Anti-CD3 Bi-Fab crosslinking of T cells enables their fratricide by activation induced cell death (AICD) and cytotoxicity von Pages, Diana Gil, Nelson, Alfreda, Wang, Liangyu, White, Tommi, Schrum, Adam, Cannon, John

Volltext

Evaluating potential toxicities of cancer immunotherapies using autoimmune animal models von Okpasuo, Onyekachi Juliet, Cattin-Roy, Alexis N, Karasseva, Natalia, Mahadevappa, Chandrashekara Puthanapura, Radhakrishnan, Vijay, Zaghouani, Habib, Pages, Diana Gil

Volltext

Dissecting molecular mechanisms underlying T cell co-potentiation when targeting the TCR/CD3 complex with anti-CD3 Fab fragments von Huynh, Hien T., Puthanapura, Chandrashekara Mahadevappa, Nelson, Alfreda D, Becher, Laura RE, Abergel, Megan, Hu, Shuang, Alarcon, Balbino, Schrum, Adam, Pages, Diana Gil

Volltext

Bivalent anti-CD3 Fab dimers drive T cells into a highly efficient fratricide with potential clinical application von Pages, Diana Gil, Nelson, Alfreda D, White, Tommi A, Schrum, Adam G

Volltext

Abstract 962: Testing T cell co-potentiation as an antitumor therapeutic strategy in humanized mouse models von Nelson, Alfreda D., Elsbernd, Laura, Schrum, Adam G., Pages, Diana Gil

Volltext

Affinity threshold conversion: the progressive differentiation checkpoint at which the TCRα/CD3δ signaling axis controls thymic positive selection von Canfield, Jenna M, Ferrer, Alejandro, Neier, Steven C, Wilton, Katelynn M, Stiles, Robert J, Davis, Tessa, Schrum, Adam G, Pages, Diana Gil

Volltext

Anti-CD3 Mono-Fab co-potentiates TCR antigen recognition in human T cells von Becher, Laura R, Nevala, Wendy, Sutor, Shari, Abergel, Megan, Hoffmann, Michele, Parks, Christopher, Pease, Larry R, Schrum, Adam G, Markovic, Svetomir N, Pages, Diana Gil

Volltext

Reevaluating the biochemical valency of native TCR/CD3 complexes isolated from T cells (IRM7P.708) von Reed, Brendan, Gil Pages, Diana, Palmer, Ed, Schrum, Adam

Volltext

Reconstitution of TCR/CD3 expression in B cell lymphoma to dissect the contribution of CD3 conformational change from downstream signaling events in the process of TCR/CD3 downregu... von Ferrer, Alejandro, Reed, Brendan, Schrum, Adam, Gil Pages, Diana

Volltext

A role for CD3 conformation in the preTCR/CD3 complex (P4428) von Hoffmann, Michele, Parks, Christopher, Gil Pages, Diana

Volltext

A monomeric fab fragment capable of inducing CD3 conformational change increases T cell receptor reactivity to poorly immunogenic antigens (TUM2P.1020) von Hoffmann, Michele, Parks, Christopher, Hansen, Michael, Rajagopalan, Govindarajan, Pease, Larry, Schrum, Adam, Gil Pages, Diana

Volltext

Alpha-beta T cell positive selection is enhanced by CD3-delta via a quantitative developmental signaling mechanism von Wilton, Katelynn Marie, Huseby, April M, Ferrer, Alejandro, Neier, Steven C, Hoffmann, Michele, Wettstein, Peter, Carmona, Eva M, Kappes, Dietmar, Pages, Diana Gil, Johnson, Aaron J, Limper, Andrew H, Schrum, Adam G

Volltext

Multiplex IP-FCM reveals network-scale protein-protein interaction differences between pro-immunogenic and pro-tolerogenic TCR signaling (P1130) von Smith, Stephen, Neier, Steven, Davis, Tessa, McCluskey, James, Burrows, Scott, Sicotte, Hughes, Gil-Pages, Diana, Pittelkow, Mark, Neuhauser, Claudia, Schrum, Adam

Volltext

COMPOSITIONS AND METHODS FOR CO-POTENTIATION OF CD3 TO TREAT A VIRAL INFECTION AND INCREASE THE IMMUNE RESPONSE AGAINST A VIRAL ANTIGEN von Gil-Pages, Diana, Schrum, Adam G

Volltext bestellen

Monovalent anti-CD3 adjuvants von Pages, Diana Gil, Schrum, Adam G

Volltext bestellen

MONOVALENT ANTI-CD3 ADJUVANTS von Pages, Diana Gil, Schrum, Adam G

Volltext bestellen

MONOVALENT ANTI-CD3 ADJUVANTS von Pages Diana Gil, Schrum Adam G

Volltext bestellen

MONOVALENT ANTI-CD3 ADJUVANTS von SCHRUM, Adam G, PAGES, Diana Gil

Volltext bestellen

MONOVALENT ANTI-CD3 ADJUVANTS von SCHRUM ADAM G, PAGES DIANA GIL

Volltext bestellen

ANTI-CD3 THERAPIES von SCHRUM, ADAM, G, PAGES, DIANA, GIL

Volltext bestellen