Synthesis and Pharmacology of (Pyridin-2-yl)methanol Derivatives as Novel and Selective Transient Receptor Potential Vanilloid 3 Antagonists von Gomtsyan, Arthur, Schmidt, Robert G, Bayburt, Erol K, Gfesser, Gregory A, Voight, Eric A, Daanen, Jerome F, Schmidt, Diana L, Cowart, Marlon D, Liu, Huaqing, Altenbach, Robert J, Kort, Michael E, Clapham, Bruce, Cox, Phil B, Shrestha, Anurupa, Henry, Rodger, Whittern, David N, Reilly, Regina M, Puttfarcken, Pamela S, Brederson, Jill-Desiree, Song, Ping, Li, Bin, Huang, Susan M, McDonald, Heath A, Neelands, Torben R, McGaraughty, Steve P, Gauvin, Donna M, Joshi, Shailen K, Banfor, Patricia N, Segreti, Jason A, Shebley, Mohamad, Faltynek, Connie R, Dart, Michael J, Kym, Philip R

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High content screen microscopy analysis of Aβ1–42 -induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholi... von Hu, Min, Schurdak, Mark E, Puttfarcken, Pamela S, El Kouhen, Rachid, Gopalakrishnan, Murali, Li, Jinhe

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TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low pH in HEK293 cells von Vos, Melissa H., Neelands, Torben R., McDonald, Heath A., Choi, Won, Kroeger, Paul E., Puttfarcken, Pamela S., Faltynek, Connie R., Moreland, Robert B., Han, Ping

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Different nicotinic acetylcholine receptor subtypes mediating striatal and prefrontal cortical [ 3H]dopamine release von Cao, Ying-Jun, Surowy, Carol S., Puttfarcken, Pamela S.

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Characterization of A-425619 at native TRPV1 receptors: A comparison between dorsal root ganglia and trigeminal ganglia von McDonald, Heath A., Neelands, Torben R., Kort, Michael, Han, Ping, Vos, Melissa H., Faltynek, Connie R., Moreland, Robert B., Puttfarcken, Pamela S.

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Pharmacology of modality-specific transient receptor potential vanilloid-1 antagonists that do not alter body temperature von Reilly, Regina M, McDonald, Heath A, Puttfarcken, Pamela S, Joshi, Shailen K, Lewis, LaGeisha, Pai, Madhavi, Franklin, Pamela H, Segreti, Jason A, Neelands, Torben R, Han, Ping, Chen, Jun, Mantyh, Patrick W, Ghilardi, Joseph R, Turner, Teresa M, Voight, Eric A, Daanen, Jerome F, Schmidt, Robert G, Gomtsyan, Arthur, Kort, Michael E, Faltynek, Connie R, Kym, Philip R

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Discovery of (R)‑1-(7-Chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): A Temperature-Neutral Transient Receptor Potential Vanilloid‑1 (TRPV1)... von Voight, Eric A, Gomtsyan, Arthur R, Daanen, Jerome F, Perner, Richard J, Schmidt, Robert G, Bayburt, Erol K, DiDomenico, Stanley, McDonald, Heath A, Puttfarcken, Pamela S, Chen, Jun, Neelands, Torben R, Bianchi, Bruce R, Han, Ping, Reilly, Regina M, Franklin, Pamela H, Segreti, Jason A, Nelson, Richard A, Su, Zhi, King, Andrew J, Polakowski, James S, Baker, Scott J, Gauvin, Donna M, Lewis, LaGeisha R, Mikusa, Joseph P, Joshi, Shailen K, Faltynek, Connie R, Kym, Philip R, Kort, Michael E

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A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of... von Puttfarcken, Pamela S., Han, Ping, Joshi, Shailen K., Neelands, Torben R., Gauvin, Donna M., Baker, Scott J., Lewis, La Geisha R., Bianchi, Bruce R., Mikusa, Joseph P., Koenig, John R., Perner, Richard J., Kort, Michael E., Honore, Prisca, Faltynek, Connie R., Kym, Philip R., Reilly, Regina M.

