert

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Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor von Foley, Daniel J., Zinken, Sarah, Corkery, Dale, Laraia, Luca, Pahl, Axel, Wu, Yao‐Wen, Waldmann, Herbert

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Phenyl Esters Are Potent Inhibitors of Caseinolytic Protease P and Reveal a Stereogenic Switch for Deoligomerization von Hackl, Mathias W, Lakemeyer, Markus, Dahmen, Maria, Glaser, Manuel, Pahl, Axel, Lorenz-Baath, Katrin, Menzel, Thomas, Sievers, Sonja, Böttcher, Thomas, Antes, Iris, Waldmann, Herbert, Sieber, Stephan A

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Exploring Natural Product Fragments for Drug and Probe Discovery von Pahl, Axel, Waldmann, Herbert, Kumar, Kamal

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Discovery of a Novel Pseudo‐Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling von Wang, Lin, Yilmaz, Furkan, Yildirim, Okan, Schölermann, Beate, Bag, Sukdev, Greiner, Luca, Pahl, Axel, Sievers, Sonja, Scheel, Rebecca, Strohmann, Carsten, Squire, Christopher, Foley, Daniel J., Ziegler, Slava, Grigalunas, Michael, Waldmann, Herbert

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Spacial ScoreA Comprehensive Topological Indicator for Small-Molecule Complexity von Krzyzanowski, Adrian, Pahl, Axel, Grigalunas, Michael, Waldmann, Herbert

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The Cell Painting Assay as a Screening Tool for the Discovery of Bioactivities in New Chemical Matter von Pahl, Axel, Sievers, Sonja

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Phenotypic profiling enables the targeted design of a novel pseudo-natural product class von Zinken, Sarah, Pahl, Axel, Grigalunas, Michael, Waldmann, Herbert

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Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds von Akbarzadeh, Mohammad, Deipenwisch, Ilka, Schoelermann, Beate, Pahl, Axel, Sievers, Sonja, Ziegler, Slava, Waldmann, Herbert

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Morphological Profiling Identifies a Common Mode of Action for Small Molecules with Different Targets von Schneidewind, Tabea, Brause, Alexandra, Pahl, Axel, Burhop, Annina, Mejuch, Tom, Sievers, Sonja, Waldmann, Herbert, Ziegler, Slava

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Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products von Liu, Jie, Cremosnik, Gregor S., Otte, Felix, Pahl, Axel, Sievers, Sonja, Strohmann, Carsten, Waldmann, Herbert

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Identification of lysosomotropism using explainable machine learning and morphological profiling cell painting data von Tandon, Aishvarya, Santura, Anna, Waldmann, Herbert, Pahl, Axel, Czodrowski, Paul

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Pseudonatural Products Occur Frequently in Biologically Relevant Compounds von Gally, José-Manuel, Pahl, Axel, Czodrowski, Paul, Waldmann, Herbert

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Morphological subprofile analysis for bioactivity annotation of small molecules von Pahl, Axel, Schölermann, Beate, Lampe, Philipp, Rusch, Marion, Dow, Mark, Hedberg, Christian, Nelson, Adam, Sievers, Sonja, Waldmann, Herbert, Ziegler, Slava

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Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone von Grigalunas, Michael, Patil, Sohan, Krzyzanowski, Adrian, Pahl, Axel, Flegel, Jana, Schölermann, Beate, Xie, Jianing, Sievers, Sonja, Ziegler, Slava, Waldmann, Herbert

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Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay von Rezaei Adariani, Soheila, Agne, Daya, Koska, Sandra, Burhop, Annina, Seitz, Carina, Warmers, Jens, Janning, Petra, Metz, Malte, Pahl, Axel, Sievers, Sonja, Waldmann, Herbert, Ziegler, Slava

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Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis von Schneidewind, Tabea, Brause, Alexandra, Schölermann, Beate, Sievers, Sonja, Pahl, Axel, Sankar, Muthukumar G., Winzker, Michael, Janning, Petra, Kumar, Kamal, Ziegler, Slava, Waldmann, Herbert

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Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3 von Ceballos, Javier, Schwalfenberg, Melanie, Karageorgis, George, Reckzeh, Elena S., Sievers, Sonja, Ostermann, Claude, Pahl, Axel, Sellstedt, Magnus, Nowacki, Jessica, Carnero Corrales, Marjorie A., Wilke, Julian, Laraia, Luca, Tschapalda, Kirsten, Metz, Malte, Sehr, Dominik A., Brand, Silke, Winklhofer, Konstanze, Janning, Petra, Ziegler, Slava, Waldmann, Herbert

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Scaffold Remodelling of Diazaspirotricycles Enables Synthesis of Diverse sp3‐Rich Compounds With Distinct Phenotypic Effects von Okolo, Ephraim A., Pahl, Axel, Sievers, Sonja, Pask, Christopher M., Nelson, Adam, Marsden, Stephen P.

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