Applications of organocatalysed visible-light photoredox reactions for medicinal chemistry von Bogdos, Michael K, Pinard, Emmanuel, Murphy, John A

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Discovery of Risdiplam, a Selective Survival of Motor Neuron‑2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA) von Ratni, Hasane, Ebeling, Martin, Baird, John, Bendels, Stefanie, Bylund, Johan, Chen, Karen S, Denk, Nora, Feng, Zhihua, Green, Luke, Guerard, Melanie, Jablonski, Philippe, Jacobsen, Bjoern, Khwaja, Omar, Kletzl, Heidemarie, Ko, Chien-Ping, Kustermann, Stefan, Marquet, Anne, Metzger, Friedrich, Mueller, Barbara, Naryshkin, Nikolai A, Paushkin, Sergey V, Pinard, Emmanuel, Poirier, Agnès, Reutlinger, Michael, Weetall, Marla, Zeller, Andreas, Zhao, Xin, Mueller, Lutz

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Glycine Transporter Type I (GlyT1) Inhibitor, Bitopertin: A Journey from Lab to Patient von Pinard, Emmanuel, Borroni, Edilio, Koerner, Annette, Umbricht, Daniel, Alberati, Daniela

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Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophrenia von Alberati, Daniela, Moreau, Jean-Luc, Lengyel, Judith, Hauser, Nicole, Mory, Roland, Borroni, Edilio, Pinard, Emmanuel, Knoflach, Frederic, Schlotterbeck, Götz, Hainzl, Dominik, Wettstein, Joseph G.

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Biochemical and Electrophysiological Characterization of Almorexant, a Dual Orexin 1 Receptor (OX1)/Orexin 2 Receptor (OX2) Antagonist: Comparison with Selective OX1 and OX2 Antago... von Malherbe, Pari, Borroni, Edilio, Pinard, Emmanuel, Wettstein, Joseph G, Knoflach, Frédéric

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Selective GlyT1 Inhibitors: Discovery of [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678... von Pinard, Emmanuel, Alanine, Alexander, Alberati, Daniela, Bender, Markus, Borroni, Edilio, Bourdeaux, Patrick, Brom, Virginie, Burner, Serge, Fischer, Holger, Hainzl, Dominik, Halm, Remy, Hauser, Nicole, Jolidon, Synese, Lengyel, Judith, Marty, Hans-Peter, Meyer, Thierry, Moreau, Jean-Luc, Mory, Roland, Narquizian, Robert, Nettekoven, Mathias, Norcross, Roger D, Puellmann, Bernd, Schmid, Philipp, Schmitt, Sebastien, Stalder, Henri, Wermuth, Roger, Wettstein, Joseph G, Zimmerli, Daniel

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BACE1 inhibitors: A head group scan on a series of amides von Woltering, Thomas J., Wostl, Wolfgang, Hilpert, Hans, Rogers-Evans, Mark, Pinard, Emmanuel, Mayweg, Alexander, Göbel, Martin, Banner, David W., Benz, Jörg, Travagli, Massimiliano, Pollastrini, Martina, Marconi, Guido, Gabellieri, Emanuele, Guba, Wolfgang, Mauser, Harald, Andreini, Matteo, Jacobsen, Helmut, Power, Eoin, Narquizian, Robert

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The Voltage-dependent Anion Channel Is the Target for a New Class of Inhibitors of the Mitochondrial Permeability Transition Pore von Cesura, Andrea M., Pinard, Emmanuel, Schubenel, Robert, Goetschy, Valerie, Friedlein, Arno, Langen, Hanno, Polcic, Peter, Forte, Michael A., Bernardi, Paolo, Kemp, John A.

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Structural insights into the inhibition of glycine reuptake von Shahsavar, Azadeh, Stohler, Peter, Bourenkov, Gleb, Zimmermann, Iwan, Siegrist, Martin, Guba, Wolfgang, Pinard, Emmanuel, Sinning, Steffen, Seeger, Markus A., Schneider, Thomas R., Dawson, Roger J. P., Nissen, Poul

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Discovery of Balovaptan, a Vasopressin la Receptor Antagonist for the Treatment of Autism Spectrum Disorder von Schnider, Patrick, Bissantz, Caterina, Bruns, Andreas, Dolente, Cosimo, Goetschi, Erwin, Jakob-Roetne, Roland, Kuennecke, Basil, Mueggler, Thomas, Muster, Wolfgang, Parrott, Neil, Pinard, Emmanuel, Ratni, Hasane, Risterucci, Celine, Rogers-Evans, Mark, von Kienlin, Markus, Grundschober, Christophe

