Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis von Bick, Alexander G., Pirruccello, James P., Griffin, Gabriel K., Gupta, Namrata, Gabriel, Stacey, Saleheen, Danish, Libby, Peter, Kathiresan, Sekar, Natarajan, Pradeep

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Genetics of 35 blood and urine biomarkers in the UK Biobank von Sinnott-Armstrong, Nasa, Tanigawa, Yosuke, Amar, David, Mars, Nina, Benner, Christian, Aguirre, Matthew, Venkataraman, Guhan Ram, Wainberg, Michael, Ollila, Hanna M., Kiiskinen, Tuomo, Havulinna, Aki S., Pirruccello, James P., Qian, Junyang, Shcherbina, Anna, Rodriguez, Fatima, Assimes, Themistocles L., Agarwala, Vineeta, Tibshirani, Robert, Hastie, Trevor, Ripatti, Samuli, Pritchard, Jonathan K., Daly, Mark J., Rivas, Manuel A.

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Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy von Pirruccello, James P., Bick, Alexander, Wang, Minxian, Chaffin, Mark, Friedman, Samuel, Yao, Jie, Guo, Xiuqing, Venkatesh, Bharath Ambale, Taylor, Kent D., Post, Wendy S., Rich, Stephen, Lima, Joao A. C., Rotter, Jerome I., Philippakis, Anthony, Lubitz, Steven A., Ellinor, Patrick T., Khera, Amit V., Kathiresan, Sekar, Aragam, Krishna G.

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Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women von Honigberg, Michael C, Zekavat, Seyedeh M, Niroula, Abhishek, Griffin, Gabriel K, Bick, Alexander G, Pirruccello, James P, Nakao, Tetsushi, Whitsel, Eric A, Farland, Leslie V, Laurie, Cecelia, Kooperberg, Charles, Manson, JoAnn E, Gabriel, Stacey, Libby, Peter, Reiner, Alexander P, Ebert, Benjamin L, Natarajan, Pradeep

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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus von Kathiresan, Sekar, Rader, Daniel J, Musunuru, Kiran, Strong, Alanna, Frank-Kamenetsky, Maria, Lee, Noemi E, Ahfeldt, Tim, Sachs, Katherine V, Li, Xiaoyu, Li, Hui, Kuperwasser, Nicolas, Ruda, Vera M, Pirruccello, James P, Muchmore, Brian, Prokunina-Olsson, Ludmila, Hall, Jennifer L, Schadt, Eric E, Morales, Carlos R, Lund-Katz, Sissel, Phillips, Michael C, Wong, Jamie, Cantley, William, Racie, Timothy, Ejebe, Kenechi G, Orho-Melander, Marju, Melander, Olle, Koteliansky, Victor, Fitzgerald, Kevin, Krauss, Ronald M, Cowan, Chad A

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Adjusting for common variant polygenic scores improves yield in rare variant association analyses von Jurgens, Sean J., Pirruccello, James P., Choi, Seung Hoan, Morrill, Valerie N., Chaffin, Mark, Lubitz, Steven A., Lunetta, Kathryn L., Ellinor, Patrick T.

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Genetics of myocardial interstitial fibrosis in the human heart and association with disease von Nauffal, Victor, Di Achille, Paolo, Klarqvist, Marcus D. R., Cunningham, Jonathan W., Hill, Matthew C., Pirruccello, James P., Weng, Lu-Chen, Morrill, Valerie N., Choi, Seung Hoan, Khurshid, Shaan, Friedman, Samuel F., Nekoui, Mahan, Roselli, Carolina, Ng, Kenney, Philippakis, Anthony A., Batra, Puneet, Ellinor, Patrick T., Lubitz, Steven A.

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Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass von Khurshid, Shaan, Lazarte, Julieta, Pirruccello, James P., Weng, Lu-Chen, Choi, Seung Hoan, Hall, Amelia W., Wang, Xin, Friedman, Samuel F., Nauffal, Victor, Biddinger, Kiran J., Aragam, Krishna G., Batra, Puneet, Ho, Jennifer E., Philippakis, Anthony A., Ellinor, Patrick T., Lubitz, Steven A.

