Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine-elicited human sera von Muik, Alexander, Lui, Bonny Gaby, Wallisch, Ann-Kathrin, Bacher, Maren, Mühl, Julia, Reinholz, Jonas, Ozhelvaci, Orkun, Beckmann, Nina, Güimil Garcia, Ramón de la Caridad, Poran, Asaf, Shpyro, Svetlana, Finlayson, Andrew, Cai, Hui, Yang, Qi, Swanson, Kena A, Türeci, Özlem, Şahin, Uğur

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T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences von Madi, Asaf, Poran, Asaf, Shifrut, Eric, Reich-Zeliger, Shlomit, Greenstein, Erez, Zaretsky, Irena, Arnon, Tomer, Laethem, Francois Van, Singer, Alfred, Lu, Jinghua, Sun, Peter D, Cohen, Irun R, Friedman, Nir

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DNA methylation disruption reshapes the hematopoietic differentiation landscape von Izzo, Franco, Lee, Stanley C., Poran, Asaf, Chaligne, Ronan, Gaiti, Federico, Gross, Baptiste, Murali, Rekha R., Deochand, Sunil D., Ang, Chelston, Jones, Philippa Wyndham, Nam, Anna S., Kim, Kyu-Tae, Kothen-Hill, Steven, Schulman, Rafael C., Ki, Michelle, Lhoumaud, Priscillia, Skok, Jane A., Viny, Aaron D., Levine, Ross L., Kenigsberg, Ephraim, Abdel-Wahab, Omar, Landau, Dan A.

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Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells von Chen, Huanhuan Joyce, Poran, Asaf, Unni, Arun M, Huang, Sarah Xuelian, Elemento, Olivier, Snoeck, Hans-Willem, Varmus, Harold

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Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes von Poran, Asaf, Harjanto, Dewi, Malloy, Matthew, Arieta, Christina M, Rothenberg, Daniel A, Lenkala, Divya, van Buuren, Marit M, Addona, Terri A, Rooney, Michael S, Srinivasan, Lakshmi, Gaynor, Richard B

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Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T cell immunity von Muik, Alexander, Lui, Bonny Gaby, Quandt, Jasmin, Diao, Huitian, Fu, Yunguan, Bacher, Maren, Gordon, Jessica, Toker, Aras, Grosser, Jessica, Ozhelvaci, Orkun, Grikscheit, Katharina, Hoehl, Sebastian, Kohmer, Niko, Lustig, Yaniv, Regev-Yochay, Gili, Ciesek, Sandra, Beguir, Karim, Poran, Asaf, Vogler, Isabel, Türeci, Özlem, Sahin, Ugur

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Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum von Bancells, Cristina, Llorà-Batlle, Oriol, Poran, Asaf, Nötzel, Christopher, Rovira-Graells, Núria, Elemento, Olivier, Kafsack, Björn F. C., Cortés, Alfred

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Combined TCR Repertoire Profiles and Blood Cell Phenotypes Predict Melanoma Patient Response to Personalized Neoantigen Therapy plus Anti-PD-1 von Poran, Asaf, Scherer, Julian, Bushway, Meghan E., Besada, Rana, Balogh, Kristen N., Wanamaker, Amy, Williams, Reid G., Prabhakara, Jasmina, Ott, Patrick A., Hu-Lieskovan, Siwen, Khondker, Zakaria S., Gaynor, Richard B., Rooney, Michael S., Srinivasan, Lakshmi

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Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq von Redmond, David, Poran, Asaf, Elemento, Olivier

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364 A personal neoantigen vaccine NEO-PV-01 in combination with chemotherapy and pembrolizumab induces broad de novo immune responses in first line, non-squamous NSCLC von Awad, Mark, Spigel, David, Garon, Edward, Waqar, Saiama, Lisberg, Aaron, Moles, Melissa, Tepper, Jennifer, Lamb, April, Wanamaker, Amy, Khondker, Zakaria, Srouji, John, Dong, Jesse, Poran, Asaf, Balogh, Kristen, Bushway, Meghan, DeMario, Mark, Srinivasan, Lakshmi, Gaynor, Richard, Govindan, Ramaswamy

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BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans von Sahin, Ugur, Muik, Alexander, Vogler, Isabel, Derhovanessian, Evelyna, Kranz, Lena M., Vormehr, Mathias, Quandt, Jasmin, Bidmon, Nicole, Ulges, Alexander, Baum, Alina, Pascal, Kristen E., Maurus, Daniel, Brachtendorf, Sebastian, Lörks, Verena, Sikorski, Julian, Koch, Peter, Hilker, Rolf, Becker, Dirk, Eller, Ann-Kathrin, Grützner, Jan, Tonigold, Manuel, Boesler, Carsten, Rosenbaum, Corinna, Heesen, Ludwig, Kühnle, Marie-Cristine, Poran, Asaf, Dong, Jesse Z., Luxemburger, Ulrich, Kemmer-Brück, Alexandra, Langer, David, Bexon, Martin, Bolte, Stefanie, Palanche, Tania, Schultz, Armin, Baumann, Sybille, Mahiny, Azita J., Boros, Gábor, Reinholz, Jonas, Szabó, Gábor T., Karikó, Katalin, Shi, Pei-Yong, Fontes-Garfias, Camila, Perez, John L., Cutler, Mark, Cooper, David, Kyratsous, Christos A., Dormitzer, Philip R., Jansen, Kathrin U., Türeci, Özlem

