Discovery and Selection of TMC114, a Next Generation HIV-1 Protease Inhibitor von Surleraux, Dominique L. N. G, Tahri, Abdellah, Verschueren, Wim G, Pille, Geert M. E, de Kock, Herman A, Jonckers, Tim H. M, Peeters, Anik, De Meyer, Sandra, Azijn, Hilde, Pauwels, Rudi, de Bethune, Marie-Pierre, King, Nancy M, Prabu-Jeyabalan, Moses, Schiffer, Celia A, Wigerinck, Piet B. T. P

Volltext

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level... von Cassini, Alessandro, Högberg, Liselotte Diaz, Plachouras, Diamantis, Quattrocchi, Annalisa, Hoxha, Ana, Simonsen, Gunnar Skov, Colomb-Cotinat, Mélanie, Kretzschmar, Mirjam E, Devleesschauwer, Brecht, Cecchini, Michele, Ouakrim, Driss Ait, Oliveira, Tiago Cravo, Struelens, Marc J, Suetens, Carl, Monnet, Dominique L, Strauss, Reinhild, Mertens, Karl, Struyf, Thomas, Catry, Boudewijn, Latour, Katrien, Ivanov, Ivan N, Dobreva, Elina G, Tambic Andraševic, Arjana, Soprek, Silvija, Budimir, Ana, Paphitou, Niki, Žemlicková, Helena, Schytte Olsen, Stefan, Wolff Sönksen, Ute, Märtin, Pille, Ivanova, Marina, Lyytikäinen, Outi, Jalava, Jari, Coignard, Bruno, Eckmanns, Tim, Abu Sin, Muna, Haller, Sebastian, Daikos, George L, Gikas, Achilleas, Tsiodras, Sotirios, Kontopidou, Flora, Tóth, Ákos, Hajdu, Ágnes, Guólaugsson, Ólafur, Kristinsson, Karl G, Murchan, Stephen, Burns, Karen, Pezzotti, Patrizio, Gagliotti, Carlo, Dumpis, Uga, Liuimiene, Agne, Perrin, Monique, Borg, Michael A, de Greeff, Sabine C, Monen, Jos CM, Koek, Mayke BG, Elstrøm, Petter, Zabicka, Dorota, Deptula, Aleksander, Hryniewicz, Waleria, Caniça, Manuela, Nogueira, Paulo Jorge, Fernandes, Paulo André, Manageiro, Vera, Popescu, Gabriel A, Serban, Roxana I, Schréterová, Eva, Litvová, Slavka, Štefkovicová, Mária, Kolman, Jana, Klavs, Irena, Korošec, Aleš, Aracil, Belén, Asensio, Angel, Pérez-Vázquez, María, Billström, Hanna, Larsson, Sofie, Reilly, Jacqui S, Johnson, Alan, Hopkins, Susan

Volltext

Formation of Well-Defined, Functional Nanotubes via Osmotically Induced Shape Transformation of Biodegradable Polymersomes von Abdelmohsen, Loai K. E. A, Williams, David S, Pille, Jan, Ozel, Sema G, Rikken, Roger S. M, Wilson, Daniela A, van Hest, Jan C. M

Volltext

((BICYCLIC HETEROCYCLYL)-METHYL AND HETERO)-SUBSTITUTED HEXAHYDRO-1H-AZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS von DIELS, G S M, PILLE G M E, JANSSENS, F E

Volltext bestellen

Design and Optimization of Tricyclic Phtalimide Analogues as Novel Inhibitors of HIV-1 Integrase von Verschueren, Wim G, Dierynck, Inge, Amssoms, Katie I. E, Hu, Lili, Boonants, Paul M. J. G, Pille, Geert M. E, Daeyaert, Frits F. D, Hertogs, Kurt, Surleraux, Dominique L. N. G, Wigerinck, Piet B. T. P

