ABL1-dependent OTULIN phosphorylation promotes genotoxic Wnt/β-catenin activation to enhance drug resistance in breast cancers von Wang, Wei, Li, Mingqi, Ponnusamy, Suriyan, Chi, Yayun, Xue, Jingyan, Fahmy, Beshoy, Fan, Meiyun, Miranda-Carboni, Gustavo A., Narayanan, Ramesh, Wu, Jiong, Wu, Zhao-Hui

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Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer von Ponnusamy, Suriyan, Coss, Christopher C, Thiyagarajan, Thirumagal, Watts, Kate, Hwang, Dong-Jin, He, Yali, Selth, Luke A, McEwan, Iain J, Duke, Charles B, Pagadala, Jayaprakash, Singh, Geetika, Wake, Robert W, Ledbetter, Christopher, Tilley, Wayne D, Moldoveanu, Tudor, Dalton, James T, Miller, Duane D, Narayanan, Ramesh

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Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation von Panneer Selvam, Shanmugam, De Palma, Ryan M, Oaks, Joshua J, Oleinik, Natalia, Peterson, Yuri K, Stahelin, Robert V, Skordalakes, Emmanuel, Ponnusamy, Suriyan, Garrett-Mayer, Elizabeth, Smith, Charles D, Ogretmen, Besim

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Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue von Ponnusamy, Suriyan, Tran, Quynh T, Harvey, Innocence, Smallwood, Heather S, Thiyagarajan, Thirumagal, Banerjee, Souvik, Johnson, Daniel L, Dalton, James T, Sullivan, Ryan D, Miller, Duane D, Bridges, Dave, Narayanan, Ramesh

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Therapeutic advances in hormone-dependent cancers: focus on prostate, breast and ovarian cancers von Ulm, Michael, Ramesh, Arvind V, McNamara, Keely M, Ponnusamy, Suriyan, Sasano, Hironobu, Narayanan, Ramesh

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Tissue Selective Androgen Receptor Modulators (SARMs) Increase Pelvic Floor Muscle Mass in Ovariectomized Mice von Ponnusamy, Suriyan, Sullivan, Ryan D., Thiyagarajan, Thirumagal, Tillmann, Heather, Getzenberg, Robert H., Narayanan, Ramesh

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Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1‐phosphate signalling to regulate tumour metastasis von Ponnusamy, Suriyan, Selvam, Shanmugam Panneer, Mehrotra, Shikhar, Kawamori, Toshihiko, Snider, Ashley J., Obeid, Lina M., Shao, Yuan, Sabbadini, Roger, Ogretmen, Besim

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Tricistronic expression of MOAP-1, Bax and RASSF1A in cancer cells enhances chemo-sensitization that requires BH3L domain of MOAP-1 von Lee, Yong Hoi, Pang, Siew Wai, Revai Lechtich, Esther, Shah, Khalid, Simon, Samson Eugin, Ponnusamy, Suriyan, Narayanan, Ramesh, Poh, Chit Laa, Tan, Kuan Onn

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Identification of a targetable JAK-STAT enriched androgen receptor and androgen receptor splice variant positive triple-negative breast cancer subtype von Asemota, Sarah, Effah, Wendy, Young, Kirsten L., Holt, Jeremiah, Cripe, Linnea, Ponnusamy, Suriyan, Thiyagarajan, Thirumagal, Hwang, Dong-Jin, He, Yali, Mcnamara, Keely, Johnson, Daniel, Wang, Yinan, Grimes, Brandy, Khosrosereshki, Yekta, Hollingsworth, T.J., Fleming, Martin D., Pritchard, Frances E., Hendrix, Ashley, Khan, Farhan, Fan, Meiyun, Makowski, Liza, Yin, Zheng, Sasano, Hironobu, Hayes, D. Neil, Pfeffer, Lawrence M., Miller, Duane D., Narayanan, Ramesh

