Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome von Kim, Woong, Bennett, Eric J., Huttlin, Edward L., Guo, Ailan, Li, Jing, Possemato, Anthony, Sowa, Mathew E., Rad, Ramin, Rush, John, Comb, Michael J., Harper, J. Wade, Gygi, Steven P.

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eIF2α controls memory consolidation via excitatory and somatostatin neurons von Sharma, Vijendra, Sood, Rapita, Khlaifia, Abdessattar, Eslamizade, Mohammad Javad, Hung, Tzu-Yu, Lou, Danning, Asgarihafshejani, Azam, Lalzar, Maya, Kiniry, Stephen J., Stokes, Matthew P., Cohen, Noah, Nelson, Alissa J., Abell, Kathryn, Possemato, Anthony P., Gal-Ben-Ari, Shunit, Truong, Vinh T., Wang, Peng, Yiannakas, Adonis, Saffarzadeh, Fatemeh, Cuello, A. Claudio, Nader, Karim, Kaufman, Randal J., Costa-Mattioli, Mauro, Baranov, Pavel V., Quintana, Albert, Sanz, Elisenda, Khoutorsky, Arkady, Lacaille, Jean-Claude, Rosenblum, Kobi, Sonenberg, Nahum

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Multiplexed Phosphoproteomic Profiling Using Titanium Dioxide and Immunoaffinity Enrichments Reveals Complementary Phosphorylation Events von Possemato, Anthony P, Paulo, Joao A, Mulhern, Daniel, Guo, Ailan, Gygi, Steven P, Beausoleil, Sean A

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Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway von Zhang, Junbing, Simpson, Claire M., Berner, Jacqueline, Chong, Harrison B., Fang, Jiafeng, Ordulu, Zehra, Weiss-Sadan, Tommy, Possemato, Anthony P., Harry, Stefan, Takahashi, Mariko, Yang, Tzu-yi, Richter, Marianne, Patel, Himani, Smith, Abby E., Carlin, Alexander D., Hubertus de Groot, Adriaan F., Wolf, Konstantin, Shi, Lei, Wei, Ting-Yu, Dürr, Benedikt R., Chen, Nicholas J., Vornbäumen, Tristan, Wichmann, Nina O., Mahamdeh, Mohammed S., Pooladanda, Venkatesh, Matoba, Yusuke, Kumar, Shaan, Kim, Eugene, Bouberhan, Sara, Oliva, Esther, Rueda, Bo R., Soberman, Roy J., Bardeesy, Nabeel, Liau, Brian B., Lawrence, Michael, Stokes, Matt P., Beausoleil, Sean A., Bar-Peled, Liron

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Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication von Yaron, Tomer M, Heaton, Brook E, Levy, Tyler M, Johnson, Jared L, Jordan, Tristan X, Cohen, Benjamin M, Kerelsky, Alexander, Lin, Ting-Yu, Liberatore, Katarina M, Bulaon, Danielle K, Van Nest, Samantha J, Koundouros, Nikos, Kastenhuber, Edward R, Mercadante, Marisa N, Shobana-Ganesh, Kripa, He, Long, Schwartz, Robert E, Chen, Shuibing, Weinstein, Harel, Elemento, Olivier, Piskounova, Elena, Nilsson-Payant, Benjamin E, Lee, Gina, Trimarco, Joseph D, Burke, Kaitlyn N, Hamele, Cait E, Chaparian, Ryan R, Harding, Alfred T, Tata, Aleksandra, Zhu, Xinyu, Tata, Purushothama Rao, Smith, Clare M, Possemato, Anthony P, Tkachev, Sasha L, Hornbeck, Peter V, Beausoleil, Sean A, Anand, Shankara K, Aguet, François, Getz, Gad, Davidson, Andrew D, Heesom, Kate, Kavanagh-Williamson, Maia, Matthews, David A, tenOever, Benjamin R, Cantley, Lewis C, Blenis, John, Heaton, Nicholas S

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Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells von Amiri, Mehdi, Kiniry, Stephen J., Possemato, Anthony P., Mahmood, Niaz, Basiri, Tayebeh, Dufour, Catherine R., Tabatabaei, Negar, Deng, Qiyun, Bellucci, Michael A., Harwalkar, Keerthana, Stokes, Matthew P., Giguère, Vincent, Kaufman, Randal J., Yamanaka, Yojiro, Baranov, Pavel V., Tahmasebi, Soroush, Sonenberg, Nahum

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Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases von Moritz, Albrecht, Li, Yu, Guo, Ailan, Villén, Judit, Wang, Yi, MacNeill, Joan, Kornhauser, Jon, Sprott, Kam, Zhou, Jing, Possemato, Anthony, Ren, Jian Min, Hornbeck, Peter, Cantley, Lewis C, Gygi, Steven P, Rush, John, Comb, Michael J

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Signaling networks assembled by oncogenic EGFR and c-Met von Guo, Ailan, Villén, Judit, Kornhauser, Jon, Lee, Kimberly A, Stokes, Matthew P, Rikova, Klarisa, Possemato, Anthony, Nardone, Julie, Innocenti, Gregory, Wetzel, Randall, Wang, Yi, MacNeill, Joan, Mitchell, Jeffrey, Gygi, Steven P, Rush, John, Polakiewicz, Roberto D, Comb, Michael J