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A Real-World Perspective on Molecular Design von Kuhn, Bernd, Guba, Wolfgang, Hert, Jérôme, Banner, David, Bissantz, Caterina, Ceccarelli, Simona, Haap, Wolfgang, Körner, Matthias, Kuglstatter, Andreas, Lerner, Christian, Mattei, Patrizio, Neidhart, Werner, Pinard, Emmanuel, Rudolph, Markus G, Schulz-Gasch, Tanja, Woltering, Thomas, Stahl, Martin

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Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy von Ratni, Hasane, Karp, Gary M, Weetall, Marla, Naryshkin, Nikolai A, Paushkin, Sergey V, Chen, Karen S, McCarthy, Kathleen D, Qi, Hongyan, Turpoff, Anthony, Woll, Matthew G, Zhang, Xiaoyan, Zhang, Nanjing, Yang, Tianle, Dakka, Amal, Vazirani, Priya, Zhao, Xin, Pinard, Emmanuel, Green, Luke, David-Pierson, Pascale, Tuerck, Dietrich, Poirier, Agnes, Muster, Wolfgang, Kirchner, Stephan, Mueller, Lutz, Gerlach, Irene, Metzger, Friedrich

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Structural insights into the inhibition of glycine reuptake von Shahsavar, Azadeh, Stohler, Peter, Bourenkov, Gleb, Zimmermann, Iwan, Siegrist, Martin, Guba, Wolfgang, Pinard, Emmanuel, Sinning, Steffen, Seeger, Markus A, Schneider, Thomas R, Dawson, Roger J P, Nissen, Poul

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β‑Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease von Hilpert, Hans, Guba, Wolfgang, Woltering, Thomas J, Wostl, Wolfgang, Pinard, Emmanuel, Mauser, Harald, Mayweg, Alexander V, Rogers-Evans, Mark, Humm, Roland, Krummenacher, Daniela, Muser, Thorsten, Schnider, Christian, Jacobsen, Helmut, Ozmen, Laurence, Bergadano, Alessandra, Banner, David W, Hochstrasser, Remo, Kuglstatter, Andreas, David-Pierson, Pascale, Fischer, Holger, Polara, Alessandra, Narquizian, Robert

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Discovery of Orally Available and Brain Penetrant AEP Inhibitors von Krummenacher, Daniela, He, Weiping, Kuhn, Bernd, Schnider, Christian, Beurier, Angélica, Brom, Virginie, Sivasothy, Thulase, Marty, Christine, Tosstorff, Andreas, Hewings, David S., Mesch, Stefanie, Pinard, Emmanuel, Brändlin, Mathis, Hochstrasser, Remo, Westwood, Paul, Rothe, Judith, Kronenberger, Alexandra, Morandi, Federica, Gutbier, Simon, Schuler, Angelika, Heer, Dominik, Gloria, Ludivine Esteves, Joedicke, Lisa, Rudolph, Markus G., Müller, Lutz, Grüninger, Fiona, Baumann, Karlheinz, Kaniyappan, Senthilvelrajan, Manevski, Nenad, Bartels, Björn

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Discovery of a Novel Class of Survival Motor Neuron 2 Splicing Modifiers for the Treatment of Spinal Muscular Atrophy von Pinard, Emmanuel, Green, Luke, Reutlinger, Michael, Weetall, Marla, Naryshkin, Nikolai A, Baird, John, Chen, Karen S, Paushkin, Sergey V, Metzger, Friedrich, Ratni, Hasane

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Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum Disorder von Schnider, Patrick, Bissantz, Caterina, Bruns, Andreas, Dolente, Cosimo, Goetschi, Erwin, Jakob-Roetne, Roland, Künnecke, Basil, Mueggler, Thomas, Muster, Wolfgang, Parrott, Neil, Pinard, Emmanuel, Ratni, Hasane, Risterucci, Céline, Rogers-Evans, Mark, von Kienlin, Markus, Grundschober, Christophe

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The Mitochondrial Effects of Small Organic Ligands of BCL-2 von Milanesi, Eva, Costantini, Paola, Gambalunga, Alberto, Colonna, Raffaele, Petronilli, Valeria, Cabrelle, Anna, Semenzato, Gianpietro, Cesura, Andrea M., Pinard, Emmanuel, Bernardi, Paolo

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Pharmacological evaluation of a novel assay for detecting glycine transporter 1 inhibitors and their antipsychotic potential von Alberati, Daniela, Moreau, Jean-Luc, Mory, Roland, Pinard, Emmanuel, Wettstein, Joseph G.

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[11C]-RO5013853: a New PET Radioligand for the Glycine Transporter TYPE 1 von Wong, Dean, Ostrowitzki, Susanne, Zhou, Yun, Alberati, Daniela, Pinard, Emmanuel, Raymont, Vanessa, Martin-facklam, Meret, Hofmann, Carsten, Parkar, Nikhat, Brasic, James, Hilton, John, Dannals, Robert, Borroni, Edilio

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