High-dose atorvastatin causes a rapid sustained increase in human serum PCSK9 and disrupts its correlation with LDL cholesterol von Welder, Greg, Zineh, Issam, Pacanowski, Michael A., Troutt, Jason S., Cao, Guoqing, Konrad, Robert J.

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Pharmacogenomics in the Assessment of Therapeutic Risks versus Benefits: Inside the United States Food and Drug Administration von Zineh, Issam, Pacanowski, Michael A.

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Clinical Trial Designs to Support Clinical Utility of Pharmacogenomic Testing von Drozda, Katarzyna, Pacanowski, Michael A.

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The US Food and Drug Administration's Model‐Informed Drug Development Paired Meeting Pilot Program: Early Experience and Impact von Madabushi, Rajanikanth, Benjamin, Jessica M., Grewal, Renmeet, Pacanowski, Michael A., Strauss, David G., Wang, Yaning, Zhu, Hao, Zineh, Issam

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New Evidence about an Old Drug — Risk with Codeine after Adenotonsillectomy von Racoosin, Judith A, Roberson, David W, Pacanowski, Michael A, Nielsen, David R

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Pharmacogenetic Labeling of FDA-Approved Drugs: A Regulatory Retrospective von Drozda, Katarzyna, Pacanowski, Michael A, Grimstein, Christian, Zineh, Issam

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The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response von Lewis, Joshua P, Horenstein, Richard B, Ryan, Kathleen, O’Connell, Jeffrey R, Gibson, Quince, Mitchell, Braxton D, Tanner, Keith, Chai, Sumbul, Bliden, Kevin P, Tantry, Udaya S, Peer, Cody J, Figg, William D, Spencer, Shawn D, Pacanowski, Michael A, Gurbel, Paul A, Shuldiner, Alan R

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Dosing recommendations for pharmacogenetic interactions related to drug metabolism von Filipski, Kelly K, Pacanowski, Michael A, Ramamoorthy, Anuradha, Feero, William Gregory, Freedman, Andrew N

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Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation von Pacanowski, Michael A, Zineh, Issam, Li, Haihong, Johnson, B Delia, Cooper-DeHoff, Rhonda M, Bittner, Vera, McNamara, Dennis M, Sharaf, Barry L, Merz, C Noel Bairey, Pepine, Carl J, Johnson, Julie A

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Effectiveness of clopidogrel dose escalation to normalize active metabolite exposure and antiplatelet effects in CYP2C19 poor metabolizers von Horenstein, Richard B., Madabushi, Rajnikanth, Zineh, Issam, Yerges-Armstrong, Laura M., Peer, Cody J., Schuck, Robert N., Figg, William Douglas, Shuldiner, Alan R., Pacanowski, Michael A.

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Cardiovascular therapies and associated glucose homeostasis: implications across the dysglycemia continuum von Cooper-DeHoff, Rhonda M, Pacanowski, Michael A, Pepine, Carl J

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Acute pain pathways: protocol for a prospective cohort study von Jeffery, Molly Moore, Ahadpour, Mitra, Allen, Summer, Araojo, Richardae, Bellolio, Fernanda, Chang, Nancy, Ciaccio, Laura, Emanuel, Lindsay, Fillmore, Jonathan, Gilbert, Gregg H, Koussis, Patricia, Lee, Christine, Lipkind, Heather, Mallama, Celeste, Meyer, Tamra, Moncur, Megan, Nuckols, Teryl, Pacanowski, Michael A, Page, David B, Papadopoulos, Elektra, Ritchie, Jessica D, Ross, Joseph S, Shah, Nilay D, Soukup, Mat, St. Clair, Christopher O, Tamang, Stephen, Torbati, Sam, Wallace, Douglas W, Zhao, Yueqin, Heckmann, Rebekah

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Identification of Stevens–Johnson syndrome and toxic epidermal necrolysis in electronic health record databases von Davis, Robert L., Gallagher, Mia A., Asgari, Maryam M., Eide, Melody J., Margolis, David J., Macy, Eric, Burmester, James K., Selvam, Nandini, Boscarino, Joseph A., Cromwell, Lee F., Feigelson, Heather S., Kuntz, Jennifer L., Pawloski, Pamala A., Penfold, Robert B., Raebel, Marsha A., Sridhar, Gayathri, Wu, Ann, La Grenade, Lois A., Pacanowski, Michael A., Pinheiro, Simone P.

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A sensitive and rapid ultra HPLC–MS/MS method for the simultaneous detection of clopidogrel and its derivatized active thiol metabolite in human plasma von Peer, Cody J., Spencer, Shawn D., VanDenBerg, Dustin A.H., Pacanowski, Michael A., Horenstein, Richard B., Figg, William D.

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Effect of Cytochrome P450 3A5 Genotype on Atorvastatin Pharmacokinetics and Its Interaction with Clarithromycin von Shin, Jaekyu, Pauly, Daniel F., Pacanowski, Michael A., Langaee, Taimour, Frye, Reginald F., Johnson, Julie A.

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Plasma coenzyme Q10 predicts lipid-lowering response to high-dose atorvastatin von Pacanowski, Michael A., PharmD, MPH, Frye, Reginald F., PharmD, PhD, Enogieru, Osatohanmen, Schofield, Richard S., MD, Zineh, Issam, PharmD

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Impact of TCF7L2 single nucleotide polymorphisms on hydrochlorothiazide-induced diabetes von Karnes, Jason H, Gong, Yan, Pacanowski, Michael A, McDonough, Caitrin W, Arwood, Meghan J, Langaee, Taimour Y, Pepine, Carl J, Johnson, Julie A, Cooper-DeHoff, Rhonda M

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Pharmacogenetic Labeling of FDA-Approved Drugs von Drozda, Katarzyna, PharmD, MS, Pacanowski, Michael A., PharmD, MPH, Grimstein, Christian, PhD, Zineh, Issam, PharmD, MPH

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Liver X receptor α gene polymorphisms and variable cardiovascular outcomes in patients treated with antihypertensive therapy: results from the INVEST-GENES study von Price, Elvin Tyrone, Pacanowski, Michael A, Martin, Michael A, Cooper-DeHoff, Rhonda M, Pepine, Carl J, Zineh, Issam, Johnson, Julie A

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Interindividual variability in oral antidiabetic drug disposition and response: the role of drug transporter polymorphisms von Pacanowski, Michael A, Hopley, Charles W, Aquilante, Christina L

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