An anti-CD3/anti–CLL-1 bispecific antibody for the treatment of acute myeloid leukemia von Leong, Steven R., Sukumaran, Siddharth, Hristopoulos, Maria, Totpal, Klara, Stainton, Shannon, Lu, Elizabeth, Wong, Alfred, Tam, Lucinda, Newman, Robert, Vuillemenot, Brian R., Ellerman, Diego, Gu, Chen, Mathieu, Mary, Dennis, Mark S., Nguyen, Allen, Zheng, Bing, Zhang, Crystal, Lee, Genee, Chu, Yu-Waye, Prell, Rodney A., Lin, Kedan, Laing, Steven T., Polson, Andrew G.

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Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody-Drug Conjugates von Caculitan, Niña G, Dela Cruz Chuh, Josefa, Ma, Yong, Zhang, Donglu, Kozak, Katherine R, Liu, Yichin, Pillow, Thomas H, Sadowsky, Jack, Cheung, Tommy K, Phung, Qui, Haley, Benjamin, Lee, Byoung-Chul, Akita, Robert W, Sliwkowski, Mark X, Polson, Andrew G

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A Novel Anti-CD22 Anthracycline-Based Antibody-Drug Conjugate (ADC) That Overcomes Resistance to Auristatin-Based ADCs von Yu, Shang-Fan, Zheng, Bing, Go, MaryAnn, Lau, Jeff, Spencer, Susan, Raab, Helga, Soriano, Robert, Jhunjhunwala, Suchit, Cohen, Robert, Caruso, Michele, Polakis, Paul, Flygare, John, Polson, Andrew G

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An Anti-CLL-1 Antibody-Drug Conjugate for the Treatment of Acute Myeloid Leukemia von Zheng, Bing, Yu, Shang-Fan, Del Rosario, Geoffrey, Leong, Steven R, Lee, Genee Y, Vij, Rajesh, Chiu, Cecilia, Liang, Wei-Ching, Wu, Yan, Chalouni, Cecile, Sadowsky, Jack, Clark, Vanessa, Hendricks, Angela, Poon, Kirsten Achilles, Chu, Wayne, Pillow, Thomas, Schutten, Melissa M, Flygare, John, Polson, Andrew G

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Therapeutic potential of an anti-CD79b antibody–drug conjugate, anti–CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma von Dornan, David, Bennett, Fiona, Chen, Yvonne, Dennis, Mark, Eaton, Dan, Elkins, Kristi, French, Dorothy, Go, Mary Ann T., Jack, Andrew, Junutula, Jagath R., Koeppen, Hartmut, Lau, Jeffrey, McBride, Jacqueline, Rawstron, Andy, Shi, Xiaoyan, Yu, Nancy, Yu, Shang-Fan, Yue, Peng, Zheng, Bing, Ebens, Allen, Polson, Andrew G.

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Anti-CD79B Antibody-Drug Conjugate DCDS0780A in Patients with B-Cell Non-Hodgkin Lymphoma: Phase 1 Dose-Escalation Study von Herrera, Alex F, Patel, Manish R, Burke, John M, Advani, Ranjana, Cheson, Bruce D, Sharman, Jeff P, Penuel, Elicia, Polson, Andrew G, Liao, Chen Di, Li, Chunze, Schuth, Eva, Vaze, Anjali, Samineni, Divya, Elstrom, Rebecca, Cooper, James, Diefenbach, Catherine

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Development of T-cell engagers selective for cells co-expressing two antigens von Dicara, Danielle M, Bhakta, Sunil, Go, Mary Ann, Ziai, James, Firestein, Ron, Forrest, Bill, Gu, Chen, Leong, Steven R, Lee, Genee, Yu, Shang-Fan, Polson, Andrew G, Agard, Nicholas J

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Antibody-Drug Conjugates for the Treatment of Non-Hodgkin's Lymphoma: Target and Linker-Drug Selection von POLSON, Andrew G, CALEMINE-FENAUX, Jill, FRANTZ, Gretchen, FUJI, Reina N, GRAY, Alane, HARDEN, Kristin, INGLE, Gladys S, KLJAVIN, Noelyn M, KOEPPEN, Hartmut, NELSON, Christopher, PRABHU, Saileta, RAAB, Helga, CHAN, Pamela, ROSS, Sarajane, STEPHAN, Jean-Philippe, SCALES, Suzie J, SPENCER, Susan D, VANDLEN, Richard, WRANIK, Bernd, YU, Shang-Fan, BING ZHENG, EBENS, Allen, CHANG, Wesley, CHRISTENSEN, Erin, CLARK, Suzanna, DE SAUVAGE, Frederic J, EATON, Dan, ELKINS, Kristi, ELLIOTT, J. Michael

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A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma von Kakiuchi-Kiyota, Satoko, Ross, Thorsten, Wallweber, Heidi Ackerly, Kiefer, James R., Schutten, Melissa M., Adedeji, Adeyemi O., Cai, Hao, Hendricks, Robert, Cohen, Sivan, Myneni, Srividya, Liu, Luna, Fullerton, Aaron, Corr, Nicholas, Yu, Lanlan, de Almeida Nagata, Denise, Zhong, Shelly, Leong, Steven R., Li, Ji, Nakamura, Rin, Sumiyoshi, Teiko, Li, Jinze, Ovacik, Ayse Meric, Zheng, Bing, Dillon, Mike, Spiess, Christoph, Wingert, Susanne, Rajkovic, Erich, Ellwanger, Kristina, Reusch, Uwe, Polson, Andrew G.

