Urinary Exosomal miRNA Signature in Type II Diabetic Nephropathy Patients von Delić, Denis, Eisele, Claudia, Schmid, Ramona, Baum, Patrick, Wiech, Franziska, Gerl, Martin, Zimdahl, Heike, Pullen, Steven S, Urquhart, Richard

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Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments von Sheng, Xin, Guan, Yuting, Ma, Ziyuan, Wu, Junnan, Liu, Hongbo, Qiu, Chengxiang, Vitale, Steven, Miao, Zhen, Seasock, Matthew J., Palmer, Matthew, Shin, Myung K., Duffin, Kevin L., Pullen, Steven S., Edwards, Todd L., Hellwege, Jacklyn N., Hung, Adriana M., Li, Mingyao, Voight, Benjamin F., Coffman, Thomas M., Brown, Christopher D., Susztak, Katalin

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The key role of NLRP3 and STING in APOL1-associated podocytopathy von Wu, Junnan, Raman, Archana, Coffey, Nathan J, Sheng, Xin, Wahba, Joseph, Seasock, Matthew J, Ma, Ziyuan, Beckerman, Pazit, Laczkó, Dorottya, Palmer, Matthew B, Kopp, Jeffrey B, Kuo, Jay J, Pullen, Steven S, Boustany-Kari, Carine M, Linkermann, Andreas, Susztak, Katalin

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Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice von Beckerman, Pazit, Bi-Karchin, Jing, Park, Ae Seo Deok, Qiu, Chengxiang, Dummer, Patrick D, Soomro, Irfana, Boustany-Kari, Carine M, Pullen, Steven S, Miner, Jeffrey H, Hu, Chien-An A, Rohacs, Tibor, Inoue, Kazunori, Ishibe, Shuta, Saleem, Moin A, Palmer, Matthew B, Cuervo, Ana Maria, Kopp, Jeffrey B, Susztak, Katalin

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In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease von Lin, Brian Leei, Matera, Damian, Doerner, Julia F., Zheng, Nan, del Camino, Donato, Mishra, Sumita, Bian, Hong, Zeveleva, Svetlana, Zhen, Xiaoguang, Blair, Nathaniel T., Chong, Jayhong A., Hessler, David P., Bedja, Djahida, Zhu, Guangshuo, Muller, Grace K., Ranek, Mark J., Pantages, Lynn, McFarland, Mary, Netherton, Matthew R., Berry, Angela, Wong, Diane, Rast, Georg, Qian, Hu Sheng, Weldon, Steven M., Kuo, Jay J., Sauer, Achim, Sarko, Chris, Moran, Magdalene M., Kass, David A., Pullen, Steven S.

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Renal compartment–specific genetic variation analyses identify new pathways in chronic kidney disease von Qiu, Chengxiang, Huang, Shizheng, Park, Jihwan, Park, YoSon, Ko, Yi-An, Seasock, Matthew J., Bryer, Joshua S., Xu, Xiang-Xi, Song, Wen-Chao, Palmer, Matthew, Hill, Jon, Guarnieri, Paolo, Hawkins, Julie, Boustany-Kari, Carine M., Pullen, Steven S., Brown, Christopher D., Susztak, Katalin

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Deep learning-based quantification of NAFLD/NASH progression in human liver biopsies von Heinemann, Fabian, Gross, Peter, Zeveleva, Svetlana, Qian, Hu Sheng, Hill, Jon, Höfer, Anne, Jonigk, Danny, Diehl, Anna Mae, Abdelmalek, Manal, Lenter, Martin C., Pullen, Steven S., Guarnieri, Paolo, Stierstorfer, Birgit

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The senescence-associated secretome of Hedgehog-deficient hepatocytes drives MASLD progression von Jun, Ji Hye, Du, Kuo, Dutta, Rajesh Kumar, Maeso-Diaz, Raquel, Oh, Seh Hoon, Wang, Liuyang, Gao, Guannan, Ferreira, Ana, Hill, Jon, Pullen, Steven S, Diehl, Anna Mae

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The Novel, Clinical-Stage Soluble Guanylate Cyclase Activator BI 685509 Protects from Disease Progression in Models of Renal Injury and Disease von Reinhart, Glenn A., Harrison, Paul C., Lincoln, Kathleen, Chen, Hongxing, Sun, Peng, Hill, Jon, Qian, Hu Sheng, McHugh, Mark C., Clifford, Holly, Ng, Khing Jow, Wang, Hong, Fowler, Danielle, Gueneva-Boucheva, Kristina, Brenneman, Jehrod B., Bosanac, Todd, Wong, Diane, Fryer, Ryan M., Sarko, Chris, Boustany-Kari, Carine M., Pullen, Steven S.

