Clinical Trial Designs for Cytostatic Agents: Are New Approaches Needed? von KORN, Edward L, ARBUCK, Susan G, PLUDA, James M, SIMON, Richard, KAPLAN, Richard S, CHRISTIAN, Michaele C

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Phase I Clinical Trial of Oral COL-3, a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer von RUDEK, Michelle A, FIGG, William D, DYER, Valerie, DAHUT, William, TURNER, Maria L, STEINBERG, Seth M, LIEWEHR, David J, KOHLER, David R, PLUDA, James M, REED, Eddie

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A Pilot Study of Cidofovir in Patients with Kaposi Sarcoma von Little, Richard F., Merced-Galindez, Florentino, Staskus, Katherine, Whitby, Denise, Aoki, Yoshiyasu, Humphrey, Rachel, Pluda, James M., Marshall, Vickie, Walters, Michael, Welles, Lauri, Rodriguez-Chavez, Isaac R., Pittaluga, Stefania, Tosato, Giovanna, Yarchoan, Robert

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A Randomized Phase II Trial of Thalidomide, an Angiogenesis Inhibitor, in Patients with Androgen-independent Prostate Cancer von FIGG, William D, DAHUT, William, CHEN, Clara C, DIXON, Shannon, KOHLER, David R, KRÜGER, Erwin A, GUBISH, Ed, PLUDA, James M, REED, Eddie, DURAY, Paul, HAMILTON, Michael, TOMPKINS, Anne, STEINBERG, Seth M, JONES, Elizabeth, PREMKUMAR, Ahalya, LINEHAN, W. Marston, FLOETER, Mary Kay

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Activity of Thalidomide in AIDS-Related Kaposi’s Sarcoma von LITTLE, R. F, WYVILL, K. M, WHITBY, D, GOEDERT, J. J, YARCHOAN, R, PLUDA, J. M, WELLES, L, MARSHALL, V, FIGG, W. D, NEWCOMB, F. M, TOSATO, G, FEIGAL, E, STEINBERG, S. M

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Phase II Trial of the Antiangiogenic Agent Thalidomide in Patients With Recurrent High-Grade Gliomas von FINE, H. A, FIGG, W. D, YUNG, W. K. A, JAECKLE, K, WEN, P. Y, KYRITSIS, A. P, LOEFFLER, J. S, LEVIN, V. A, BLACK, P. M, KAPLAN, R, PLUDA, J. M

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Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma von Little, Richard F., Pluda, James M., Wyvill, Kathleen M., Rodriguez-Chavez, Isaac R., Tosato, Giovanna, Catanzaro, Andrew T., Steinberg, Seth M., Yarchoan, Robert

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In vivo Activity against HIV and Favorable Toxicity Profile of 2$^{\prime}$,3$^{\prime}$-Dideoxyinosine von Yarchoan, Robert, Mitsuya, Hiroaki, Thomas, Rose V., Pluda, James M., Hartman, Neil R., Perno, Carlo-Federico, Marczyk, Kathy S., Allain, Jean-Pierre, Johns, David G., Broder, Samuel

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Matrix Metalloproteinase Inhibitor COL-3 in the Treatment of AIDS-Related Kaposi’s Sarcoma: A Phase I AIDS Malignancy Consortium Study von Cianfrocca, M.

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Phase 2 study of pegylated liposomal doxorubicin in combination with interleukin-12 for AIDS-related Kaposi sarcoma von Little, Richard F., Aleman, Karen, Kumar, Pallavi, Wyvill, Kathleen M., Pluda, James M., Read-Connole, Elizabeth, Wang, Victoria, Pittaluga, Stefania, Catanzaro, Andrew T., Steinberg, Seth M., Yarchoan, Robert

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Phase II Evaluation of Thalidomide in Patients With Metastatic Breast Cancer von BAIDAS, S. M, WINER, E. P, FLOCKHART, D, JOHNSON, M. D, HAWKINS, M. J, LIPPMAN, M. E, HAYES, D. F, FLEMING, G. F, HARRIS, L, PLUDA, J. M, CRAWFORD, J. G, YAMAUCHI, H, ISAACS, C, HANFELT, J, TEFFT, M

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Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: A phase I AIDS malignancy consortium study von CIANFROCCA, Mary, COOLEY, Timothy P, LEE, Jeannette Y, RUDEK, Michelle A, SCADDEN, David T, RATNER, Lee, PLUDA, James M, FIGG, William D, KROWN, Susan E, DEZUBE, Bruce J

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Phase II study of the antiangiogenesis agent thalidomide in recurrent or metastatic squamous cell carcinoma of the head and neck von Tseng, Jennifer E., Glisson, Bonnie S., Khuri, Fadlo R., Shin, Dong M., Myers, Jeffrey N., El‐Naggar, Adel K., Roach, Jennifer S., Ginsberg, Lawrence E., Thall, Peter F., Wang, Xuemei, Teddy, Stephanie, Lawhorn, Kristie N., Zentgraf, Rebecca E., Steinhaus, Ganene D., Pluda, James M., Abbruzzese, James L., Hong, Waun Ki, Herbst, Roy S.

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A Pharmacokinetically Guided Phase II Study of Carboxyamido-triazole in Androgen-independent Prostate Cancer von BAUER, K. S, FIGG, W. D, HAMILTON, J. M, JONES, E. C, PREMKUMAR, A, STEINBERG, S. M, DYER, V, LINEHAN, W. M, PLUDA, J. M, REED, E

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Using Positron Emission Tomography 2-Deoxy-2-[ 18F]Fluoro-D-Glucose, 11CO, and 15O-Water for Monitoring Androgen Independent Prostate Cancer von Kurdziel, Karen A, Figg, William D, Carrasquillo, Jorge A, Huebsch, Susan, Whatley, Millie, Sellers, David, Libutti, Steven K, Pluda, James M, Dahut, William, Reed, Edward, Bacharach, Stephen L

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Factors Involved in the Pharmacokinetics of COL-3, a Matrix Metalloproteinase Inhibitor, in Patients with Refractory Metastatic Cancer: Clinical and Experimental Studies von Rudek, Michelle A., Venitz, Jürgen, Ando, Yuichi, Reed, Eddie, Pluda, James M., Figg, William D.

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Reversible sideroblastic anemia associated with the tetracycline analogue COL‐3 von Rudek, Michelle A., Horne, McDonald, Figg, William D., Dahut, William, Dyer, Valerie, Pluda, James M., Reed, Eddie

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Development of angiogenesis inhibitors for cancer therapy von ECKHARDT, S. G, PLUDA, J. M

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Administration of Pentosan Polysulfate to Patients With Human Immunodeficiency Virus-Associated Kaposi's Sarcoma von Pluda, James M., Shay, Laura E., Foli, Andrea, Tannenbaum, Susan, Cohen, Philip J., Goldspiel, Barry R., Adamo, Debra, Cooper, Michael R., Broder, Samuel, Yarchoan, Robert

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Clinical trial designs for cytostatic agents von Ratain, M J, Stadler, W M

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