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The cryptophycins as potent payloads for antibody drug conjugates von Verma, Vishal A., Pillow, Thomas H., DePalatis, Laura, Li, Guangmin, Phillips, Gail Lewis, Polson, Andrew G., Raab, Helga E., Spencer, Susan, Zheng, Bing

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Calicheamicin Antibody-Drug Conjugates with Improved Properties von Vollmar, Breanna S, Frantz, Chris, Schutten, Melissa M, Zhong, Fiona, Del Rosario, Geoffrey, Go, Mary Ann T, Yu, Shang-Fan, Leipold, Douglas D, Kamath, Amrita V, Ng, Carl, Xu, Keyang, Dela Cruz-Chuh, Josefa, Kozak, Katherine R, Chen, Jinhua, Xu, Zijin, Wai, John, Adhikari, Pragya, Erickson, Hans K, Dragovich, Peter S, Polson, Andrew G, Pillow, Thomas H

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The successes and limitations of preclinical studies in predicting the pharmacodynamics and safety of cell‐surface‐targeted biological agents in patients von Polson, Andrew G, Fuji, Reina N

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Evaluation and use of an anti‐cynomolgus monkey CD79b surrogate antibody–drug conjugate to enable clinical development of polatuzumab vedotin von Li, Dongwei, Lee, Donna, Dere, Randall C., Zheng, Bing, Yu, Shang‐Fan, Fuh, Franklin K., Kozak, Katherine R., Chung, Shan, Bumbaca Yadav, Daniela, Nazzal, Denise, Danilenko, Dimitry, Go, Mary Ann T., Williams, Marna, Polson, Andrew G., Poon, Kirsten Achilles, Prabhu, Saileta

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Expression pattern of the human FcRH/IRTA receptors in normal tissue and in B-chronic lymphocytic leukemia von Polson, Andrew G., Zheng, Bing, Elkins, Kristi, Chang, Wesley, Du, Changchun, Dowd, Patrick, Yen, Lulu, Tan, Christine, Hongo, Jo-Anne, Koeppen, Hartmut, Ebens, Allen

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Novel Anti-LY6G6D/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Colorectal Cancer von Wang, Peiyin, Sun, Liping L, Clark, Robyn, Hristopoulos, Maria, Chiu, Cecilia P C, Dillon, Michael, Lin, WeiYu, Lo, Amy A, Chalsani, Sreedevi, Das Thakur, Meghna, Zimmerman Savill, Kristin M, Rougé, Lionel, Lupardus, Patrick, Piskol, Robert, Husain, Bushra, Ellerman, Diego, Shivva, Vittal, Leong, Steven R, Ovacik, Meric, Totpal, Klara, Wu, Yan, Spiess, Christoph, Lee, Genee, Leipold, Douglas D, Polson, Andrew G

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An Anti-CD22- seco -CBI-Dimer Antibody-Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Prec... von Yu, Shang-Fan, Lee, Donna W, Zheng, Bing, Del Rosario, Geoffrey, Leipold, Douglas, Booler, Helen, Zhong, Fiona, Carrasco-Triguero, Montserrat, Hong, Kyu, Yan, Peter, Rowntree, Rebecca K, Schutten, Melissa M, Pillow, Thomas, Sadowsky, Jack D, Dragovich, Peter S, Polson, Andrew G

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DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma von Li, Dongwei, Poon, Kirsten Achilles, Yu, Shang-Fan, Dere, Randall, Go, MaryAnn, Lau, Jeffrey, Zheng, Bing, Elkins, Kristi, Danilenko, Dimitry, Kozak, Katherine R, Chan, Pamela, Chuh, Josefa, Shi, Xiaoyan, Nazzal, Denise, Fuh, Franklin, McBride, Jacqueline, Ramakrishnan, Vanitha, de Tute, Ruth, Rawstron, Andy, Jack, Andrew S, Deng, Rong, Chu, Yu-Waye, Dornan, David, Williams, Marna, Ho, William, Ebens, Allen, Prabhu, Saileta, Polson, Andrew G

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Targeting MCL‐1 and BCL‐2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non‐Hodgkin lymphoma: Results from preclinical models and a Phase Ib study... von Lasater, Elisabeth A., Amin, Dhara N., Bannerji, Rajat, Mali, Raghuveer Singh, Barrett, Kathy, Rys, Ryan N., Oeh, Jason, Lin, Eva, Sterne‐Weiler, Tim, Ingalla, Ellen Rei, Go, MaryAnn, Yu, Shang‐Fan, Krem, Maxwell M., Arthur, Chris, Hahn, Uwe, Johnston, Anna, Karur, Vinit, Khan, Nadia, Marlton, Paula, Phillips, Tycel, Gritti, Giuseppe, Seymour, John F., Tani, Monica, Yuen, Sam, Martin, Scott, Chang, Matthew T., Rose, Christopher M., Pham, Victoria C., Polson, Andrew G., Chang, YiMeng, Wever, Claudia, Johnson, Nathalie A., Jiang, Yanwen, Hirata, Jamie, Sampath, Deepak, Musick, Lisa, Flowers, Christopher R., Wertz, Ingrid E.

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T cell-Dependent Bispecific Therapy Enhances Innate Immune Activation and Antibody-Mediated Killing von Besla, Rickvinder, Penuel, Elicia, Del Rosario, Geoff, Cosino, Ely, Myrta, Szymon, Dillon, Mike, Lazar, Greg A, Nickles, Dorothee, Spiess, Christoph, Yu, Shang-Fan, Polson, Andrew G

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Intratumoral Payload Concentration Correlates with the Activity of Antibody-Drug Conjugates von Zhang, Donglu, Yu, Shang-Fan, Khojasteh, S Cyrus, Ma, Yong, Pillow, Thomas H, Sadowsky, Jack D, Su, Dian, Kozak, Katherine R, Xu, Keyang, Polson, Andrew G, Dragovich, Peter S, Hop, Cornelis E C A

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