CYTOTOXICITY AND ANTITUMOR-ACTIVITY OF CARZELESIN, A PRODRUG CYCLOPROPYLPYRROLOINDOLE ANALOG von LI, LH, DEKONING, TF, KELLY, RC, KRUEGER, WC, MCGOVREN, JP, PADBURY, GE, PETZOLD, GL, WALLACE, TL, OUDING, RJ, PRAIRIE, MD, GEBHARD

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Equilibrium distribution of HIV antiviral drugs into human peripheral blood mononuclear cells (PBMC) is controlled by free drug concentration in the extracellular medium von Koeplinger, Kenneth A, Raub, Thomas J, Padbury, Guy E, Zhao, Zhiyang

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Structure-Based Design of Sulfonamide-Substituted Non-Peptidic HIV Protease Inhibitors von Skulnick, Harvey I, Johnson, Paul D, Howe, W. Jeffrey, Tomich, Paul K, Chong, Kong-Teck, Watenpaugh, Keith D, Janakiraman, Musiri N, Dolak, Lester A, McGrath, James P

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Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity von Zhao, Z, Koeplinger, K A, Padbury, G E, Hauer, M J, Bundy, G L, Banitt, L S, Schwartz, T M, Zimmermann, D C, Harbach, P R, Mayo, J K, Aaron, C S

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Contribution of serum protein association to discrepancy between the in vivo and in vitro UDS results for 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) von Zhao, Zhiyang, Koeplinger, Kenneth A, Padbury, Guy E, Aaron, Charles S, Harbach, Philip R, Mayo, Judy K, Mattes, William B, Bundy, Gordon L

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Species-dependent enantioselective pharmacokinetics of PNU-103017, a Pyrone HIV protease inhibitor von Zhong, Wei-Zhu, Williams, Marta G., Borin, Marie T., Padbury, Guy E.

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Synthesis and pharmacological evaluation of sulfone substituted HIV protease inhibitors von Schwartz, Theresa M., Bundy, Gordon L., Strohbach, Joseph W., Thaisrivongs, Suvit, Johnson, Paul D., Skulnick, Harvey I., Tomich, Paul K., Lynn, Janet C., Chong, Kong Teck, Hinshaw, Roger R., Raub, Thomas J., Padbury, Guy E., Toth, Lisa N.

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Structure-Based Design of HIV Protease Inhibitors: 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Non-peptidic Inhibitors von Thaisrivongs, Suvit, Tomich, Paul K, Watenpaugh, Keith D, Chong, Kong-Teck, Howe, W. Jeffrey, Yang, Chih-Ping, Strohbach, Joseph W, Turner, Steve R, McGrath, James P

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Fully automated high-performance liquid chromatographic method for the determination of carzelesin (U-80,244) and metabolites (U-76,073 and U-76,074) in human plasma von van Tellingen, Olaf, Pels, Esther M., Henrar, Roland E.C., Schaaf, Lawrence J., Padbury, Guy E., Beijnen, Jos H., Nooijen, Willem J.

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Synthesis of Novel 2,4-Diaminopyrrolo[2,3-d]pyrimidines with Antioxidant, Neuroprotective, and Antiasthma Activity von Bundy, Gordon L, Ayer, Donald E, Banitt, Lee S, Belonga, Kenneth L, Mizsak, Stephen A, Palmer, John R, Tustin, James M, Chin, Jia En, Hall, Edward D

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Cytoxicity and antitumor activity of Carzelesin, a prodrug cyclopropylpyrroloindole analogue von LI, L. H, DEKONING, T. F, GEBHARD, I, KELLY, R. C, KRUEGER, W. C, MCGOVREN, J. P, PADBURY, G. E, PETZOLD, G. L, WALLACE, T. L, OUDING, R. J, PRAIRIE, M. D

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ChemInform Abstract: Synthesis and Pharmacological Evaluation of Sulfone Substituted HIV Protease Inhibitors von SCHWARTZ, T. M., BUNDY, G. L., STROHBACH, J. W., THAISRIVONGS, S., JOHNSON, P. D., SKULNICK, H. I., TOMICH, P. K., LYNN, J. C., CHONG, K. T., HINSHAW, R. R., RAUB, T. J., PADBURY, G. E., TOTH, L. N.

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Expression and localization of Inter-alpha Inhibitors in rodent brain von Chen, X, Rivard, L, Naqvi, S, Nakada, S, Padbury, J.F, Sanchez-Esteban, J, Stopa, E.G, Lim, Y.-P, Stonestreet, B.S

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Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection: A Randomized Controlled Trial von Neoptolemos, John P, Stocken, Deborah D, Bassi, Claudio, Ghaneh, Paula, Cunningham, David, Goldstein, David, Padbury, Robert, Moore, Malcolm J, Gallinger, Steven, Mariette, Christophe, Wente, Moritz N, Izbicki, Jakob R, Friess, Helmut, Lerch, Markus M, Dervenis, Christos, Oláh, Attila, Butturini, Giovanni, Doi, Ryuichiro, Lind, Pehr A, Smith, David, Valle, Juan W, Palmer, Daniel H, Buckels, John A, Thompson, Joyce, McKay, Colin J, Rawcliffe, Charlotte L, Büchler, Markus W, European Study Group for Pancreatic Cancer, for the

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Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model von Moore, Richard G, Lange, Thilo S, Robinson, Katina, Kim, Kyu K, Uzun, Alper, Horan, Timothy C, Kawar, Nada, Yano, Naohiro, Chu, Sharon R, Mao, Quanfu, Brard, Laurent, DePaepe, Monique E, Padbury, James F, Arnold, Leggy A, Brodsky, Alexander, Shen, Tun-Li, Singh, Rakesh K

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Endotoxin-induced lung maturation in preterm lambs is not mediated by cortisol von JOBE, Alan H, NEWNHAM, John P, WILLET, Karen E, MOSS, Timothy J, ERVIN, M. Gore, PADBURY, James F, SLY, Peter, IKEGAMI, Machiko

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Interleukin-1β Transfer across the Blood–Brain Barrier in the Ovine Fetus von Sadowska, Grazyna B, Chen, Xiaodi, Zhang, Jiyong, Lim, Yow-Pin, Cummings, Erin E, Makeyev, Oleksandr, Besio, Walter G, Gaitanis, John, Padbury, James F, Banks, William A, Stonestreet, Barbara S

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Proposed standards for reporting outcomes of treating biliary injuries von Cho, Jai Young, Baron, Todd H., Carr-Locke, David L., Chapman, William C., Costamagna, Guido, de Santibanes, Eduardo, Dominguez Rosado, Ismael, Garden, O. James, Gouma, Dirk, Lillemoe, Keith D., Angel Mercado, Miguel, Mullady, Daniel K., Padbury, Robert, Picus, Daniel, Pitt, Henry A., Sherman, Stuart, Shlansky-Goldberg, Richard, Tornqvist, Bjorn, Strasberg, Steven M.

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The Impact of Primary Hyperparathyroidism on the Oral Cavity von Padbury, Allan D., Tözüm, Tolga F., Taba, Mario, Ealba, Erin L., West, Brady T., Burney, Richard E., Gauger, Paul G., Giannobile, William V., McCauley, Laurie K.

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Antibody targeting of stem cells to infarcted myocardium von Lee, Randall J, Fang, Qizhi, Davol, Pamela A, Gu, Yiping, Sievers, Richard E, Grabert, Ryan C, Gall, Jonathan M, Tsang, Eric, Yee, Michael S, Fok, Hubert, Huang, Ngan F, Padbury, James F, Larrick, James W, Lum, Lawrence G

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