The Evolving Mechanisms of Action of Glatiramer Acetate von Prod'homme, Thomas, Zamvil, Scott S

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MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies von Molnarfi, Nicolas, Schulze-Topphoff, Ulf, Weber, Martin S, Patarroyo, Juan C, Prod'homme, Thomas, Varrin-Doyer, Michel, Shetty, Aparna, Linington, Christopher, Slavin, Anthony J, Hidalgo, Juan, Jenne, Dieter E, Wekerle, Hartmut, Sobel, Raymond A, Bernard, Claude C A, Shlomchik, Mark J, Zamvil, Scott S

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Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation von Ryu, Jae Kyu, Petersen, Mark A., Murray, Sara G., Baeten, Kim M., Meyer-Franke, Anke, Chan, Justin P., Vagena, Eirini, Bedard, Catherine, Machado, Michael R., Coronado, Pamela E. Rios, Prod'homme, Thomas, Charo, Israel F., Lassmann, Hans, Degen, Jay L., Zamvil, Scott S., Akassoglou, Katerina

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In vivo programmed myeloid cells expressing novel chimeric antigen receptors show potent anti-tumor activity in preclinical solid tumor models von Argueta, Shannon, Wang, Yuxiao, Zhao, Hongyun, Diwanji, Neha, Gorgievski, Michael, Cochran, Edward, Grudzien-Nogalska, Ewa, D'Alessandro, Josephine, McCreedy, Bruce, Prod'homme, Thomas, Hofmeister, Robert, Ding, Jian, Getts, Daniel

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SLAT/Def6 Plays a Critical Role in the Development of Th17 Cell-Mediated Experimental Autoimmune Encephalomyelitis von Canonigo-Balancio, Ann J, Fos, Camille, Prod'homme, Thomas, Becart, Stephane, Altman, Amnon

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Neither T-helper type 2 nor Foxp3+ regulatory T cells are necessary for therapeutic benefit of atorvastatin in treatment of central nervous system autoimmunity von Weber, Martin S, Prod'homme, Thomas, Youssef, Sawsan, Dunn, Shannon E, Steinman, Lawrence, Zamvil, Scott S

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Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity von Stüve, Olaf, Youssef, Sawsan, Weber, Martin S, Nessler, Stefan, von Büdingen, Hans-Christian, Hemmer, Bernhard, Prod'homme, Thomas, Sobel, Raymond A, Steinman, Lawrence, Zamvil, Scott S

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Statins in the treatment of central nervous system autoimmune disease von Weber, Martin S., Youssef, Sawsan, Dunn, Shannon E., Prod'homme, Thomas, Neuhaus, Oliver, Stuve, Olaf, Greenwood, John, Steinman, Lawrence, Zamvil, Scott S.

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The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis von Onizawa, Michio, Oshima, Shigeru, Schulze-Topphoff, Ulf, Oses-Prieto, Juan A, Lu, Timothy, Tavares, Rita, Prodhomme, Thomas, Duong, Bao, Whang, Michael I, Advincula, Rommel, Agelidis, Alex, Barrera, Julio, Wu, Hao, Burlingame, Alma, Malynn, Barbara A, Zamvil, Scott S, Ma, Averil

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Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor von Farutin, Victor, Prod'homme, Thomas, McConnell, Kevin, Washburn, Nathaniel, Halvey, Patrick, Etzel, Carol J, Guess, Jamey, Duffner, Jay, Getchell, Kristen, Meccariello, Robin, Gutierrez, Bryan, Honan, Christopher, Zhao, Ganlin, Cilfone, Nicholas A, Gunay, Nur Sibel, Hillson, Jan L, DeLuca, David S, Saunders, Katherine C, Pappas, Dimitrios A, Greenberg, Jeffrey D, Kremer, Joel M, Manning, Anthony M, Ling, Leona E, Capila, Ishan

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Glatiramer acetate treatment negatively regulates type I interferon signaling von Molnarfi, Nicolas, Prodʼhomme, Thomas, Schulze-Topphoff, Ulf, Spencer, Collin M, Weber, Martin S, Patarroyo, Juan C, Lalive, Patrice H, Zamvil, Scott S

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Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE von Shetty, Aparna, Gupta, Sheena G, Varrin-Doyer, Michel, Weber, Martin S, Prodʼhomme, Thomas, Molnarfi, Nicolas, Ji, Niannian, Nelson, Patricia A, Patarroyo, Juan C, Schulze-Topphoff, Ulf, Fogal, Stephen E, Forsthuber, Thomas, Sobel, Raymond A, Bernard, Claude C.A, Slavin, Anthony J, Zamvil, Scott S

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B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity von Weber, Martin S., Prod'homme, Thomas, Patarroyo, Juan C., Molnarfi, Nicolas, Karnezis, Tara, Lehmann-Horn, Klaus, Danilenko, Dimitry M., Eastham-Anderson, Jeffrey, Slavin, Anthony J., Linington, Christopher, Bernard, Claude C. A., Martin, Flavius, Zamvil, Scott S.

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Type II monocytes modulate T cell–mediated central nervous system autoimmune disease von Weber, Martin S, Prod'homme, Thomas, Youssef, Sawsan, Dunn, Shannon E, Rundle, Cynthia D, Lee, Linda, Patarroyo, Juan C, Stüve, Olaf, Sobel, Raymond A, Steinman, Lawrence, Zamvil, Scott S

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Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation[S] von Washburn, Nathaniel, Meccariello, Robin, Duffner, Jay, Getchell, Kristen, Holte, Kimberly, Prod'homme, Thomas, Srinivasan, Karunya, Prenovitz, Robert, Lansing, Jonathan, Capila, Ishan, Kaundinya, Ganesh, Manning, Anthony M., Bosques, Carlos J.

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Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin von Dunn, Shannon E, Youssef, Sawsan, Goldstein, Matthew J, Prod'homme, Thomas, Weber, Martin S, Zamvil, Scott S, Steinman, Lawrence

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Abstract LB027: In vivo delivery of novel CD89 fusion receptor to myeloid cells by mRNA activates anti-tumor immunity von Prod'homme, Thomas E., Argueta, Shannon, Zhao, Hongyun, Gorgievski, Michael, Diwangi, Neha, Cochran, Edward, McCreedy, Bruce, Wang, Yuxiao, Getts, Daniel

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Abstract CT131: Initial preclinical and clinical experience of autologous engineered monocytes in T cell lymphoma patients von Gerber, Michele, Prod'homme, Thomas, Wang, Yuxiao, Kieffer-Kwon, Kyong-Rim, Diwanji, Neha, D'Alessandro, Josephine, Du, Xing, Cochran, Edward, Gorgievski, Michael, Ling, Zheng, King, Nicholas, Mukherjee, Siddhartha, Getts, Daniel

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Statins and their potential targets in multiple sclerosis therapy von Stüve, Olaf, Prod'homme, Thomas, Slavin, Anthony, Youssef, Sawsan, Dunn, Shannon, Steinman, Lawrence, Zamvil, Scott S

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Immunodominant T cell determinants of aquaporin-4, the autoantigen associated with neuromyelitis optica von Nelson, Patricia A, Khodadoust, Mojgan, Prodhomme, Thomas, Spencer, Collin, Patarroyo, Juan Carlos, Varrin-Doyer, Michel, Ho, Joseph D, Stroud, Robert M, Zamvil, Scott S

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