CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons von Tian, Ruilin, Gachechiladze, Mariam A., Ludwig, Connor H., Laurie, Matthew T., Hong, Jason Y., Nathaniel, Diane, Prabhu, Anika V., Fernandopulle, Michael S., Patel, Rajan, Abshari, Mehrnoosh, Ward, Michael E., Kampmann, Martin

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Functional annotation of lncRNA in high-throughput screening von Yip, Chi Wai, Sivaraman, Divya M, Prabhu, Anika V, Shin, Jay W

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A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1 von Prabhu, Anika V, Kang, Insung, De Pace, Raffaella, Wassif, Christopher A, Fujiwara, Hideji, Kell, Pamela, Jiang, Xuntian, Ory, Daniel S, Bonifacino, Juan S, Ward, Michael E, Porter, Forbes D

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The sterol-based transcriptional control of human 7-dehydrocholesterol reductase (DHCR7): Evidence of a cooperative regulatory program in cholesterol synthesis von Prabhu, Anika V., Sharpe, Laura J., Brown, Andrew J.

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Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis von Prabhu, Anika V., Luu, Winnie, Sharpe, Laura J., Brown, Andrew J.

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New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis von Howe, Vicky, Sharpe, Laura J., Prabhu, Anika V., Brown, Andrew J.

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DHCR7: A vital enzyme switch between cholesterol and vitamin D production von Prabhu, Anika V., Luu, Winnie, Li, Dianfan, Sharpe, Laura J., Brown, Andrew J.

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Navigating the Shallows and Rapids of Cholesterol Synthesis Downstream of HMGCR von SHARPE, Laura J., HOWE, Vicky, PRABHU, Anika V., LUU, Winnie, BROWN, Andrew J.

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Twin enzymes, divergent control: The cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post-translationally von Capell-Hattam, Isabelle M., Sharpe, Laura J., Qian, Lydia, Hart-Smith, Gene, Prabhu, Anika V., Brown, Andrew J.

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Phosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis von Prabhu, Anika V., Luu, Winnie, Sharpe, Laura J., Brown, Andrew J.

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Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features von Robbe, Pauline, Ridout, Kate E., Vavoulis, Dimitrios V., Dréau, Helene, Kinnersley, Ben, Denny, Nicholas, Chubb, Daniel, Appleby, Niamh, Cutts, Anthony, Cornish, Alex J., Lopez-Pascua, Laura, Clifford, Ruth, Burns, Adam, Stamatopoulos, Basile, Cabes, Maite, Alsolami, Reem, Antoniou, Pavlos, Oates, Melanie, Cavalieri, Doriane, Gibson, Jane, Prabhu, Anika V., Schwessinger, Ron, Jennings, Daisy, James, Terena, Maheswari, Uma, Duran-Ferrer, Martí, Carninci, Piero, Knight, Samantha J. L., Månsson, Robert, Hughes, Jim, Davies, James, Ross, Mark, Bentley, David, Strefford, Jonathan C., Devereux, Stephen, Pettitt, Andrew R., Hillmen, Peter, Caulfield, Mark J., Houlston, Richard S., Martín-Subero, José I., Schuh, Anna

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Antisense-oligonucleotide-mediated perturbation of long non-coding RNA reveals functional features in stem cells and across cell types von Yip, Chi Wai, Hon, Chung-Chau, Yasuzawa, Kayoko, Sivaraman, Divya M., Ramilowski, Jordan A., Shibayama, Youtaro, Agrawal, Saumya, Prabhu, Anika V., Parr, Callum, Severin, Jessica, Lan, Yan Jun, Dostie, Josée, Petri, Andreas, Nishiyori-Sueki, Hiromi, Tagami, Michihira, Itoh, Masayoshi, López-Redondo, Fernando, Kouno, Tsukasa, Chang, Jen-Chien, Luginbühl, Joachim, Kato, Masaki, Murata, Mitsuyoshi, Yip, Wing Hin, Shu, Xufeng, Abugessaisa, Imad, Hasegawa, Akira, Suzuki, Harukazu, Kauppinen, Sakari, Yagi, Ken, Okazaki, Yasushi, Kasukawa, Takeya, de Hoon, Michiel, Carninci, Piero, Shin, Jay W.

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Measuring Activity of Cholesterol Synthesis Enzymes Using Gas Chromatography/Mass Spectrometry von Prabhu, Anika V., Luu, Winnie, Brown, Andrew J.

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Twin enzymes, divergent control: The cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post‐translationally von Capell-Hattam, Isabelle Marie, Sharpe, Laura J., Qian, Lydia, Hart-Smith, Gene, Prabhu, Anika V., Brown, Andrew J.

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Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features von Robbe, Pauline, Ridout, Kate E, Vavoulis, Dimitrios V, Dréau, Helene, Kinnersley, Ben, Denny, Nicholas, Chubb, Daniel, Appleby, Niamh, Cutts, Anthony, Cornish, Alex J, Lopez-Pascua, Laura, Clifford, Ruth, Burns, Adam, Stamatopoulos, Basile, Cabes, Maite, Alsolami, Reem, Antoniou, Pavlos, Oates, Melanie, Cavalieri, Doriane, Genomics England Research Consortium, CLL pilot consortium, Gibson, Jane, Prabhu, Anika V, Schwessinger, Ron, Jennings, Daisy, James, Terena, Maheswari, Uma, Duran-Ferrer, Martí, Carninci, Piero, Knight, Samantha JL, Månsson, Robert, Hughes, Jim, Davies, James, Ross, Mark, Bentley, David, Strefford, Jonathan C, Devereux, Stephen, Pettitt, Andrew R, Hillmen, Peter, Caulfield, Mark J, Houlston, Richard S, Martín-Subero, José I, Schuh, Anna

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Additional file 3 of A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1 von Prabhu, Anika V., Kang, Insung, De Pace, Raffaella, Wassif, Christopher A., Fujiwara, Hideji, Kell, Pamela, Jiang, Xuntian, Ory, Daniel S., Bonifacino, Juan S., Ward, Michael E., Porter, Forbes D.

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Additional file 1 of A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1 von Prabhu, Anika V., Kang, Insung, De Pace, Raffaella, Wassif, Christopher A., Fujiwara, Hideji, Kell, Pamela, Jiang, Xuntian, Ory, Daniel S., Bonifacino, Juan S., Ward, Michael E., Porter, Forbes D.

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Additional file 2 of A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1 von Prabhu, Anika V., Kang, Insung, De Pace, Raffaella, Wassif, Christopher A., Fujiwara, Hideji, Kell, Pamela, Jiang, Xuntian, Ory, Daniel S., Bonifacino, Juan S., Ward, Michael E., Porter, Forbes D.

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Additional file 7 of A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1 von Prabhu, Anika V., Kang, Insung, De Pace, Raffaella, Wassif, Christopher A., Fujiwara, Hideji, Kell, Pamela, Jiang, Xuntian, Ory, Daniel S., Bonifacino, Juan S., Ward, Michael E., Porter, Forbes D.

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Additional file 6 of A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1 von Prabhu, Anika V., Kang, Insung, De Pace, Raffaella, Wassif, Christopher A., Fujiwara, Hideji, Kell, Pamela, Jiang, Xuntian, Ory, Daniel S., Bonifacino, Juan S., Ward, Michael E., Porter, Forbes D.

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