Volltext

Design of HIV-1 Protease Inhibitors Active on Multidrug-Resistant Virus von Surleraux, Dominique L. N. G, de Kock, Herman A, Verschueren, Wim G, Pille, Geert M. E, Maes, Louis J. R, Peeters, Anik, Vendeville, Sandrine, De Meyer, Sandra, Azijn, Hilde, Pauwels, Rudi, de Bethune, Marie-Pierre, King, Nancy M, Prabu-Jeyabalan, Moses, Schiffer, Celia A, Wigerinck, Piet B. T. P

Volltext

Parkinson's disease in GTP cyclohydrolase 1 mutation carriers von MENCACCI, Niccolò E, ISAIAS, Ioannis U, NOYCE, Alastair J, MOK, Kin Y, OPLADEN, Thomas, KUNSTMANN, Erdmute, HODECKER, Sybille, MÜNCHAU, Alexander, VOLKMANN, Jens, SAMNICK, Samuel, SIDLE, Katie, NANJI, Tina, REICH, Martin M, SWEENEY, Mary G, HOULDEN, Henry, BATLA, Amit, ZECCHINELLI, Anna L, PEZZOLI, Gianni, MAROTTA, Giorgio, LEES, Andrew, ALEGRIA, Paulo, KRACK, Paul, CORMIER-DEQUAIRE, Florence, GANOS, Christos, LESAGE, Suzanne, BRICE, Alexis, HEUTINK, Peter, GASSER, Thomas, LUBBE, Steven J, MORRIS, Huw R, TABA, Pille, KOKS, Sulev, MAJOUNIE, Elisa, GIBBS, J. Raphael, PLAGNOL, Vincent, SINGLETON, Andrew, HARDY, John, KLEBE, Stephan, BHATIA, Kailash P, WOOD, Nicholas W, POLKE, James M, BRAS, Jose, HERSHESON, Joshua, STAMELOU, Maria, PITTMAN, Alan M

Volltext

The Y-chromosome tree bursts into leaf: 13,000 high-confidence SNPs covering the majority of known clades von Hallast, Pille, Batini, Chiara, Zadik, Daniel, Maisano Delser, Pierpaolo, Wetton, Jon H, Arroyo-Pardo, Eduardo, Cavalleri, Gianpiero L, de Knijff, Peter, Destro Bisol, Giovanni, Dupuy, Berit Myhre, Eriksen, Heidi A, Jorde, Lynn B, King, Turi E, Larmuseau, Maarten H, López de Munain, Adolfo, López-Parra, Ana M, Loutradis, Aphrodite, Milasin, Jelena, Novelletto, Andrea, Pamjav, Horolma, Sajantila, Antti, Schempp, Werner, Sears, Matt, Tolun, Aslıhan, Tyler-Smith, Chris, Van Geystelen, Anneleen, Watkins, Scott, Winney, Bruce, Jobling, Mark A

Volltext

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13 von Barton, Anne, Thomson, Wendy, Ke, Xiayi, Eyre, Steve, Hinks, Anne, Bowes, John, Plant, Darren, Gibbons, Laura J, Wilson, Anthony G, Bax, Deborah E, Morgan, Ann W, Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M, Wordsworth, Paul, Harrison, Pille, Worthington, Jane

Volltext

Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility von Barton, Anne, Thomson, Wendy, Ke, Xiayi, Eyre, Steve, Hinks, Anne, Bowes, John, Gibbons, Laura, Plant, Darren, Wilson, Anthony G., Marinou, Ioanna, Morgan, Ann, Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M., Wordsworth, Paul, Harrison, Pille, Worthington, Jane

