Reporter cell assay for human CD33 validated by specific antibodies and human iPSC-derived microglia von Wißfeld, Jannis, Mathews, Mona, Mossad, Omar, Picardi, Paola, Cinti, Alessandro, Redaelli, Loredana, Pradier, Laurent, Brüstle, Oliver, Neumann, Harald

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Neural differentiation of embryonic stem cells in vitro: a road map to neurogenesis in the embryo von Abranches, Elsa, Silva, Margarida, Pradier, Laurent, Schulz, Herbert, Hummel, Oliver, Henrique, Domingos, Bekman, Evguenia

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Alzheimer's disease‐associated R47H TREM2 increases, but wild‐type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss von Popescu, Alma S., Butler, Claire A., Allendorf, David H., Piers, Thomas M., Mallach, Anna, Roewe, Julian, Reinhardt, Peter, Cinti, Alessandro, Redaelli, Loredana, Boudesco, Christophe, Pradier, Laurent, Pocock, Jennifer M., Thornton, Peter, Brown, Guy C.

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NF-L in cerebrospinal fluid and serum is a biomarker of neuronal damage in an inducible mouse model of neurodegeneration von Brureau, Anthony, Blanchard-Bregeon, Véronique, Pech, Catherine, Hamon, Stéphanie, Chaillou, Pascal, Guillemot, Jean-Claude, Barneoud, Pascal, Bertrand, Philippe, Pradier, Laurent, Rooney, Thomas, Schussler, Nathalie

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Participating in innovative medicines initiative funded neurodegenerative disorder projects-An impact analysis conducted as part of the NEURONET project von Hawksworth, Claire, Salih, Fatima, Cresswell, Katharine, Steukers, Lennert, Diaz, Carlos, Killin, Lewis, Pradier, Laurent, Bradshaw, Angela, Dawoud, Dalia

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Gene delivery of a modified antibody to Aβ reduces progression of murine Alzheimer's disease von Elmer, Bradford M, Swanson, Kurt A, Bangari, Dinesh S, Piepenhagen, Peter A, Roberts, Errin, Taksir, Tatyana, Guo, Lei, Obinu, Maria-Carmen, Barneoud, Pascal, Ryan, Susan, Zhang, Bailin, Pradier, Laurent, Yang, Zhi-Yong, Nabel, Gary J

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The Innovative Medicines Initiative neurodegeneration portfolio: From individual projects to collaborative networks von O'Rourke, Diana, Coll-Padrós, Nina, Bradshaw, Angela, Killin, Lewis, Pradier, Laurent, Georges, Jean, Dawoud, Dalia M., Steukers, Lennert, Diaz, Carlos

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High-throughput 3D whole-brain quantitative histopathology in rodents von Vandenberghe, Michel E., Hérard, Anne-Sophie, Souedet, Nicolas, Sadouni, Elmahdi, Santin, Mathieu D., Briet, Dominique, Carré, Denis, Schulz, Jocelyne, Hantraye, Philippe, Chabrier, Pierre-Etienne, Rooney, Thomas, Debeir, Thomas, Blanchard, Véronique, Pradier, Laurent, Dhenain, Marc, Delzescaux, Thierry

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Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics von Wang, Zemin, Jin, Ming, Hong, Wei, Liu, Wen, Reczek, David, Lagomarsino, Valentina N, Hu, Yuan, Weeden, Tim, Frosch, Matthew P, Young-Pearse, Tracy L, Pradier, Laurent, Selkoe, Dennis, Walsh, Dominic M

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Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's Disease von Schmitz, Christoph, Rutten, Bart P.F., Pielen, Andrea, Schäfer, Stephanie, Wirths, Oliver, Tremp, Günter, Czech, Christian, Blanchard, Veronique, Multhaup, Gerd, Rezaie, Payam, Korr, Hubert, Steinbusch, Harry W.M., Pradier, Laurent, Bayer, Thomas A.

