GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production von Miller, Corin, Pachanski, Michele J, Kirkland, Melissa E, Kosinski, Daniel T, Mane, Joel, Bunzel, Michelle, Cao, Jin, Souza, Sarah, Thomas-Fowlkes, Brande, Di Salvo, Jerry, Weinglass, Adam B, Li, Xiaoyan, Myers, Robert W, Knagge, Kevin, Carrington, Paul E, Hagmann, William K, Trujillo, Maria E

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GPR40 reduces food intake and body weight through GLP-1 von Gorski, Judith N, Pachanski, Michele J, Mane, Joel, Plummer, Christopher W, Souza, Sarah, Thomas-Fowlkes, Brande S, Ogawa, Aimie M, Weinglass, Adam B, Di Salvo, Jerry, Cheewatrakoolpong, Boonlert, Howard, Andrew D, Colletti, Steven L, Trujillo, Maria E

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GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent von Pachanski, Michele J, Kirkland, Melissa E, Kosinski, Daniel T, Mane, Joel, Cheewatrakoolpong, Boonlert, Xue, Jiyan, Szeto, Daphne, Forrest, Gail, Miller, Corin, Bunzel, Michelle, Plummer, Christopher W, Chobanian, Harry R, Miller, Michael W, Souza, Sarah, Thomas-Fowlkes, Brande S, Ogawa, Aimie M, Weinglass, Adam B, Di Salvo, Jerry, Li, Xiaoyan, Feng, Yue, Tatosian, Daniel A, Howard, Andrew D, Colletti, Steven L, Trujillo, Maria E

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Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus von Xu, Jiayi, Lin, Songnian, Myers, Robert W., Addona, George, Berger, Joel P., Campbell, Brian, Chen, Hsuan-shen, Chen, Zhesheng, Eiermann, George J., Elowe, Nadine H., Farrer, Brian T., Feng, Wen, Fu, Qinghong, Kats-Kagan, Roman, Kavana, Michael, Malkani, Sunita, McMasters, Daniel R., Mitra, Kaushik, Pachanski, Michele J., Tong, Xinchun, Trujillo, Maria E., Xu, Libo, Zhang, Bei, Zhang, Fengqi, Zhang, Rui, Parmee, Emma R.

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Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus von Xu, Jiayi, Lin, Songnian, Myers, Robert W., Trujillo, Maria E., Pachanski, Michele J., Malkani, Sunita, Chen, Hsuan-shen, Chen, Zhesheng, Campbell, Brian, Eiermann, George J., Elowe, Nadine, Farrer, Brian T., Feng, Wen, Fu, Qinghong, Kats-Kagan, Roman, Kavana, Michael, McMasters, Daniel R., Mitra, Kaushik, Tong, Xinchun, Xu, Libo, Zhang, Fengqi, Zhang, Rui, Addona, George H., Berger, Joel P., Zhang, Bei, Parmee, Emma R.

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GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production von Miller, Corin, Pachanski, Michele J, Kirkland, Melissa E, Kosinski, Daniel T, Mane, Joel, Bunzel, Michelle, Cao, Jin, Souza, Sarah, Thomas-Fowlkes, Brande, Di Salvo, Jerry, Weinglass, Adam B, Li, Xiaoyan, Myers, Robert W, Knagge, Kevin, Carrington, Paul E, Hagmann, William K, Trujillo, Maria E

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Structure–Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs von Chen, Helen Y., Plummer, Christopher W., Xiao, Dong, Chobanian, Harry R., DeMong, Duane, Miller, Michael, Trujillo, Maria E., Kirkland, Melissa, Kosinski, Daniel, Mane, Joel, Pachanski, Michele, Cheewatrakoolpong, Boonlert, Di Salvo, Jerry, Thomas-Fowlkes, Brande, Souza, Sarah, Tatosian, Daniel A., Chen, Qing, Hafey, Michael J., Houle, Robert, Nolting, Andrew F., Orr, Robert, Ehrhart, Juliann, Weinglass, Adam B., Tschirret-Guth, Richard, Howard, Andrew D., Colletti, Steven L.

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Design, synthesis and biological evaluation of indane derived GPR40 agoPAMs von Pio, Barbara, Chobanian, Harry R., Guo, Yan, Josien, Hubert, Hagmann, William K., Miller, Michael, Trujillo, Maria E., Kirkland, Melissa, Kosinski, Daniel, Mane, Joel, Pachanski, Michele, Cheewatrakoolpong, Boonlert, Ashley, Eric, Orr, Robert, Wright, Michael J., Bugianesi, Randal, Souza, Sarah, Zhang, Xiaoping, Di Salvo, Jerry, Weinglass, Adam B., Tschirret-Guth, Richard, Samuel, Koppara, Chen, Qing, Shang, Jackie, Lamca, James, Ehrhart, Juliann, Nargund, Ravi, Howard, Andrew D., Colletti, Steven L.

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Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects von Lombardo, Matthew, Bender, Kate, London, Clare, Plotkin, Michael A., Kirkland, Melissa, Mane, Joel, Pachanski, Michele, Geissler, Wayne, Cummings, John, Habulihaz, Bahanu, Akiyama, Taro E., Di Salvo, Jerry, Madeira, Maria, Pols, Joanna, Powles, Mary Ann, Finley, Michael F., Johnson, Eric, Roussel, Thomas, Uebele, Victor N., Crespo, Alejandro, Leung, Dennis, Alleyne, Candice, Trusca, Dorina, Lei, Ying, Howard, Andrew D., Ujjainwalla, Feroze, Tata, James R., Sinz, Christopher J.