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Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A von Salas, Arelis, Ponnusamy, Suriyan, Senkal, Can E., Meyers-Needham, Marisa, Selvam, Shanmugam Panneer, Saddoughi, Sahar A., Apohan, Elif, Sentelle, R. David, Smith, Charles, Gault, Christopher R., Obeid, Lina M., El-Shewy, Hesham M., Oaks, Joshua, Santhanam, Ramasamy, Marcucci, Guido, Baran, Yusuf, Mahajan, Sandeep, Fernandes, Daniel, Stuart, Robert, Perrotti, Danilo, Ogretmen, Besim

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Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy von Sentelle, R David, Senkal, Can E, Jiang, Wenhui, Ponnusamy, Suriyan, Gencer, Salih, Panneer Selvam, Shanmugam, Ramshesh, Venkat K, Peterson, Yuri K, Lemasters, John J, Szulc, Zdzislaw M, Bielawski, Jacek, Ogretmen, Besim

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Destroying the androgen receptor (AR)-potential strategy to treat advanced prostate cancer von Narayanan, Ramesh, Ponnusamy, Suriyan, Miller, Duane D

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Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas von Senkal, Can E, Ponnusamy, Suriyan, Rossi, Michael J, Bialewski, Jacek, Sinha, Debijyati, Jiang, James C, Jazwinski, S Michal, Hannun, Yusuf A, Ogretmen, Besim

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Racial Differences in Androgen Receptor (AR) and AR Splice Variants (AR-SVs) Expression in Treatment-Naïve Androgen-Dependent Prostate Cancer von Khan, Farhan, Anelo, Obianuju Mercy, Sadiq, Qandeel, Effah, Wendy, Price, Gary, Johnson, Daniel L, Ponnusamy, Suriyan, Grimes, Brandy, Morrison, Michelle L, Fowke, Jay H, Hayes, D Neil, Narayanan, Ramesh

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Androgen Receptor Is a Non-canonical Inhibitor of Wild-Type and Mutant Estrogen Receptors in Hormone Receptor-Positive Breast Cancers von Ponnusamy, Suriyan, Asemota, Sarah, Schwartzberg, Lee S., Guestini, Fouzia, McNamara, Keely M., Pierobon, Mariaelena, Font-Tello, Alba, Qiu, Xintao, Xie, Yingtian, Rao, Prakash K., Thiyagarajan, Thirumagal, Grimes, Brandy, Johnson, Daniel L., Fleming, Martin D., Pritchard, Frances E., Berry, Michael P., Oswaks, Roy, Fine, Richard E., Brown, Myles, Sasano, Hironobu, Petricoin, Emanuel F., Long, Henry W., Narayanan, Ramesh

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Neutral Sphingomyelinase-3 Is a DNA Damage and Nongenotoxic Stress-Regulated Gene That Is Deregulated in Human Malignancies von Corcoran, Chad A, He, Qin, Ponnusamy, Suriyan, Ogretmen, Besim, Huang, Ying, Sheikh, M Saeed

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Antiapoptotic roles of ceramide‐synthase‐6‐generated C 16 ‐ceramide via selective regulation of the ATF6/ CHOP arm of ER‐stress‐response pathways von Senkal, Can E., Ponnusamy, Suriyan, Bielawski, Jacek, Hannun, Yusuf A., Ogretmen, Besim

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Exploration and Biological Evaluation of Basic Heteromonocyclic Propanamide Derivatives as SARDs for the Treatment of Enzalutamide-Resistant Prostate Cancer von He, Yali, Hwang, Dong-Jin, Ponnusamy, Suriyan, Thiyagarajan, Thirumagal, Mohler, Michael L, Narayanan, Ramesh, Miller, Duane D

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An Overview of Next-Generation Androgen Receptor-Targeted Therapeutics in Development for the Treatment of Prostate Cancer von Mohler, Michael L, Sikdar, Arunima, Ponnusamy, Suriyan, Hwang, Dong-Jin, He, Yali, Miller, Duane D, Narayanan, Ramesh

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Antiapoptotic roles of ceramide-synthase-6-generated C₁₆-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways von Senkal, Can E, Ponnusamy, Suriyan, Bielawski, Jacek, Hannun, Yusuf A, Ogretmen, Besim

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