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Single-cell multi-omic and spatial profiling of human kidneys implicates the fibrotic microenvironment in kidney disease progression von Abedini, Amin, Levinsohn, Jonathan, Klötzer, Konstantin A., Dumoulin, Bernhard, Ma, Ziyuan, Frederick, Julia, Dhillon, Poonam, Balzer, Michael S., Shrestha, Rojesh, Liu, Hongbo, Vitale, Steven, Bergeson, Andi M., Devalaraja-Narashimha, Kishor, Grandi, Paola, Bhattacharyya, Tanmoy, Hu, Erding, Pullen, Steven S., Boustany-Kari, Carine M., Guarnieri, Paolo, Karihaloo, Anil, Traum, Daniel, Yan, Hanying, Coleman, Kyle, Palmer, Matthew, Sarov-Blat, Lea, Morton, Lori, Hunter, Christopher A., Kaestner, Klaus H., Li, Mingyao, Susztak, Katalin

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A Soluble Guanylate Cyclase Activator Inhibits the Progression of Diabetic Nephropathy in the ZSF1 Rat von Boustany-Kari, Carine M, Harrison, Paul C, Chen, Hongxing, Lincoln, Kathleen A, Qian, Hu Sheng, Clifford, Holly, Wang, Hong, Zhang, Xiaomei, Gueneva-Boucheva, Kristina, Bosanac, Todd, Wong, Diane, Fryer, Ryan M, Richman, Jeremy G, Sarko, Chris, Pullen, Steven S

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Pharmacological TRPC6 inhibition improves survival and muscle function in mice with Duchenne muscular dystrophy von Lin, Brian L, Shin, Joseph Y, Jeffreys, William Pd, Wang, Nadan, Lukban, Clarisse A, Moorer, Megan C, Velarde, Esteban, Hanselman, Olivia A, Kwon, Seoyoung, Kannan, Suraj, Riddle, Ryan C, Ward, Christopher W, Pullen, Steven S, Filareto, Antonio, Kass, David A

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Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies von Taylor, Steven J, Padyana, Anil K, Abeywardane, Asitha, Liang, Shuang, Hao, Ming-Hong, De Lombaert, Stéphane, Proudfoot, John, Farmer, Bennett S, Li, Xiang, Collins, Brandon, Martin, Leslie, Albaugh, Daniel R, Hill-Drzewi, Melissa, Pullen, Steven S, Takahashi, Hidenori

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Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease von Chen, Tianyi, Dalton, George, Oh, Seh-Hoon, Maeso-Diaz, Raquel, Du, Kuo, Meyers, Rachel A., Guy, Cynthia, Abdelmalek, Manal F., Henao, Ricardo, Guarnieri, Paolo, Pullen, Steven S., Gregory, Simon, Locker, Joseph, Brown, J. Mark, Diehl, Anna Mae

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Modulation of vascular contraction via soluble guanylate cyclase signaling in a novel ex vivo method using rat precision‐cut liver slices von Oldenburger, Anouk, Birk, Gerald, Schlepütz, Marco, Broermann, Andre, Stierstorfer, Birgit, Pullen, Steven S., Rippmann, Jörg F.

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Three Mechanistically Distinct Kinase Assays Compared: Measurement of Intrinsic ATPase Activity Identified the Most Comprehensive Set of ITK Inhibitors von Kashem, Mohammed A., Nelson, Richard M., Yingling, Jeffrey D., Pullen, Steven S., Prokopowicz, III, Anthony S., Jones, Jessi Wildeson, Wolak, John P., Rogers, George R., Morelock, Maurice M., Snow, Roger J., Homon, Carol Ann, Jakes, Scott

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The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells von Noelle, Randolph J, Ahonen, Cory L, Manning, Eric M, Erickson, Loren D, O'Connor, Brian P, Lind, Evan F, Pullen, Steven S, Kehry, Marilyn R

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Crystallographic Analysis of CD40 Recognition and Signaling by Human TRAF2 von McWhirter, Sarah M., Pullen, Steven S., Holton, James M., Crute, James J., Kehry, Marilyn R., Alber, Tom

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Single‐cell RNA sequencing data identify a conserved population of metallothionein‐expressing macrophages that may be ubiquitous in vital human organs von Daccache, Joseph A., Eng, Francis, Cao, Lei, Ma, Ning, Ward, Stephen C., Schiano, Thomas, Miller, Mark, Herron, Daniel, Azzara, Anthony V., Pullen, Steven S., Guarnieri, Paolo, Aloman, Costica, Branch, Andrea D.

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CD40−Tumor Necrosis Factor Receptor-Associated Factor (TRAF) Interactions:  Regulation of CD40 Signaling through Multiple TRAF Binding Sites and TRAF Hetero-Oligomerization von Pullen, Steven S, Miller, Heather G, Everdeen, Daniel S, Dang, Thu T. A, Crute, James J, Kehry, Marilyn R

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