Site selective C–H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy von Bhowmik, Srijita, Galeta, Juraj, Havel, Václav, Nelson, Melissa, Faouzi, Abdelfattah, Bechand, Benjamin, Ansonoff, Mike, Fiala, Tomas, Hunkele, Amanda, Kruegel, Andrew C., Pintar, John. E., Majumdar, Susruta, Javitch, Jonathan A., Sames, Dalibor

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7‑Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects von Kruegel, Andrew C, Uprety, Rajendra, Grinnell, Steven G, Langreck, Cory, Pekarskaya, Elizabeth A, Le Rouzic, Valerie, Ansonoff, Michael, Gassaway, Madalee M, Pintar, John E, Pasternak, Gavril W, Javitch, Jonathan A, Majumdar, Susruta, Sames, Dalibor

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Epidermal stem cells are retained in vivo throughout skin aging von Giangreco, Adam, Qin, Mei, Pintar, John E., Watt, Fiona M.

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Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models von Havel, Václav, Kruegel, Andrew C., Bechand, Benjamin, McIntosh, Scot, Stallings, Leia, Hodges, Alana, Wulf, Madalee G., Nelson, Mel, Hunkele, Amanda, Ansonoff, Michael, Pintar, John E., Hwu, Christopher, Ople, Rohini S., Abi-Gerges, Najah, Zaidi, Saheem A., Katritch, Vsevolod, Yang, Mu, Javitch, Jonathan A., Majumdar, Susruta, Hemby, Scott E., Sames, Dalibor

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A Role for Heterodimerization of μ and δ Opiate Receptors in Enhancing Morphine Analgesia von Gomes, Ivone, Gupta, Achla, Filipovska, Julija, Szeto, Hazel H., Pintar, John E., Devi, Lakshmi A., Snyder, Solomon H.

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GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding von Gomes, Ivone, Aryal, Dipendra K., Wardman, Jonathan H., Gupta, Achla, Gagnidze, Khatuna, Rodriguiz, Ramona M., Kumar, Sanjai, Wetsel, William C., Pintar, John E., Fricker, Lloyd D., Devi, Lakshmi A.

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IGF-II Promotes Stemness of Neural Restricted Precursors von Ziegler, Amber N., Schneider, Joel S., Qin, Mei, Tyler, William A., Pintar, John E., Fraidenraich, Diego, Wood, Teresa L., Levison, Steven W.

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IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth von Lofqvist, Chatarina, Chen, Jing, Connor, Kip M, Smith, Alexandra C.H, Aderman, Christopher M, Liu, Nan, Pintar, John E, Ludwig, Thomas, Hellstrom, Ann, Smith, Lois E.H

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IGF Binding Protein-4 is Required for the Growth Effects of Glucagon-Like Peptide-2 in Murine Intestine von Austin, Kaori, Imam, Nuvair A, Pintar, John E, Brubaker, Patricia L

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Insulin-Like Growth Factor (IGF) Binding Protein-4 Is Both a Positive and Negative Regulator of IGF Activity in Vivo von Ning, Yun, Schuller, Alwin G. P, Conover, Cheryl A, Pintar, John E

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Diminished Growth and Enhanced Glucose Metabolism in Triple Knockout Mice Containing Mutations of Insulin-Like Growth Factor Binding Protein-3, -4, and -5 von Ning, Yun, Schuller, Alwin G. P, Bradshaw, Sheri, Rotwein, Peter, Ludwig, Thomas, Frystyk, Jan, Pintar, John E

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Circadian integration of glutamatergic signals by little SAAS in novel suprachiasmatic circuits von Atkins, Jr, Norman, Mitchell, Jennifer W, Romanova, Elena V, Morgan, Daniel J, Cominski, Tara P, Ecker, Jennifer L, Pintar, John E, Sweedler, Jonathan V, Gillette, Martha U

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Mexneurin is a novel precursor of peptides in the central nervous system of rodents von Matus‐Ortega, Maura E., Leff Gelman, Philippe, Calva‐Nieves, Juan C., Flores‐Zamora, Anabel, Salazar‐Juárez, Alberto, Torner‐Aguilar, Carlos‐Alejandro, Gamba, Gerardo, De Los Heros, Paola, Peng, Bonnie, Pintar, John E., Gompf, Heinrich S., Allen, Charles N., Antón‐Palma, Benito

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The biology of Nociceptin/Orphanin FQ(N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence von WITKIN, Jeffrey M, STATNICK, Michael A, RORICK-KEHN, Linda M, PINTAR, John E, ANSONOFF, Michael, YANYUN CHEN, TUCKER, R. Craig, CICCOCIOPPO, Roberto

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The Behavioral Effects of the Antidepressant Tianeptine Require the Mu-Opioid Receptor von Samuels, Benjamin Adam, Nautiyal, Katherine M, Kruegel, Andrew C, Levinstein, Marjorie R, Magalong, Valerie M, Gassaway, Madalee M, Grinnell, Steven G, Han, Jaena, Ansonoff, Michael A, Pintar, John E, Javitch, Jonathan A, Sames, Dalibor, Hen, René

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Exogenous GLP-2 and IGF-I induce a differential intestinal response in IGF binding protein-3 and -5 double knockout mice von Murali, Sangita G, Brinkman, Adam S, Solverson, Patrick, Pun, Wing, Pintar, John E, Ney, Denise M

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Kappa opioid receptor contributes to EGF-stimulated neurite extension in development von Tsai, Nien-Pei, Tsui, Yao-Chen, Pintar, John E, Loh, Horace H, Wei, Li-Na

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Contribution of the Opioid System to the Antidepressant Effects of Fluoxetine von Carazo-Arias, Elena, Nguyen, Phi T., Kass, Marley, Jee, Hyun Jung, Nautiyal, Katherine M., Magalong, Valerie, Coie, Lilian, Andreu, Valentine, Gergues, Mark M., Khalil, Huzefa, Akil, Huda, Arcego, Danusa Mar, Meaney, Michael, Anacker, Christoph, Samuels, Benjamin A., Pintar, John E., Morozova, Irina, Kalachikov, Sergey, Hen, Rene

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Prolonged Kappa Opioid Receptor Phosphorylation Mediated by G-protein Receptor Kinase Underlies Sustained Analgesic Tolerance von McLaughlin, Jay P., Myers, Lisa C., Zarek, Paul E., Caron, Marc G., Lefkowitz, Robert J., Czyzyk, Traci A., Pintar, John E., Chavkin, Charles

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PAPA-1 Is a Nuclear Binding Partner of IGFBP-2 and Modulates Its Growth-Promoting Actions von Miyako, Kenichi, Cobb, Laura J, Francis, Malik, Huang, Alden, Peng, Bonnie, Pintar, John E, Ariga, Hiroyoshi, Cohen, Pinchas

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