Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease von Sato, Katsutoshi, Padgaonkar, Amol A., Baker, Stacey J., Cosenza, Stephen C., Rechkoblit, Olga, Subbaiah, D. R. C. Venkata, Domingo-Domenech, Josep, Bartkowski, Alison, Port, Elisa R., Aggarwal, Aneel K., Ramana Reddy, M. V., Irie, Hanna Y., Reddy, E. Premkumar

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TGFβ reprograms TNF stimulation of macrophages towards a non-canonical pathway driving inflammatory osteoclastogenesis von Xia, Yuhan, Inoue, Kazuki, Du, Yong, Baker, Stacey J., Reddy, E. Premkumar, Greenblatt, Matthew B., Zhao, Baohong

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A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling von Athuluri-Divakar, Sai Krishna, Vasquez-Del Carpio, Rodrigo, Dutta, Kaushik, Baker, Stacey J., Cosenza, Stephen C., Basu, Indranil, Gupta, Yogesh K., Reddy, M.V. Ramana, Ueno, Lynn, Hart, Jonathan R., Vogt, Peter K., Mulholland, David, Guha, Chandan, Aggarwal, Aneel K., Reddy, E. Premkumar

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JNK-signaling: A multiplexing hub in programmed cell death von Dhanasekaran, Danny N., Reddy, E. Premkumar

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Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia von Kotini, Andriana G., Chang, Chan-Jung, Chow, Arthur, Yuan, Han, Ho, Tzu-Chieh, Wang, Tiansu, Vora, Shailee, Solovyov, Alexander, Husser, Chrystel, Olszewska, Malgorzata, Teruya-Feldstein, Julie, Perumal, Deepak, Klimek, Virginia M., Spyridonidis, Alexandros, Rampal, Raajit K., Silverman, Lewis, Reddy, E. Premkumar, Papaemmanuil, Elli, Parekh, Samir, Greenbaum, Benjamin D., Leslie, Christina S., Kharas, Michael G., Papapetrou, Eirini P.

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Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation von Lieu, Yen K, Reddy, E. Premkumar

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Drugging the 'undruggable' cancer targets von Dang, Chi V., Reddy, E. Premkumar, Shokat, Kevan M., Soucek, Laura

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Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade von Yan, Chi, Saleh, Nabil, Yang, Jinming, Nebhan, Caroline A., Vilgelm, Anna E., Reddy, E. Premkumar, Roland, Joseph T., Johnson, Douglas B., Chen, Sheau-Chiann, Shattuck-Brandt, Rebecca L., Ayers, Gregory D., Richmond, Ann

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JAKs, STATs and Src kinases in hematopoiesis: Hematopoiesis von RANE, Sushil G, PREMKUMAR REDDY, E

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Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors von Reddy, M.V. Ramana, Billa, Vinay K., Pallela, Venkat R., Mallireddigari, Muralidhar R., Boominathan, Rengasamy, Gabriel, Jerome L., Reddy, E. Premkumar

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Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas von Divakar, S K A, Ramana Reddy, M V, Cosenza, S C, Baker, S J, Perumal, D, Antonelli, A C, Brody, J, Akula, B, Parekh, S, Premkumar Reddy, E

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Discovery of a Clinical Stage Multi-Kinase Inhibitor Sodium (E)-2-{2-Methoxy-5-[(2′,4′,6′-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): Synthesis, Structure–Ac... von Reddy, M. V. Ramana, Venkatapuram, Padmavathi, Mallireddigari, Muralidhar R, Pallela, Venkat R, Cosenza, Stephen C, Robell, Kimberly A, Akula, Balaiah, Hoffman, Benjamin S, Reddy, E. Premkumar

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ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent von Gumireddy, Kiranmai, Reddy, M.V. Ramana, Cosenza, Stephen C., Nathan, R. Boomi, Baker, Stacey J., Papathi, Nabisa, Jiang, Jiandong, Holland, James, Reddy, E. Premkumar

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Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies von Jatiani, Shashidhar S, Baker, Stacey J, Silverman, Lewis R, Reddy, E Premkumar

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Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression von Chen, Xu-Qiao, Barrero, Carlos A., Vasquez-Del Carpio, Rodrigo, Reddy, E. Premkumar, Fecchio, Chiara, Merali, Salim, Deglincerti, Alessia, Fang, Cheng, Rogers, Jack, Maccecchini, Maria L.

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Modulation of life and death by the TNF receptor superfamily von Baker, S J, Reddy, E P

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The myb gene family in cell growth, differentiation and apoptosis von Oh, I H, Reddy, E P

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B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development von Baker, Stacey J., Ma'ayan, Avi, Lieu, Yen K., John, Premila, Reddy, M. V. Ramana, Chen, Edward Y., Duan, Qiaonan, Snoeck, Hans-Willem, Reddy, E. Premkumar

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Rigosertib ameliorates the effects of oncogenic KRAS signaling in a murine model of myeloproliferative neoplasia von Baker, Stacey J, Cosenza, Stephen C, Ramana Reddy, M V, Premkumar Reddy, E

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Transforming growth factor‐β adaptor, β2‐spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancer von Baek, Hye Jung, Pishvaian, Michael J., Tang, Yi, Kim, Tae Hyun, Yang, Shaoxian, Zouhairi, Majed El, Mendelson, Jon, Shetty, Kirti, Kallakury, Bhaskar, Berry, Deborah L., Shin, Kyung Hwan, Mishra, Bibhuti, Reddy, E. Premkumar, Kim, Sang Soo, Mishra, Lopa

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