Volltext

The complete sequence and comparative analysis of ape sex chromosomes von Makova, Kateryna D., Pickett, Brandon D., Harris, Robert S., Hartley, Gabrielle A., Cechova, Monika, Pal, Karol, Nurk, Sergey, Yoo, DongAhn, Li, Qiuhui, Hebbar, Prajna, McGrath, Barbara C., Antonacci, Francesca, Aubel, Margaux, Biddanda, Arjun, Borchers, Matthew, Bornberg-Bauer, Erich, Bouffard, Gerard G., Brooks, Shelise Y., Carbone, Lucia, Carrel, Laura, Carroll, Andrew, Chang, Pi-Chuan, Chin, Chen-Shan, Cook, Daniel E., Craig, Sarah J. C., de Gennaro, Luciana, Diekhans, Mark, Dutra, Amalia, Garcia, Gage H., Grady, Patrick G. S., Green, Richard E., Haddad, Diana, Hallast, Pille, Harvey, William T., Hickey, Glenn, Hillis, David A., Hoyt, Savannah J., Jeong, Hyeonsoo, Kamali, Kaivan, Pond, Sergei L. Kosakovsky, LaPolice, Troy M., Lee, Charles, Lewis, Alexandra P., Loh, Yong-Hwee E., Masterson, Patrick, McGarvey, Kelly M., McCoy, Rajiv C., Medvedev, Paul, Miga, Karen H., Munson, Katherine M., Pak, Evgenia, Paten, Benedict, Pinto, Brendan J., Potapova, Tamara, Rhie, Arang, Rocha, Joana L., Ryabov, Fedor, Ryder, Oliver A., Sacco, Samuel, Shafin, Kishwar, Shepelev, Valery A., Slon, Viviane, Solar, Steven J., Storer, Jessica M., Sudmant, Peter H., Sweetalana, Sweeten, Alex, Tassia, Michael G., Thibaud-Nissen, Françoise, Ventura, Mario, Wilson, Melissa A., Young, Alice C., Zeng, Huiqing, Zhang, Xinru, Szpiech, Zachary A., Huber, Christian D., Gerton, Jennifer L., Yi, Soojin V., Schatz, Michael C., Alexandrov, Ivan A., Koren, Sergey, O’Neill, Rachel J., Eichler, Evan E., Phillippy, Adam M.

Volltext

Association of Body Mass Index and Parkinson Disease: A Bidirectional Mendelian Randomization Study von Domenighetti, Cloé, Sugier, Pierre-Emmanuel, Ashok Kumar Sreelatha, Ashwin, Schulte, Claudia, Grover, Sandeep, Portugal, Berta, Lee, Pei-Chen, May, Patrick, Bobbili, Dheeraj, Radivojkov Blagojevic, Milena, Lichtner, Peter, Singleton, Andrew B, Hernandez, Dena, Edsall, Connor, Mellick, George D, Zimprich, Alexander A, Pirker, Walter, Rogaeva, Ekaterina A, Lang, Anthony E, Koks, Sulev, Taba, Pille, Lesage, Suzanne, Brice, Alexis, Corvol, Jean-Christophe, Chartier-Harlin, Marie-Christine, Mutez, Eugenie, Brockmann, Kathrin, Deutschlander, Angela B, Hadjigeorgiou, Georgios M, Dardiotis, Efthimios, Stefanis, Leonidas, Simitsi, Athina Maria, Valente, Enza Maria, Petrucci, Simona, Straniero, Letizia, Zecchinelli, Anna L, Pezzoli, Gianni, Brighina, Laura, Ferrarese, Carlo, Annesi, Grazia, Quattrone, Andrea, Gagliardi, Monica, Matsuo, Hirotaka, Nakayama, Akiyoshi, Hattori, Nobutaka, Nishioka, Kenya, Chung, Sun Ju, Kim, Yun Joong, Kolber, Pierre, Van De Warrenburg, Bart P C, Bloem, Bastiaan R, Toft, Mathias, Pihlstrøm, Lasse, Correia Guedes, Leonor, Ferreira, Joaquim J, Bardien, Soraya, Carr, Jonathan, Tolosa, Eduardo, Ezquerra, Mario, Pastor, Pau, Diez-Fairen, Monica, Wirdefeldt, Karin, Pedersen, Nancy L, Ran, Caroline, Belin, Andrea C, Puschmann, Andreas, Hellberg, Clara, Clarke, Carl E, Morrison, Karen E, Tan, Manuela M, Krainc, Dimitri, Burbulla, Lena F, Farrer, Matthew, Kruger, Rejko, Gasser, Thomas, Sharma, Manu, Elbaz, Alexis

