Membrane recycling due to low and high rates of nerve stimulation at release sites in the amphibian (Bufo marinus) neuromuscular junction von Everett, Alan W., Packard, Sarah J., Cosby, Mark, Milne, Robin K.

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Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials von Armitage, Jane, Baigent, Colin, Barnes, Elizabeth, Betteridge, D John, Blackwell, Lisa, Blazing, Michael, Bowman, Louise, Braunwald, Eugene, Byington, Robert, Cannon, Christopher, Clearfield, Michael, Colhoun, Helen, Collins, Rory, Dahlöf, Björn, Davies, Kelly, Davis, Barry, de Lemos, James, Downs, John R, Durrington, Paul, Emberson, Jonathan, Fellström, Bengt, Flather, Marcus, Ford, Ian, Franzosi, Maria Grazia, Fulcher, Jordan, Fuller, John, Furberg, Curt, Gordon, David, Goto, Shinya, Gotto, Antonio, Halls, Heather, Harper, Charlie, Hawkins, C Morton, Herrington, Will, Hitman, Graham, Holdaas, Hallvard, Holland, Lisa, Jardine, Alan, Jukema, J Wouter, Kastelein, John, Kean, Sharon, Keech, Anthony, Kirby, Adrienne, Kjekshus, John, Knatterud (deceased), Genell, Knopp (deceased), Robert, Koenig, Wolfgang, Koren, Michael, Krane, Vera, Landray, Martin J, LaRosa, John, Lonn, Eva, MacFarlane, Peter, MacMahon, Stephen, Maggioni, Aldo, Marchioli, Roberto, Marschner, Ian, Mihaylova, Borislava, Moyé, Lemuel, Murphy, Sabina, Nakamura, Haruo, Neil, Andrew, Newman, Connie, O'Connell, Rachel, Packard, Chris, Parish, Sarah, Pedersen, Terje, Peto, Richard, Pfeffer, Marc, Poulter, Neil, Preiss, David, Reith, Christina, Ridker, Paul, Robertson, Michele, Sacks, Frank, Sattar, Naveed, Schmieder, Roland, Serruys, Patrick, Sever, Peter, Shaw, John, Shear, Charles, Simes, John, Sleight, Peter, Spata, Enti, Tavazzi, Luigi, Tobert, Jonathan, Tognoni, Gianni, Tonkin, Andrew, Trompet, Stella, Varigos, John, Wanner, Christoph, Wedel, Hans, White, Harvey, Wikstrand, John, Wilhelmsen, Lars, Wilson, Kate, Young, Robin, Yusuf, Salim, Zannad, Faiez

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Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase von Ernst, Justin T, Thompson, Peggy A, Nilewski, Christian, Sprengeler, Paul A, Sperry, Samuel, Packard, Garrick, Michels, Theodore, Xiang, Alan, Tran, Chinh, Wegerski, Christopher J, Eam, Boreth, Young, Nathan P, Fish, Sarah, Chen, Joan, Howard, Haleigh, Staunton, Jocelyn, Molter, Jolene, Clarine, Jeff, Nevarez, Andres, Chiang, Gary G, Appleman, Jim R, Webster, Kevin R, Reich, Siegfried H

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Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial von Perkins, Gavin D, Prof, Lall, Ranjit, PhD, Quinn, Tom, Prof, Deakin, Charles D, Prof, Cooke, Matthew W, Prof, Horton, Jessica, MSc, Lamb, Sarah E, Prof, Slowther, Anne-Marie, DPhil, Woollard, Malcolm, Prof, Carson, Andy, FRCGP, Smyth, Mike, MSc, Whitfield, Richard, BSc, Williams, Amanda, MA, Pocock, Helen, MSc, Black, John J M, FCEM, Wright, John, FCEM, Han, Kyee, FCEM, Gates, Simon, Prof

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The characterization of breast anatomical metrics using dedicated breast CT von Huang, Shih-Ying, Boone, John M., Yang, Kai, Packard, Nathan J., McKenney, Sarah E., Prionas, Nicolas D., Lindfors, Karen K., Yaffe, Martin J.

