Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity von van Loosdregt, Jorg, Fleskens, Veerle, Fu, Juan, Brenkman, Arjan B., Bekker, Cornelis P.J., Pals, Cornelieke E.G.M., Meerding, Jenny, Berkers, Celia R., Barbi, Joseph, Gröne, Andrea, Sijts, Alice J.A.M., Maurice, Madelon M., Kalkhoven, Eric, Prakken, Berent J., Ovaa, Huib, Pan, Fan, Zaiss, Dietmar M.W., Coffer, Paul J.

Volltext

Canonical Wnt Signaling Negatively Modulates Regulatory T Cell Function von van Loosdregt, Jorg, Fleskens, Veerle, Tiemessen, Machteld M., Mokry, Michal, van Boxtel, Ruben, Meerding, Jenny, Pals, Cornelieke E.G.M., Kurek, Dorota, Baert, Miranda R.M., Delemarre, Eveline M., Gröne, Andrea, Koerkamp, Marianne J.A. Groot, Sijts, Alice J.A.M., Nieuwenhuis, Edward E.S., Maurice, Madelon M., van Es, Johan H., ten Berge, Derk, Holstege, Frank C., Staal, Frank J.T., Zaiss, Dietmar M.W., Prakken, Berent J., Coffer, Paul J.

Volltext

Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays von de Jager, Wilco, Bourcier, Katarzyna, Rijkers, Ger T, Prakken, Berent J, Seyfert-Margolis, Vicki

Volltext

Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression von Peeters, Janneke G.C., Vervoort, Stephin J., Tan, Sander C., Mijnheer, Gerdien, de Roock, Sytze, Vastert, Sebastiaan J., Nieuwenhuis, Edward E.S., van Wijk, Femke, Prakken, Berent J., Creyghton, Menno P., Coffer, Paul J., Mokry, Michal, van Loosdregt, Jorg

Volltext

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization von van Loosdregt, Jorg, Vercoulen, Yvonne, Guichelaar, Teun, Gent, Yoony Y.J., Beekman, Jeffrey M., van Beekum, Olivier, Brenkman, Arjan B., Hijnen, Dirk-Jan, Mutis, Tuna, Kalkhoven, Eric, Prakken, Berent J., Coffer, Paul J.

Volltext

Histone Deacetylase Inhibitors Suppress Inflammatory Activation of Rheumatoid Arthritis Patient Synovial Macrophages and Tissue von Grabiec, Aleksander M, Krausz, Sarah, de Jager, Wilco, Burakowski, Tomasz, Groot, Dion, Sanders, Marjolein E, Prakken, Berent J, Maslinski, Wlodzimierz, Eldering, Eric, Tak, Paul P, Reedquist, Kris A

Volltext

A mixed method study investigating the key translational competencies acquired during a challenge-based course von Kools, Farah R W, Fox, Christine M, Prakken, Berent J, van Rijen, Harold V M

Volltext

International online mentorship for translational researchers von Kools, Farah R W, Fox, Christine M, van Rijen, Harold V M, Prakken, Berent J

Volltext

Simultaneous Detection of 15 Human Cytokines in a Single Sample of Stimulated Peripheral Blood Mononuclear Cells von de Jager, Wilco, te Velthuis, Henk, Prakken, Berent J, Kuis, Wietse, Rijkers, Ger T

Volltext

Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies von de Jager, Wilco, Prakken, Berent J., Bijlsma, Johannes W.J., Kuis, Wietse, Rijkers, Ger T.

Volltext

Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: A possible mechanism for therapeutic modulation of T cells von van Loosdregt, Jorg, PhD, Spreafico, Roberto, PhD, Rossetti, Maura, PhD, Prakken, Berent J., MD, PhD, Lotz, Martin, MD, PhD, Albani, Salvatore, MD, PhD

Volltext

Increased presence of FOXP3+ regulatory T cells in inflamed muscle of patients with active juvenile dermatomyositis compared to peripheral blood von Vercoulen, Yvonne, Bellutti Enders, Felicitas, Meerding, Jenny, Plantinga, Maud, Elst, Elisabeth F, Varsani, Hemlata, van Schieveen, Christa, Bakker, Mette H, Klein, Mark, Scholman, Rianne C, Spliet, Wim, Ricotti, Valeria, Koenen, Hans J P M, de Weger, Roel A, Wedderburn, Lucy R, van Royen-Kerkhof, Annet, Prakken, Berent J

Volltext

STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass von de Jong, Petrus R, Schadenberg, Alvin W L, van den Broek, Theo, Beekman, Jeffrey M, van Wijk, Femke, Coffer, Paul J, Prakken, Berent J, Jansen, Nicolaas J G

Volltext

One size does not fit all: an exploratory interview study on how translational researchers navigate the current academic reward system von Kools, Farah R W, Fox, Christine M, Prakken, Berent J, van Rijen, Harold V M

Volltext

Differential cytokine profiles in juvenile idiopathic arthritis subtypes revealed by cluster analysis von van den Ham, Henk-Jan, de Jager, Wilco, Bijlsma, Johannes W. J., Prakken, Berent J., de Boer, Rob J.

Volltext

Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery von Algra, Selma O, Groeneveld, Kathelijne M, Schadenberg, Alvin W L, Haas, Felix, Evens, Fabiola C M, Meerding, Jenny, Koenderman, Leo, Jansen, Nicolaas J G, Prakken, Berent J

Volltext

Epitope-Specific Immunotherapy Induces Immune Deviation of Proinflammatory T Cells in Rheumatoid Arthritis von Prakken, Berent J., Samodal, Rodrigo, Le, Tho D., Giannoni, Francesca, Yung, Gisella Puga, Scavulli, John, Amox, Diane, Roord, Sarah, de Kleer, Isme, Bonnin, Dustan, Lanza, Paola, Berry, Charles, Massa, Margherita, Billetta, Rosario, Albani, Salvatore, Carson, Dennis A.

Volltext

Effectiveness of First‐Line Treatment With Recombinant Interleukin‐1 Receptor Antagonist in Steroid‐Naive Patients With New‐Onset Systemic Juvenile Idiopathic Arthritis: Results of... von Vastert, Sebastiaan J., Jager, Wilco, Noordman, Bo Jan, Holzinger, Dirk, Kuis, Wietse, Prakken, Berent J., Wulffraat, Nico M.

Volltext

How does age determine the development of human immune-mediated arthritis? von Degboe, Yannick, Vastert, Sebastiaan J., Prakken, Berent J., McInnes, Iain B.

Volltext

PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation von Petrelli, Alessandra, Mijnheer, Gerdien, Hoytema van Konijnenburg, David P, van der Wal, Maria M, Giovannone, Barbara, Mocholi, Enric, Vazirpanah, Nadia, Broen, Jasper C, Hijnen, Dirkjan, Oldenburg, Bas, Coffer, Paul J, Vastert, Sebastian J, Prakken, Berent J, Spierings, Eric, Pandit, Aridaman, Mokry, Michal, van Wijk, Femke

Volltext