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Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes von Shah, Shrenik K, He, Shuwen, Guo, Liangqin, Truong, Quang, Qi, Hongbo, Du, Wu, Lai, Zhong, Liu, Jian, Jian, Tianying, Hong, Qingmei, Dobbelaar, Peter, Ye, Zhixiong, Sherer, Edward, Feng, Zhe, Yu, Yang, Wong, Frederick, Samuel, Koppara, Madiera, Maria, Karanam, Bindhu V, Reddy, Vijay B, Mitelman, Stan, Tong, Sharon X, Chicchi, Gary G, Tsao, Kwei-Lan, Trusca, Dorina, Feng, Yue, Wu, Margaret, Shao, Qing, Trujillo, Maria E, Eiermann, George J, Li, Cai, Pachanski, Michele, Fernandez, Guillermo, Nelson, Donald, Bunting, Patricia, Morissette, Pierre, Volksdorf, Sylvia, Kerr, Janet, Zhang, Bei B, Howard, Andrew D, Zhou, Yun-Ping, Pasternak, Alexander, Nargund, Ravi P, Hagmann, William K

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Design and Synthesis of Novel, Selective GPR40 AgoPAMs von Plummer, Christopher W., Clements, Matthew J., Chen, Helen, Rajagopalan, Murali, Josien, Hubert, Hagmann, William K., Miller, Michael, Trujillo, Maria E., Kirkland, Melissa, Kosinski, Daniel, Mane, Joel, Pachanski, Michele, Cheewatrakoolpong, Boonlert, Nolting, Andrew F., Orr, Robert, Christensen, Melodie, Campeau, Louis-Charles, Wright, Michael J., Bugianesi, Randal, Souza, Sarah, Zhang, Xiaoping, Di Salvo, Jerry, Weinglass, Adam B., Tschirret-Guth, Richard, Nargund, Ravi, Howard, Andrew D., Colletti, Steven L.

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Design, Synthesis, and Evaluation of Novel and Selective G‑protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists von Cox, Jason M, Chu, Hong D, Chelliah, Mariappan V, Debenham, John S, Eagen, Keith, Lan, Ping, Lombardo, Matthew, London, Clare, Plotkin, Michael A, Shah, Unmesh, Sun, Zhongxiang, Vaccaro, Henry M, Venkatraman, Srikanth, Suzuki, Takao, Wang, Nengxue, Ashley, Eric R, Crespo, Alejandro, Madeira, Maria, Leung, Dennis H, Alleyne, Candice, Ogawa, Aimie M, Souza, Sarah, Thomas-Fowlkes, Brande, Di Salvo, Jerry, Weinglass, Adam, Kirkland, Melissa, Pachanski, Michele, Powles, Mary Ann, Tozzo, Effie, Akiyama, Taro E, Ujjainwalla, Feroze, Tata, James R, Sinz, Christopher J

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Corrigendum to “Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects” [Bioorg. Med. Chem. Lett. 26 (2016) 5724–5728]... von Lombardo, Matthew, Bender, Kate, London, Clare, Plotkin, Michael A., Kirkland, Melissa, Mane, Joel, Pachanski, Michele, Geissler, Wayne, Cummings, John, Habulihaz, Bahanu, Akiyama, Taro E., Di Salvo, Jerry, Madeira, Maria, Pols, Joanna, Powles, Mary Ann, Finley, Michael F., Johnson, Eric, Roussel, Thomas, Uebele, Victor N., Crespo, Alejandro, Leung, Dennis, Alleyne, Candice, Trusca, Dorina, Lei, Ying, Howard, Andrew D., Ujjainwalla, Feroze, Tata, James R., Sinz, Christopher J.

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Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes von Guo, Liangqin, Parker, Dann L, Zang, Yi, Sweis, Ramzi F, Liu, Weiguo, Sherer, Edward C, Buist, Nicole, Terebetski, Jenna, Kelly, Terri, Bugianesi, Randal, Priest, Birgit T, Dingley, Karen H, Li, Xiaofang, Mitelman, Stan, Salituro, Gino, Trujillo, Maria E, Pachanski, Michele, Kirkland, Melissa, Powles, Mary Ann, Eiermann, George J, Feng, Yue, Shang, Jin, Howard, Andrew D, Ujjainwalla, Feroze, Sinz, Christopher J, Debenham, John S, Edmondson, Scott D, Nargund, Ravi P, Hagmann, William K, Li, Derun

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Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists von Li, Derun, Wu, Zhicai, Yu, Yang, Ball, Richard G, Guo, Liangqin, Sherer, Edward, He, Shuwen, Hong, Qingmei, Lai, Zhong, Qi, Hongbo, Truong, Quang, Yang, David X, Chicchi, Gary G, Tsao, Kwei-Lan, Trusca, Dorina, Trujillo, Maria, Pachanski, Michele, Eiermann, George J, Howard, Andrew D, Zhou, Yun-Ping, Zhang, Bei B, Nargund, Ravi P, Hagmann, William K

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