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Dietary Manipulations That Induce Ketosis Activate the HPA Axis in Male Rats and Mice: A Potential Role for Fibroblast Growth Factor-21 von Ryan, Karen K, Packard, Amy E B, Larson, Karlton R, Stout, Jayna, Fourman, Sarah M, Thompson, Abigail M K, Ludwick, Kristen, Habegger, Kirk M, Stemmer, Kerstin, Itoh, Nobuyuki, Perez-Tilve, Diego, Tschöp, Matthias H, Seeley, Randy J, Ulrich-Lai, Yvonne M

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Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease von Zanoni, Paolo, Khetarpal, Sumeet A., Larach, Daniel B., Hancock-Cerutti, William F., Millar, John S., Cuchel, Marina, DerOhannessian, Stephanie, Kontush, Anatol, Surendran, Praveen, Saleheen, Danish, Trompet, Stella, Jukema, J. Wouter, De Craen, Anton, Deloukas, Panos, Sattar, Naveed, Ford, Ian, Packard, Chris, Majumder, Abdullah al Shafi, Alam, Dewan S., Di Angelantonio, Emanuele, Abecasis, Goncalo, Chowdhury, Rajiv, Erdmann, Jeanette, Nordestgaard, Børge G., Nielsen, Sune F., Tybjærg-Hansen, Anne, Schmidt, Ruth Frikke, Kuulasmaa, Kari, Liu, Dajiang J., Perola, Markus, Blankenberg, Stefan, Salomaa, Veikko, Männistö, Satu, Amouyel, Philippe, Arveiler, Dominique, Ferrieres, Jean, Müller-Nurasyid, Martina, Ferrario, Marco, Kee, Frank, Willer, Cristen J., Samani, Nilesh, Schunkert, Heribert, Butterworth, Adam S., Howson, Joanna M. M., Peloso, Gina M., Stitziel, Nathan O., Danesh, John, Kathiresan, Sekar, Rader, Daniel J.

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Targeting Oncogene mRNA Translation in B-Cell Malignancies with eFT226, a Potent and Selective Inhibitor of eIF4A von Thompson, Peggy A, Eam, Boreth, Young, Nathan P, Fish, Sarah, Chen, Joan, Barrera, Maria, Howard, Haleigh, Sung, Eric, Parra, Ana, Staunton, Jocelyn, Chiang, Gary G, Gerson-Gurwitz, Adina, Wegerski, Christopher J, Nevarez, Andres, Clarine, Jeff, Sperry, Samuel, Xiang, Alan, Nilewski, Christian, Packard, Garrick K, Michels, Theodore, Tran, Chinh, Sprengeler, Paul A, Ernst, Justin T, Reich, Siegfried H, Webster, Kevin R

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Potassium carbonate-silica: a highly effective stationary phase for the chromatographic removal of organotin impurities von Harrowven, David C, Curran, Dennis P, Kostiuk, Sarah L, Wallis-Guy, Ian L, Whiting, Sally, Stenning, Kerri J, Tang, Bencan, Packard, Emma, Nanson, Lana