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Deep Learning to Predict Cardiac Magnetic Resonance–Derived Left Ventricular Mass and Hypertrophy From 12-Lead ECGs von Khurshid, Shaan, Friedman, Samuel, Pirruccello, James P., Di Achille, Paolo, Diamant, Nathaniel, Anderson, Christopher D., Ellinor, Patrick T., Batra, Puneet, Ho, Jennifer E., Philippakis, Anthony A., Lubitz, Steven A.

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Selenoprotein deficiency disorder predisposes to aortic aneurysm formation von Schoenmakers, Erik, Marelli, Federica, Jørgensen, Helle F., Visser, W. Edward, Moran, Carla, Groeneweg, Stefan, Avalos, Carolina, Jurgens, Sean J., Figg, Nichola, Finigan, Alison, Wali, Neha, Agostini, Maura, Wardle-Jones, Hannah, Lyons, Greta, Rusk, Rosemary, Gopalan, Deepa, Twiss, Philip, Visser, Jacob J., Goddard, Martin, Nashef, Samer A. M., Heijmen, Robin, Clift, Paul, Sinha, Sanjay, Pirruccello, James P., Ellinor, Patrick T., Busch-Nentwich, Elisabeth M., Ramirez-Solis, Ramiro, Murphy, Michael P., Persani, Luca, Bennett, Martin, Chatterjee, Krishna

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Deep learning of left atrial structure and function provides link to atrial fibrillation risk von Pirruccello, James P., Di Achille, Paolo, Choi, Seung Hoan, Rämö, Joel T., Khurshid, Shaan, Nekoui, Mahan, Jurgens, Sean J., Nauffal, Victor, Kany, Shinwan, Ng, Kenney, Friedman, Samuel F., Batra, Puneet, Lunetta, Kathryn L., Palotie, Aarno, Philippakis, Anthony A., Ho, Jennifer E., Lubitz, Steven A., Ellinor, Patrick T.

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Machine learning enables new insights into genetic contributions to liver fat accumulation von Haas, Mary E., Pirruccello, James P., Friedman, Samuel N., Wang, Minxian, Emdin, Connor A., Ajmera, Veeral H., Simon, Tracey G., Homburger, Julian R., Guo, Xiuqing, Budoff, Matthew, Corey, Kathleen E., Zhou, Alicia Y., Philippakis, Anthony, Ellinor, Patrick T., Loomba, Rohit, Batra, Puneet, Khera, Amit V.

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Lp(a) (Lipoprotein[a]) Concentrations and Incident Atherosclerotic Cardiovascular Disease: New Insights From a Large National Biobank von Patel, Aniruddh P., Wang, Minxian, Pirruccello, James P., Ellinor, Patrick T., Ng, Kenney, Kathiresan, Sekar, Khera, Amit V.

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Machine learning-based markers for CAD von Elliott, Amanda, Pirruccello, James P

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Wearable accelerometer-derived physical activity and incident disease von Khurshid, Shaan, Weng, Lu-Chen, Nauffal, Victor, Pirruccello, James P., Venn, Rachael A., Al-Alusi, Mostafa A., Benjamin, Emelia J., Ellinor, Patrick T., Lubitz, Steven A.

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Genetic Association of Body Mass Index With Pathologic Left Ventricular Remodeling von Biddinger, Kiran J, Pirruccello, James P, Khurshid, Shaan, Natarajan, Pradeep, Ho, Jennifer E, Lubitz, Steven A, Ellinor, Patrick T, Aragam, Krishna G

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Cardiovascular and Kidney Outcomes Across the Glycemic Spectrum: Insights From the UK Biobank von Honigberg, Michael C, Zekavat, Seyedeh M, Pirruccello, James P, Natarajan, Pradeep, Vaduganathan, Muthiah

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“Road Map” to Improving Enrollment in Cardiac Rehabilitation: Identifying Barriers and Evaluating Alternatives von Pirruccello, James P., Traynor, Kathleen, Aragam, Krishna G.

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Genetics and mechanisms of thoracic aortic disease von Chou, Elizabeth, Pirruccello, James P., Ellinor, Patrick T., Lindsay, Mark E.

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How Will Machine Learning Inform the Clinical Care of Atrial Fibrillation? von Siontis, Konstantinos C., Yao, Xiaoxi, Pirruccello, James P., Philippakis, Anthony A., Noseworthy, Peter A.

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