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A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer von Ott, Patrick A., Hu-Lieskovan, Siwen, Chmielowski, Bartosz, Govindan, Ramaswamy, Naing, Aung, Bhardwaj, Nina, Margolin, Kim, Awad, Mark M., Hellmann, Matthew D., Lin, Jessica J., Friedlander, Terence, Bushway, Meghan E., Balogh, Kristen N., Sciuto, Tracey E., Kohler, Victoria, Turnbull, Samantha J., Besada, Rana, Curran, Riley R., Trapp, Benjamin, Scherer, Julian, Poran, Asaf, Harjanto, Dewi, Barthelme, Dominik, Ting, Ying Sonia, Dong, Jesse Z., Ware, Yvonne, Huang, Yuting, Huang, Zhengping, Wanamaker, Amy, Cleary, Lisa D., Moles, Melissa A., Manson, Kelledy, Greshock, Joel, Khondker, Zakaria S., Fritsch, Ed, Rooney, Michael S., DeMario, Mark, Gaynor, Richard B., Srinivasan, Lakshmi

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Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites von Poran, Asaf, Nötzel, Christopher, Aly, Omar, Mencia-Trinchant, Nuria, Harris, Chantal T., Guzman, Monica L., Hassane, Duane C., Elemento, Olivier, Kafsack, Björn F. C.

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Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction von Abelin, Jennifer G., Harjanto, Dewi, Malloy, Matthew, Suri, Prerna, Colson, Tyler, Goulding, Scott P., Creech, Amanda L., Serrano, Lia R., Nasir, Gibran, Nasrullah, Yusuf, McGann, Christopher D., Velez, Diana, Ting, Ying S., Poran, Asaf, Rothenberg, Daniel A., Chhangawala, Sagar, Rubinsteyn, Alex, Hammerbacher, Jeff, Gaynor, Richard B., Fritsch, Edward F., Greshock, Joel, Oslund, Rob C., Barthelme, Dominik, Addona, Terri A., Arieta, Christina M., Rooney, Michael S.

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Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer von Awad, Mark M., Govindan, Ramaswamy, Balogh, Kristen N., Spigel, David R., Garon, Edward B., Bushway, Meghan E., Poran, Asaf, Sheen, Joong Hyuk, Kohler, Victoria, Esaulova, Ekaterina, Srouji, John, Ramesh, Suchitra, Vyasamneni, Rohit, Karki, Binisha, Sciuto, Tracey E., Sethi, Himanshu, Dong, Jesse Z., Moles, Melissa A., Manson, Kelledy, Rooney, Michael S., Khondker, Zakaria S., DeMario, Mark, Gaynor, Richard B., Srinivasan, Lakshmi

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A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease von Zuiani, Adam, Dulberger, Charles L., De Silva, Nilushi S., Marquette, Meghan, Lu, Yu-Jung, Palowitch, Gavin M., Dokic, Anja, Sanchez-Velazquez, Ricardo, Schlatterer, Katja, Sarkar, Sanjay, Kar, Swagata, Chawla, Bhavna, Galeev, Alibek, Lindemann, Claudia, Rothenberg, Daniel A., Diao, Huitian, Walls, Alexandra C., Addona, Theresa A., Mensa, Federico, Vogel, Annette B., Stuart, Lynda M., van der Most, Robbert, Srouji, John R., Türeci, Özlem, Gaynor, Richard B., Şahin, Uğur, Poran, Asaf

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High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging von Xie, Xuanhua P., Laks, Dan R., Sun, Daochun, Poran, Asaf, Laughney, Ashley M., Wang, Zilai, Sam, Jessica, Belenguer, German, Fariñas, Isabel, Elemento, Olivier, Zhou, Xiuping, Parada, Luis F.

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The T-cell-directed vaccine BNT162b4 encoding conserved non-spike antigens protects animals from severe SARS-CoV-2 infection von Arieta, Christina M., Xie, Yushu Joy, Rothenberg, Daniel A., Diao, Huitian, Harjanto, Dewi, Meda, Shirisha, Marquart, Krisann, Koenitzer, Byron, Sciuto, Tracey E., Lobo, Alexander, Zuiani, Adam, Krumm, Stefanie A., Cadima Couto, Carla Iris, Hein, Stephanie, Heinen, André P., Ziegenhals, Thomas, Liu-Lupo, Yunpeng, Vogel, Annette B., Srouji, John R., Fesser, Stephanie, Thanki, Kaushik, Walzer, Kerstin, Addona, Theresa A., Türeci, Özlem, Şahin, Uğur, Gaynor, Richard B., Poran, Asaf

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Early computational detection of potential high-risk SARS-CoV-2 variants von Beguir, Karim, Skwark, Marcin J., Fu, Yunguan, Pierrot, Thomas, Carranza, Nicolas Lopez, Laterre, Alexandre, Kadri, Ibtissem, Korched, Abir, Lowegard, Anna U., Lui, Bonny Gaby, Sänger, Bianca, Liu, Yunpeng, Poran, Asaf, Muik, Alexander, Şahin, Uğur

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Single-Cell Transcriptome Profiling of Protozoan and Metazoan Parasites von Nötzel, Christopher, Poran, Asaf, Kafsack, Björn F.C.

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