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Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use von Jiang, Yu, Hughey, Jordan M., Zhan, Xiaowei, Gong, Jian, Batini, Chiara, Liu, MengZhen, Surendran, Praveen, Young, Robin, Nielsen, Sune Fallgaard, Kontto, Jukka, Perola, Markus, Caslake, Muriel, Reily, Dermot F., Vogt, Thomas, Sattar, Naveed, Ford, Ian, Alam, Dewan S., Majumder, Abdulla al Shafi, Di Angelantonio, Emanuele, Chowdhury, Rajiv, Arveiler, Dominique, Blankenberg, Stefan, Veronesi, Giovanni, EPIC-CVD Consortium, Frossard, Philippe, Nordestgaard, Børge Grønne, Saleheen, Danish, Danesh, John, Butterworth, Adam S., Warren, Helen R., Tragante, Vinicius, Altmaier, Elisabeth, Luan, Jian’an, Scott, Robert A., Stirrups, Kathleen, Marouli, Eirini, Karpe, Fredrik, Poulter, Neil, Rolandsson, Olov, Chambers, John C., Kooner, Jaspal S., Wareham, Nicholas J., Renström, Frida, Hallmans, Göran, Marioni, Riccardo E., Corley, Janie, Starr, John M., van der Meer, Peter, Yavas, Ersin, Vaartjes, Ilonca, Asselbergs, Folkert W., Grabe, Hans J., Nauck, Matthias, Pharoah, Paul D.P., Dunning, Alison M., Dennis, Joe G., Tyrrell, Jessica, Mihailov, Evelin, Metspalu, Andres, Palmer, Colin N.A., Hall, Ian P., Strachan, David P., Understanding Society Scientific Group, Munroe, Patricia B., Jansson, Jan-Håkan, Franks, Paul W., Deloukas, Panos, Chou, Yi-Ling, Faul, Jessica D., Hammerschlag, Anke R., Hsu, Chris, Lai, Dongbing, Le, Nhung, Loukola, Anu, Mangino, Massimo, Melbourne, Carl A., Pistis, Giorgio, Qaiser, Beenish, Stringham, Heather, Wetherill, Leah, Bierut, Laura, Chen, Chu, Eaton, Charles B., Iacono, William G., Polderman, Tinca J., Schlessinger, David, Scholte, H. Steven, Smith, Jennifer A., Boehnke, Michael, Cucca, Francesco, David, Sean P., Foroud, Tatiana, Kardia, Sharon L.R., Madden, Pamela, McGue, Matt, Posthuma, Danielle, Spector, Timothy, Stram, Daniel, Kaprio, Jaakko, Vrieze, Scott

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Clinical phenotype of the recurrent 1q21.1 copy-number variant von Bernier, Raphael, Steinman, Kyle J., Reilly, Beau, Wallace, Arianne Stevens, Sherr, Elliott H., Pojman, Nicholas, Mefford, Heather C., Gerdts, Jennifer, Earl, Rachel, Hanson, Ellen, Goin-Kochel, Robin P., Berry, Leandra, Kanne, Stephen, Snyder, LeeAnne Green, Spence, Sarah, Ramocki, Melissa B., Evans, David W., Spiro, John E., Martin, Christa L., Ledbetter, David H., Chung, Wendy K.

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Simons Variation in Individuals Project (Simons VIP): A Genetics-First Approach to Studying Autism Spectrum and Related Neurodevelopmental Disorders von The Simons VIP Consortium

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Strategic Diastereoselective C1 Functionalization in the Aza-Rocaglamide Scaffold toward Natural Product-Inspired eIF4A Inhibitors von Nilewski, Christian, Michels, Theodore D, Xiang, Alan X, Packard, Garrick K, Sprengeler, Paul A, Eam, Boreth, Fish, Sarah, Thompson, Peggy A, Wegerski, Christopher J, Ernst, Justin T, Reich, Siegfried H

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Lipoprotein-associated phospholipase A2 and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

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1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties von Nilewski, Christian, Michels, Theodore D., Packard, Garrick K., Xiang, Alan X., Sprengeler, Paul A., Eam, Boreth, Fish, Sarah, Thompson, Peggy A., Wegerski, Christopher J., Nevarez, Andres, Clarine, Jeff, Sperry, Samuel, Ernst, Justin T., Reich, Siegfried H.

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Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies von Thompson, Alexander, Gao, Pei, Orfei, Lia, Watson, Sarah, Di Angelantonio, Emanuele, Kaptoge, Stephen, Ballantyne, Christie, Cannon, Christopher P, Criqui, Michael, Cushman, Mary, Hofman, Albert, Packard, Chris, Thompson, Simon G, Collins, Rory, Danesh, John

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Guideline concordance of aspirin use for primary prevention in adult outpatients von Chipalkatti, Naina, Barnes, Geoffrey D., Bashaw, Linda, Davie, Adam, Griggs, Jennifer J., Harrod, Molly, Kurlander, Jacob E., Medaugh, Christine, Packard, Rebeca, Powell, Corey, Sood, Suman, Spranger, Elizabeth, Vordenberg, Sarah E., Schaefer, Jordan K.