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Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model von Do, Tuan-Minh, Capdevila, Cécile, Pradier, Laurent, Blanchard, Véronique, Lopez-Grancha, Mati, Schussler, Nathalie, Steinmetz, Anke, Beninga, Jochen, Boulay, Denis, Dugay, Philippe, Verdier, Patrick, Aubin, Nadine, Dargazanli, Gihad, Chaves, Catarina, Genet, Elisabeth, Lossouarn, Yves, Loux, Christophe, Michoux, François, Moindrot, Nicolas, Chanut, Franck, Gury, Thierry, Eyquem, Stéphanie, Valente, Delphine, Bergis, Olivier, Rao, Ercole, Lesuisse, Dominique

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Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice von Schuessel, Katrin, Schäfer, Stephanie, Bayer, Thomas A., Czech, Christian, Pradier, Laurent, Müller-Spahn, Franz, Müller, Walter E., Eckert, Anne

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SAR228810: an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA) von Pradier, Laurent, Blanchard-Brégeon, Véronique, Bohme, Andrees, Debeir, Thomas, Menager, Jean, Benoit, Patrick, Barneoud, Pascal, Taupin, Véronique, Bertrand, Philippe, Dugay, Philippe, Cameron, Béatrice, Shi, Yi, Naimi, Souad, Duchesne, Marc, Gagnaire, Marie, Weeden, Tim, Travaline, Tara, Reczek, David, Khiroug, Leonard, Slaoui, Mohamed, Brunel, Pascale, Fukuyama, Hidehiro, Ravetch, Jeffrey, Canton, Thierry, Cohen, Caroline

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The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation von Schulz, Herbert, Kolde, Raivo, Adler, Priit, Aksoy, Irène, Anastassiadis, Konstantinos, Bader, Michael, Billon, Nathalie, Boeuf, Hélène, Bourillot, Pierre-Yves, Buchholz, Frank, Dani, Christian, Doss, Michael Xavier, Forrester, Lesley, Gitton, Murielle, Henrique, Domingos, Hescheler, Jürgen, Himmelbauer, Heinz, Hübner, Norbert, Karantzali, Efthimia, Kretsovali, Androniki, Lubitz, Sandra, Pradier, Laurent, Rai, Meena, Reimand, Jüri, Rolletschek, Alexandra, Sachinidis, Agapios, Savatier, Pierre, Stewart, Francis, Storm, Mike P, Trouillas, Marina, Vilo, Jaak, Welham, Melanie J, Winkler, Johannes, Wobus, Anna M, Hatzopoulos, Antonis K

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Astrocytic calcium/zinc binding protein S100A6 over expression in Alzheimer's disease and in PS1/APP transgenic mice models von Boom, Alain, Pochet, Roland, Authelet, Michele, Pradier, Laurent, Borghgraef, Peter, Van Leuven, Fred, Heizmann, Claus W., Brion, Jean-Pierre

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ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease von Macé, Sandrine, Cousin, Emmanuelle, Ricard, Sylvain, Génin, Emmanuelle, Spanakis, Emmanuel, Lafargue-Soubigou, Carole, Génin, Bérengère, Fournel, Raphaël, Roche, Sandrine, Haussy, Gilles, Massey, Florence, Soubigou, Stéphane, Bréfort, Georges, Benoit, Patrick, Brice, Alexis, Campion, Dominique, Hollis, Melvyn, Pradier, Laurent, Benavides, Jésus, Deleuze, Jean-François

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Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1 von Boutajangout, Allal, Authelet, Michèle, Blanchard, Véronique, Touchet, N, Tremp, Gunter, Pradier, Laurent, Brion, Jean-Pierre

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Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer von BEMELMANS, A.-P, HORELLOU, P, PRADIER, L, BRUNET, I, COLIN, P, MALLET, J

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Microarray analysis of nonhuman primates: validation of experimental models in neurological disorders von Marvanová, Markéta, Ménager, Jean, Bezard, Erwan, Bontrop, Ronald E., Pradier, Laurent, Wong, Garry

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Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2α pathway von Mouton-Liger, François, Paquet, Claire, Dumurgier, Julien, Bouras, Constantin, Pradier, Laurent, Gray, Françoise, Hugon, Jacques

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