Volltext

Genome-wide Association and Meta-analysis of Age-at-Onset in Parkinson Disease: Evidence From COURAGE-PD Consortium von Grover, Sandeep, Ashwin, Ashok Kumar Sreelatha, Pihlstrom, Lasse, Domenighetti, Cloé, Schulte, Claudia, Sugier, Pierre-Emmanuel, Radivojkov-Blagojevic, Milena, Lichtner, Peter, Mohamed, Océane, Portugal, Berta, Landoulsi, Zied, May, Patrick, BOBBILI, Dheeraj, Edsall, Connor, Bartusch, Felix, Hanussek, Maximilian, Krüger, Jens, Hernandez, Dena G, Blauwendraat, Cornelis, Mellick, George D, Zimprich, Alexander, Pirker, Walter, Tan, Manuela, Rogaeva, Ekaterina, Lang, Anthony, Koks, Sulev, Taba, Pille, Lesage, Suzanne, Brice, Alexis, Corvol, Jean-Christophe, Chartier-Harlin, Marie-Christine, Mutez, Eugenie, Brockmann, Kathrin, Deutschländer, Angela B, Hadjigeorgiou, Georges M, Dardiotis, Efthimos, Stefanis, Leonidas, Simitsi, Athina Maria, Valente, Enza Maria, Petrucci, Simona, Straniero, Letizia, Zecchinelli, Anna, Pezzoli, Gianni, Brighina, Laura, Ferrarese, Carlo, Annesi, Grazia, Quattrone, Andrea, Gagliardi, Monica, Burbulla, Lena F, Matsuo, Hirotaka, Kawamura, Yusuke, Hattori, Nobutaka, Nishioka, Kenya, Chung, Sun Ju, Kim, Yun Joong, Pavelka, Lukas, van de Warrenburg, Bart PC, Bloem, Bastiaan R, Singleton, Andrew B., Aasly, Jan, Toft, Mathias, Guedes, Leonor Correia, Ferreira, Joaquim J, Bardien, Soraya, Carr, Jonathan, Tolosa, Eduardo, Ezquerra, Mario, Pastor, Pau, Diez-Fairen, Monica, Wirdefeldt, Karin, Pedersen, Nancy L, Ran, Caroline, Belin, Andrea C, Puschmann, Andreas, Hellberg, Clara, Clarke, Carl E, Morrison, Karen E, Krainc, Dimitri, Farrer, Matt J, Kruger, Rejko, Elbaz, Alexis, Gasser, Thomas, Sharma, Manu

Volltext

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23 von Orozco, Gisela, Hinks, Anne, Eyre, Steve, Ke, Xiayi, Gibbons, Laura J., Bowes, John, Flynn, Edward, Martin, Paul, Wilson, Anthony G., Bax, Deborah E., Morgan, Ann W., Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M., Wordsworth, Paul, Harrison, Pille, Thomson, Wendy, Barton, Anne, Worthington, Jane

Volltext

Octa-arginine boosts the penetration of elastin-like polypeptide nanoparticles in 3D cancer models von van Oppen, Lisanne M.P.E., Pille, Jan, Stuut, Christiaan, van Stevendaal, Marleen, van der Vorm, Lisa N., Smeitink, Jan A.M., Koopman, Werner J.H., Willems, Peter H.G.M., van Hest, Jan C.M., Brock, Roland