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Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals von Ntalla, Ioanna, Karthikeyan, Savita, Mifsud, Borbala, Kraja, Aldi T., Cartwright, James H., Hellwege, Jacklyn N., Giri, Ayush, Tragante, Vinicius, Prins, Bram P., Cabrera, Claudia P., Eales, James M., Akbarov, Artur, Bielak, Lawrence F., Brody, Jennifer A., Drenos, Fotios, Nielsen, Sune Fallgaard, Faul, Jessica D., Franceschini, Nora, Gao, He, Giulianini, Franco, Hwang, Shih-Jen, Kanoni, Stavroula, Lindström, Jaana, Luan, Jian’an, Mahajan, Anubha, Malerba, Giovanni, Perola, Markus, Richard, Melissa, Richardson, Tom G., Sepúlveda, Nuno, Thériault, Sébastien, Trompet, Stella, Varga, Tibor V., Velez Edwards, Digna R., Veronesi, Giovanni, Weiss, Stefan, Willems, Sara M., Young, Robin, Zhang, Weihua, Zhao, Wei, Evangelou, Evangelos, Aeschbacher, Stefanie, Asllanaj, Eralda, Mutsert, Renée de, Dörr, Marcus, Gaziano, J. Michael, Have, Christian T., Kajantie, Eero, Kamat, Mihir, Karpe, Fredrik, Moitry, Marie, Peters, James, Rossouw, Jacques, Sever, Peter S., Sigurdsson, Emil L., Skaaby, Tea, Sun, Yan V., Trabetti, Elisabetta, Vaartjes, Ilonca, Buring, Julie E., Chowdhury, Rajiv, Correa, Adolfo, Deary, Ian J., Deloukas, Panos, Ferrières, Jean, Fornage, Myriam, Gaunt, Tom R., Harris, Tamara B., Järvelin, Marjo-Riitta, Kooperberg, Charles, Launer, Lenore J., Lind, Lars, Majumder, Abdulla al Shafi, Laakso, Markku, Melander, Olle, Mohlke, Karen L., Orho-Melander, Marju, Palmas, Walter, Polasek, Ozren, Province, Michael A., Rolandsson, Olov, Rosendaal, Frits R., Rotter, Jerome I., Samani, Nilesh J., Soranzo, Nicole, Spector, Timothy D., Starr, John M., van der Harst, Pim, van der Meer, Peter, Verweij, Niek, Virtamo, Jarmo, Wareham, Nicholas J., Langenberg, Claudia, Liu, Chunyu, Manning, Alisa K., Morrison, Alanna C., O’Donnell, Christopher J., Saleheen, Danish, Boerwinkle, Eric, Chasman, Daniel I.

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Abstract 2698: eFT226, a potent and selective inhibitor of eIF4A, is efficacious in preclinical models of lymphoma von Thompson, Peggy A., Eam, Boreth, Young, Nathan P., Fish, Sarah, Chen, Joan, Barrera, Maria, Howard, Haleigh, Sung, Eric, Parra, Ana, Staunton, Jocelyn, Chiang, Gary G., Wegerski, Christopher J., Nevarez, Andres, Clarine, Jeff, Sperry, Samuel, Xiang, Alan, Tran, Chinh, Nilewski, Christian, Packard, Garrick K., Michels, Theodore, Sprengeler, Paul A., Ernst, Justin T., Reich, Siegfried H., Webster, Kevin R.

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Preclinical Evaluation of eFT226, a Novel, Potent and Selective eIF4A Inhibitor with Anti-Tumor Activity in B-Cell Malignancies von Thompson, Peggy A, Eam, Boreth, Young, Nathan P, Fish, Sarah, Chen, Joan, Barrera, Maria, Howard, Haleigh, Parra, Ana, Molter, Jolene, Staunton, Jocelyn, Hung, Ivy NJ, Parker, Greg S, Chiang, Gary G, Wegerski, Chris J, Nevarez, Andres, Clarine, Jeff, Sperry, Sam, Xiang, Alan, Tran, Chinh, Nilewski, Christian, Packard, Garrick K, Michels, Theodore, Sprengeler, Paul A, Ernst, Justin T, Reich, Siegfried H, Webster, Kevin R

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