Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069 von Orsi, Douglas L., Pook, Elisabeth, Bräuer, Nico, Friberg, Anders, Lienau, Philip, Lemke, Christopher T., Stellfeld, Timo, Brüggemeier, Ulf, Pütter, Vera, Meyer, Hanna, Baco, Maria, Tang, Stephanie, Cherniack, Andrew D., Westlake, Lindsay, Bender, Samantha A., Kocak, Mustafa, Strathdee, Craig A., Meyerson, Matthew, Eis, Knut, Goldstein, Jonathan T.

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Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo von Siemeister, Gerhard, Mengel, Anne, Fernández-Montalván, Amaury E, Bone, Wilhelm, Schröder, Jens, Zitzmann-Kolbe, Sabine, Briem, Hans, Prechtl, Stefan, Holton, Simon J, Mönning, Ursula, von Ahsen, Oliver, Johanssen, Sandra, Cleve, Arwed, Pütter, Vera, Hitchcock, Marion, von Nussbaum, Franz, Brands, Michael, Ziegelbauer, Karl, Mumberg, Dominik

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Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A von Wortmann, Lars, Bräuer, Nico, Holton, Simon J, Irlbacher, Horst, Weiske, Jörg, Lechner, Christian, Meier, Robin, Karén, Jakob, Siöberg, Catrine Berthold, Pütter, Vera, Christ, Clara D, ter Laak, Antonius, Lienau, Philip, Lesche, Ralf, Nicke, Barbara, Cheung, Shing-Hu, Bauser, Marcus, Haegebarth, Andrea, von Nussbaum, Franz, Mumberg, Dominik, Lemos, Clara

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The Solution Structure of the N-Terminal Domain of E3L Shows a Tyrosine Conformation That May Explain Its Reduced Affinity to Z-DNA in vitro von Kahmann, Jan D., Wecking, Diana A., Putter, Vera, Lowenhaupt, Ky, Kim, Yang-Gyun, Schmieder, Peter, Oschkinat, Hartmut, Rich, Alexander, Schade, Markus

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Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains von Bouché, Léa, Christ, Clara D, Siegel, Stephan, Fernández-Montalván, Amaury E, Holton, Simon J, Fedorov, Oleg, ter Laak, Antonius, Sugawara, Tatsuo, Stöckigt, Detlef, Tallant, Cynthia, Bennett, James, Monteiro, Octovia, Díaz-Sáez, Laura, Siejka, Paulina, Meier, Julia, Pütter, Vera, Weiske, Jörg, Müller, Susanne, Huber, Kilian V. M, Hartung, Ingo V, Haendler, Bernard

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Correction to “Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069” von Orsi, Douglas L., Pook, Elisabeth, Bräuer, Nico, Friberg, Anders, Lienau, Philip, Lemke, Christopher T., Stellfeld, Timo, Brüggemeier, Ulf, Pütter, Vera, Meyer, Hanna, Baco, Maria, Tang, Stephanie, Cherniack, Andrew D., Westlake, Lindsay, Bender, Samantha A., Kocak, Mustafa, Strathdee, Craig A., Meyerson, Matthew, Eis, Knut, Goldstein, Jonathan T.

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Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis von Sugawara, Tatsuo, Nevedomskaya, Ekaterina, Heller, Simon, Böhme, Annika, Lesche, Ralf, Ahsen, Oliver, Grünewald, Sylvia, Nguyen, Holly M., Corey, Eva, Baumgart, Simon J., Georgi, Victoria, Pütter, Vera, Fernández‐Montalván, Amaury, Vasta, James D., Robers, Matthew B., Politz, Oliver, Mumberg, Dominik, Haendler, Bernard

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Expression and Characterization of Relaxin Family Peptide Receptor 1 Variants von Speck, David, Kleinau, Gunnar, Meininghaus, Mark, Erbe, Antje, Einfeldt, Alexandra, Szczepek, Michal, Scheerer, Patrick, Pütter, Vera

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Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A von Friberg, Anders, Rehwinkel, Hartmut, Nguyen, Duy, Pütter, Vera, Quanz, Maria, Weiske, Jörg, Eberspächer, Uwe, Heisler, Iring, Langer, Gernot

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Discovery of novel MDR-Mycobacterium tuberculosis inhibitor by new FRIGATE computational screen von Scheich, Christoph, Szabadka, Zoltán, Vértessy, Beáta, Pütter, Vera, Grolmusz, Vince, Schade, Markus

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Interaction and Assembly of Murine Pre-replicative Complex Proteins in Yeast and Mouse Cells von Kneissl, Margot, Pütter, Vera, Szalay, Aladar A, Grummt, Friedrich

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Transcription termination factor TTF-I exhibits contrahelicase activity during DNA replication von Pütter, Vera, Grummt, Friedrich

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Surface-mutagenesis strategies to enable structural biology crystallization platforms von Schaefer, Martina, Pütter, Vera, Hilpmann, André, Egner, Ursula, Holton, Simon James, Hillig, Roman Christian

