In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate von Wienen, Wolfgang, Stassen, Jean-Marie, Priepke, Henning, Ries, Uwe Joerg, Hauel, Norbert

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Structure-Based Design of Novel Potent Nonpeptide Thrombin Inhibitors von Hauel, Norbert H, Nar, Herbert, Priepke, Henning, Ries, Uwe, Stassen, Jean-Marie, Wienen, Wolfgang

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1,2-Diacetals:  A New Opportunity for Organic Synthesis von Ley, Steven V, Baeschlin, Daniel K, Dixon, Darren J, Foster, Alison C, Ince, Stuart J, Priepke, Henning W. M, Reynolds, Dominic J

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Effects of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate, on thrombus formation and bleeding time in rats von Wienen, Wolfgang, Stassen, Jean-Marie, Priepke, Henning, Ries, Uwe Joerg, Hauel, Norbert

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Mechanism of Human Telomerase Inhibition by BIBR1532, a Synthetic, Non-nucleosidic Drug Candidate von Pascolo, Emanuelle, Wenz, Christian, Lingner, Joachim, Hauel, Norbert, Priepke, Henning, Kauffmann, Iris, Garin-Chesa, Pilar, Rettig, Wolfgang J., Damm, Klaus, Schnapp, Andreas

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Heterocyclic thrombin inhibitors. Part 2: quinoxalinone derivatives as novel, potent antithrombotic agents von Ries, Uwe J., Priepke, Henning W.M., Hauel, Norbert H., Handschuh, Sandra, Mihm, Gerhard, Stassen, Jean M., Wienen, Wolfgang, Nar, Herbert

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A New Strategy for Oligosaccharide Assembly Exploiting Cyclohexane-1,2-diacetal Methodology: An Efficient Synthesis of a High Mannose Type Nonasaccharide von Grice, Peter, Ley, Steven V., Pietruszka, Jörg, Osborn, Helen M. I., Priepke, Henning W. M., Warriner, Stuart L.

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Structural Basis for Inhibition Promiscuity of Dual Specific Thrombin and Factor Xa Blood Coagulation Inhibitors von Nar, Herbert, Bauer, Margit, Schmid, Angela, Stassen, Jean-Marie, Wienen, Wolfgang, Priepke, Henning W.M, Kauffmann, Iris K, Ries, Uwe J, Hauel, Norbert H

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Discovery of VU6024578/BI02982816: An mGlu 1 Positive Allosteric Modulator with Efficacy in Preclinical Antipsychotic and Cognition Models von Reed, Carson W, Kalbfleisch, Jacob F, Turkett, Jeremy A, Trombley, Trevor A, Nastase, Anthony F, Spearing, Paul K, Haymer, Daniel H, Sarwar, Mohammad Moshin, Quitalig, Marc, Dickerson, Jonathan W, Blobaum, Annie L, Boutaud, Olivier, Voehringer, Patrizia, Schuelert, Niklas, Cho, Hyekyung P, Niswender, Colleen M, Rook, Jerri M, Priepke, Henning, Ursu, Daniel, Conn, P Jeffrey, Melancon, Bruce J, Lindsley, Craig W

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Discovery of VU6024578/BI02982816: An mGlu1 Positive Allosteric Modulator with Efficacy in Preclinical Antipsychotic and Cognition Models von Reed, Carson W., Kalbfleisch, Jacob F., Turkett, Jeremy A., Trombley, Trevor A., Nastase, Anthony F., Spearing, Paul K., Haymer, Daniel H., Sarwar, Mohammad Moshin, Quitalig, Marc, Dickerson, Jonathan W., Blobaum, Annie L., Boutaud, Olivier, Voehringer, Patrizia, Schuelert, Niklas, Cho, Hyekyung P., Niswender, Colleen M., Rook, Jerri M., Priepke, Henning, Ursu, Daniel, Conn, P. Jeffrey, Melancon, Bruce J., Lindsley, Craig W.

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Heterocyclic thrombin inhibitors. Part 1: design and synthesis of amidino-phenoxy quinoline derivatives von Ries, Uwe J., Priepke, Henning W.M., Hauel, Norbert H., Haaksma, Eric E.J., Stassen, Jean M., Wienen, Wolfgang, Nar, Herbert

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A Facile One-Pot Synthesis of a Trisaccharide Unit from the Common Polysaccharide Antigen of Group B Streptococci Using Cyclohexane-1, 2-diacetal (CDA) Protected Rhamnosides von Ley, Steven V., Priepke, Henning W. M.

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A highly selective telomerase inhibitor limiting human cancer cell proliferation von Damm, Klaus, Hemmann, Ulrike, Garin-Chesa, Pilar, Hauel, Norbert, Kauffmann, Iris, Priepke, Henning, Niestroj, Claudia, Daiber, Christine, Enenkel, Barbara, Guilliard, Bernd, Lauritsch, Ines, Müller, Elfriede, Pascolo, Emanuelle, Sauter, Gabriele, Pantic, Milena, Martens, Uwe M., Wenz, Christian, Lingner, Joachim, Kraut, Norbert, Rettig, Wolfgang J., Schnapp, Andreas

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The discovery of dabigatran etexilate von van Ryn, Joanne, Goss, Ashley, Hauel, Norbert, Wienen, Wolfgang, Priepke, Henning, Nar, Herbert, Clemens, Andreas

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Direct Protection of 1,2-Diols from α-Diketones von Douglas, Nina L., Ley, Steven V., Osborn, Helen M. I., Owen, Dafydd R., Priepke, Henning W. M., Warriner, Stuart L.

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Cyclohexane-1,2-diacetals (CDA): A New Protecting Group for Vicinal Diols in Carbohydrates von Ley, Steven V., Priepke, Henning W. M., Warrine, Stuart L.

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Preparation, structure, derivatisation and NMR data of cyclohexane-1,2-diacetal protected carbohydrates von Grice, Peter, Ley, Steven V., Pietruszka, Jörg, Priepke, Henning W. M., Warriner, Stuart L.

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Synthesis of the Nonamannan Residue of a Glycoprotein with High Mannose Content von Grice, Peter, Ley, Steven V., Pietruszka, Jörg, Priepke, Henning W. M.

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Effects of Dabigatran, a Direct Thrombin Inhibitor, as Compared to the Direct Factor Xa Inhibitors, Rivaroxaban and Apixaban, on Tissue Factor-Induced Human Platelet Aggregation in... von van Ryn, Joanne, Kink-Eiband, Monika, Hauel, Norbert, Priepke, Henning, Wienen, Wolfgang

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Comparison of the Antithrombotic Effectiveness of the Direct Thrombin Inhibitor, Dabigatran Etexilate, and Two Factor Xa Inhibitors in an A-V Shunt Model of Thrombosis in Rabbits von van Ryn, Joanne, Hauel, Norbert, Priepke, Henning, Gerlach, Kai, Schuler-Metz, Annette, Wienen, Wolfgang

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