Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo von Pal, Anasuya C, Renard, Isaline, Singh, Pallavi, Vydyam, Pratap, Chiu, Joy E, Pou, Sovitj, Winter, Rolf W, Dodean, Rozalia, Frueh, Lisa, Nilsen, Aaron C, Riscoe, Michael K, Doggett, J Stone, Ben Mamoun, Choukri

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Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages von Ke, Hangjun, Ganesan, Suresh M, Dass, Swati, Morrisey, Joanne M, Pou, Sovitj, Nilsen, Aaron, Riscoe, Michael K, Mather, Michael W, Vaidya, Akhil B

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Discovery, Synthesis, and Optimization of Antimalarial 4(1H)‑Quinolone-3-Diarylethers von Nilsen, Aaron, Miley, Galen P, Forquer, Isaac P, Mather, Michael W, Katneni, Kasiram, Li, Yuexin, Pou, Sovitj, Pershing, April M, Stickles, Allison M, Ryan, Eileen, Kelly, Jane Xu, Doggett, J. Stone, White, Karen L, Hinrichs, David J, Winter, Rolf W, Charman, Susan A, Zakharov, Lev N, Bathurst, Ian, Burrows, Jeremy N, Vaidya, Akhil B, Riscoe, Michael K

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Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone von Lawres, Lauren A, Garg, Aprajita, Kumar, Vidya, Bruzual, Igor, Forquer, Isaac P, Renard, Isaline, Virji, Azan Z, Boulard, Pierre, Rodriguez, Eduardo X, Allen, Alexander J, Pou, Sovitj, Wegmann, Keith W, Winter, Rolf W, Nilsen, Aaron, Mao, Jialing, Preston, Douglas A, Belperron, Alexia A, Bockenstedt, Linda K, Hinrichs, David J, Riscoe, Michael K, Doggett, J Stone, Ben Mamoun, Choukri

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Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi von Silva, Marta G., Bastos, Reginaldo G., Stone Doggett, J., Riscoe, Michael K., Pou, Sovitj, Winter, Rolf, Dodean, Rozalia A., Nilsen, Aaron, Suarez, Carlos E.

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ELQ-331 as a prototype for extremely durable chemoprotection against malaria von Smilkstein, Martin J, Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A, Dodean, Rozalia A, Frueh, Lisa, Hinrichs, David J, Li, Yuexin, Martinson, Thomas, Munar, Myrna Y, Winter, Rolf W, Bruzual, Igor, Whiteside, Samantha, Nilsen, Aaron, Koop, Dennis R, Kelly, Jane X, Kappe, Stefan H I, Wilder, Brandon K, Riscoe, Michael K

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Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy von Stickles, Allison M, Ting, Li-Min, Morrisey, Joanne M, Li, Yuexin, Mather, Michael W, Meermeier, Erin, Pershing, April M, Forquer, Isaac P, Miley, Galen P, Pou, Sovitj, Winter, Rolf W, Hinrichs, David J, Kelly, Jane X, Kim, Kami, Vaidya, Akhil B, Riscoe, Michael K, Nilsen, Aaron

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Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifi... von McConnell, Erin V, Bruzual, Igor, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia A, Smilkstein, Martin J, Krollenbrock, Alina, Nilsen, Aaron, Zakharov, Lev N, Riscoe, Michael K, Doggett, J Stone

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Endochin-Like Quinolones Exhibit Promising Efficacy Against Neospora Caninum in vitro and in Experimentally Infected Pregnant Mice von Anghel, Nicoleta, Balmer, Vreni, Müller, Joachim, Winzer, Pablo, Aguado-Martinez, Adriana, Roozbehani, Mona, Pou, Sovitj, Nilsen, Aaron, Riscoe, Michael, Doggett, J Stone, Hemphill, Andrew

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Sontochin as a Guide to the Development of Drugs against Chloroquine-Resistant Malaria von POU, Sovitj, WINTER, Rolf W, NILSEN, Aaron, XU KELLY, Jane, YUEXIN LI, STONE DOGGETT, J, RISCOE, Erin W, WEGMANN, Keith W, HINRICHS, David J, RISCOE, Michael K

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Mechanism of Superoxide Generation by Neuronal Nitric-oxide Synthase von Pou, S, Keaton, L, Surichamorn, W, Rosen, G M

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The Role of Tetrahydrobiopterin in the Regulation of Neuronal Nitric-oxide Synthase-generated Superoxide von Rosen, Gerald M, Tsai, Pei, Weaver, John, Porasuphatana, Supatra, Roman, Linda J, Starkov, Anatoly A, Fiskum, Gary, Pou, Sovitj

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Esters of 5-Carboxyl-5-methyl-1-pyrroline N-Oxide:  A Family of Spin Traps for Superoxide von Tsai, Pei, Ichikawa, Kazuhiro, Mailer, Colin, Pou, Sovitj, Halpern, Howard J, Robinson, Bruce H, Nielsen, Robert, Rosen, Gerald M

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A fluorescence-based assay for measuring polyamine biosynthesis aminopropyl transferase–mediated catalysis von Singh, Pallavi, Choi, Jae-Yeon, Wang, Weiwei, T. Lam, Tukiet, Lechner, Philip, Vanderwal, Christopher D., Pou, Sovitj, Nilsen, Aaron, Ben Mamoun, Choukri

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Effective Therapy Targeting Cytochrome bc(1) Prevents Babesia Erythrocytic Development and Protects from Lethal Infection von Chiu, Joy E., Renard, Isaline, Pal, Anasuya C., Singh, Pallavi, Vydyam, Pratap, Thekkiniath, Jose, Kumar, Madelyn, Gihaz, Shalev, Pou, Sovitj, Winter, Rolf W., Dodean, Rozalia, Frueh, Lisa, Nilsen, Aaron C., Riscoe, Michael K., Doggett, J. Stone, Ben Mamoun, Choukri

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Influence of Conformation on the EPR Spectrum of 5,5-Dimethyl-1-hydroperoxy-1-pyrrolidinyloxyl:  A Spin Trapped Adduct of Superoxide von Rosen, Gerald M, Beselman, Aleksandra, Tsai, Pei, Pou, Sovitj, Mailer, Colin, Ichikawa, Kazuhiro, Robinson, Bruce H, Nielsen, Robert, Halpern, Howard J, MacKerell, Alexander D

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Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii von Alday, P Holland, Bruzual, Igor, Nilsen, Aaron, Pou, Sovitj, Winter, Rolf, Ben Mamoun, Choukri, Riscoe, Michael K, Doggett, J Stone

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Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil von van Schalkwyk, Donelly A., Riscoe, Michael K., Pou, Sovitj, Winter, Rolf W., Nilsen, Aaron, Duffey, Maelle, Moon, Robert W., Sutherland, Colin J.

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Superoxide Dismutase versus Ferricytochrome C:  Determining Rate Constants for the Spin Trapping of Superoxide by Cyclic Nitrones von Weaver, John, Tsai, Pei, Pou, Sovitj, Rosen, Gerald M

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Orally Bioavailable Endochin-Like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts von Doggett, J. Stone, Schultz, Tracey, Miller, Alyssa J., Bruzual, Igor, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia, Zakharov, Lev N., Nilsen, Aaron, Riscoe, Michael K., Carruthers, Vern B.

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