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Discovery of TRPV1 antagonist ABT-116 von Brown, Brian S, Keddy, Ryan, Perner, Richard J, DiDomenico, Stanley, Koenig, John R, Jinkerson, Tammie K, Hannick, Steven M, McDonald, Heath A, Bianchi, Bruce R, Honore, Prisca, Puttfarcken, Pamela S, Moreland, Robert B, Marsh, Kennan C, Faltynek, Connie R, Lee, Chih-Hung

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Assessment of nicotinic acetylcholine receptor-mediated release of [ 3H]-norepinephrine from rat brain slices using a new 96-well format assay von Anderson, David J., Puttfarcken, Pamela S., Jacobs, Iris, Faltynek, Connie

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Characterization of nicotinic acetylcholine receptor-mediated [ 3H]-dopamine release from rat cortex and striatum von Puttfarcken, Pamela S, Jacobs, Iris, R. Faltynek, Connie

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In Vitro Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107 von Malysz, John, Anderson, David J., Grønlien, Jens H., Ji, Jianguo, Bunnelle, William H., Håkerud, Monika, Thorin-Hagene, Kirten, Ween, Hilde, Helfrich, Rosalind, Hu, Min, Gubbins, Earl, Gopalakrishnan, Sujatha, Puttfarcken, Pamela S., Briggs, Clark A., Li, Jinhe, Meyer, Michael D., Dyhring, Tino, Ahring, Philip K., Nielsen, Elsebet Ø., Peters, Dan, Timmermann, Daniel B., Gopalakrishnan, Murali

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High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic ac... von Hu, Min, Schurdak, Mark E, Puttfarcken, Pamela S, El Kouhen, Rachid, Gopalakrishnan, Murali, Li, Jinhe

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High content screen microscopy analysis of Aβ 1–42-induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholi... von Hu, Min, Schurdak, Mark E., Puttfarcken, Pamela S., El Kouhen, Rachid, Gopalakrishnan, Murali, Li, Jinhe

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TPRV1b overexpression negatively regulates TPRV1 responsiveness to capsaicin, heat and low pH in HEK293 cells von VOS, Melissa H, NEELANDS, Torben R, MCDONALD, Heath A, CHOI, Won, KROEGER, Paul E, PUTTFARCKEN, Pamela S, FALTYNEK, Connie R, MORELAND, Robert B, PING HAN

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Evidence for Nicotinic Receptors Potentially Modulating Nociceptive Transmission at the Level of the Primary Sensory Neuron: Studies with F11 Cells von Puttfarcken, Pamela S., Manelli, Arlene M., Arneric, Stephen P., Donnelly‐Roberts, Diana L.

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β-Amyloid-induced toxicity in rat hippocampal cells: In vitro evidence for the involvement of free radicals von Manelli, Arlene M., Puttfarcken, Pamela S.

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In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107 von Malysz, John, Anderson, David J, Grønlien, Jens H, Ji, Jianguo, Bunnelle, William H, Håkerud, Monika, Thorin-Hagene, Kirten, Ween, Hilde, Helfrich, Rosalind, Hu, Min, Gubbins, Earl, Gopalakrishnan, Sujatha, Puttfarcken, Pamela S, Briggs, Clark A, Li, Jinhe, Meyer, Michael D, Dyhring, Tino, Ahring, Philip K, Nielsen, Elsebet Ø, Peters, Dan, Timmermann, Daniel B, Gopalakrishnan, Murali

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β-Amyloid peptides initiate the complement cascade without producing a comparable effect on the terminal pathway in vitro von CADMAN, E. D, PUTTFARCKEN, P. S

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Inhibition of Age-Induced β-Amyloid Neurotoxicity in Rat Hippocampal Cells von Puttfarcken, Pamela S., Manelli, Arlene M., Neilly, Joseph, Frail, Donald E.

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