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Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T von Zhang, Xiaodong, Guo, Ailan, Yu, Jianshi, Possemato, Anthony, Chen, Yueting, Zheng, Weiping, Polakiewicz, Roberto D, Kinzler, Kenneth W, Vogelstein, Bert, Velculescu, Victor E, Wang, Zhenghe John

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Craniofacial chondrogenesis in organoids from human stem cell-derived neural crest cells von Foltz, Lauren, Avabhrath, Nagashree, Lanchy, Jean-Marc, Levy, Tyler, Possemato, Anthony, Ariss, Majd, Peterson, Bradley, Grimes, Mark

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Abstract B197: Proteomic based analysis of ovarian cancer pathways von Rikova, Klarisa, Hall, Benjamin, Levy, Tyler, Possemato, Anthony, Wang, Yi, Lee, Kimberly, MacNeil, Joan, Guo, Ailan, Mulhern, Daniel, Keroack, Caroline, Ren, Jian M., Beausoleil, Sean A., Lonning, Scott, Comb, Michael J.

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Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer von Rikova, Klarisa, Guo, Ailan, Zeng, Qingfu, Possemato, Anthony, Yu, Jian, Haack, Herbert, Nardone, Julie, Lee, Kimberly, Reeves, Cynthia, Li, Yu, Hu, Yerong, Tan, Zhiping, Stokes, Matthew, Sullivan, Laura, Mitchell, Jeffrey, Wetzel, Randy, MacNeill, Joan, Ren, Jian Min, Yuan, Jin, Bakalarski, Corey E., Villen, Judit, Kornhauser, Jon M., Smith, Bradley, Li, Daiqiang, Zhou, Xinmin, Gygi, Steven P., Gu, Ting-Lei, Polakiewicz, Roberto D., Rush, John, Comb, Michael J.

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Disrupting Protein NEDDylation with MLN4924 Is a Novel Strategy to Target Cisplatin Resistance in Ovarian Cancer von NAWROCKI, Steffan T, KELLY, Kevin R, CAREW, Jennifer S, SMITH, Peter G, ESPITIA, Claudia M, POSSEMATO, Anthony, BEAUSOLEIL, Sean A, MILHOLLEN, Michael, BLAKEMORE, Stephen, THOMAS, Michael, BERGER, Allison

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Comprehensive quantitative proteomic profiling of the pharmacodynamic changes induced by MLN4924 in acute myeloid leukemia cells establishes rationale for its combination with azac... von Visconte, V, Nawrocki, S T, Espitia, C M, Kelly, K R, Possemato, A, Beausoleil, S A, Han, Y, Carraway, H E, Nazha, A, Advani, A S, Maciejewski, J P, Sekeres, M A, Carew, J S

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eIF2a controls memory consolidation via excitatory and somatostatin neurons von Sharma, Vijendra, Sood, Rapita, Khlaifia, Abdessattar, Eslamizade, Mohammad Javad, Hung, Tzu-Yu, Lou, Danning, Asgarihafshejani, Azam, Lalzar, Maya, Kiniry, Stephen J, Stokes, Matthew P, Cohen, Noah, Nelson, Alissa J, Abell, Kathryn, Possemato, Anthony P, Gal-Ben-Ari, Shunit, Truong, Vinh T, Wang, Peng, Yiannakas, Adonis, Saffarzadeh, Fatemeh, Cuello, A Claudio, Nader, Karim, Kaufman, Randal J, Costa-Mattioli, Mauro, Baranov, Pavel V, Quintana, Albert, Sanz, Elisenda, Khoutorsky, Arkady, Lacaille, Jean-Claude, Rosenblum, Kobi, Sonenberg, Nahum

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Abstract LB-067: Proteomic analysis identifies multi-dimensional deregulated signaling pathways in SCLC lung cancer von Rikova, Klarisa, Hall, Ben, Levy, Tyler, Possemato, Anthony, Aguiar, Mike, Beausoleil, Sean, Min Ren, Jian, Lee, Kimberly Lee, Lonning, Scott, Comb, Michael

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Comprehensive Quantitative Proteomic Profiling of the Pharmacodynamic Changes Induced By MLN4924 in Acute Myeloid Leukemia Cells Reveals Rational Targets for Combination Therapy von Visconte, Valeria, Nawrocki, Steffan T., Kelly, Kevin R., Han, Yingchun, Possemato, Anthony, Beausoleil, Sean, Nazha, Aziz, Maciejewski, Jaroslaw P., Carraway, Hetty E., Advani, Anjali S., Sekeres, Mikkael A., Carew, Jennifer S.

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Akt and 14-3-3 Control a PACS-2 Homeostatic Switch that Integrates Membrane Traffic with TRAIL-Induced Apoptosis von Aslan, Joseph E., You, Huihong, Williamson, Danielle M., Endig, Jessica, Youker, Robert T., Thomas, Laurel, Shu, Hongjun, Du, Yuhong, Milewski, Robert L., Brush, Matthew H., Possemato, Anthony, Sprott, Kam, Fu, Haian, Greis, Kenneth D., Runckel, Douglas N., Vogel, Arndt, Thomas, Gary

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Targeted Protein Degradation: Methods and Protocols von Cacace, Angela M, Hickey, Christopher M, Bekes, Miklos

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Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase non-receptor 14 von Zhang, Peng, Guo, Ailan, Possemato, Anthony, Wang, Chao, Beard, Lydia, Carlin, Cathleen, Markowitz, Sanford D., Polakiewicz, Roberto D., Wang, Zhenghe

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