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The RESOLUTE consortium: unlocking SLC transporters for drug discovery von Superti-Furga, Giulio, Lackner, Daniel, Wiedmer, Tabea, Ingles-Prieto, Alvaro, Barbosa, Barbara, Girardi, Enrico, Goldmann, Ulrich, Gürtl, Bettina, Klavins, Kristaps, Klimek, Christoph, Lindinger, Sabrina, Liñeiro-Retes, Eva, Müller, André C., Onstein, Svenja, Redinger, Gregor, Reil, Daniela, Sedlyarov, Vitaly, Wolf, Gernot, Crawford, Matthew, Everley, Robert, Hepworth, David, Noell, Stephen, Piotrowski, Mary, Stanton, Robert, Zhang, Hui, Corallino, Salvatore, Faedo, Andrea, Insidioso, Maria, Maresca, Giovanna, Redaelli, Loredana, Sassone, Francesca, Scarabottolo, Lia, Stucchi, Michela, Tarroni, Paola, Tremolada, Sara, Batoulis, Helena, Becker, Andreas, Bender, Eckhard, Chang, Yung-Ning, Ehrmann, Alexander, Müller-Fahrnow, Anke, Pütter, Vera, Zindel, Diana, Hamilton, Bradford, Lenter, Martin, Santacruz, Diana, Viollet, Coralie, Whitehurst, Charles, Johnsson, Kai, Leippe, Philipp, Baumgarten, Birgit, Chang, Lena, Ibig, Yvonne, Pfeifer, Martin, Reinhardt, Jürgen, Schönbett, Julian, Selzer, Paul, Seuwen, Klaus, Bettembourg, Charles, Biton, Bruno, Czech, Jörg, de Foucauld, Hélène, Didier, Michel, Licher, Thomas, Mikol, Vincent, Pommereau, Antje, Puech, Frédéric, Yaligara, Veeranagouda, Edwards, Aled, Bongers, Brandon J., Heitman, Laura H., IJzerman, Ad P., Sijben, Huub J., van Westen, Gerard J.P., Grixti, Justine, Kell, Douglas B., Mughal, Farah, Swainston, Neil, Wright-Muelas, Marina, Burgess-Brown, Nicola, Carpenter, Liz, Dürr, Katharina, Hansen, Jesper, Scacioc, Andreea, Colas, Claire, Digles, Daniela, Ecker, Gerhard, Füzi, Barbara, Gamsjäger, Viktoria, Grandits, Melanie, Martini, Riccardo, Troger, Florentina, Altermatt, Patrick, Doucerain, Cédric, Dürrenberger, Franz, Manolova, Vania, Steck, Anna-Lena, Sundström, Hanna, Wilhelm, Maria, Steppan, Claire M.

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Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists von Orsi, Douglas L., Ferrara, Steven J., Siegel, Stephan, Friberg, Anders, Bouché, Léa, Pook, Elisabeth, Lienau, Philip, Bluck, Joseph P., Lemke, Christopher T., Akcay, Gizem, Stellfeld, Timo, Meyer, Hanna, Pütter, Vera, Holton, Simon J., Korr, Daniel, Jerchel-Furau, Isabel, Pantelidou, Constantia, Strathdee, Craig A., Meyerson, Matthew, Eis, Knut, Goldstein, Jonathan T.

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Mouse pre-replicative complex proteins colocalise and interact with the centrosome von Stuermer, Andrea, Hoehn, Karsten, Faul, Thomas, Auth, Tanja, Brand, Normen, Kneissl, Margot, Pütter, Vera, Grummt, Friedrich

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Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin von Bandeiras, Tiago M., Hillig, Roman Christian, Matias, Pedro M., Eberspaecher, Uwe, Fanghänel, Jörg, Thomaz, Mónica, Miranda, Sandra, Crusius, Kerstin, Pütter, Vera, Amstutz, Patrick, Gulotti-Georgieva, Maya, Binz, H. Kaspar, Holz, Caterina, Schmitz, Arndt A. P., Lang, Christine, Donner, Peter, Egner, Ursula, Carrondo, Maria A., Müller-Tiemann, Beate

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ACYL SULFONAMIDES FOR TREATING CANCER von GRADL, STEFAN NIKOLAUS, FERNANDEZ-MONTALVAN, AMAURY ERNESTO, NEUHAUS, ROLAND, KORR, DANIEL, PUTTER, VERA, GORJANACZ, MATYAS, FERRARA, STEVEN JAMES, JAFFE, JACOB D, TER LAAK, ANTONIUS, HILLIG, ROMAN, BOUCHE, LEA AURELIE, BARAK, NAOMI, STRATHDEE, CRAIG, HERBERT, SIMON ANTHONY

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Expression and Characterization of Relaxin Family Peptide Receptor 1 Variants von Speck, David, Kleinau, Gunnar, Meininghaus, Mark, Erbe, Antje, Einfeldt, Alexandra, Szczepek, Michal, Scheerer, Patrick, Pütter, Vera

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SUBSTITUTED BENZYLINDAZOLES FOR USE AS BUB1 KINASE INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES von MENGEL Anne, PREUSSE Cornelia, HITCHCOCK Marion, FANGHANEL Jorg, GNOTH Mark Jean, BRIEM Hans, SCHULZE Volker, PRECHTL Stefan, LIENAU Philip, SIEMEISTER Gerhard, PUTTER Vera, FERNANDEZ-MONTALVAN Amaury Ernesto, EIS Knut, WENGNER Antje Margret, HOLTON Simon

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