Volltext

Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors von Liu, Hui, Dehestani, Mohammad, Blauwendraat, Cornelis, Makarious, Mary B., Leonard, Hampton, Kim, Jonggeol J., Schulte, Claudia, Noyce, Alastair, Jacobs, Benjamin M., Foote, Isabelle, Sharma, Manu, Koks, Sulev, Mellick, George D, Pirker, Walter, Zimprich, Alexander, Lang, Anthony E, Rogaeva, Ekaterina, Taba, Pille, Brice, Alexis, Chartier‐Harlin, Marie‐Christine, Corvol, Jean‐Christophe, Domenighetti, Cloé, Elbaz, Alexis, Lesage, Suzanne, Mutez, Eugenie, Sugier, Pierre‐Emmanuel, Sreelatha, Ashwin Ashok Kumar, Grover, Sandeep, Brockmann, Kathrin, Deutschländer, Angela B, Gasser, Thomas, Krüger, Jens, Lichtner, Peter, Radivojkov‐Blagojevic, Milena, Schulte, Claudia, Sharma, Manu, Dardiotis, Efthimos, Hadjigeorgiou, Georges M, Simitsi, Athina Maria, Stefanis, Leonidas, Annesi, Grazia, Brighina, Laura, Ferrarese, Carlo, Petrucci, Simona, Pezzoli, Gianni, Quattrone, Andrea, Straniero, Letizia, Gagliardi, Monica, Valente, Enza Maria, Zecchinelli, Anna, Hattori, Nobutaka, Nakayama, Akiyoshi, Matsuo, Hirotaka, Nishioka, Kenya, Bobbili, Dheeraj, Kruger, Rejko, Landoulsi, Zied, May, Patrick, Pavelka, Lukas, Bloem, Bastiaan R, Warrenburg, Bart PC, Aasly, Jan, Pihlstrøm, Lasse, Toft, Mathias, Ferreira, Joaquim J, Guedes, Leonor Correia, Bardien, Soraya, Carr, Jonathan, Chung, Sun Ju, Kim, Yun Joong, Diez‐Fairen, Monica, Ezquerra, Mario, Pastor, Pau, Tolosa, Eduardo, Belin, Andrea C, Pedersen, Nancy L, Puschmann, Andreas, Ran, Caroline, Rödström, Emil Y, Wirdefeldt, Karin, Clarke, Carl E, Morrison, Karen E, Tan, Manuela, Edsall, Connor, Farrer, Matt J, Krainc, Dimitri, Singleton, Andrew B, Burbulla, Lena F, Hernandez, Dena G, Nalls, Mike, Singleton, Andrew, Gasser, Thomas, Bandres‐Ciga, Sara

Volltext

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease von Eyre, Stephen, Hinks, Anne, Bowes, John, Flynn, Edward, Martin, Paul, Wilson, Anthony G, Morgan, Ann W, Emery, Paul, Steer, Sophia, Hocking, Lynne J, Reid, David M, Harrison, Pille, Wordsworth, Paul, Thomson, Wendy, Worthington, Jane, Barton, Anne

Volltext

PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian Population von Burr, Marian L, Naseem, Haris, Hinks, Anne, Eyre, Steve, Gibbons, Laura, Bowes, John, Consortium, BIRAC, Consortium, YEAR, Wilson, Anthony G, Maxwell, James, Morgan, Ann W, Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M, Wordsworth, B Paul, Harrison, Pille, Thomson, Wendy, Worthington, Jane, Barton, Anne

Volltext

Caregiver Education in Parkinson's Disease: Formative Evaluation of a Standardized Program in Seven European Countries von A'Campo, L. E. I., Spliethoff-Kamminga, N. G. A., Macht, M., Roos, R. A. C.

Volltext

Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study von Orozco, Gisela, Eyre, Steve, Hinks, Anne, Ke, Xiayi, Wilson, Anthony G, Bax, Deborah E, Morgan, Ann W, Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M, Wordsworth, Paul, Harrison, Pille, Thomson, Wendy, Barton, Anne, Worthington, Jane

Volltext